ZA201701732B - Method and device for separating immiscible liquids to effectively isolate at least one of the liquids - Google Patents

Method and device for separating immiscible liquids to effectively isolate at least one of the liquids

Info

Publication number
ZA201701732B
ZA201701732B ZA2017/01732A ZA201701732A ZA201701732B ZA 201701732 B ZA201701732 B ZA 201701732B ZA 2017/01732 A ZA2017/01732 A ZA 2017/01732A ZA 201701732 A ZA201701732 A ZA 201701732A ZA 201701732 B ZA201701732 B ZA 201701732B
Authority
ZA
South Africa
Prior art keywords
liquids
effectively isolate
separating immiscible
immiscible liquids
separating
Prior art date
Application number
ZA2017/01732A
Inventor
Hans VERMAAS Eric
Hage Matthew
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of ZA201701732B publication Critical patent/ZA201701732B/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/088—Microfluidic devices comprising semi-permeable flat membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02—Separation of non-miscible liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02—Separation of non-miscible liquids
    • B01D17/0202—Separation of non-miscible liquids by ab- or adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02—Separation of non-miscible liquids
    • B01D17/0208—Separation of non-miscible liquids by sedimentation
    • B01D17/0214—Separation of non-miscible liquids by sedimentation with removal of one of the phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/08—Thickening liquid suspensions by filtration
    • B01D17/085—Thickening liquid suspensions by filtration with membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/30—Polyalkenyl halides
    • B01D71/32—Polyalkenyl halides containing fluorine atoms
    • B01D71/36—Polytetrafluoroethene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0414—Surface modifiers, e.g. comprising ion exchange groups
    • B01D2239/0428—Rendering the filter material hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/38—Hydrophobic membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA2017/01732A 2014-10-09 2017-03-09 Method and device for separating immiscible liquids to effectively isolate at least one of the liquids ZA201701732B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462062134P 2014-10-09 2014-10-09
PCT/US2015/054985 WO2016057950A1 (en) 2014-10-09 2015-10-09 Method and device for separating immiscible liquids to effectively isolate at least one of the liquids

Publications (1)

Publication Number Publication Date
ZA201701732B true ZA201701732B (en) 2018-08-29

Family

ID=55653870

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2017/01732A ZA201701732B (en) 2014-10-09 2017-03-09 Method and device for separating immiscible liquids to effectively isolate at least one of the liquids

Country Status (14)

Country Link
US (2) US10118173B2 (en)
EP (1) EP3204148B1 (en)
JP (1) JP6668336B2 (en)
KR (1) KR20170066540A (en)
CN (1) CN106999850B (en)
AU (1) AU2015330688B2 (en)
BR (1) BR112017005038B1 (en)
CA (1) CA2960721C (en)
MX (1) MX2017004354A (en)
RU (1) RU2690346C2 (en)
SA (1) SA517381238B1 (en)
SG (1) SG11201701974XA (en)
WO (1) WO2016057950A1 (en)
ZA (1) ZA201701732B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108203514B (en) * 2016-12-16 2022-11-22 漂莱特（中国）有限公司 Method for producing uniform polymer beads by vibro-jet using superhydrophobic membranes
DE102017105600A1 (en) * 2017-03-16 2018-09-20 Bruker Daltonik Gmbh Separation of drop liquid and enclosed sedimented material
US11422082B2 (en) * 2018-01-03 2022-08-23 Conopco, Inc. Method for demonstrating cleansing efficacy
CN108548758B (en) * 2018-04-09 2020-09-15 上海海事大学 Method and device for rapidly detecting failure degree of cooling liquid
WO2020100039A1 (en) * 2018-11-13 2020-05-22 National Research Council Of Canada World-to-chip automated interface for centrifugal microfluidic platforms
WO2021102105A1 (en) * 2019-11-19 2021-05-27 University Of Cincinnati Devices and methods for concentration of analytes
US20210215591A1 (en) * 2020-01-13 2021-07-15 Fluent Biosciences Inc. Devices for generating monodisperse droplets from a bulk liquid
CN113230918B (en) * 2021-03-31 2022-05-10 厦门大学 Efficient low-energy-consumption membrane emulsification system and method

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880739A (en) * 1973-01-04 1975-04-29 Mobil Oil Corp Enzyme catalyzed oxidations of hydrocarbons
US4414280A (en) * 1980-08-08 1983-11-08 E. I. Du Pont De Nemours And Company Membranes and composites from fluoropolymer solutions
US4826494A (en) * 1984-11-09 1989-05-02 Stryker Corporation Vacuum wound drainage system
DK228686A (en) * 1985-05-21 1986-11-22 Technicon Instr HEAD-SHAPED APPLIANCE CONTAINING AT LEAST TWO INGRATIBLE LIQUIDS FOR SELECTIVE LIQUID SUPPLY TO AN ANALYZING INSTRUMENT
US4780211A (en) * 1986-11-07 1988-10-25 Desalination Systems, Inc. Method of dewatering using PTFE membrane
US4747959A (en) 1987-04-13 1988-05-31 Polysar Limited Analytical method and apparatus for characterizing latexes
US4971912A (en) * 1987-07-14 1990-11-20 Technicon Instruments Corporation Apparatus and method for the separation of immiscible liquids
JP2547354B2 (en) * 1990-06-18 1996-10-23 迪郎 芝崎 Method and apparatus for capturing sample having viscosity
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
US6090592A (en) 1994-08-03 2000-07-18 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid on supports
DE69530072T2 (en) 1994-12-08 2004-03-04 Molecular Dynamics, Sunnyvale FLUORESCENT IMAGING SYSTEM USING A LENS WITH MACRO SCANNING
US5528050A (en) 1995-07-24 1996-06-18 Molecular Dynamics, Inc. Compact scan head with multiple scanning modalities
JP3322595B2 (en) * 1996-03-28 2002-09-09 テルモ株式会社 Filter device and method for separating / collecting biological microstructure
US6117394A (en) 1996-04-10 2000-09-12 Smith; James C. Membrane filtered pipette tip
US5874004A (en) 1996-06-19 1999-02-23 Sheila H. Dewitt Phase separation filter device
US20030134035A1 (en) * 1997-03-20 2003-07-17 Unisearch Limited, A.C.N. 000 263 025 Hydrophobic films
JP2001517948A (en) 1997-04-01 2001-10-09 グラクソ、グループ、リミテッド Nucleic acid sequencing
US5851491A (en) 1997-06-13 1998-12-22 Labcon, North America Pipette tip and filter for accurate sampling and prevention of contamination
US6045757A (en) 1997-06-30 2000-04-04 Rainin Instrument Co., Inc. Membrane filter pipette tip
US6086768A (en) 1998-09-08 2000-07-11 Porocrit L.L.C. Method for demulsification of emulsions containing dense gas and liquid and a surfactant
AR021833A1 (en) 1998-09-30 2002-08-07 Applied Research Systems METHODS OF AMPLIFICATION AND SEQUENCING OF NUCLEIC ACID
US6565727B1 (en) 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
JP2003509232A (en) * 1999-09-17 2003-03-11 ミリポール・コーポレイシヨン Patterned porous structure
US20030098121A1 (en) 1999-11-17 2003-05-29 Wilson Moya Patterned porous structures
AU2001259113A1 (en) 2000-04-21 2001-11-07 Transgenomic, Inc. Apparatus and method for separating and purifying polynucleotides
US20030064366A1 (en) 2000-07-07 2003-04-03 Susan Hardin Real-time sequence determination
US8529743B2 (en) 2000-07-25 2013-09-10 The Regents Of The University Of California Electrowetting-driven micropumping
US6773566B2 (en) 2000-08-31 2004-08-10 Nanolytics, Inc. Electrostatic actuators for microfluidics and methods for using same
WO2002044425A2 (en) 2000-12-01 2002-06-06 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
AR031640A1 (en) 2000-12-08 2003-09-24 Applied Research Systems ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT
WO2002080822A2 (en) 2001-04-04 2002-10-17 Arradial, Inc. System and method for dispensing liquids
CA2472029C (en) 2001-11-26 2014-04-15 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
US6814859B2 (en) * 2002-02-13 2004-11-09 Nanostream, Inc. Frit material and bonding method for microfluidic separation devices
US20040002090A1 (en) 2002-03-05 2004-01-01 Pascal Mayer Methods for detecting genome-wide sequence variations associated with a phenotype
CN1382969A (en) * 2002-04-09 2002-12-04 中国科学院生态环境研究中心 In-situ sampler based on membane extraction technique for pollutants in natural water
FR2841063B1 (en) 2002-06-18 2004-09-17 Commissariat Energie Atomique DEVICE FOR DISPLACING SMALL VOLUMES OF LIQUID ALONG A MICRO-CATENARY BY ELECTROSTATIC FORCES
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
AU2003282741A1 (en) * 2002-10-07 2004-05-04 Marligen Biosciences, Inc. Extraction of dna from biological samples
US7547380B2 (en) 2003-01-13 2009-06-16 North Carolina State University Droplet transportation devices and methods having a fluid surface
EP1491258B1 (en) 2003-06-24 2008-12-03 Millipore Corporation Multifunctional vacuum manifold
AU2004283721B2 (en) 2003-10-24 2009-08-13 Adhesives Research, Inc. Rapidly disintegrating film
CN100478075C (en) 2003-11-17 2009-04-15 皇家飞利浦电子股份有限公司 System for manipulation of a body of fluid
EP3175914A1 (en) 2004-01-07 2017-06-07 Illumina Cambridge Limited Improvements in or relating to molecular arrays
FR2866493B1 (en) 2004-02-16 2010-08-20 Commissariat Energie Atomique DEVICE FOR CONTROLLING THE DISPLACEMENT OF A DROP BETWEEN TWO OR MORE SOLID SUBSTRATES
EP1730516A1 (en) 2004-03-30 2006-12-13 Pfizer Products Incorporated Method and device for evaluation of pharmaceutical compositions
FR2872715B1 (en) 2004-07-08 2006-11-17 Commissariat Energie Atomique MICROREACTOR DROP
FR2872809B1 (en) 2004-07-09 2006-09-15 Commissariat Energie Atomique METHOD OF ADDRESSING ELECTRODES
JP2006058031A (en) 2004-08-17 2006-03-02 Hitachi High-Technologies Corp Chemical analyzer
WO2006044078A2 (en) 2004-09-17 2006-04-27 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
US7458661B2 (en) 2005-01-25 2008-12-02 The Regents Of The University Of California Method and apparatus for promoting the complete transfer of liquid drops from a nozzle
WO2006081558A2 (en) 2005-01-28 2006-08-03 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
AU2006220816A1 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
GB0514936D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Preparation of templates for nucleic acid sequencing
US20070023292A1 (en) 2005-07-26 2007-02-01 The Regents Of The University Of California Small object moving on printed circuit board
US7405281B2 (en) 2005-09-29 2008-07-29 Pacific Biosciences Of California, Inc. Fluorescent nucleotide analogs and uses therefor
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
US7329860B2 (en) 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
EP1984738A2 (en) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
WO2007107710A1 (en) 2006-03-17 2007-09-27 Solexa Limited Isothermal methods for creating clonal single molecule arrays
CA2648149A1 (en) 2006-03-31 2007-11-01 Solexa, Inc. Systems and devices for sequence by synthesis analysis
US8492168B2 (en) 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
WO2010027894A2 (en) 2008-08-27 2010-03-11 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US7851184B2 (en) 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
DE602006018794D1 (en) 2006-04-18 2011-01-20 Advanced Liquid Logic Inc BIOCHEMISTRY ON THE DREAM BASE
WO2007143133A2 (en) 2006-05-31 2007-12-13 Micropore Plastics, Inc. Modular filter assembly
CN101490562B (en) 2006-07-10 2012-12-19 株式会社日立高新技术 Liquid transfer device
JP2008039434A (en) * 2006-08-01 2008-02-21 Ckd Corp Separator and automatic storring system using the same
CN101528824B (en) 2006-08-18 2012-05-09 珀雷克斯公司 Sintered polymeric materials and applications thereof
WO2008042067A2 (en) 2006-09-28 2008-04-10 Illumina, Inc. Compositions and methods for nucleotide sequencing
AU2007309504B2 (en) 2006-10-23 2012-09-13 Pacific Biosciences Of California, Inc. Polymerase enzymes and reagents for enhanced nucleic acid sequencing
WO2008055256A2 (en) 2006-11-02 2008-05-08 The Regents Of The University Of California Method and apparatus for real-time feedback control of electrical manipulation of droplets on chip
WO2008063135A1 (en) * 2006-11-24 2008-05-29 Agency For Science, Technology And Research Apparatus for processing a sample in a liquid droplet and method of using the same
KR101431778B1 (en) 2007-02-09 2014-08-20 어드밴스드 리퀴드 로직, 아이엔씨. Droplet actuator devices and methods employing magnetic beads
BRMU8700248Y1 (en) 2007-02-12 2016-12-20 José Carlos Lapenna constructive arrangement applied to a sample collector for parasitological examination of feces
WO2008101194A2 (en) 2007-02-15 2008-08-21 Advanced Liquid Logic, Inc. Capacitance detection in a droplet actuator
CN101678250B (en) 2007-03-02 2013-04-24 史密夫及内修公开有限公司 Apparatus and method for filter cleaning by ultrasound, backwashing and filter movement during the filtration of biological samples
US8093062B2 (en) 2007-03-22 2012-01-10 Theodore Winger Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil
US20080283414A1 (en) 2007-05-17 2008-11-20 Monroe Charles W Electrowetting devices
CN101679932A (en) 2007-06-27 2010-03-24 数字化生物系统 Digital microfluidics based apparatus for heat-exchanging chemical processes
US20110303542A1 (en) 2007-08-08 2011-12-15 Advanced Liquid Logic, Inc. Use of Additives for Enhancing Droplet Operations
US9487822B2 (en) 2008-03-19 2016-11-08 Fluidigm Corporation Method and apparatus for determining copy number variation using digital PCR
US8039817B2 (en) 2008-05-05 2011-10-18 Illumina, Inc. Compensator for multiple surface imaging
US8093064B2 (en) 2008-05-15 2012-01-10 The Regents Of The University Of California Method for using magnetic particles in droplet microfluidics
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
WO2010120977A1 (en) 2009-04-16 2010-10-21 Porex Corporation Ground porous sintered materials and applications thereof
WO2011002957A2 (en) 2009-07-01 2011-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
JP2011095157A (en) * 2009-10-30 2011-05-12 Tdk Corp Collection instrument and method for using the same
EP3072968A1 (en) 2010-02-25 2016-09-28 Advanced Liquid Logic, Inc. Method of making nucleic acid libraries
DE202011003570U1 (en) 2010-03-06 2012-01-30 Illumina, Inc. Systems and apparatus for detecting optical signals from a sample
JP2011189270A (en) * 2010-03-15 2011-09-29 Sumitomo Bakelite Co Ltd Microplate and separation method
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US9190736B1 (en) * 2011-01-17 2015-11-17 Sandia Corporation Fabrication of small-scale structures with non-planar features
CA2825008C (en) * 2011-01-19 2020-10-13 President And Fellows Of Harvard College Slippery surfaces with high pressure stability, optical transparency, and self-healing characteristics
US8901043B2 (en) 2011-07-06 2014-12-02 Advanced Liquid Logic, Inc. Systems for and methods of hybrid pyrosequencing
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US10343085B2 (en) * 2011-10-14 2019-07-09 W. L. Gore & Associates, Inc. Multilayer porous composite
WO2013117595A2 (en) 2012-02-07 2013-08-15 Illumina Cambridge Limited Targeted enrichment and amplification of nucleic acids on a support
NO2694769T3 (en) 2012-03-06 2018-03-03
EP4219012A1 (en) 2012-04-03 2023-08-02 Illumina, Inc. Method of imaging a substrate comprising fluorescent features and use of the method in nucleic acid sequencing
WO2013165594A1 (en) 2012-04-30 2013-11-07 Life Technologies Corporation Modules and calibration method for a robotic polynucleotide sample preparation system
JP2015519900A (en) 2012-05-21 2015-07-16 フリューダイム・コーポレイション Single particle analysis method and single particle isolation method for particle population
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
EP2692402A1 (en) * 2012-07-31 2014-02-05 Biotage AB Phase separation element and phase separation device
US20150276568A1 (en) 2012-10-01 2015-10-01 University Of Oslo Micro-scale liquid-liquid-liquid extraction
US9388945B2 (en) 2013-02-01 2016-07-12 Bio-Rad Laboratories, Inc. System for emulsion aspiration
US20140272996A1 (en) 2013-03-15 2014-09-18 Bio-Rad Laboratories, Inc. Droplet generator with collection tube
RU2525936C1 (en) * 2013-07-09 2014-08-20 Федеральное государственное бюджетное учреждение высшего профессионального образования "Челябинская государственная агроинженерная академия" Method of filtering solutions and suspensions

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