ZA201400231B - Treatment of excessive menstrual bleeding associated with uterine fibroids - Google Patents
Treatment of excessive menstrual bleeding associated with uterine fibroidsInfo
- Publication number
- ZA201400231B ZA201400231B ZA2014/00231A ZA201400231A ZA201400231B ZA 201400231 B ZA201400231 B ZA 201400231B ZA 2014/00231 A ZA2014/00231 A ZA 2014/00231A ZA 201400231 A ZA201400231 A ZA 201400231A ZA 201400231 B ZA201400231 B ZA 201400231B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- uterine fibroids
- menstrual bleeding
- bleeding associated
- excessive menstrual
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506704P | 2011-07-12 | 2011-07-12 | |
| EP11173630A EP2545922A1 (en) | 2011-07-12 | 2011-07-12 | Treatment of excessive menstrual bleeding associated with uterine fibroids |
| PCT/IB2012/053577 WO2013008202A1 (en) | 2011-07-12 | 2012-07-12 | Treatment of excessive menstrual bleeding associated with uterine fibroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201400231B true ZA201400231B (en) | 2014-10-29 |
Family
ID=44720552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2014/00231A ZA201400231B (en) | 2011-07-12 | 2014-01-10 | Treatment of excessive menstrual bleeding associated with uterine fibroids |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9168264B2 (en) |
| EP (2) | EP2545922A1 (en) |
| JP (1) | JP2014520840A (en) |
| KR (1) | KR101932789B1 (en) |
| CN (1) | CN103648503A (en) |
| AU (1) | AU2012282061B2 (en) |
| BR (1) | BR112014000650A2 (en) |
| CA (1) | CA2836346A1 (en) |
| CO (1) | CO6870034A2 (en) |
| EA (1) | EA026721B1 (en) |
| GE (1) | GEP20166430B (en) |
| HU (1) | HUE037294T2 (en) |
| IL (1) | IL229515B (en) |
| MX (1) | MX2014000474A (en) |
| MY (1) | MY165571A (en) |
| WO (1) | WO2013008202A1 (en) |
| ZA (1) | ZA201400231B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2545922A1 (en) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Treatment of excessive menstrual bleeding associated with uterine fibroids |
| WO2014140217A1 (en) * | 2013-03-14 | 2014-09-18 | Laboratoire Hra-Pharma | Method for scheduling ovulation |
| EP3394078A4 (en) | 2015-12-23 | 2019-11-27 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| CA3009525A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| US11110103B2 (en) | 2015-12-23 | 2021-09-07 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| CA3015781A1 (en) * | 2016-02-24 | 2017-08-31 | Eastern Virginia Medical School | An improved formulation of long-acting levonorgestrel butanoate injectable depot suspension |
| PL3523315T3 (en) | 2016-10-07 | 2021-10-18 | Oric Pharmaceuticals, Inc. | Inhibitor of glucocorticoid receptor |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4954490A (en) | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
| AU714959B2 (en) * | 1995-02-02 | 2000-01-13 | Schering Aktiengesellschaft | Progesterone antagonists for the production of pharmaceutical agents for the treatment of dysfunctional uterine bleeding |
| US5929262A (en) | 1995-03-30 | 1999-07-27 | The United States Of America As Represented By The Department Of Health And Human Services | Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates |
| US6900193B1 (en) * | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| ES2212912B1 (en) | 2003-01-22 | 2005-10-01 | Crystal Pharma, S.A. | PROCEDURE FOR OBTAINING 17ALFA-ACETOXI-11BETA- (4-N, N-DIMETHYLAMINEPHENYL) -19-NORPREGNA-4,9-DIEN-3,20-DIONA. |
| WO2004078709A2 (en) | 2003-02-28 | 2004-09-16 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | METHOD FOR PREPARING 17 α-ACETOXY-11β-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES THEREOF, AND METHODS FOR THE PREPARATION OF SUCH INTERMEDIATES |
| DE602005026290D1 (en) | 2004-07-09 | 2011-03-24 | Population Council Inc | COMPOSITIONS OF DELAYED RELEASE WITH PROGESTERONE RECEPTOR MODULATORS |
| BRPI0610438A2 (en) * | 2005-04-28 | 2012-10-23 | Wyeth Corp | pharmaceutical composition, capsule, pharmaceutical composition and process for preparing a composition |
| CN101316595A (en) | 2005-09-29 | 2008-12-03 | 利普生物药剂公司 | Formulations with improved bioavailability, comprising a steroid derivative and a polyglycolysed glyceride |
| WO2007103510A2 (en) | 2006-03-08 | 2007-09-13 | Danco Laboratories Llc | Methods, dosing regimens & medications using anti-progestational agents for the treatment of disorders |
| MX2009006912A (en) | 2006-12-28 | 2009-08-12 | Repros Therapeutics Inc | Methods and formulations for improved bioavalability of antiprogestins. |
| ES2575554T3 (en) * | 2007-04-20 | 2016-06-29 | Preglem S.A. | Selective progesterone modulators in the treatment of uterine hemorrhage |
| US20090118253A1 (en) * | 2007-11-05 | 2009-05-07 | Repros Therapeutics Inc. | Compositions and methods for treating dysfunctional uterine bleeding |
| US8299050B2 (en) * | 2008-01-29 | 2012-10-30 | Laboratoire Hra-Pharma | Method for treating uterine fibroids |
| US7998994B2 (en) | 2008-06-18 | 2011-08-16 | Lexicon Pharmaceuticals, Inc. | Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol and methods of their use |
| DE202011110355U1 (en) * | 2011-03-09 | 2014-01-15 | Arstat, Inc. | Treatment of uterine fibroids by intravaginal administration of a low dose of a selective progesterone receptor modulator, an antigestagens or an antigestagen agent |
| EP2545922A1 (en) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Treatment of excessive menstrual bleeding associated with uterine fibroids |
-
2011
- 2011-07-12 EP EP11173630A patent/EP2545922A1/en not_active Withdrawn
-
2012
- 2012-07-12 CN CN201280033651.XA patent/CN103648503A/en active Pending
- 2012-07-12 EP EP12755904.5A patent/EP2731613B1/en not_active Revoked
- 2012-07-12 JP JP2014519684A patent/JP2014520840A/en active Pending
- 2012-07-12 EA EA201490209A patent/EA026721B1/en not_active IP Right Cessation
- 2012-07-12 CA CA2836346A patent/CA2836346A1/en not_active Abandoned
- 2012-07-12 WO PCT/IB2012/053577 patent/WO2013008202A1/en active Application Filing
- 2012-07-12 GE GEAP201213383A patent/GEP20166430B/en unknown
- 2012-07-12 AU AU2012282061A patent/AU2012282061B2/en not_active Ceased
- 2012-07-12 BR BR112014000650-4A patent/BR112014000650A2/en not_active Application Discontinuation
- 2012-07-12 HU HUE12755904A patent/HUE037294T2/en unknown
- 2012-07-12 MX MX2014000474A patent/MX2014000474A/en unknown
- 2012-07-12 US US14/131,857 patent/US9168264B2/en not_active Expired - Fee Related
- 2012-07-12 KR KR1020137034680A patent/KR101932789B1/en active IP Right Grant
- 2012-07-12 MY MYPI2013004119A patent/MY165571A/en unknown
-
2013
- 2013-11-20 IL IL229515A patent/IL229515B/en active IP Right Grant
-
2014
- 2014-01-10 ZA ZA2014/00231A patent/ZA201400231B/en unknown
- 2014-01-30 CO CO14019457A patent/CO6870034A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA201490209A1 (en) | 2014-06-30 |
| IL229515A0 (en) | 2014-01-30 |
| CO6870034A2 (en) | 2014-02-20 |
| HUE037294T2 (en) | 2018-09-28 |
| US9168264B2 (en) | 2015-10-27 |
| KR101932789B1 (en) | 2018-12-27 |
| EA026721B1 (en) | 2017-05-31 |
| JP2014520840A (en) | 2014-08-25 |
| MY165571A (en) | 2018-04-05 |
| EP2731613A1 (en) | 2014-05-21 |
| EP2545922A1 (en) | 2013-01-16 |
| KR20140050614A (en) | 2014-04-29 |
| MX2014000474A (en) | 2014-02-20 |
| NZ619478A (en) | 2015-12-24 |
| AU2012282061A1 (en) | 2014-01-23 |
| US20140148419A1 (en) | 2014-05-29 |
| WO2013008202A1 (en) | 2013-01-17 |
| BR112014000650A2 (en) | 2020-10-27 |
| CN103648503A (en) | 2014-03-19 |
| IL229515B (en) | 2018-01-31 |
| EP2731613B1 (en) | 2017-08-30 |
| GEP20166430B (en) | 2016-02-10 |
| AU2012282061B2 (en) | 2016-11-10 |
| CA2836346A1 (en) | 2013-01-17 |
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