ZA200708811B - Use of a sulfonamide compound for improving the pharma-cokinetics of a drug - Google Patents

Use of a sulfonamide compound for improving the pharma-cokinetics of a drug

Info

Publication number
ZA200708811B
ZA200708811B ZA200708811A ZA200708811A ZA200708811B ZA 200708811 B ZA200708811 B ZA 200708811B ZA 200708811 A ZA200708811 A ZA 200708811A ZA 200708811 A ZA200708811 A ZA 200708811A ZA 200708811 B ZA200708811 B ZA 200708811B
Authority
ZA
South Africa
Prior art keywords
cokinetics
pharma
drug
improving
sulfonamide compound
Prior art date
Application number
ZA200708811A
Inventor
T Klooster Gerben Albert Eleutherius Van
De Meyer Sandra
De Kock Herman Augustinus
Piet Tom Bert Paul Wigerinck
Lieven Elvire Colette Baert
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of ZA200708811B publication Critical patent/ZA200708811B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200708811A 2005-04-15 2007-10-12 Use of a sulfonamide compound for improving the pharma-cokinetics of a drug ZA200708811B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05103035 2005-04-15

Publications (1)

Publication Number Publication Date
ZA200708811B true ZA200708811B (en) 2009-01-28

Family

ID=35589560

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200708811A ZA200708811B (en) 2005-04-15 2007-10-12 Use of a sulfonamide compound for improving the pharma-cokinetics of a drug

Country Status (12)

Country Link
US (1) US8557854B2 (en)
EP (1) EP1874307A2 (en)
JP (1) JP2008535896A (en)
CN (1) CN101175491B (en)
AR (1) AR053845A1 (en)
AU (1) AU2006234335B2 (en)
BR (1) BRPI0608322A2 (en)
CA (1) CA2604799C (en)
EA (1) EA016340B1 (en)
TW (1) TW200745100A (en)
WO (1) WO2006108879A2 (en)
ZA (1) ZA200708811B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027887A1 (en) 2000-05-31 2001-12-13 Jenapharm Gmbh Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds
US7534780B2 (en) 2004-05-21 2009-05-19 Bayer Schering Pharma Aktiengesellschaft Estradiol prodrugs
DE102005057421A1 (en) * 2005-11-30 2007-05-31 Bayer Schering Pharma Ag New heteroaromatic sulfonamide prodrugs, useful for delivering e.g. antimalarials and steroids for e.g. fertility control or hormone replacement therapy
US7981929B2 (en) 2007-03-16 2011-07-19 Sequoia Pharmaceuticals, Inc. Benzofuran derived HIV protease inhibitors
AR069539A1 (en) * 2007-07-25 2010-02-03 Tibotec Pharm Ltd ADVANCES REGARDING FORMULATIONS OF TABLETS AGAINST HIV
JP5745855B2 (en) * 2007-11-28 2015-07-08 セコイア、ファーマシューティカルズ、インコーポレイテッドＳｅｑｕｏｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Compositions and methods for inhibiting cytochrome P450 2D6
UA103013C2 (en) * 2007-12-06 2013-09-10 Тиботек Фармасьютикелз Amide compounds as boosters of antivirals
EP2231628B1 (en) * 2008-01-04 2015-10-28 Gilead Sciences, Inc. Inhibitors of cytochrome p450
US20110195940A1 (en) * 2008-09-17 2011-08-11 Nektar Therapeutics Protease Inhibitors Having Enhanced Features
BRPI0920809A2 (en) * 2008-10-07 2016-07-12 Tibotec Pharm Ltd amide compounds as antiviral boosters
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
US20110155359A1 (en) * 2009-12-16 2011-06-30 E. I. Du Pont De Nemours And Company Hollow structures and associated method for conveying refrigerant fluids
EP2528923B1 (en) 2010-01-28 2014-07-30 Mapi Pharma Limited Process for the preparation of darunavir and darunavir intermediates
AR080374A1 (en) 2010-03-05 2012-04-04 Sanofi Aventis PROCEDURE FOR THE PREPARATION OF 2- (CYCLOHEXILMETIL) -N- (2 - ((2S) -1-METHYLPIRROLIDIN-2-IL) ETIL) - 1,2,3,4-TETRAHYDROISOQUINOLIN-7- SULFONAMIDE
CN102080122B (en) * 2010-11-26 2013-04-10 吉林大学 Detecting method for simultaneously measuring metabolic products of probe medicines of five CYP450 enzymes
CN102175804B (en) * 2010-12-30 2013-06-05 吉林大学 Absolute quantitative method for biomass spectra of CYP450 enzyme hypotypes
CN104540813A (en) * 2012-06-27 2015-04-22 默沙东公司 Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug
WO2014000178A1 (en) 2012-06-27 2014-01-03 Merck Sharp & Dohme Corp. Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug
WO2014194519A1 (en) 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug
WO2015070366A1 (en) 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
WO2015070367A1 (en) * 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
CN111202723A (en) * 2020-02-15 2020-05-29 江苏艾立康药业股份有限公司 Darunavir inhalation dry powder pharmaceutical composition and preparation method thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037157A (en) * 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
AU2010299A (en) 1997-12-24 1999-07-19 Vertex Pharmaceuticals Incorporated Prodrugs os aspartyl protease inhibitors
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
WO1999033795A1 (en) 1997-12-24 1999-07-08 Vertex Pharmaceuticals Incorporated Prodrugs of aspartyl protease inhibitors
EE05385B1 (en) 2001-02-14 2011-02-15 Tibotec�Pharmaceuticals�Ltd. Broad-spectrum Á2- (Substituted Áamino) Benzothiazole Sulphonamides ÁkuiÁHIVÁProtease Inhibitors, Methods of Preparation, and UseUnited Pharmaceutical Formulations
AU2002310818B2 (en) * 2001-05-11 2007-12-13 Tibotec Pharmaceuticals Ltd. Broadspectrum 2-amino-benzoxazole sulfonamide HIV protease inhibitors
EP1304404A1 (en) 2001-10-17 2003-04-23 Milliken Europe N.V. Reinforcement fabrics having at least two reinforcement directions
AR037797A1 (en) 2001-12-12 2004-12-01 Tibotec Pharm Ltd COMBINATION OF PROTEASA INHIBITORS DEPENDENTS OF CITOCROMO P450
TWI332956B (en) 2002-04-26 2010-11-11 Gilead Sciences Inc Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
DE602004004674T2 (en) * 2003-09-30 2007-11-22 Tibotec Pharmaceuticals Ltd. METHOD FOR PRODUCING BENZOXAZOLSULFONAMIDE COMPOUNDS AND INTERMEDIATE PRODUCTS THEREOF

Also Published As

Publication number Publication date
CA2604799A1 (en) 2006-10-19
JP2008535896A (en) 2008-09-04
TW200745100A (en) 2007-12-16
AU2006234335B2 (en) 2011-09-29
AU2006234335A1 (en) 2006-10-19
US20080287488A1 (en) 2008-11-20
WO2006108879A3 (en) 2008-01-10
AR053845A1 (en) 2007-05-23
CN101175491A (en) 2008-05-07
EP1874307A2 (en) 2008-01-09
CA2604799C (en) 2015-06-09
BRPI0608322A2 (en) 2009-12-29
US8557854B2 (en) 2013-10-15
EA200702242A1 (en) 2008-02-28
WO2006108879A2 (en) 2006-10-19
EA016340B1 (en) 2012-04-30
CN101175491B (en) 2011-07-27

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