ZA200707970B - Compositions of HSP60 peptides and viral antigens for vaccination and diagnosis - Google Patents

Compositions of HSP60 peptides and viral antigens for vaccination and diagnosis

Info

Publication number
ZA200707970B
ZA200707970B ZA200707970A ZA200707970A ZA200707970B ZA 200707970 B ZA200707970 B ZA 200707970B ZA 200707970 A ZA200707970 A ZA 200707970A ZA 200707970 A ZA200707970 A ZA 200707970A ZA 200707970 B ZA200707970 B ZA 200707970B
Authority
ZA
South Africa
Prior art keywords
vaccination
diagnosis
compositions
viral antigens
hsp60 peptides
Prior art date
Application number
ZA200707970A
Other languages
English (en)
Inventor
Irun R Cohen
Rager-Zisman Bracha
Porgador Angel
Herkel Johannes
Original Assignee
Yeda Res & Dev
B G Negev Technologies And App
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, B G Negev Technologies And App filed Critical Yeda Res & Dev
Publication of ZA200707970B publication Critical patent/ZA200707970B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6043—Heat shock proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200707970A 2005-03-14 2006-02-21 Compositions of HSP60 peptides and viral antigens for vaccination and diagnosis ZA200707970B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66101705P 2005-03-14 2005-03-14

Publications (1)

Publication Number Publication Date
ZA200707970B true ZA200707970B (en) 2008-11-26

Family

ID=36992117

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200707970A ZA200707970B (en) 2005-03-14 2006-02-21 Compositions of HSP60 peptides and viral antigens for vaccination and diagnosis

Country Status (7)

Country Link
US (3) US20080279878A1 (fr)
EP (2) EP1858548B1 (fr)
AU (1) AU2006224216B2 (fr)
CA (1) CA2601518A1 (fr)
ES (1) ES2389849T3 (fr)
WO (1) WO2006097914A2 (fr)
ZA (1) ZA200707970B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8414899B2 (en) * 2006-04-11 2013-04-09 Yeda Research And Development Co. Ltd. Vaccines comprising multimeric HSP60 peptide carriers
US9345753B2 (en) 2008-01-16 2016-05-24 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Vaccine for alzheimer's disease
GB201300684D0 (en) 2013-01-15 2013-02-27 Apitope Int Nv Peptide
PH12013000059A1 (en) * 2013-02-15 2016-12-12 Yu Gracia Fe Diagnosis and detection of dengue virus infection using chicken egg antibodies
CN103880962B (zh) * 2014-03-19 2016-01-06 国家纳米科学中心 融合蛋白及其编码基因和制备方法以及一种药物组合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4073943A (en) 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
NL8701163A (nl) 1986-09-09 1988-04-05 Nederlanden Staat Gebruik van een peptide voor de bereiding van preparaten voor het verlichten, het behandelen en de diagnose van autoimmuunziekten, in het bijzonder arthritische toestanden, verbindingen die met dit peptide verwant zijn, alsmede farmaceutische en diagnostische preparaten en testkits.
NL8703107A (nl) 1987-12-22 1989-07-17 Nederlanden Staat Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten.
US5114844A (en) 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus
US5736146A (en) * 1992-07-30 1998-04-07 Yeda Research And Development Co. Ltd. Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
US5961970A (en) 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US5869058A (en) 1994-05-25 1999-02-09 Yeda Research And Development Co. Ltd. Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines
IL109790A0 (en) * 1994-05-25 1994-08-26 Yeda Res & Dev Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines
US7790158B2 (en) * 2001-09-25 2010-09-07 The Regents Of The University Of California Methods for epitope-specific and cytokine/anticytokine combination immunotherapies
WO2002062959A2 (fr) * 2001-02-05 2002-08-15 Stressgen Biotechnologies Corp. Traitement du virus de l'hepatite b
AU2003263853A1 (en) * 2002-08-16 2004-03-03 Board Of Regents The University Of Texas System Compositions and methods related to flavivirus envelope protein domain iii antigens

Also Published As

Publication number Publication date
EP2402022B1 (fr) 2014-10-29
WO2006097914A3 (fr) 2007-01-04
EP2402022A2 (fr) 2012-01-04
US20080279878A1 (en) 2008-11-13
US20110256165A1 (en) 2011-10-20
EP2402022A3 (fr) 2012-04-25
EP1858548A2 (fr) 2007-11-28
AU2006224216A1 (en) 2006-09-21
US8652439B2 (en) 2014-02-18
AU2006224216B2 (en) 2011-12-08
EP1858548B1 (fr) 2012-06-20
EP1858548A4 (fr) 2009-03-11
ES2389849T3 (es) 2012-11-02
CA2601518A1 (fr) 2006-09-21
WO2006097914A2 (fr) 2006-09-21
US20140120126A1 (en) 2014-05-01

Similar Documents

Publication Publication Date Title
EP2089053A4 (fr) Compositions vaccinales a base de proteine de fusion de l'antigene hpv et utilisations de celles-ci
HRP20170024T1 (hr) Antigeni peptidi gm-csf i protutijela protiv gm-csf
HK1211606A1 (en) Identification of tumor-associated antigens for diagnosis and therapy
ZA200810456B (en) Lyophilized formulations of anti-EGFR antibodies
EP1984405A4 (fr) Antigenes de la grippe, compositions de vaccins et procedes associees
ZA201002160B (en) Human gm-csf antigen binding proteins
IL193397A0 (en) Hpv antigens, vaccine compositions, and related methods
EP1948227A4 (fr) Vaccin a antigene combinatoire contre la grippe
EP2006377A4 (fr) Nouveaux peptides antigènes tumoraux
AU2003246373A8 (en) Recombinant measles viruses expressing epitopes of antigens of rna viruses - use for the preparation of vaccine compositions
PL1890720T3 (pl) Kompozycje farmaceutyczne zawierające peptydy pochodzące z kazeiny i sposoby ich stosowania
IL205398A0 (en) New antibodies specific of the ?? - amyloid peptides and their uses as diagnostic agents or drugs
EP1934335A4 (fr) Particules virus mosaique du tabac modifiées utilisées comme supports pour la disposition d'antigènes protéiques pour des applications de vaccins
HK1219052A1 (zh) 針對典型性豬瘟病毒的嵌合疫苗抗原
ZA200707970B (en) Compositions of HSP60 peptides and viral antigens for vaccination and diagnosis
ZA200805198B (en) Pro-apoptotic bacteria and compositions for delivery and expression of antigens
EP1871786A4 (fr) Vaccin peptidique contre la grippe
ZA201101743B (en) Vaccine comprising protein nmbo964 from meisseria meningitidis
ZA200803664B (en) Chimeric antigens and vaccines
IL185932A0 (en) Compositions of hsp60 peptides and viral antigers for vaccination and diagnosis
EP2024538A4 (fr) Compositions et methodes pour identifier des antigenes
ZA200710374B (en) Pharmaceutical compositions comprising casein derived peptides and methods of use thereof
IL185772A0 (en) Antigen specific lymphocytes, compositions thereof, and methods for isolation and preparation thereof
IL222485A (en) Medical preparations that contain peptide-derived peptides and methods for their use
IL187120A0 (en) Pharmaceutical compositions comprising casein derived peptides and methods of use thereof