ZA200807488B - Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes - Google Patents

Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes

Info

Publication number
ZA200807488B
ZA200807488B ZA200807488A ZA200807488A ZA200807488B ZA 200807488 B ZA200807488 B ZA 200807488B ZA 200807488 A ZA200807488 A ZA 200807488A ZA 200807488 A ZA200807488 A ZA 200807488A ZA 200807488 B ZA200807488 B ZA 200807488B
Authority
ZA
South Africa
Prior art keywords
aminotetrahydropyrans
diabetes
inhibitors
prevention
treatment
Prior art date
Application number
ZA200807488A
Inventor
Biftu Tesfaye
Ann E Weber
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA200807488B publication Critical patent/ZA200807488B/en

Links

ZA200807488A 2006-03-28 2008-09-01 Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes ZA200807488B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78651806P 2006-03-28 2006-03-28

Publications (1)

Publication Number Publication Date
ZA200807488B true ZA200807488B (en) 2009-11-25

Family

ID=40572753

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807488A ZA200807488B (en) 2006-03-28 2008-09-01 Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes

Country Status (2)

Country Link
CN (1) CN101410400B (en)
ZA (1) ZA200807488B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102595897A (en) * 2009-09-02 2012-07-18 默沙东公司 Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
TWI500613B (en) * 2012-10-17 2015-09-21 Cadila Healthcare Ltd Novel heterocyclic compounds
CN105085528A (en) * 2014-05-15 2015-11-25 成都贝斯凯瑞生物科技有限公司 Aminotetrahydropyran derivative as dipeptidyl peptidase-IV inhibitor
CN105085530B (en) * 2014-05-23 2019-01-04 四川海思科制药有限公司 Ternary condenses cyclosubstituted amino hexatomic ring analog derivative and its application in medicine
ES2963299T3 (en) * 2014-06-17 2024-03-26 Sichuan Haisco Pharmaceutical Co Ltd Aminopyranoid ring derivative and composition and use thereof
CN105294694B (en) * 2014-06-18 2019-01-04 四川海思科制药有限公司 Amino hexatomic ring analog derivative and its application in medicine
CN105985357A (en) * 2015-02-12 2016-10-05 北京赛林泰医药技术有限公司 Substituted six-component saturated heteroalicyclic long-acting DPP-IV inhibitor
CN106478631B (en) * 2015-08-24 2019-04-05 四川科伦药物研究院有限公司 The preparation method of long-acting dipeptidyl peptidase-iv inhibitor, purposes and its intermediate
WO2017031918A1 (en) * 2015-08-24 2017-03-02 四川科伦药物研究院有限公司 Long-acting dipeptidyl peptidase-iv inhibitor, applications, and preparation method for intermediate thereof
CN106916158A (en) * 2015-12-25 2017-07-04 四川海思科制药有限公司 A kind of preparation method of pyran derivate hydrochloride hydrate and its intermediate
CN107849051B (en) * 2015-12-25 2020-11-13 四川海思科制药有限公司 Crystalline forms of substituted aminopyrane derivatives
WO2017202365A1 (en) * 2016-05-25 2017-11-30 四川海思科制药有限公司 Preparation method for trifluoromethyl-substituted pyran derivative
CN109071551B (en) * 2016-05-25 2020-12-08 四川海思科制药有限公司 Preparation method of trifluoromethyl substituted pyran derivative
CN109796455B (en) * 2017-11-17 2021-02-26 四川海思科制药有限公司 Salt of aminopyrane derivative, crystal form of salt, preparation method and application of salt
EP3750539A4 (en) * 2018-02-06 2021-12-15 Sichuan Haisco Pharmaceutical Co., Ltd. Composition of aminopyran derivative
CN111269218A (en) * 2018-12-04 2020-06-12 四川海思科制药有限公司 Trifluoromethyl substituted aminopyrane ring derivatives, and compositions and uses thereof

Also Published As

Publication number Publication date
CN101410400A (en) 2009-04-15
CN101410400B (en) 2012-09-05

Similar Documents

Publication Publication Date Title
EP1986652A4 (en) Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1978804A4 (en) Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP2019677A4 (en) Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
IL212485A0 (en) Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
ZA200807488B (en) Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
EP1761532A4 (en) Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP2190428A4 (en) Heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP2094081A4 (en) Tricyclic heteroaromatic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP2473047A4 (en) Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1756106A4 (en) Cyclohexylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1962601A4 (en) Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
ZA200802857B (en) Dipeptidyl peptidase inhibitors for treating diabetes
IL190133A0 (en) Dipeptidyl peptidase inhibitors for treating diabetes
EP1756074A4 (en) 1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP2480082A4 (en) Substituted aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
PL2247602T3 (en) Adamantyl o-glucuronide derivatives as inhibitors of dipeptidyl peptidase iv for the treatment of diabetes
ZA200704154B (en) Substituted benzoquinolizines as DPP-IV inhibitors for the treatment of diabetes
AP2007004234A0 (en) Dipeptidyl peptidase-IV inhibitors
EP1592689A4 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1589969A4 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
ZA200808282B (en) Uses of DPP-IV inhibitors
HK1148435A1 (en) Oxadiazoanthracene compounds for the treatment of diabetes
IL193484A0 (en) Gsk-3 inhibitors for the treatment of osteoporosis
EP2538783A4 (en) Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
ZA200802855B (en) Dipeptidyl peptidase inhibitors for treating diabetes