ZA200801332B - Pentacyclic kinase inhibitors - Google Patents
Pentacyclic kinase inhibitorsInfo
- Publication number
- ZA200801332B ZA200801332B ZA200801332A ZA200801332A ZA200801332B ZA 200801332 B ZA200801332 B ZA 200801332B ZA 200801332 A ZA200801332 A ZA 200801332A ZA 200801332 A ZA200801332 A ZA 200801332A ZA 200801332 B ZA200801332 B ZA 200801332B
- Authority
- ZA
- South Africa
- Prior art keywords
- kinase inhibitors
- pentacyclic
- malignancies
- compounds
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70790205P | 2005-08-12 | 2005-08-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200801332B true ZA200801332B (en) | 2009-10-28 |
Family
ID=37607426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200801332A ZA200801332B (en) | 2005-08-12 | 2008-02-07 | Pentacyclic kinase inhibitors |
Country Status (14)
Country | Link |
---|---|
US (1) | US7749994B2 (xx) |
EP (1) | EP1919920B1 (xx) |
JP (1) | JP2009504680A (xx) |
KR (1) | KR20080035691A (xx) |
CN (1) | CN101287737A (xx) |
AT (1) | ATE509933T1 (xx) |
AU (1) | AU2006279659A1 (xx) |
BR (1) | BRPI0615141A2 (xx) |
CA (1) | CA2619276A1 (xx) |
IL (1) | IL189296A0 (xx) |
NO (1) | NO20081292L (xx) |
RU (1) | RU2008108903A (xx) |
WO (1) | WO2007022102A2 (xx) |
ZA (1) | ZA200801332B (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5501251B2 (ja) | 2008-01-11 | 2014-05-21 | アルバニー モレキュラー リサーチ, インコーポレイテッド | Mch拮抗薬としての(1−アジノン)置換ピリドインドール類 |
US9073925B2 (en) * | 2009-07-01 | 2015-07-07 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003007A1 (en) * | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
WO2011003012A1 (en) * | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
EP2448585B1 (en) * | 2009-07-01 | 2014-01-01 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof |
US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
JP6653573B2 (ja) | 2012-05-22 | 2020-02-26 | トラスティーズ・オブ・ダートマウス・カレッジ | シクロアルカニル[b]インドール、シクロアルカニル[b]ベンゾフラン、シクロアルカニル[b]ベンゾチオフェンを合成するための方法、化合物および使用の方法 |
WO2017162661A1 (en) | 2016-03-22 | 2017-09-28 | Bayer Pharma Aktiengesellschaft | 1h-benzo[de]isoquinoline-1,3(2h)-diones |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050032869A1 (en) | 2003-07-08 | 2005-02-10 | Pharmacia Italia S.P.A. | Pyrazolyl-indole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
WO2006133885A1 (en) | 2005-06-15 | 2006-12-21 | F. Hoffmann-La Roche Ag | Tricyclic fused indole derivatives and their use as aurora kinase inhibitors |
-
2006
- 2006-08-14 BR BRPI0615141-8A patent/BRPI0615141A2/pt not_active IP Right Cessation
- 2006-08-14 US US11/503,405 patent/US7749994B2/en not_active Expired - Fee Related
- 2006-08-14 RU RU2008108903/04A patent/RU2008108903A/ru not_active Application Discontinuation
- 2006-08-14 CN CNA200680037951XA patent/CN101287737A/zh active Pending
- 2006-08-14 JP JP2008526286A patent/JP2009504680A/ja active Pending
- 2006-08-14 AU AU2006279659A patent/AU2006279659A1/en not_active Abandoned
- 2006-08-14 EP EP06813425A patent/EP1919920B1/en active Active
- 2006-08-14 AT AT06813425T patent/ATE509933T1/de not_active IP Right Cessation
- 2006-08-14 WO PCT/US2006/031682 patent/WO2007022102A2/en active Application Filing
- 2006-08-14 KR KR1020087005941A patent/KR20080035691A/ko not_active Application Discontinuation
- 2006-08-14 CA CA002619276A patent/CA2619276A1/en not_active Abandoned
-
2008
- 2008-02-05 IL IL189296A patent/IL189296A0/en unknown
- 2008-02-07 ZA ZA200801332A patent/ZA200801332B/xx unknown
- 2008-03-11 NO NO20081292A patent/NO20081292L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1919920B1 (en) | 2011-05-18 |
WO2007022102A3 (en) | 2007-05-10 |
ATE509933T1 (de) | 2011-06-15 |
BRPI0615141A2 (pt) | 2009-07-14 |
CN101287737A (zh) | 2008-10-15 |
US7749994B2 (en) | 2010-07-06 |
IL189296A0 (en) | 2008-06-05 |
AU2006279659A1 (en) | 2007-02-22 |
JP2009504680A (ja) | 2009-02-05 |
WO2007022102A2 (en) | 2007-02-22 |
US20070037791A1 (en) | 2007-02-15 |
NO20081292L (no) | 2008-05-13 |
CA2619276A1 (en) | 2007-02-22 |
KR20080035691A (ko) | 2008-04-23 |
EP1919920A2 (en) | 2008-05-14 |
RU2008108903A (ru) | 2009-09-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2007120333A3 (en) | Tetracyclic kinase inhibitors | |
ZA200801332B (en) | Pentacyclic kinase inhibitors | |
TW200740815A (en) | P38 MAP kinase inhibitors and methods for using the same | |
TW200800999A (en) | Novel compounds | |
ZA200704910B (en) | Pyrrolidine inhibitors of IAP | |
MX2007005932A (es) | 1-alquinil-2-ariloxialquilamidas y su uso como fungicidas. | |
GEP20105024B (en) | Fused heterocyclic compound | |
MX2009014247A (es) | Compuestos heterociclicos utiles como inhibidores de mk2. | |
JO3134B1 (ar) | مثبطات نشاط akt | |
TW200612910A (en) | Medicaments comprising carbonyl compounds, and the use thereof | |
UA96565C2 (ru) | Пиридильные ингибиторы хеджхоговской передачи сигнала | |
TW200801003A (en) | Novel compounds | |
MX2009003157A (es) | Pirazoliltienopiridinas terapeuticas. | |
MX2009009290A (es) | Compuestos activos en ppar. | |
UA85505C2 (xx) | Інгібітори кінази$ингибиторы киназы | |
TW200740776A (en) | N-phenylbenzotriazolyl c-kit inhibitors | |
TNSN08191A1 (en) | Kinase inhibitors | |
MX2008001538A (es) | Aril piridinas y metodos para su uso. | |
TW200700064A (en) | Novel compounds | |
WO2007097981A3 (en) | Alpha carbolines and uses thereof | |
TW200634013A (en) | Quinoline derivative, its use, production and pharmaceutical agents containing the derivative | |
MX2010007543A (es) | Inhibidores de iap. | |
TW200510398A (en) | Novel compounds | |
TW200744612A (en) | New combination | |
MY155342A (en) | Antitumoral compounds |