ZA201101824B - Lcms technology and its uses - Google Patents

Lcms technology and its uses

Info

Publication number
ZA201101824B
ZA201101824B ZA2011/01824A ZA201101824A ZA201101824B ZA 201101824 B ZA201101824 B ZA 201101824B ZA 2011/01824 A ZA2011/01824 A ZA 2011/01824A ZA 201101824 A ZA201101824 A ZA 201101824A ZA 201101824 B ZA201101824 B ZA 201101824B
Authority
ZA
South Africa
Prior art keywords
lcms technology
lcms
technology
Prior art date
Application number
ZA2011/01824A
Inventor
Els Cecile Antoinette Carola Maria Van
Jong Adrianus Josephus Maria De
Ernst Christiaan Soethout
Hugo Derk Meiring
Original Assignee
De Staat Der Nederlanden Vert Door De Mini Van Vws
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Staat Der Nederlanden Vert Door De Mini Van Vws filed Critical De Staat Der Nederlanden Vert Door De Mini Van Vws
Publication of ZA201101824B publication Critical patent/ZA201101824B/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724Nebulising, aerosol formation or ionisation
    • G01N30/7266Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/461Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6034Construction of the column joining multiple columns
    • G01N30/6039Construction of the column joining multiple columns in series
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165Electrospray ionisation
    • H01J49/167Capillaries and nozzles specially adapted therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • G01N2030/562Packing methods or coating methods packing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • G01N2030/562Packing methods or coating methods packing
    • G01N2030/565Packing methods or coating methods packing slurry packing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA2011/01824A 2008-09-09 2011-03-09 Lcms technology and its uses ZA201101824B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08163987 2008-09-09
PCT/NL2009/050539 WO2010030178A1 (en) 2008-09-09 2009-09-09 Lcms technology and its uses

Publications (1)

Publication Number Publication Date
ZA201101824B true ZA201101824B (en) 2011-11-30

Family

ID=40627150

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/01824A ZA201101824B (en) 2008-09-09 2011-03-09 Lcms technology and its uses

Country Status (14)

Country Link
US (1) US20110186731A1 (en)
EP (1) EP2324347A1 (en)
JP (1) JP2012502296A (en)
KR (1) KR20110084182A (en)
CN (1) CN102216768A (en)
AU (1) AU2009292304A1 (en)
BR (1) BRPI0918460A2 (en)
CA (1) CA2736479A1 (en)
IL (1) IL211657A0 (en)
MX (1) MX2011002567A (en)
NZ (1) NZ591617A (en)
RU (1) RU2011113852A (en)
WO (1) WO2010030178A1 (en)
ZA (1) ZA201101824B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9504936B2 (en) * 2010-04-05 2016-11-29 Purdue Research Foundation Method of packing chromatographic columns
CN102621259B (en) * 2011-03-24 2014-08-20 苏州汇通色谱分离纯化有限公司 Capillary parabolic shape capillary liquid chromatography preparative column
CN102565246A (en) * 2011-11-23 2012-07-11 福建中烟工业有限责任公司 Valve switching method for improving performance of gas chromatography heart cutting technology
JP2015524418A (en) 2012-07-27 2015-08-24 アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル CD147 as a receptor for pili-mediated adhesion of Neisseria meningitidis to vascular endothelial cells
WO2016098757A1 (en) * 2014-12-15 2016-06-23 積水メディカル株式会社 Method for detecting amino acids or acylcarnitine
CN105218671A (en) * 2015-09-29 2016-01-06 李艳华 The preparation method of the full humanized antibody of a kind of infectious disease pathogens
GB201701986D0 (en) 2017-02-07 2017-03-22 Thermo Fisher Scient (Bremen) Gmbh n
CN114464521B (en) * 2022-02-17 2024-04-19 河北医科大学 Capillary needle and preparation method thereof
CN115356425A (en) * 2022-07-27 2022-11-18 上海奥浦迈生物科技股份有限公司 NanoHPLC-Titer system applied to culture medium supernatant albumin quantification

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679255A (en) * 1992-06-22 1997-10-21 The Dow Chemical Company Microcolumns for chromatography and method for making same
US5389221A (en) * 1993-03-09 1995-02-14 The University Of North Carolina At Chapel Hill Two dimensional separation system
US5788166A (en) * 1996-08-27 1998-08-04 Cornell Research Foundation, Inc. Electrospray ionization source and method of using the same
CA2317495C (en) * 1998-01-12 2004-11-09 F. William Collins A process for the isolation, recovery and purification of non-polar extractives
NL1016034C2 (en) * 2000-08-03 2002-02-08 Tno Method and system for identifying and quantifying chemical components of a mixture of materials to be investigated.
AU2002243385C1 (en) * 2000-10-23 2008-07-24 Genetics Institute, Llc Acid-labile isotope-coded extractant (ALICE) in mass spectrometric analysis
US6395183B1 (en) * 2001-01-24 2002-05-28 New Objectives, Inc. Method for packing capillary columns with particulate materials
US6989129B2 (en) * 2001-04-05 2006-01-24 The President And Fellows Of Harvard College Automated capillary liquid chromatography small volume analysis system
US7976779B2 (en) * 2002-06-26 2011-07-12 California Institute Of Technology Integrated LC-ESI on a chip
JP2004101477A (en) * 2002-09-12 2004-04-02 Yoshio Yamauchi Two-dimensional high performance liquid chromatographic device and protein analyzer using the same
US6909091B2 (en) * 2003-05-30 2005-06-21 Nanosep Ab Separation and analysis of sample components
US7087895B1 (en) * 2003-06-07 2006-08-08 Musc Foundation For Research Development Electrospray ionization using pointed fibers
US7015466B2 (en) * 2003-07-24 2006-03-21 Purdue Research Foundation Electrosonic spray ionization method and device for the atmospheric ionization of molecules
JP4613002B2 (en) * 2003-10-29 2011-01-12 株式会社日立ハイテクノロジーズ Method for manufacturing column-integrated chip for electrospray
US20060060769A1 (en) * 2004-09-21 2006-03-23 Predicant Biosciences, Inc. Electrospray apparatus with an integrated electrode
US7763848B2 (en) * 2005-01-18 2010-07-27 Phoenix S&T, Inc. Apparatus and method for controlling an electrostatically induced liquid spray
WO2006078859A2 (en) * 2005-01-20 2006-07-27 Waters Investments Limited Methods for separating compounds
GB0609253D0 (en) * 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer
US7758754B2 (en) * 2007-01-09 2010-07-20 Membrane Technology And Research, Inc Pervaporation process and assembly
WO2008130735A1 (en) * 2007-02-26 2008-10-30 Wisconsin Alumni Research Foundation Surface plasmon resonance compatible carbon thin films

Also Published As

Publication number Publication date
JP2012502296A (en) 2012-01-26
US20110186731A1 (en) 2011-08-04
MX2011002567A (en) 2011-09-27
IL211657A0 (en) 2011-05-31
NZ591617A (en) 2012-11-30
RU2011113852A (en) 2012-10-20
AU2009292304A2 (en) 2011-05-12
CN102216768A (en) 2011-10-12
KR20110084182A (en) 2011-07-21
AU2009292304A1 (en) 2010-03-18
WO2010030178A1 (en) 2010-03-18
BRPI0918460A2 (en) 2015-11-24
EP2324347A1 (en) 2011-05-25
CA2736479A1 (en) 2010-03-18

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