ZA200505423B - Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin - Google Patents
Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietinInfo
- Publication number
- ZA200505423B ZA200505423B ZA200505423A ZA200505423A ZA200505423B ZA 200505423 B ZA200505423 B ZA 200505423B ZA 200505423 A ZA200505423 A ZA 200505423A ZA 200505423 A ZA200505423 A ZA 200505423A ZA 200505423 B ZA200505423 B ZA 200505423B
- Authority
- ZA
- South Africa
- Prior art keywords
- long acting
- tissue protective
- protective activity
- maintain tissue
- endogenous erythropoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Analytical Chemistry (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40902002P | 2002-09-09 | 2002-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200505423B true ZA200505423B (en) | 2008-08-27 |
Family
ID=31978712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200505423A ZA200505423B (en) | 2002-09-09 | 2003-09-09 | Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1545586A4 (en) |
JP (1) | JP2006511468A (en) |
KR (1) | KR20050083682A (en) |
CN (2) | CN101371920A (en) |
AU (1) | AU2003273297A1 (en) |
BR (1) | BR0314152A (en) |
CA (1) | CA2497960A1 (en) |
EA (1) | EA007812B1 (en) |
IL (1) | IL174178A0 (en) |
IS (1) | IS7731A (en) |
MX (1) | MXPA05002617A (en) |
NO (1) | NO20051714L (en) |
PL (1) | PL375741A1 (en) |
WO (1) | WO2004022577A2 (en) |
ZA (1) | ZA200505423B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
WO2006061853A2 (en) * | 2004-12-10 | 2006-06-15 | Serum Institute Of India Limited | Novel erythropoietic compounds and a process for producing erythropoietic compounds |
TWI376234B (en) | 2005-02-01 | 2012-11-11 | Msd Oss Bv | Conjugates of a polypeptide and an oligosaccharide |
DK2594279T3 (en) | 2005-08-05 | 2018-01-08 | Araim Pharmaceuticals Inc | Tissue-protecting peptides and uses thereof |
CN111346213A (en) | 2008-01-22 | 2020-06-30 | 阿拉伊姆药品公司 | Tissue protective peptides and peptide analogs for the prevention and treatment of diseases and disorders associated with tissue damage |
CN101671388B (en) * | 2008-09-09 | 2013-01-02 | 曹国栋 | Blood brain barrier penetrable erythropoietin (EPO) and application thereof |
RU2475273C1 (en) * | 2012-04-02 | 2013-02-20 | Юлия Николаевна Козлова | Method of obtaining polymeric cement of medical purpose |
CN102746405B (en) * | 2012-07-24 | 2013-08-21 | 深圳赛保尔生物药业有限公司 | Continuous pegylation reaction method for recombinant human erythropoietin (EPO) |
RU2664588C2 (en) * | 2015-11-05 | 2018-08-21 | Закрытое Акционерное Общество "Биокад" | Extended factor of human erythropoiesis and a therapeutic agent based thereon |
JP2019523633A (en) | 2016-04-29 | 2019-08-29 | アライム ファーマシューティカルズ,インコーポレーテッド | Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage |
CN112741895A (en) * | 2021-01-19 | 2021-05-04 | 中国人民解放军陆军军医大学 | Application of EPO analog in preparing medicament for treating sepsis |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2291B1 (en) * | 1999-07-02 | 2005-09-12 | اف . هوفمان لاروش ايه جي | Erythopintin derivatives |
JP5022551B2 (en) * | 2000-04-21 | 2012-09-12 | アムジエン・インコーポレーテツド | Methods and compositions for the prevention and treatment of anemia |
HU230874B1 (en) * | 2000-05-15 | 2018-11-29 | F. Hoffmann-La Roche Ag | Liquid pharmaceutical compositions stable at room temperature which comprising a pegylated human erythropoietin protein |
-
2003
- 2003-09-09 JP JP2004534745A patent/JP2006511468A/en not_active Withdrawn
- 2003-09-09 EA EA200500473A patent/EA007812B1/en not_active IP Right Cessation
- 2003-09-09 EP EP03755796A patent/EP1545586A4/en not_active Withdrawn
- 2003-09-09 CN CNA2008101490873A patent/CN101371920A/en active Pending
- 2003-09-09 BR BR0314152-7A patent/BR0314152A/en not_active IP Right Cessation
- 2003-09-09 CA CA002497960A patent/CA2497960A1/en not_active Withdrawn
- 2003-09-09 PL PL03375741A patent/PL375741A1/en not_active Application Discontinuation
- 2003-09-09 WO PCT/US2003/028073 patent/WO2004022577A2/en active Application Filing
- 2003-09-09 CN CNA038249154A patent/CN1729015A/en active Pending
- 2003-09-09 AU AU2003273297A patent/AU2003273297A1/en not_active Abandoned
- 2003-09-09 KR KR1020057004045A patent/KR20050083682A/en not_active Application Discontinuation
- 2003-09-09 ZA ZA200505423A patent/ZA200505423B/en unknown
- 2003-09-09 MX MXPA05002617A patent/MXPA05002617A/en unknown
-
2005
- 2005-03-08 IS IS7731A patent/IS7731A/en unknown
- 2005-04-06 NO NO20051714A patent/NO20051714L/en not_active Application Discontinuation
-
2006
- 2006-03-08 IL IL174178A patent/IL174178A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2003273297A1 (en) | 2004-03-29 |
CA2497960A1 (en) | 2004-03-18 |
IS7731A (en) | 2005-03-08 |
KR20050083682A (en) | 2005-08-26 |
WO2004022577A3 (en) | 2004-09-16 |
CN1729015A (en) | 2006-02-01 |
EP1545586A2 (en) | 2005-06-29 |
WO2004022577A2 (en) | 2004-03-18 |
BR0314152A (en) | 2005-07-12 |
JP2006511468A (en) | 2006-04-06 |
IL174178A0 (en) | 2006-08-01 |
EP1545586A4 (en) | 2007-09-26 |
PL375741A1 (en) | 2005-12-12 |
NO20051714L (en) | 2005-06-06 |
CN101371920A (en) | 2009-02-25 |
AU2003273297A8 (en) | 2004-03-29 |
MXPA05002617A (en) | 2005-09-08 |
EA007812B1 (en) | 2007-02-27 |
EA200500473A1 (en) | 2005-10-27 |
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