ZA201004258B - Hydrosol composition - Google Patents
Hydrosol composition Download PDFInfo
- Publication number
- ZA201004258B ZA201004258B ZA2010/04258A ZA201004258A ZA201004258B ZA 201004258 B ZA201004258 B ZA 201004258B ZA 2010/04258 A ZA2010/04258 A ZA 2010/04258A ZA 201004258 A ZA201004258 A ZA 201004258A ZA 201004258 B ZA201004258 B ZA 201004258B
- Authority
- ZA
- South Africa
- Prior art keywords
- skin
- plant
- hydrosol
- pelargonium
- product
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 13
- 241000196324 Embryophyta Species 0.000 claims description 31
- 241000208181 Pelargonium Species 0.000 claims description 28
- 208000027418 Wounds and injury Diseases 0.000 claims description 21
- 238000011282 treatment Methods 0.000 claims description 21
- 206010052428 Wound Diseases 0.000 claims description 19
- 239000007921 spray Substances 0.000 claims description 17
- 239000000126 substance Substances 0.000 claims description 17
- 238000001256 steam distillation Methods 0.000 claims description 14
- 230000003796 beauty Effects 0.000 claims description 12
- 230000002708 enhancing effect Effects 0.000 claims description 10
- 239000006071 cream Substances 0.000 claims description 9
- 208000015181 infectious disease Diseases 0.000 claims description 9
- 239000000341 volatile oil Substances 0.000 claims description 9
- 208000014617 hemorrhoid Diseases 0.000 claims description 8
- 208000018962 mouth sore Diseases 0.000 claims description 8
- 230000037307 sensitive skin Effects 0.000 claims description 8
- 206010025282 Lymphoedema Diseases 0.000 claims description 7
- 230000000973 chemotherapeutic effect Effects 0.000 claims description 7
- 239000000499 gel Substances 0.000 claims description 7
- 230000004054 inflammatory process Effects 0.000 claims description 7
- 208000002502 lymphedema Diseases 0.000 claims description 7
- 238000001959 radiotherapy Methods 0.000 claims description 7
- 208000029549 Muscle injury Diseases 0.000 claims description 6
- 230000001580 bacterial effect Effects 0.000 claims description 6
- 229920006395 saturated elastomer Polymers 0.000 claims description 6
- 230000008470 skin growth Effects 0.000 claims description 6
- 206010040872 skin infection Diseases 0.000 claims description 6
- 238000001356 surgical procedure Methods 0.000 claims description 6
- 206010061218 Inflammation Diseases 0.000 claims description 5
- 238000010521 absorption reaction Methods 0.000 claims description 5
- 230000035515 penetration Effects 0.000 claims description 5
- 230000002265 prevention Effects 0.000 claims description 5
- 206010040882 skin lesion Diseases 0.000 claims description 5
- 231100000444 skin lesion Toxicity 0.000 claims description 5
- 230000001225 therapeutic effect Effects 0.000 claims description 5
- 206010017543 Fungal skin infection Diseases 0.000 claims description 4
- 239000006210 lotion Substances 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 239000007933 dermal patch Substances 0.000 claims description 3
- 230000001050 lubricating effect Effects 0.000 claims description 3
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 6
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000000284 extract Substances 0.000 description 5
- 239000003349 gelling agent Substances 0.000 description 5
- 239000010409 thin film Substances 0.000 description 5
- 230000000740 bleeding effect Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 description 3
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 description 3
- 239000005792 Geraniol Substances 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 description 3
- 235000000484 citronellol Nutrition 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 229940113087 geraniol Drugs 0.000 description 3
- 230000002757 inflammatory effect Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 239000011505 plaster Substances 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- DZNVIZQPWLDQHI-UHFFFAOYSA-N Citronellyl formate Chemical compound O=COCCC(C)CCC=C(C)C DZNVIZQPWLDQHI-UHFFFAOYSA-N 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 description 2
- 206010067152 Oral herpes Diseases 0.000 description 2
- 241001138371 Pelargonium capitatum Species 0.000 description 2
- 206010053262 Skin swelling Diseases 0.000 description 2
- UAHWPYUMFXYFJY-UHFFFAOYSA-N beta-myrcene Chemical compound CC(C)=CCCC(=C)C=C UAHWPYUMFXYFJY-UHFFFAOYSA-N 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- BRHDDEIRQPDPMG-UHFFFAOYSA-N trans-furanoid linalool oxide Natural products CC(C)(O)C1CCC(C)(C=C)O1 BRHDDEIRQPDPMG-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 description 1
- NFLGAXVYCFJBMK-IUCAKERBSA-N (-)-isomenthone Chemical compound CC(C)[C@@H]1CC[C@H](C)CC1=O NFLGAXVYCFJBMK-IUCAKERBSA-N 0.000 description 1
- BCTBAGTXFYWYMW-UHFFFAOYSA-N (3-R!)-2,2,6t-Trimethyl-6c-vinyl-tetrahydro-pyran-3r-ol Natural products CC1(C)OC(C)(C=C)CCC1O BCTBAGTXFYWYMW-UHFFFAOYSA-N 0.000 description 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- KSKXSFZGARKWOW-GQCTYLIASA-N (3e)-6-methylhepta-3,5-dien-2-one Chemical compound CC(C)=C\C=C\C(C)=O KSKXSFZGARKWOW-GQCTYLIASA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- WUOACPNHFRMFPN-SECBINFHSA-N (S)-(-)-alpha-terpineol Chemical compound CC1=CC[C@@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-SECBINFHSA-N 0.000 description 1
- BRHDDEIRQPDPMG-PSASIEDQSA-N (±)-cis-Linalyl oxide Chemical compound CC(C)(O)[C@H]1CC[C@@](C)(C=C)O1 BRHDDEIRQPDPMG-PSASIEDQSA-N 0.000 description 1
- IFJYSOWCCJPUJS-UHFFFAOYSA-N 1,4-dimethyl-7-propan-2-yl-1,2,3,4,5,8-hexahydroazulene Chemical compound C1C(C(C)C)=CCC(C)C2=C1C(C)CC2 IFJYSOWCCJPUJS-UHFFFAOYSA-N 0.000 description 1
- VVUMWAHNKOLVSN-UHFFFAOYSA-N 2-(4-ethoxyanilino)-n-propylpropanamide Chemical compound CCCNC(=O)C(C)NC1=CC=C(OCC)C=C1 VVUMWAHNKOLVSN-UHFFFAOYSA-N 0.000 description 1
- YDDGKXBLOXEEMN-IABMMNSOSA-L Chicoric acid Natural products C1=C(O)C(O)=CC=C1\C=C\C(=O)O[C@@H](C([O-])=O)[C@H](C([O-])=O)OC(=O)\C=C\C1=CC=C(O)C(O)=C1 YDDGKXBLOXEEMN-IABMMNSOSA-L 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000208152 Geranium Species 0.000 description 1
- 208000004898 Herpes Labialis Diseases 0.000 description 1
- 206010023232 Joint swelling Diseases 0.000 description 1
- 235000017927 Pelargonium graveolens Nutrition 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000010040 Sprains and Strains Diseases 0.000 description 1
- 208000002847 Surgical Wound Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- VYBREYKSZAROCT-UHFFFAOYSA-N alpha-myrcene Natural products CC(=C)CCCC(=C)C=C VYBREYKSZAROCT-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- FQMZVFJYMPNUCT-UHFFFAOYSA-N geraniol formate Natural products CC(C)=CCCC(C)=CCOC=O FQMZVFJYMPNUCT-UHFFFAOYSA-N 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000008131 herbal destillate Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000001819 mass spectrum Methods 0.000 description 1
- 229930007503 menthone Natural products 0.000 description 1
- KSKXSFZGARKWOW-UHFFFAOYSA-N methylheptadienone Natural products CC(C)=CC=CC(C)=O KSKXSFZGARKWOW-UHFFFAOYSA-N 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- BRHDDEIRQPDPMG-SCZZXKLOSA-N trans-furan linalool oxide Chemical compound CC(C)(O)[C@H]1CC[C@](C)(C=C)O1 BRHDDEIRQPDPMG-SCZZXKLOSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Description
/ | 2010/7 042568 ’ I
THIS INVENTION relates to the use of plant extracts in the manufacture of medicaments.
The invention is directed in particular to the use of an extract 5 ofa plant of the genus Pelargonium in the manufacture of a medicament : or preparation for use in the treatment of a disease or condition selected from haemorrhoids, mouth sores, surgical or other bleeding wounds, burns, muscle injuries, skin conditions resulting from radiotherapy, sensitive skin resulting from beauty treatment or beauty surgery, skin ~~ 10 lesions, skin growths, fungal and/or bacterial skin infections, inflammation and swelling caused by lymphedema. The extract may also be used in the prevention of infection, enhancing the effectiveness of chemotherapeutic treatment and enhancing absorption and penetration of therapeutic substances through the skin.
More specifically, in accordance with a first aspect of the invention, there is provided the use of a hydrosol produced by the steam distillation of a plant of the genus Pelargonium in the manufacture of a skin product for the treatment of haemorrhoids, mouth sores, wounds, burns, 2 muscle injuries, skin conditions caused by radiotherapy, skin conditions - caused by beauty surgery, sensitive skin caused by beauty treatment, skin lesions, skin growths, fungal skin infections, bacterial skin infections, inflammation caused by lymphedema; the prevention of infection; enhancing the effectiveness of chemotherapeutic treatment; or
: 2010/ 04258 enhancing absorption and penetration of therapeutic substances through the skin. :
The plant of the genus Pelargonium may be a plant of the species Pelargonium alveolens. The preferred variety of Pelargonium alveolens is the variety Bourbon. The plant of the species Pelargonium alveolens may thus be Pelargonium alveolens, variety Bourbon. ~The hydrosol may be produced by steam distillation of the leaves of the plant. In particular, the hydrosol may be the lower aqueous layer of a two phase distillate comprising an upper essential oil layer and a lower oil-saturated aqueous layer which is produced in the steam distillation process. oo
Pelargonium alveolens is also called rose geranium. The genus Pelargonium is one of the genera of the family Lamniaceae. [It is an important aspect of the invention that the plant extract is not produced by the addition of essential oils, by extraction with alcohol or by using any other synthetic substances. The products produced by such processes are known as hydrolats or floral waters. In contrast, the extract (or hydrosol) of the invention is a fully natural product which is obtained by steam distillation. 3 25 The hydrosol of the invention is ideal for application to the 3 skin because, unlike essential oils, it does not irritate the skin and can be : used for even the most sensitive skin.
The invention also provides a substance or composition for use in a method of treating a disease or condition selected from haemorrhoids, mouth sores, surgical or other bleeding wounds, burns,
2010/ 04238 ® muscle injuries, skin conditions resulting from radiotherapy, sensitive skin resulting from beauty treatment or beauty surgery, skin lesions, skin growths, fungal and/or bacterial skin infections, inflammation and swelling caused by lymphedema, the substance or composition comprising an extract of a plant of the genus Pelargolium.
Lymphedema commonly causes swollen ankles. oo More particularly, according to a second aspect of the invention, there is provided a substance or composition for use in the treatment of haemorrhoids, mouth sores, wounds, burns, muscle injuries, skin conditions caused by radiotherapy, skin conditions caused by beauty surgery, sensitive skin caused by beauty treatment, skin lesions, skin growths, fungal skin infections, bacterial skin infections, inflammation caused by lymphedema; the prevention of infection; | : enhancing the effectiveness of chemotherapeutic treatment; or enhancing absorption and penetration of therapeutic substances through the skin, the substance or composition comprising a hydrosol produced by the steam distillation of a plant of the genus Pelargonium.
The plant of the genus Pelargonium may be a plant of the species Pelargonium alveolens as hereinbefore described. The: hydrosol may be produced by steam distillation of the leaves of the plant as : hereinbefore described.
In particular, the hydrosol may be the lower oil-saturated aqueous layer of a two phase distillate comprising an upper essential oil layer and the lower layer.
}
The plant extract, or hydrosol, of the invention can be used in the form of a spray, a towelette or wipe, a face mask, a gel or cream, such as a water soluble cream, a massage lotion, a lubricating carrier cream, a skin patch or a bandage.
S N N
Thus, according to a third aspect of the invention, there is provided a product for use on the skin, the product being in a form selected from sprays, towelettes, wipes, face masks, gels, creams, massage lotions, lubricating carrier creams, skin patches and bandages and comprising a hydrosol produced by the steam distillation of a plant of the genus Pelargonium.
The plant of the genus Pelargonium may be a plant of the species Pelargonium alveolens. The hydrosol may be produced by steam distillation of the leaves of the plant. In particular the hydrosol may be the lower oil-saturated aqueous layer of a two phase distillate comprising an upper essential oil layer and the lower layer:
The plant of the species Pelargonium alveolens may be the variety Bourbon.
So The invention is now described, by way of example, with reference to the following examples.
Example 1 | : .
Analysis
Natural rose scented geranium hydrosol was analysed by gas ~~ 30 chromatography-mass spectrometry.
Co | £.2010/ 0425¢
Analysing conditions:
Agilent GC-MS (GC 6890N/MS5973) system operating under the following conditions; column: HP-Innowax (60m x 0.25mm id., 0.25pm film thickness) helium as carrier gas; Temperatures: injection port 250°C, column 60°C for 10 min, 4°C/min to 220°C for 10 min, 1°C/min to 240°C (total=80 min). Split ratio was adjusted to 200:1. The MS were taken at oo 70 eV. The mass range was from m/z 35 to 550. Data was recorded after a 7.5min lag phase. Component identifications were made by comparing their mass spectra and retention indices using commercial libraries and an in-house library. Relative percentage amounts were calculated from the
FID chromatogram. The results are set out below. | .
Active ingredients : myrcene (1.4%) trans-linalool oxide (5.7%) cis-linalool oxide (4.0%) menthone (3.0%) linalool (14.9%) 6-methyl-3,5-heptadien-2-one (1.0%) a-terpineol (2,5%) citronellol (19.2%) geraniol (25.6%) : : undetermined (3.0%) -
Total 80.3%
The geranium essential oil from which the hydrosol of the invention was derived was also analysed by gas chromatography-mass spectrometry andthe results are set out below.
Co . 2010/ 04258
Retention Time Retention index Compound Percentage of oil 14.62 1162 iso-menthone Aso 16.51 1225 citronellol 17.28 1252 geraniol 11.63 17.87 1273 citronellyl formate [13.49 18.64 1298 geranyl formate 22.70 | 1444 guaiadiene (6,9)
Analysed by SABS citronellol : geraniol 2.17
Example 2
Examples of the use of the extract of the invention are set out in Table 1.
Table ‘Medical.condition «| Composition. | Application 7 Bosal. (Restle vi i t 3 4 Wer =H ‘medicament, + ‘Medicament i| directions of use © a | . 1. External Hydrosol with | Tube. Apply directly to Immediate relief and haemorrhoids. gelling agent external haemorrhoids or carrier haemorroids twice a | disappeared cream. day until altogether over a heamorroids period of a day or disappear. two.
Neat hydrosol. | Patch or spray. | Apply directly to the | Haemorrhiods : affected area as disappeared often as needed. altogether over a short period. 2. Mouth sores and Hydrosol with | Tube. Apply directly to blisters (most mouth | gelling agent. mouth sore or blister sores are cold sores, (4-5 times per day also called fever or as frequently as blisters, oral Herpes needed) until : most commonly : symptom disappear. occurs outside the mouth on and around . the lips).
£.
E-2010/ 0425
Neat hydrosol | Spray. Spray on the Immediate relief. spray. affected area and leave for a few minutes. Repeat several times per day as needed. 3. Surgical wounds. | Hydrosol with | Prepacked Apply dressing on The hydrosol provided gelling agent. | hydrosol gel the wound and an immediate anti- wound dressing. | secure with inflammatory bandage or plaster. | treatment and
Leave for2 or 3 provided an days and repeat antibacterial action until wound is and a barrier to : | healed. further infection.
Neat hydrosol | Spray Spray a thin fim | Hydrosol kept the to keep the application. over the affected area dry and free area dry. area twice per day. | from infection. 4. Bleeding. Neat hydrosol | Prepacked Apply the wound The hydrosol helped wound hydrosol wound | dressing with blood staunching ‘dressing. dressing. immediately to and provided an injured area and immediate anti- secure with inflammatory bandage or plaster. | treatment. It also
Leave on until help | provided an arrives. antibacterial action and a barrier to further infection of the wound.
Hydrosol Spray. Spray a thin film Stopped bleeding and : spray. - | over the affected helped to heal the area immediately wound. after injury. .
Neat hydrosol. | Towelette Use to clean Non irritating. wipes. surrounding skin ‘| and remove debris etc.
Neat hydrosol | Foil pre-packed | Apply compress Provided an or hydrosol hydrosol immediately to immediate anti- gel. compress. injured area and | inflammatory secure with - | treatment and bandage or plaster | provided an for a period of time, | antibacterial action : usually once a day. | and a barrier to : further infection of the } wound. 5. Burn wounds Neat Hydrosol | Prepacked Apply to area and (minor and with gelling hydrosol face leave for a few aggravated burn agent. mask or body minutes. Repeat wounds). towelette several times per : day as needed
.2010/ 04258
Neat hydrosol | Spray Spray a thin film Resulted in cooling (to keep application. twice per day. and easing of wound dry). .| redness and sensitivity of the skin.
Kept area dry and acted as an anti- inflammatory. 6. Sprains, muscle Hydrosol with | Prepacked Apply on injured Eased pain and aches and sports ~~ | gelling agent. hydrosol gel area onceaday | reduced injuries. wound dressing. | until symptoms inflammation.
Co disappear. 7. Sensitive skin and | Hydrosol. Spray Spray a thin film Resulted in cooling redness as a result of application twice per day on the | and eased redness radiotherapy (especially for affected area until and sensitivity of the treatment. : sensitive areas - | symptoms skin. Keptareadry no rubbing). disappear. and acted as an anti- inflammatory.
Hydrosol gel. Tube. Apply a thin film over the infected area twice per day until symptoms . disappear.
Prepacked Towelettes to Remove foil Resulted in cooling hydrosol with clean and sooth | packaging, unfold and eased redness gelling agent the sensitive towelette and use to | and sensitivity of the “towelettes. area. clean the area if skin. Kept area clean needed. and acted as an anti- inflammatory. The hydrosol did not burn the eyes or irritate the } : skin. 8. Enhance Neat Hydrosol. | Spray Apply a thin film effectiveness of application. over the face and chemotherapeutic body twice per day and other medication after a bath. This in the case of drug can be done also resistance. before and after : chemotherapeutic treatments.
Hydrosol in a Tube. Apply lotion all over water soluble the body and carrier cream. massage lightly for approximately 5 minutes twice a day.
Claims (9)
1. The use of a hydrosol produced by the steam distillation of a plant of the genus Pelargonium in the manufacture of a skin product for the treatment of haemorrhoids, mouth sores, wounds, burns, muscle injuries, skin conditions caused by radiotherapy, skin conditions : caused by beauty surgery, sensitive skin caused by beauty treatment, skin lesions, skin growths, fungal skin infections, bacterial skin infections, inflammation caused by lymphedema; oo the prevention of infection; enhancing the effectiveness of chemotherapeutic treatment; or enhancing absorption and penetration of therapeutic substances through the skin.
15. 2. The use as claimed in Claim 1, in which the plant of the genus Pelargonium is a plant of the species Pelargonium alveolens.
3. The use as claimed in Claim 1 or Claim 2, in which the hydrosol is produced by steam distillation of the leaves of the plant.
4, The use as claimed in Claim 3, in which the hydrosol is a lower oil-saturated aqueous layer of a two phase distillate comprising an upper essential oil layer and the lower layer.
5. The use as claimed in any one of Claims 2 to 4 inclusive, in which the plant of the species Pelargonium alveolens is the variety Bourbon.
6. A substance or composition for use in the treatment of haemorrhoids, mouth sores, wounds, burns, muscle injuries, skin conditions caused by radiotherapy, skin conditions
: 2010/ 04258 ® caused by beauty surgery, sensitive skin caused by beauty treatment, skin lesions, skin growths, fungal skin infections, bacterial skin infections, inflammation caused by lymphedema; the prevention of infection; oo enhancing the effectiveness of chemotherapeutic treatment; or enhancing absorption and penetration of therapeutic substances through the skin, the substance or composition comprising a hydrosol produced by the : steam distillation of a plant of the genus Pelargonium. oo
7. A substance or composition as claimed in Claim 6, in which the plant of the genus Pelargonium is a plant of the species Pelargonium alveolens.
8. A substance or composition as claimed in Claim 6 or Claim 7, in which the hydrosol is produced by steam distillation of the leaves of the plant.
’
9. A substance or composition as claimed in Claim 8, in which : the hydrosol is a lower oil-saturated aqueous layer of a two phase distillate comprising an upper essential oil layer and the lower layer.
10. A substance or composition as claimed in any one of Claims 2 to 4 inclusive, in which the plant of the species Pelargonium alveolens is : the variety Bourbon. : :
11. A product for use on the skin, the product being in a form selected from sprays, towelettes, wipes, face masks, gels, creams, massage lotions, lubricating carrier creams, skin patches and bandages and comprising a hydrosol produced by the steam distillation of a plant of the genus Pelargonium.
. : ” * : : d
12. The product as claimed in Claim 10, in which the plant of the genus Pelargonium is a plant of the species Pelargonium alveolens.
13. The product as claimed in Claim 10 or Claim 11, in which the hydrosol is produced by steam distillation of the leaves of the plant.
14. The product as claimed in Claim 12, in which the hydrosol is . a lower oil-saturated aqueous layer of a two phase distillate comprising an upper essential oil layer and the lower layer.
15. The product as claimed in any one of Claims 11 to 13 inclusive, in which the plant of the species Pelargonium alveolens is the : variety Bourbon.
16. A use as claimed in Claim 1, substantially as herein described with reference to any of the Examples.
17. A substance or composition as claimed in Claim 6, substantially as herein described with reference to any of the Examples.
18. . A product as claimed in Claim 10, substantially as herein described with reference to any of the Examples. oo 25 DATED THIS 1%} DAY OF JUNE 2010 - /~—ADAMS & ADAMS APPLICANTS PATENT ATTORNEYS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA200906885 | 2009-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201004258B true ZA201004258B (en) | 2011-03-30 |
Family
ID=61026672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/04258A ZA201004258B (en) | 2009-10-02 | 2010-06-15 | Hydrosol composition |
Country Status (1)
| Country | Link |
|---|---|
| ZA (1) | ZA201004258B (en) |
-
2010
- 2010-06-15 ZA ZA2010/04258A patent/ZA201004258B/en unknown
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