ZA200406579B

ZA200406579B - Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation, as well as novel processes for preparing atorvastatin hemi-calcium forms I, VIII and IX.

Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation, as well as novel processes for preparing atorvastatin hemi-calcium forms I, VIII and IX. Download PDF

Info

Publication number: ZA200406579B
Authority: ZA; South Africa
Prior art keywords: calcium; atorvastatin hemi; characteristic; solid crystalline; solvates
Prior art date: 2002-02-15

Application number

ZA200406579A

Other languages

English (en)

Inventor

Limor Tessler

Judith Aronhime

Revital Lifschitz-Liron

Dalia Maidan-Hanoch

Nir Hasson

Original Assignee

Teva Pharma

Priority date

2002-02-15

Filing date

2004-08-18

Publication date

2005-11-30

2004-08-18 Application filed by Teva Pharma filed Critical Teva Pharma

2005-11-30 Publication of ZA200406579B publication Critical patent/ZA200406579B/en

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FQCKMBLVYCEXJB-MNSAWQCASA-L atorvastatin calcium Chemical compound [Ca+2].C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1.C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 FQCKMBLVYCEXJB-MNSAWQCASA-L 0.000 title claims description 153
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