US5733524A
(en)
|
1984-03-19 |
1998-03-31 |
The Picower Institute For Medical Research |
Methods and materials for the diagnosis and treatment of conditions such as stroke
|
US5869534A
(en)
|
1992-05-21 |
1999-02-09 |
The Picower Institute For Medical Research |
Glycosylation of lipids and lipid-containing particles, and diagnostic and therapeutic methods and materials derived therefrom
|
US5733933A
(en)
|
1984-03-19 |
1998-03-31 |
The Picower Institute For Medical Research |
Methods and materials for the diagnosis and treatment of conditions such as stroke
|
US5700447A
(en)
|
1992-05-21 |
1997-12-23 |
The Picowder Institute For Medical Research |
Methods and materials for the diagnosis and treatment of conditions such as stroke
|
US5801200A
(en)
|
1984-03-19 |
1998-09-01 |
The Picower Institute For Medical Research |
Methods and materials for the diagnosis and treatment of conditions such as stroke
|
ATE70301T1
(en)
|
1986-02-17 |
1991-12-15 |
Stichting Centraal Lab |
TISSUE PLASMINOGEN ACTIVATOR MUTANT, ENCODING RECOMBINANT GENETIC INFORMATION THEREOF AND METHODS FOR THE PRODUCTION OF SUCH MUTANTS, THEIR USE AND PHARMACEUTICAL COMPOSITIONS.
|
EP0319144A1
(en)
|
1987-11-06 |
1989-06-07 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Adsorbent of beta 2-microglobulin
|
DE3853219T2
(en)
|
1987-11-20 |
1995-06-29 |
Kanegafuchi Chemical Ind |
Method of removing serum amyloid protein.
|
US5216127A
(en)
|
1987-11-20 |
1993-06-01 |
Kanegafuchi Kagaku Kogyo Kabushiki Kaisha |
Adsorbent for serum amyloid protein
|
US5151082A
(en)
|
1988-08-05 |
1992-09-29 |
Heathdyne, Inc. |
Apparatus and method for kidney dialysis using plasma in lieu of blood
|
CA1335361C
(en)
|
1989-05-24 |
1995-04-25 |
Andrei Z. Budzynski |
Thrombus-targeted complexes of plasminogen activator and fibrin fragments
|
US5180615A
(en)
|
1989-12-13 |
1993-01-19 |
W.R. Grace & Co.-Conn. |
Metallized bag for static protection of electronic components
|
US5591431A
(en)
|
1990-03-09 |
1997-01-07 |
G.D. Searle & Co. |
Enhancement of clot lysis
|
US5753624A
(en)
|
1990-04-27 |
1998-05-19 |
Milkhaus Laboratory, Inc. |
Materials and methods for treatment of plaquing disease
|
US5650418A
(en)
|
1990-06-04 |
1997-07-22 |
Therapy 2000 |
Therapeutic lysine salt composition and method of use
|
US5278189A
(en)
|
1990-06-04 |
1994-01-11 |
Rath Matthias W |
Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A)
|
US5230996A
(en)
|
1990-06-04 |
1993-07-27 |
Therapy 2000 |
Use of ascorbate and tranexamic acid solution for organ and blood vessel treatment prior to transplantation
|
US5780587A
(en)
|
1990-08-24 |
1998-07-14 |
President And Fellows Of Harvard College |
Compounds and methods for inhibiting β-protein filament formation and neurotoxicity
|
SE468881B
(en)
|
1991-01-09 |
1993-04-05 |
Kabi Pharmacia Ab |
APPLICATION OF CERTAIN PHARMACEUTICALS FOR THE PREPARATION OF MEDICINAL PRODUCTS FOR TREATMENT OF ENDOTOXIN-INDEXED EFFECTS AND THE PREPARATION OF ENDOTOXINES FROM MISCELLANEOUS SOLUTIONS
|
US5221628A
(en)
|
1991-03-19 |
1993-06-22 |
Northwestern University |
Binding of aggregated immunoglobulin or immune complexes by serum amyloid P component
|
US5276059A
(en)
|
1992-07-10 |
1994-01-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibition of diseases associated with amyloid formation
|
CA2101614A1
(en)
|
1992-07-30 |
1994-01-31 |
Shmuel Shaltiel |
Synthetic peptides derived from vitronectin and pharmaceutical compositions comprising them
|
US5958883A
(en)
|
1992-09-23 |
1999-09-28 |
Board Of Regents Of The University Of Washington Office Of Technology |
Animal models of human amyloidoses
|
DE4242736A1
(en)
|
1992-12-17 |
1994-06-23 |
Behringwerke Ag |
Synthetic peptides, antibodies against them and their use
|
US5955343A
(en)
|
1992-12-28 |
1999-09-21 |
Massachusetts Institute Of Technology |
Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
|
US5750349A
(en)
|
1993-01-25 |
1998-05-12 |
Takeda Chemical Industries Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
US5691135A
(en)
*
|
1993-01-26 |
1997-11-25 |
The Regents Of The University Of California |
Immunoglobulin superantigen binding to gp 120 from HIV
|
US5786327A
(en)
*
|
1993-03-12 |
1998-07-28 |
Gensci Regeneration Sciences Inc. |
Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
|
US5449663A
(en)
|
1993-06-11 |
1995-09-12 |
Bicher; Haim I. |
Antineoplastic compositions
|
JP3537440B2
(en)
|
1993-12-17 |
2004-06-14 |
持田製薬株式会社 |
Method for stabilizing soluble thrombomodulin for long-term storage
|
US6410598B1
(en)
|
1994-02-03 |
2002-06-25 |
Michael P. Vitek |
Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
|
JPH09511492A
(en)
|
1994-02-03 |
1997-11-18 |
ザ ピコワー インスティテュート フォア メディカル リサーチ |
Compositions and methods for advanced glycosylation end product mediated modulation of amyloidosis
|
KR0163563B1
(en)
|
1994-03-23 |
1998-12-01 |
김종인 |
Topical drug in combination for treatment of skin lesions
|
US5786324A
(en)
|
1994-03-24 |
1998-07-28 |
Regents Of The University Of Minnesota |
Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
|
US6136548A
(en)
|
1994-11-22 |
2000-10-24 |
Rutgers, The State University Of New Jersey |
Methods for identifying useful T-PA mutant derivatives for treatment of vascular hemorrhaging
|
US5589154A
(en)
|
1994-11-22 |
1996-12-31 |
Rutgers, The State University Of New Jersey |
Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
|
US5888774A
(en)
|
1994-12-19 |
1999-03-30 |
Cangene Corporation |
Recombinant DNA molecules and expression vectors for erythropoietin
|
US6319498B1
(en)
*
|
1995-03-14 |
2001-11-20 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
US5817626A
(en)
|
1995-03-14 |
1998-10-06 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation
|
US5854215A
(en)
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
US5948763A
(en)
|
1995-06-07 |
1999-09-07 |
New York University |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits
|
US6436969B1
(en)
|
1995-09-12 |
2002-08-20 |
Kansas University Medical Center Research Institute Inc. |
Dialysis solutions and methods
|
AU7253596A
(en)
|
1995-10-02 |
1997-04-28 |
Mohammad W. Katoot |
Biologically-active polymers
|
US5985242A
(en)
|
1995-10-27 |
1999-11-16 |
Praecis Pharmaceuticals, Inc. |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
US6310046B1
(en)
|
1995-11-17 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Sequestrin of Plasmodium falciparum
|
AU1529297A
(en)
|
1996-01-24 |
1997-08-20 |
Warner-Lambert Company |
Method of imaging amyloid deposits
|
US5785187A
(en)
*
|
1996-04-29 |
1998-07-28 |
Lipman; Daniel |
Mechandising display assembly
|
US6034211A
(en)
|
1996-06-03 |
2000-03-07 |
Kelly; Jeffery W. |
β-sheet nucleating peptidomimetics
|
US6929807B1
(en)
|
1996-08-09 |
2005-08-16 |
Mannatech, Inc. |
Compositions of plant carbohydrates as dietary supplements
|
US6689275B1
(en)
*
|
1996-12-31 |
2004-02-10 |
Ajay Gupta |
Method and pharmaceutical composition for replacing iron losses in dialysis patients
|
US6372473B1
(en)
|
1997-05-28 |
2002-04-16 |
Human Genome Sciences, Inc. |
Tissue plasminogen activator-like protease
|
US20020122807A1
(en)
|
1998-07-07 |
2002-09-05 |
Dan Michael D. |
Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
|
DE19735902A1
(en)
|
1997-08-19 |
1999-02-25 |
Imtec Immundiagnostika Gmbh |
New selective adsorbent carrying peptide(s) that mimic complement C1q
|
ATE241365T1
(en)
|
1997-08-28 |
2003-06-15 |
Univ Washington |
PREPARATIONS CONTAINING SACCHARIDE FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES
|
JP2001521002A
(en)
|
1997-10-24 |
2001-11-06 |
コーネル リサーチ ファンデーション インク. |
Nutritional supplements for brain metabolic dysfunction
|
JP4037525B2
(en)
|
1998-03-25 |
2008-01-23 |
生化学工業株式会社 |
New antibacterial peptide
|
US7041287B2
(en)
|
1998-05-21 |
2006-05-09 |
Trustees Of The University Of Pennsylvania |
Compositions and methods for selective dissolution of nascent intravascular blood clots
|
WO2000009562A1
(en)
|
1998-08-12 |
2000-02-24 |
The New York Blood Center, Inc. |
Novel cleaved fragments of fibrinogen
|
WO2000018398A1
(en)
|
1998-09-25 |
2000-04-06 |
Sunol Molecular Corporation |
Pharmaceutically active compounds and methods of use thereof
|
IN190822B
(en)
|
1998-12-24 |
2003-08-23 |
Council Scient Ind Res |
|
US6242473B1
(en)
|
1999-01-08 |
2001-06-05 |
Maxim Pharmaceuticals, Inc. |
Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
|
US6161547A
(en)
|
1999-01-15 |
2000-12-19 |
Coaxia, Inc. |
Medical device for flow augmentation in patients with occlusive cerebrovascular disease and methods of use
|
DE60026501T2
(en)
|
1999-04-30 |
2006-08-10 |
Matsumoto, Akira |
HUMAN BRAIN SPECIFIC CARBOXYPEPTIDASE B
|
AT500670A1
(en)
|
1999-05-19 |
2006-02-15 |
Bio & Bio Licensing Sa |
DRUGS FOR LOCAL APPLICATION
|
DK1409654T3
(en)
|
1999-06-16 |
2008-12-08 |
Boston Biomedical Res Inst |
Immunological control of beta-amyloid levels in vivo
|
GB9917725D0
(en)
|
1999-07-28 |
1999-09-29 |
Medical Res Council |
Peptides
|
WO2001012598A2
(en)
|
1999-08-13 |
2001-02-22 |
The Trustees Of Columbia University In The City Of New York |
METHODS OF INHIBITING BINDING OF β-SHEET FIBRIL TO RAGE AND CONSEQUENCES THEREOF
|
US20040013647A1
(en)
|
1999-09-03 |
2004-01-22 |
Ramot At Tel-Aviv University Ltd. |
Methods and compositions for treating a plaque-forming disease
|
KR100681632B1
(en)
|
1999-09-14 |
2007-02-09 |
메이지 세이카 가이샤 리미티드 |
Phosphonic acid derivatives having carboxypeptidase B inhibitory activity
|
US6399314B1
(en)
|
1999-12-29 |
2002-06-04 |
American Cyanamid Company |
Methods of detection of amyloidogenic proteins
|
EP1252181B1
(en)
|
2000-01-20 |
2006-01-18 |
Regents Of The University Of Minnesota |
Peptides with antibacterial activity
|
AU3173301A
(en)
|
2000-02-11 |
2001-08-20 |
European Molecular Biology Laboratory |
Methods and compositions for treatment of alzheimer's disease by enhancing plasmin or plasmin-like activity
|
JP5025871B2
(en)
|
2000-02-21 |
2012-09-12 |
エイチ.リュンドベック エイ/エス |
A novel method for down-regulation of amyloid
|
KR100879810B1
(en)
|
2000-02-21 |
2009-01-22 |
하. 룬드벡 아크티에셀스카브 |
Novel method for down-regulation of amyloid
|
EP1130031A1
(en)
|
2000-02-25 |
2001-09-05 |
Universitair Medisch Centrum Utrecht |
Method for inhibiting angiogenesis using molecules that enhance plasmin formation or prolong plasmin activity
|
WO2001070762A2
(en)
|
2000-03-21 |
2001-09-27 |
Research Foundation Of State University Of New York |
Adsorption of polyampholytes to charged surfaces and assays incorporating same
|
RU2324686C2
(en)
|
2000-08-24 |
2008-05-20 |
Юнивесити Оф Питсбэг |
AMYLOID-BINDING THIOFLAVIN DERIVATIVES, METHOD OF in vivo DETECTION OF AMYLOID DEPOSIT AND METHOD OF DIAGNOSTICS OF ALZHEIMER'S DISEASE
|
US7270800B2
(en)
|
2000-08-24 |
2007-09-18 |
University Of Pittsburgh |
Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
|
EP1186299A1
(en)
|
2000-09-12 |
2002-03-13 |
Universitair Medisch Centrum Utrecht |
The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system
|
DE60032250T2
(en)
|
2000-12-28 |
2007-03-15 |
Biomay Produktions- Und Handels-Aktiengesellschaft |
Treatment of allergies
|
WO2002099098A1
(en)
|
2001-04-04 |
2002-12-12 |
American Diagnostica, Inc |
Method of preparation of stabilized thrombin-activatable fibrinolysis inhibitor (tafi) and methods of use thereof
|
AU2002320045B2
(en)
|
2001-05-31 |
2008-05-08 |
Adlyfe, Inc. |
Misfolded protein sensor method
|
US6960465B1
(en)
*
|
2001-06-27 |
2005-11-01 |
Northwestern University |
Increased cell resistance to toxic organic substances
|
US6737401B2
(en)
|
2001-06-28 |
2004-05-18 |
Metronic Minimed, Inc. |
Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
|
AU2002312566A1
(en)
|
2001-07-09 |
2003-01-29 |
Elan Pharmaceuticals, Inc. |
Methods of inhibiting amyloid toxicity
|
JP2003024080A
(en)
*
|
2001-07-19 |
2003-01-28 |
Univ Tokyo |
Protein inducing p53-dependent apoptosis and method for screening apoptosis controlling agent
|
GB0202275D0
(en)
|
2002-01-31 |
2002-03-20 |
Hansa Medica Ab |
Peptide
|
EP1820806A1
(en)
|
2006-02-16 |
2007-08-22 |
Crossbeta Biosciences B.V. |
Affinity regions
|
EP1478931B2
(en)
|
2002-02-28 |
2018-11-07 |
Microsens Biophage Limited |
Binding of pathological forms of prion proteins
|
KR100518152B1
(en)
*
|
2002-05-09 |
2005-09-29 |
메디제네스(주) |
A Pharmaceutical Composition for Treatment of Wounds Containing Blood Plasma or Serum
|
US20070003552A1
(en)
|
2002-07-09 |
2007-01-04 |
Gebbink Martijn F B |
Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation
|
EP1380290A1
(en)
|
2002-07-09 |
2004-01-14 |
Universitair Medisch Centrum Utrecht |
Cross-beta structure pathway and its therapeutic relevance
|
US20050142611A1
(en)
*
|
2002-09-30 |
2005-06-30 |
Auburn University |
Method of isolation and self-assembly of small protein particles from blood and other biological materials
|
US7470667B2
(en)
*
|
2002-12-05 |
2008-12-30 |
Medgenn (Hong Kong) Ltd |
Methods of treating cancer using a modified endostatin protein
|
EP1449536A1
(en)
*
|
2003-02-14 |
2004-08-25 |
Prionics AG |
Prion proteins (PrP) as therapeutic agents for the treatment of AP-1 associated diseases
|
US7172875B2
(en)
|
2003-02-18 |
2007-02-06 |
The Ohio State University Research Foundation |
Identifying inhibitors of intracellular protein fibrillization
|
EP3192872A1
(en)
|
2003-08-26 |
2017-07-19 |
The Regents of the University of Colorado, a body corporate |
Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
|
US7427659B2
(en)
|
2003-10-24 |
2008-09-23 |
Amgen Inc. |
Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
|
WO2006006172A2
(en)
|
2004-07-15 |
2006-01-19 |
Ramot At Tel Aviv University Ltd. |
Use of anti-amyloid agents for treating and typing pathogen infections
|
JP2008531553A
(en)
|
2005-02-25 |
2008-08-14 |
メディジーンズ カンパニー リミテッド |
Pharmaceutical composition for the treatment of Avellino corneal dystrophy comprising plasma or serum
|
EP1704867A1
(en)
|
2005-03-18 |
2006-09-27 |
Crossbeta Biosciences B.V. |
Cross-beta structures on microbial organisms
|
US20090202980A1
(en)
|
2005-03-21 |
2009-08-13 |
Crossbeta Biosciences B.V. |
Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation
|
EP1910844B1
(en)
|
2005-07-13 |
2012-04-18 |
Crossbeta Biosciences B.V. |
Cross-beta structure binding compounds
|
BRPI0613525A2
(en)
|
2005-07-13 |
2011-05-31 |
Crossbeta Biosciences Bv |
methods for producing an immunogenic composition, for enhancing the immunogenicity of a composition, for enhancing the immunogenicity of a vaccine composition, and for determining the amount of beta-cross structures in a vaccine composition, uses of beta-cross structures, and an immunogenic composition, subunit vaccine, and immunogenic composition
|
US20070015133A1
(en)
|
2005-07-13 |
2007-01-18 |
Umc Utrecht Holding B.V. |
Method for detecting and/or removing protein and/or peptide comprising a cross-beta structure from an aqueous solution comprising a protein
|
US8114832B2
(en)
|
2005-07-13 |
2012-02-14 |
Crossbeta Biosciences B.V. |
Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
|
US20080249606A1
(en)
|
2005-07-13 |
2008-10-09 |
Martijn Frans Ben Gerard Gebbink |
Methods for Determining the Effect of a Treatment on the Cross-Beta Structure Content of a Protein; Selection of Treatments and Uses Thereof
|
JP2009504636A
(en)
|
2005-08-11 |
2009-02-05 |
メディジーンズ カンパニー リミテッド |
Pharmaceutical composition for treatment of nerve injury comprising plasma or serum
|
US8543424B2
(en)
|
2005-12-30 |
2013-09-24 |
Darryl Mark Hunsaker |
Vehicle insurance status display system
|
CA2645930A1
(en)
|
2006-03-17 |
2007-09-27 |
Crossbeta Biosciences B.V. |
Methods of binding of cross-beta structures by chaperones
|
US8071670B2
(en)
*
|
2006-05-11 |
2011-12-06 |
Akzo Nobel Chemicals International B.V. |
Aqueous dispersions of polyvinylacetate and silica, processes for preparing the same, uses therefor and substrates coated and/or bonded therewith
|
HUE030269T2
(en)
*
|
2006-06-26 |
2017-04-28 |
Macrogenics Inc |
Fc riib-specific antibodies and methods of use thereof
|
EP2058001A1
(en)
|
2007-11-08 |
2009-05-13 |
Crossbeta Biosciences B.V. |
Enhancement of immunogenicity of antigens
|
EP2058000A1
(en)
*
|
2007-11-08 |
2009-05-13 |
Crossbeta Biosciences B.V. |
Immunogenic compositions capable of activating T cells
|