ZA200209954B - Thiazolidinedione salt for treatment of diabetes mellitus. - Google Patents
Thiazolidinedione salt for treatment of diabetes mellitus. Download PDFInfo
- Publication number
- ZA200209954B ZA200209954B ZA200209954A ZA200209954A ZA200209954B ZA 200209954 B ZA200209954 B ZA 200209954B ZA 200209954 A ZA200209954 A ZA 200209954A ZA 200209954 A ZA200209954 A ZA 200209954A ZA 200209954 B ZA200209954 B ZA 200209954B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrobromide
- solvate
- methyl
- amino
- ethoxy
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title claims description 20
- 238000011282 treatment Methods 0.000 title claims description 11
- 150000001467 thiazolidinediones Chemical class 0.000 title description 3
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- 239000012453 solvate Substances 0.000 claims description 31
- 150000001875 compounds Chemical class 0.000 claims description 28
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims description 9
- -1 compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine- 2,4-dione hydrobromide Chemical class 0.000 claims description 8
- 229910000042 hydrogen bromide Inorganic materials 0.000 claims description 8
- 238000000634 powder X-ray diffraction Methods 0.000 claims description 8
- 238000011321 prophylaxis Methods 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
- 238000002844 melting Methods 0.000 claims description 6
- 230000008018 melting Effects 0.000 claims description 6
- 239000008194 pharmaceutical composition Substances 0.000 claims description 5
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 claims description 4
- MSOPDKKENJARPF-UHFFFAOYSA-N 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrobromide Chemical compound Br.C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O MSOPDKKENJARPF-UHFFFAOYSA-N 0.000 claims description 4
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0014006.1A GB0014006D0 (en) | 2000-06-08 | 2000-06-08 | Novel pharmaceutical |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200209954B true ZA200209954B (en) | 2003-10-10 |
Family
ID=9893257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200209954A ZA200209954B (en) | 2000-06-08 | 2002-12-09 | Thiazolidinedione salt for treatment of diabetes mellitus. |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1296980A1 (no) |
| JP (1) | JP2003535862A (no) |
| KR (1) | KR20030007918A (no) |
| CN (1) | CN1443186A (no) |
| AP (1) | AP2002002673A0 (no) |
| AU (1) | AU2001264078A1 (no) |
| BG (1) | BG107357A (no) |
| BR (1) | BR0111536A (no) |
| CA (1) | CA2411065A1 (no) |
| CZ (1) | CZ20023966A3 (no) |
| DZ (1) | DZ3382A1 (no) |
| EA (1) | EA200300005A1 (no) |
| GB (1) | GB0014006D0 (no) |
| HU (1) | HUP0301137A3 (no) |
| IL (1) | IL153279A0 (no) |
| MA (1) | MA25753A1 (no) |
| MX (1) | MXPA02012100A (no) |
| NO (1) | NO20025883L (no) |
| OA (1) | OA12284A (no) |
| PL (1) | PL360592A1 (no) |
| SK (1) | SK17142002A3 (no) |
| WO (1) | WO2001094344A1 (no) |
| ZA (1) | ZA200209954B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE39384E1 (en) | 1993-09-01 | 2006-11-07 | Smithkline Beecham P.L.C. | Substituted thiazolidinedione derivatives |
| DE102005034406A1 (de) * | 2005-07-22 | 2007-02-01 | Ratiopharm Gmbh | Neue Salze von Rosiglitazon |
| WO2008091624A2 (en) * | 2007-01-22 | 2008-07-31 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of rosiglitazone hydrobromide and processes for preparation thereof |
| EP1956018A1 (de) * | 2007-02-06 | 2008-08-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verfahren zur Herstellung eines Benzimidazolderivats |
| US20100056583A1 (en) * | 2008-08-21 | 2010-03-04 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of rosiglitazone hydrobromide and processes for their preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
-
2000
- 2000-06-08 GB GBGB0014006.1A patent/GB0014006D0/en not_active Ceased
-
2001
- 2001-06-08 DZ DZ013382A patent/DZ3382A1/xx active
- 2001-06-08 EP EP01938400A patent/EP1296980A1/en not_active Withdrawn
- 2001-06-08 AU AU2001264078A patent/AU2001264078A1/en not_active Abandoned
- 2001-06-08 WO PCT/GB2001/002567 patent/WO2001094344A1/en not_active Application Discontinuation
- 2001-06-08 EA EA200300005A patent/EA200300005A1/ru unknown
- 2001-06-08 CA CA002411065A patent/CA2411065A1/en not_active Abandoned
- 2001-06-08 AP APAP/P/2002/002673A patent/AP2002002673A0/en unknown
- 2001-06-08 CZ CZ20023966A patent/CZ20023966A3/cs unknown
- 2001-06-08 IL IL15327901A patent/IL153279A0/xx unknown
- 2001-06-08 JP JP2002501893A patent/JP2003535862A/ja active Pending
- 2001-06-08 PL PL36059201A patent/PL360592A1/xx not_active Application Discontinuation
- 2001-06-08 CN CN01813190A patent/CN1443186A/zh active Pending
- 2001-06-08 MX MXPA02012100A patent/MXPA02012100A/es unknown
- 2001-06-08 HU HU0301137A patent/HUP0301137A3/hu unknown
- 2001-06-08 KR KR1020027016721A patent/KR20030007918A/ko not_active Application Discontinuation
- 2001-06-08 SK SK1714-2002A patent/SK17142002A3/sk not_active Application Discontinuation
- 2001-06-08 BR BR0111536-7A patent/BR0111536A/pt not_active IP Right Cessation
- 2001-06-08 OA OA1200200370A patent/OA12284A/en unknown
-
2002
- 2002-12-04 MA MA26933A patent/MA25753A1/fr unknown
- 2002-12-05 BG BG107357A patent/BG107357A/bg unknown
- 2002-12-06 NO NO20025883A patent/NO20025883L/no not_active Application Discontinuation
- 2002-12-09 ZA ZA200209954A patent/ZA200209954B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0014006D0 (en) | 2000-08-02 |
| OA12284A (en) | 2003-11-10 |
| PL360592A1 (en) | 2004-09-20 |
| EA200300005A1 (ru) | 2003-04-24 |
| HUP0301137A2 (hu) | 2003-08-28 |
| WO2001094344A1 (en) | 2001-12-13 |
| IL153279A0 (en) | 2003-07-06 |
| HUP0301137A3 (en) | 2005-04-28 |
| JP2003535862A (ja) | 2003-12-02 |
| SK17142002A3 (sk) | 2003-10-07 |
| CN1443186A (zh) | 2003-09-17 |
| CZ20023966A3 (cs) | 2003-04-16 |
| BR0111536A (pt) | 2003-07-01 |
| MA25753A1 (fr) | 2003-04-01 |
| DZ3382A1 (fr) | 2001-12-13 |
| CA2411065A1 (en) | 2001-12-13 |
| BG107357A (bg) | 2003-08-29 |
| AP2002002673A0 (en) | 2002-12-31 |
| MXPA02012100A (es) | 2003-04-25 |
| AU2001264078A1 (en) | 2001-12-17 |
| KR20030007918A (ko) | 2003-01-23 |
| EP1296980A1 (en) | 2003-04-02 |
| NO20025883D0 (no) | 2002-12-06 |
| NO20025883L (no) | 2003-02-03 |
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