ZA200300314B - Polymer-modified synthetic proteins. - Google Patents

Polymer-modified synthetic proteins.

Info

Publication number
ZA200300314B
ZA200300314B ZA200300314A ZA200300314A ZA200300314B ZA 200300314 B ZA200300314 B ZA 200300314B ZA 200300314 A ZA200300314 A ZA 200300314A ZA 200300314 A ZA200300314 A ZA 200300314A ZA 200300314 B ZA200300314 B ZA 200300314B
Authority
ZA
South Africa
Prior art keywords
polymer
modified synthetic
synthetic proteins
proteins
modified
Prior art date
Application number
ZA200300314A
Inventor
Gerd G Kochendoerfer
Paolo Botti
James A Bradburne
Shiah-Yun Chen
Sonya Cressman
Christie L Hunter
Stephen B H Kent
Donald W Low
Jill G Wilken
Original Assignee
Gryphon Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gryphon Therapeutics Inc filed Critical Gryphon Therapeutics Inc
Publication of ZA200300314B publication Critical patent/ZA200300314B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/80Cytochromes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
ZA200300314A 2000-09-08 2003-01-13 Polymer-modified synthetic proteins. ZA200300314B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23133900P 2000-09-08 2000-09-08

Publications (1)

Publication Number Publication Date
ZA200300314B true ZA200300314B (en) 2004-02-04

Family

ID=22868813

Family Applications (3)

Application Number Title Priority Date Filing Date
ZA200300315A ZA200300315B (en) 2000-09-08 2003-01-13 "Pseudo" -native chemical ligation.
ZA200300314A ZA200300314B (en) 2000-09-08 2003-01-13 Polymer-modified synthetic proteins.
ZA200300659A ZA200300659B (en) 2000-09-08 2003-01-24 Synthetic erythropoiesis stimulating proteins.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200300315A ZA200300315B (en) 2000-09-08 2003-01-13 "Pseudo" -native chemical ligation.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200300659A ZA200300659B (en) 2000-09-08 2003-01-24 Synthetic erythropoiesis stimulating proteins.

Country Status (12)

Country Link
EP (1) EP1315738A4 (en)
JP (2) JP2004508383A (en)
KR (1) KR20030061785A (en)
CN (1) CN1452632A (en)
AU (2) AU2001288937B2 (en)
BR (2) BR0113579A (en)
CA (1) CA2412298A1 (en)
ES (1) ES2360203T3 (en)
IL (1) IL154015A0 (en)
MX (1) MXPA03001450A (en)
WO (1) WO2002020557A1 (en)
ZA (3) ZA200300315B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2487342A1 (en) * 2002-06-10 2003-12-24 Geneprot, Inc. Post-cleavage sulfur deprotection for convergent protein synthesis by chemical ligation
WO2004061094A1 (en) 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Water-soluble thioester and selenoester compounds and methods for making and using the same
WO2007049635A1 (en) * 2005-10-25 2007-05-03 Riken Process for production of peptide thioester
WO2011017837A1 (en) * 2009-08-12 2011-02-17 Xuechen Li Native chemical ligation at serine and threonine sites
FR2952058B1 (en) * 2009-10-29 2013-10-04 Centre Nat Rech Scient PROCESS FOR NATIVE LIGATION OF POLYPEPTIDES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184344B1 (en) * 1995-05-04 2001-02-06 The Scripps Research Institute Synthesis of proteins by native chemical ligation
US6307018B1 (en) * 1996-12-24 2001-10-23 The Scripps Research Institute General chemical ligation
WO1998028434A1 (en) * 1996-12-24 1998-07-02 The Scripps Research Institute General chemical ligation

Also Published As

Publication number Publication date
JP2008150393A (en) 2008-07-03
MXPA03001450A (en) 2004-12-13
IL154015A0 (en) 2003-07-31
ZA200300315B (en) 2004-02-04
AU8893701A (en) 2002-03-22
CN1452632A (en) 2003-10-29
BR0113623A (en) 2004-06-22
CA2412298A1 (en) 2002-03-14
EP1315738A4 (en) 2006-06-07
ZA200300659B (en) 2004-03-05
BR0113579A (en) 2003-06-17
AU2001288937B2 (en) 2005-04-28
ES2360203T3 (en) 2011-06-01
KR20030061785A (en) 2003-07-22
EP1315738A1 (en) 2003-06-04
WO2002020557A1 (en) 2002-03-14
JP2004508383A (en) 2004-03-18

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