ZA200207807B - Stable and efficacious soft solid product. - Google Patents
Stable and efficacious soft solid product. Download PDFInfo
- Publication number
- ZA200207807B ZA200207807B ZA200207807A ZA200207807A ZA200207807B ZA 200207807 B ZA200207807 B ZA 200207807B ZA 200207807 A ZA200207807 A ZA 200207807A ZA 200207807 A ZA200207807 A ZA 200207807A ZA 200207807 B ZA200207807 B ZA 200207807B
- Authority
- ZA
- South Africa
- Prior art keywords
- antiperspirant
- weight
- composition according
- group
- dimethicone
- Prior art date
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- 239000012265 solid product Substances 0.000 title description 3
- 239000000203 mixture Substances 0.000 claims description 75
- 230000001166 anti-perspirative effect Effects 0.000 claims description 45
- 239000003213 antiperspirant Substances 0.000 claims description 45
- 229920001296 polysiloxane Polymers 0.000 claims description 28
- -1 polyethylene Polymers 0.000 claims description 27
- 239000003974 emollient agent Substances 0.000 claims description 20
- 239000002781 deodorant agent Substances 0.000 claims description 18
- 239000007787 solid Substances 0.000 claims description 18
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 14
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 14
- 239000004698 Polyethylene Substances 0.000 claims description 12
- 229940008099 dimethicone Drugs 0.000 claims description 12
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 12
- 229920000573 polyethylene Polymers 0.000 claims description 12
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical group C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 10
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- 235000019388 lanolin Nutrition 0.000 claims description 9
- 239000003205 fragrance Substances 0.000 claims description 8
- 229940039717 lanolin Drugs 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 8
- 229920006395 saturated elastomer Polymers 0.000 claims description 8
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 7
- 229920006037 cross link polymer Polymers 0.000 claims description 7
- 229940086555 cyclomethicone Drugs 0.000 claims description 7
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 7
- 239000000194 fatty acid Substances 0.000 claims description 7
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- 150000004665 fatty acids Chemical class 0.000 claims description 7
- 239000003921 oil Substances 0.000 claims description 7
- DLAHAXOYRFRPFQ-UHFFFAOYSA-N dodecyl benzoate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC=CC=C1 DLAHAXOYRFRPFQ-UHFFFAOYSA-N 0.000 claims description 6
- 150000002148 esters Chemical class 0.000 claims description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 6
- 229940057874 phenyl trimethicone Drugs 0.000 claims description 5
- LINXHFKHZLOLEI-UHFFFAOYSA-N trimethyl-[phenyl-bis(trimethylsilyloxy)silyl]oxysilane Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C1=CC=CC=C1 LINXHFKHZLOLEI-UHFFFAOYSA-N 0.000 claims description 5
- NRTKYSGFUISGRQ-UHFFFAOYSA-N (3-heptanoyloxy-2,2-dimethylpropyl) heptanoate Chemical compound CCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCC NRTKYSGFUISGRQ-UHFFFAOYSA-N 0.000 claims description 4
- 125000006743 (C1-C60) alkyl group Chemical group 0.000 claims description 4
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
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- 125000002947 alkylene group Chemical group 0.000 claims description 4
- 239000004599 antimicrobial Substances 0.000 claims description 4
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- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
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- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 2
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 229940116224 behenate Drugs 0.000 claims description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-M behenate Chemical compound CCCCCCCCCCCCCCCCCCCCCC([O-])=O UKMSUNONTOPOIO-UHFFFAOYSA-M 0.000 claims description 2
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- 150000003377 silicon compounds Chemical class 0.000 claims description 2
- GVPDNFYOFKBFEN-UHFFFAOYSA-N trimethyl(octadecoxy)silane Chemical compound CCCCCCCCCCCCCCCCCCO[Si](C)(C)C GVPDNFYOFKBFEN-UHFFFAOYSA-N 0.000 claims description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims description 2
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- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
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- 239000000463 material Substances 0.000 description 20
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- 239000000126 substance Substances 0.000 description 4
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- WYANSMZYIOPJFV-UHFFFAOYSA-L aluminum;2-aminoacetic acid;zirconium(4+);chloride;hydroxide;hydrate Chemical compound O.[OH-].[Al+3].[Cl-].[Zr+4].NCC(O)=O WYANSMZYIOPJFV-UHFFFAOYSA-L 0.000 description 3
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- 235000019197 fats Nutrition 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000003981 vehicle Substances 0.000 description 3
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- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 2
- 229940058020 2-amino-2-methyl-1-propanol Drugs 0.000 description 2
- KEIDIOZOTSZXPK-UHFFFAOYSA-N 4-methylpentyl decanoate Chemical compound CCCCCCCCCC(=O)OCCCC(C)C KEIDIOZOTSZXPK-UHFFFAOYSA-N 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 239000004471 Glycine Substances 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
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- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 description 2
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- SSZBUIDZHHWXNJ-UHFFFAOYSA-N palmityl stearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC SSZBUIDZHHWXNJ-UHFFFAOYSA-N 0.000 description 2
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- CFOQKXQWGLAKSK-KTKRTIGZSA-N (13Z)-docosen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCCO CFOQKXQWGLAKSK-KTKRTIGZSA-N 0.000 description 1
- WFXHUBZUIFLWCV-UHFFFAOYSA-N (2,2-dimethyl-3-octanoyloxypropyl) octanoate Chemical compound CCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCC WFXHUBZUIFLWCV-UHFFFAOYSA-N 0.000 description 1
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- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical class ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 1
- 229940100554 isononyl isononanoate Drugs 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 229940093629 isopropyl isostearate Drugs 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- 229940089456 isopropyl stearate Drugs 0.000 description 1
- 229940060384 isostearyl isostearate Drugs 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940078812 myristyl myristate Drugs 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 150000004767 nitrides Chemical class 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 1
- YPMOZWCBANATQH-UHFFFAOYSA-N octyl 7-methyloctanoate Chemical compound CCCCCCCCOC(=O)CCCCCC(C)C YPMOZWCBANATQH-UHFFFAOYSA-N 0.000 description 1
- IIGMITQLXAGZTL-UHFFFAOYSA-N octyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCC IIGMITQLXAGZTL-UHFFFAOYSA-N 0.000 description 1
- 229940073665 octyldodecyl myristate Drugs 0.000 description 1
- 150000002888 oleic acid derivatives Chemical class 0.000 description 1
- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- ADGFKRMKSIAMAI-UHFFFAOYSA-L oxygen(2-);zirconium(4+);chloride;hydroxide Chemical compound [OH-].[O-2].[Cl-].[Zr+4] ADGFKRMKSIAMAI-UHFFFAOYSA-L 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000003348 petrochemical agent Substances 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- NEOZOXKVMDBOSG-UHFFFAOYSA-N propan-2-yl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C NEOZOXKVMDBOSG-UHFFFAOYSA-N 0.000 description 1
- ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229910052990 silicon hydride Inorganic materials 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- PZTAGFCBNDBBFZ-UHFFFAOYSA-N tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCCCC1CO PZTAGFCBNDBBFZ-UHFFFAOYSA-N 0.000 description 1
- DZKXJUASMGQEMA-UHFFFAOYSA-N tetradecyl tetradecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCC DZKXJUASMGQEMA-UHFFFAOYSA-N 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- GAWWVVGZMLGEIW-GNNYBVKZSA-L zinc ricinoleate Chemical compound [Zn+2].CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O.CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O GAWWVVGZMLGEIW-GNNYBVKZSA-L 0.000 description 1
- 229940100530 zinc ricinoleate Drugs 0.000 description 1
Description
STABLE AND EFFICACIOUS SOFT SOLID PRODUCT
Field of the Invention ‘ This invention relates to soft solid products made as suspensions and suitable for use as antiperspirants and/or deodorants. ra
IH
There is 2 continuing trend to develop new and superior cosmetic compositions especially for the reduction and/or elimination of wetness and/or odor under the arms.
Particular efforts include developing lower residue products especially with improved efficacy and aesthetics. Various product forms have included sticks (especially gel/sticks), gels, soft solids, roll-ons, aerosols and creams. Of these various forms the sticks, gels, soft solids creams and roll-ons ‘are made with a liquid base material incorporating a solidifying agent and/or gelling agent and/or thickening agent.
Generally, these forms include a solution of the cosmetically active ingredient in a suitable vehicle, a suspension of the active ingredient in a carrier vehicle, or a multiphasic dispersion or emulsion in which a solution of the active ingredient is dispersed or suspended in some continuous phase or in which the solubilized active ingredient constitutes the continuous phase.
A variety of soft-solid formulations are known. These include formulations made with the following ingredients: (a) clay thickening agent and an activator for the clay: for example, U.S. Patent
Number 5,019,375 to Tanner et al; and U.S. Patent Number 4,526,780 to Marschner et al; (b) particulate thickening agents such as fumed silica: for example, U.S. Patent
Number 5,069,897 to Orr; and U. S. Patent Number 4,937,069 to Shin; (c) selected volatile and/or non-volatile alkylmethylsiloxanes such as those including a structuring wax: for example, U.S. Patent Number 5,225,188 to Abrutyn et al; and PCT applications WO 97/16161 and 16162 both of which are assigned to
Unilever PLC; and (d) triglyceride gellants such as the glyceryl tribehenate described in U.S. Patent
Number 5,718,890 to Putnam et al. ) The use of a class of compositions known as silicone elastomers in cosmetic " compositions has shown some interesting results. PCT case WO 97/44010 and ’ 35 . assigned to the same assignee as this application describes a silicone gel material made by combining (a) a volatile silicone material and (b) an organopolysiloxane material (or silicone elastomer) as a gelling agent wherein the organopolysiloxane material (silicone elastomer) can be a reaction product of a vinyl-terminated siloxane polymer and a silicon hydride cross-linking agent. Related technology is also disclosed in PCT case
WO 98/00097, WO 98/00104 and 98/00105 assigned to Unilever PLC on cross-linked non-emulsifying elastomers. ‘ 5 U.S. Patent 5,599,533 to Stepniewski et al assigned to Estee Lauder describes a , stable water-in-oil emulsion system formed with an organopolysiloxane elastomer, a vehicle in which the elastomer is dispersed or dispersible, a stabilizing agent , a - surfactant and an aqueous component. A commercial product known as “REVELATION” retexturizing complex for hands and chest sold by the same assignee contains a silicone gel material with an organopolysiloxane component and octamethylcyclotetrasiloxane. :
EP 0 787 758 Al teaches a method for solvent thickening by using a silicone latex having a plurality of crosslinked polysiloxane particles.
Another recent case assigned to the same assignee as this application is WO 99/51192 and U.S. Patent Application Serial Number 9/273152 which describes antiperspirant compositions with the use of broad categories of elastomers. Other examples of the use of elastomer type materials and/ or methods for processing such materials may be found in PCT cases WO 98/00097; WO 98/00104; WO 98/00105;
WO 98/18438; WO 98/42307 all of which are incorporated herein by reference.
Two major problems have been observed when the use of elastomer materials is included in soft solid formulations. The first problem is reduction in efficacy due to the formation of an occlusive elastomeric film which prevents the active from diffusing into the sweat duct. The second problem is the consistency of the product as evidenced by high viscosity and elastic behavior when applied to the surface of the skin. In order to reduce this high viscosity, emollients and solvents have to be added which may negatively impact efficacy of the deodorant and/or antiperspirant. It has been found . that the use of a selected type of elastomer in soft solid formulations in combination with polyethylene beads as described herein overcomes these problems.
Thus, it is an object of the invention to provide improved cosmetic compositions with the improvements as previously described and which are useful as antiperspirants and/or deodorants. These and other objects of the invention will be apparent from the following description of the invention.
Z 35
It has been found that an improved soft solid cosmetic product may be made as "a suspension formed with: (a) a dimethicone/vinyldimethicone crosspolymer composition made by reacting ‘ 5 (inthe presence of a platinum catalyst) a polymethylhydrogensiloxane with an alpha, > omega-divinylpolydimethy! siloxane for which the dimethicone/vinyldimethicone ! crosspolymer composition (1) is used at a concentration of 4-10% in cyclomethicone (particularly 4-7%, and, more particularly, 4-6.5%) (for example, where the cyclomethicone is a D4 ar D3 cyclomethicone), (2) has a refractive index in the range of 1.392-1.402 at 25 degrees C, and (3) has a viscosity in the range of 0.013- 1 X 10°
Pascal seconds; : (b) polyethylene beads having a density in the range of 0.91-0.98 grams/cm’ and a particle size in the range of 5-40 microns, wherein the polyethylene beads are used in an amount of at least 2% by weight based on the total weight of the composition; (c) a volatile silicone; (d) an emollient (which may also be a mixture of two or more emollients and which may include a non-volatile silicone); and (e) an effective amount of an antiperspirant active material to cause an antiperspirant and/or a deodorant effect. :
The soft solid antiperspirant and/or deodorant product of this invention is an opaque product which leaves little or no white residue when applied and which exhibits improved efficacy and stability as compared to other formulations with different types of elastomers. Reduction of sweat of at least 40% can be achieved with the compositions of the invention as compared to typical levels of 15% for other products.
The stable, high efficacy, low residue cosmetic compositions of this invention are made by combining: (a) 40-75% (particularly 45-60%, and, more particularly, 46-53%) of a volatile silicone (especially a D5 cyclomethicone);, (b) 0.1-20% (particularly 2-18% and, more particularly, 5-15%) of an emollient or a mixture of two or more emollients (for example, 0.1-5% (particularly 0.3-4.0%, more particularly 0.4-2.0% and even more particularly 0.4-1.5%) of a non- . volatile silicone such as phenyltrimethicone; or 1-12% C12- 15 alkyl benzoate); (©) 0.5-6% (on a solids basis) (particularly 1-6% and, more particularly, 2-5%) of ’ 35 the dimethicone/vinyldimethicone crosspolymer composition as described above; :
(d) 0.1-20% (particularlyl 0-20% to get an antiperspirant effect) of an antiperspirant active based on an anhydrous, buffer-free antiperspirant active; (&) 2-15% (particularly 2-10% and, more particularly, 2-8% ) of polyethylene beads having a particle size in the range of 5-40 microns and a density in the range of 0.91-0.98 g/cm’; . 3) 0-5% antimicrobial agent; and - 23) 0-5% fragrance; wherein all percents are in percents by weight based on the total weight of the composition unless otherwise indicated.
The silicone materials used in forming the compositions of the present invention may be selected from the group consisting of conventional cyclic and linear volatile and non-volatile silicones which act as a swelling agent for the suitable elastomer.
Ilustratively, and not by way of limitation, the volatile silicones are one or more members selected from the group consisting of cyclic polydimethylsiloxanes such as those represented by Formula I:
CH, 0], ct
Formula I where n is an integer with a value of 3-7, particularly 5-6. By volatile silicone material is meant a material that has a measurable vapor pressure at ambient temperature. For example, DC-245 fluid from Dow Corning Corporation (Midland, Michigan) is a type of cyclomethicone which can be used. These include a tetramer (or octylmethylcyclotetrasiloxane) and a pentamer (or decamethylcyclopentasiloxane).
The nonvolatile and volatile linear silicones are one or more members selected from the group consisting of linear polydimethylsiloxanes such as those represented by Formula
II:
CH, © CH; - SRO, - CH, | : v CH,
Formula II and t is selected so that the molecular weight ranges from 800-260,000 and the viscosity ranges from 5-600,000 centistokes, for example Dimethicone DC 200 from
Dow Corning.
Emollients are a known class of materials in this art, imparting a soothing effect ’ 5 to the skin. These are ingredients which help to maintain the soft, smooth, and pliable appearance of the skin. Emollients are also known to reduce whitening on the skin ’ and/or improve aesthetics. Examples of chemical classes from which suitable emollients can be found include: (a) fats and oils which are the glyceryl esters of fatty acids, or triglycerides, normally found in animal and plant tissues, including those which have been hydrogenated to reduce or eliminate unsaturation. Also included are synthetically prepared esters of glycerin and fatty acids. Isolated and purified fatty acids can be esterified with glycerin to yield mono-, di-, and triglycerides. These are relatively pure fats which differ only slightly from the fats and oils found in nature. The general structure may be represented by Formula III:
CH,-COOR!
I
—
Formula III wherein each of R, R?, and R® may be the. same or different and have a carbon chain length (saturated or unsaturated) of 7 to 30. Specific examples include peanut oil, sesame oil, avocado oil, coconut, cocoa butter, almond oil, safflower oil, com oil, cotton seed oil, castor oil, hydrogenated castor oil, olive oil, jojoba oil, cod liver oil, palm oil, soybean oil, wheat germ oil, linseed oil, and sunflower seed oil; ®) hydrocarbons which are a group of compounds containing only carbon and hydrogen. These are derived from petrochemicals. Their structures can vary widely and include aliphatic, alicyclic and aromatic compounds. Specific examples include paraffin, petrolatum, hydrogenated polyisobutene, and mineral oil. (©) esters which chemically, are the covalent compounds formed between acids and alcohols. Esters can be formed from almost all acids (carboxylic and inorganic) and any alcohol. Esters here are derived from carboxylic acids and an alcohol. The general structure would be R*CO-OR®. The chain length for R* and R® ’ 35 can vary from 7 to 30 and can be saturated or unsaturated, straight chained or branched.
Specific examples include isopropyl myristate, isopropyl palmitate, isopropyl stearate, ’ isopropyl isostearate, butyl stearate, octyl stearate, hexyl laurate, cetyl stearate, diisopropyl! adipate, isodecyl oleate, diisopropyl sebacate, isostearyl lactate, C,, ;5alkyl benzoates, myreth-3 myristate, dioctyl malate, neopentyl glycol diheptanoate, neopentyl glycol dioctanoate, dipropylene glycol dibenzoate, Cy, 5 alcohols lactate, isohexyl decanoate, isohexyl caprate, diethylene glycol dioctanoate, octyl isononanoate, } isodecyl octanoate, diethylene glycol diisononanoate, isononyl isononanoate, isostearyl isostearate, behenyl behenate, C ,, s alkyl fumarate, laureth-2 benzoate, propylene . , glycol isoceteth-3 acetate, propylene glycol ceteth-3 acetate, octyldodecyl myristate, cetyl ricinoleate, myristyl myristate. (@ saturated and unsaturated fatty acids which are the carboxylic acids obtained by hydrolysis of animal or vegetable fats and oils. These have general structure R®{COQOH with the R® group having a carbon chain length between 7 and 30, straight chain or branched. Specific examples include lauric, muyristic, palmitic, stearic, oleic, linoleic and behenic acid. (e) saturated and unsaturated fatty alcohols (including guerbet alcohols) with general structure R’"COH where R can be straight or branched and have carbon length of 7 to 30. Specific examples include lauryl, myristyl, cetyl, isocetyl, stearyl, isostearyl, oleyl, ricinoley! and erucyl alcohol; ® lanolin and its derivatives which are a complex esterified mixture of high molecular weight esters of (hydroxylated) fatty acids with aliphatic and alicyclic alcohols and sterols. General structures would include R*CH,-(OCH,CH,),OH where R® represents the fatty groups derived from lanolin and n=>5 to 75 or R°CO- (OCH,CH,), OH where R’CO- represents the fatty acids derived from lanolin and n=5 to 100. Specific examples include lanolin, lanolin oil, lanolin wax, lanolin alcohols, - lanolin fatty acids, isopropyl lanolate, ethoxylated lanolin and acetylated lanolin alcohols. (g) alkoxylated alcohols wherein the alcohol portion is selected from aliphatic alcohols having 2-18 and more particularly 4-18 carbons, and the alkylene portion is selected from the group consisting of ethylene oxide, and propylene oxide having a number of alkylene oxide units from 2-53 and, more particularly, from 2-15.
Specific examples include PPG-14 butyl ether and PPG-53 butyl ether. (h) silicones and silanes the linear organo-substituted polysiloxanes which are polymers of silicon/oxygen with general structure: (1) (R),S10(Si (R');0),Si(R"); where R', R" and R"? can be the same . or different and are each independently selected from the group consisting of phenyl and C1-C60 alkyl; } 35 (2) HOR™),SiO(Si (R),0),Si(R'),0H, where R", R" and R'® can be the same or different and are each independently selected from the group consisting of phenyl and C1-C60 alkyl; or
(3) organo substituted silicon compounds of formula RVSiR'*)OSiR" which are not polymeric where RY, R'® and R" can be the same or different and are each independently selected from the group consisting of phenyl and C1-
C60 alkyl optionally with one or both of the terminal R groups also containing 3) an hydroxyl group. Specific examples include dimethicone, dimethiconol behenate, Csoys alkyl methicone, stearoxytrimethylsilane, phenyl trimethicone and stearyl dimethicone. 1) mixtures and blends of two or more of the foregoing.
Emollients of special interest include C12-15 alkyl benzoate (FINSOLV TN from Finetex Inc., Elmwood Park, NJ), isopropyl myristate; and neopentyl glycol diheptanoate.
The emollient or emollient mixture or blend thereof incorporated in compositions according to the present invention can, illustratively, be included in amounts of 0.5 - 50 %, preferably 1 - 25 %, more preferably 3 - 12 %, by weight, of the total weight of the composition.
One particular elastomer of interest is KSG-15 silicone elastomer from Shin-
Etsu Silicones of America (Akron, Ohio).
The antiperspirant active can be selected from the group consisting of any of the known antiperspirant active materials. These include, by way of example (and not of a limiting nature), aluminum chlorohydrate, aluminum chloride, aluminum sesquichlorohydrate, zirconyl hydroxychloride, aluminum-zirconium glycine complex (for example, aluminum zirconium trichlorohydrex gly, aluminum zirconium pentachlorohydrex gly, aluminum zirconium tetrachlorohydrex gly and aluminum zirconium octochlorohydrex gly), aluminum chlorohydrex PG, aluminum chlorohydrex
PEG, aluminum dichlorohydrex PG, and aluminum dichlorohydrex PEG. The aluminum-containing materials can be commonly referred to as antiperspirant active aluminum salts. Generally, the foregoing metal antiperspirant active materials are antiperspirant active metal salts. In the embodiments which are antiperspirant compositions according to the present invention, such compositions need not include aluminum-containing metal salts, and can include other antiperspirant active materials, including other antiperspirant active metal salts. Generally, Category I active antiperspirant ingredients listed in the Food and Drug Administration's Monograph on . antiperspirant drugs for over-the-counter human use can be used. In addition, any new drug, not listed in the Monograph, such as aluminum nitratohydrate and its combination . 35 with zirconyl hydroxychlorides and nitrides, or aluminum-stannous chlorohydrates, can : be incorporated as an antiperspirant active ingredient in antiperspirant compositions according to the present invention. _7-
Particular types of antiperspirant actives include aluminum zirconium trichlorohydrex and aluminum zirconium tetrachlorohydrex either with or without glycine. A particular antiperspirant active is aluminum trichlorohydrex gly such as
AZ7-902 SUF (from Reheis Inc., Berkley Heights, NJ) which has 98% of the particles 8 less than 10 micrans in size.
Antiperspirant actives can be incorporated into compositions according to the present invention in amounts in the range of 0.1 — 25% of the final composition, but the amount used will depend on the formulation of the composition. For example, at amounts in the lower end of the broader range (for example, 0.1 - 10% on an actives basis), a deodorant effect may be observed. At lower levels the antiperspirant active material will not substantially reduce the flow of perspiration, but will reduce malodor, for example, by acting as an antimicrobial material. At amounts of 10-25% (on an actives basis) such as 15 - 25%, by weight, of the total weight of the composition, an antiperspirant effect may be observed.
The antiperspirant active material is desirably included as particulate matter suspended in the composition of the present invention in amounts as described above, but can also be added as solutions or added directly to the mixture.
The polyethylene beads useful with this invention have a density in the range of 0.91-0.98 g/cm’ and a particle size in the range of 5-40 microns, with one particular type of polyethylene having a particle size of 20 microns. All particle sizes are averages. Several types of suitable polyethylene beads that are commercially available are MICROTHENE FN 510 from Equistar Chemicals LP (Houston, Texas); ACUMIST
A-6 from Allied Signal Corp., Morristown, NJ), and Performalene™ (New Phase
Technology, Piscataway, NJ). It is believed that the polyethylene component contributes to the reduction in syneresis and is also responsible for giving the products a powdery feel as determined by trained sensory panels.
Suitable antimicrobial agents include, for example, bacteriostatic quaternary ammonium compounds such as 2-amino-2-methyl-1-propanol (AMP), cetyl- trimethylammonium bromide, cetyl pyridinium chloride, 2, 4, 4’-trichloro-2’- hydroxydiphenylether (Triclosan), N-(4-chlorophenyl)-N’-(3,4-dichlorophenyl)urea (Triclocarban), silver halides, octoxyglycerin (Sensiva™ SC 50) and various zinc salts (for example, zinc ricinoleate). The bacteriostat can, illustratively, be included in the . composition in an amount of 0-5%, particularly 0.01-1.0% by weight, of the total weight of the composition. Triclosan, can illustratively be included in an amount of } 35 from 0.05% to about 0.5% by weight, of the total weight of the composition. -
A variety of fragrances can be used in these compositions if a scented products is desired. Fragrances can be used in an amount in the range of 0-5%, particularly 0.01- -2.0%, and, for example, at a level of 1%. . Masking agents can be used in an amount of 0.05-5.0% (particularly 0.05-2%) by weight based on the total weight of the composition if an unscented product is , desired.
Other various optional components include those described in U.S. Patents
Numbers 5.019.375 to Tanner et al; 4,937,069 to Shin; and 5,102,656, each of which is incorporated by reference in its entirety herein. Examples of such additional ingredients include fragrances, coloring agents, opacificers, etc. in types and amounts conventionally used for such products.
These compositions are soft solids made as suspensions and thickened or gelled by the elastomer component. While other thickeners may be used, the compositions of this invention will normally use the elastomer component as the only gellant. Of course various viscosities for a soft solid may be made depending on the amount of elastomer material and the amount of other ingredients used. One group having a more viscous form will have a viscosity in the range of 25,000-2,000,000 centipoise, particularly 50,000 — 1,000,000 centipoise, and suitable for use with an applicator with porous openings or slots such as those described in USSN 9/191,897 (PCT 99/25570) incorporated by reference herein as to the description of the applicators. Another form will have a lower viscosity such as in the range of 20,000-200,000 centipoise and will be suitable for use with applicators requiring a thinner composition, for example roll-on applicators which have a rolling ball structure. For example, such roll-on applicators are described in U.S. Patents Numbers 5,158,385 and 4,984,921. incorporated by reference herein as to the description of the applicators. : While various forms have been described, it is believed that the compositions made according to this inventions should preferably have a ratio of elastomer to antiperspirant active in the range of 1:2-1:20 in order to achieve the optimum improved efficacy and the improved stability that has been observed.
Compositions according to the present invention can be made by mixing the silicone gel material with surfactant(s) , active ingredient(s) and optionally one or more of emollient(s), thickener(s) and fragrance. Mixing conditions and the use of heating will depend on what types of materials are being combined and; the melting points for those materials as are known to those skilled in the art. For example if soft solids, roll- : 35 ons or gels are being made, temperatures, in the range of room temperature or slightly higher (for example, 25-50 degrees C, particularly 23-30 degrees C) may be used. For stick products and soft solid/cream products made with higher melting point materials
(for example, high temperature waxes) temperatures from 25-85 degrees C may be used. The mixture can be introduced into dispensing containers known to those skilled in the art including those for solids, gels, roll-ons, soft solids and creams. In one particular example, slotted dispensers may be used such as those known in the art, for example, those having a parallel Tow or rows of straight or curved slots or holes with a screw mechanism for forcing the composition through the top as the product is used.
Where the dispensing containers have a top surface with slots therein, the composition can be rubbed onto the skin from the top surface of the container (itself fed from a reservoir of product in the container) so as to deposit an adequate amount of the cosmetic composition on to the skin. The cosmetic composition, for example, an antiperspirant and/or deodorant in the form of a soft solid, can be extruded from inside the dispensing container through the slots or holes onto the top of the surface of the dispensing container, and from there may be applied to the skin in the axillary regions to deposit sufficient amounts of antiperspirant and/or deodorant active material to reduce body malodor and/or reduce perspiration in axillary regions of the human body.
Various forms of the invention can be exemplified by the following formulations but should not be construed as limitations on the invention:
Soft Solid (a) 1-20% of a volatile silicone such as D4 or D5 cyclomethicone (or mixtures thereof); (b) an emollient component comprising 0.1-8% of FINSOLV TN C12-15 alkyl benzoate, 1-8% neopentyl glycol diheptanoate, 0.5-2% isopropyl myristate and 0.1-1.5% of a non-volatile silicone such as phenyltrimethicone; (©) 40-60% elastomer composition (KSG-15 elastomer composition); (d) 15-25% antiperspirant active; (e) 3-10% polyethylene beads of the type described above; and ® optionally 0.5-1.5% fragrance.
The following Examples are offered as illustrative of the invention and are not to be construed as limitations thereon. In the Examples and elsewhere in the description of the invention, chemical symbols and terminology have their usual and customary meanings. In the Examples as elsewhere in this application (2) values for n, ) m, etc. in formulas, molecular weights and degree of ethoxylation or propoxylation are averages; (b) temperatures are in degrees C unless otherwise indicated; and (c) the . 35 amounts of the components are in weight percents based on the standard described; if no other standard is described then the total weight of the composition is to be inferred.
Various names of chemical components include those listed in the CTFA International
Claims (10)
1. A low residue antiperspirant and/or deodorant compositions comprising: (a) 40-75% of a volatile silicone; , (b) 0.1-20% of an emollient which may be a single emollient or a mixture of emollients; (c) 0.5-6% (on a solids basis) of a dimethicone/vinyldimethicone crosspolymer composition made by reacting a polymethylhydrogensiloxane with an alpha, omega-divinylpolydimethyl siloxane; (d) 0.1-20% of an antiperspirant active based on an anhydrous, buffer-free basis; - (e) 2-15% of polyethylene beads having a particle size in the range of 5-40 microns and a density in the range of 0.91-0.98 g/cm’; (f) 0-5% antimicrobial agent; and 18 (g) 0-5% fragrance; : wherein all percents are in percents by weight based on the total weight of the composition unless otherwise indicated.
2. An antiperspirant and/or deodorant composition according to Claim 1 comprising 45-60 weight % of a volatile silicone.
3. An antiperspirant and/or deodorant composition according to Claim 1 or 2 wherein the volatile silicone is cyclomethicone.
4. An antiperspirant and/or deodorant composition according to Claim 1 comprising - 2-18 weight % of an emollient wherein the emollient comprises one or more members selected from the group consisting of:
(a) fats and oils which are the glyceryl esters of fatty acids or triglycerides of Formula III: CH,-COOR! : I ° CH-COOR? 1, COOR’ Formula III wherein each of R, R%, and R? may be the same or different and have a carbon chain length (saturated or unsaturated) of 7 to 30; (b) hydrocarbons; (c) esters of formula R‘CO-OR’ , wherein the chain length for each of R* and R’ is from 7 to 30 and can be saturated or unsaturated, straight chained or branched; (d) saturated and unsaturated fatty acids having a formula R°*COOH wherein R® has a carbon chain between 7-30 and can be straight or branched chain; (e) saturated and unsaturated fatty alcohols having a formula R'COH wherein R’ has a carbon chain between 7-30 and can be straight or branched chain; @® lanolin and its derivatives; i (g) alkoxyated alcohols wherein the alcohol portion is selected from aliphatic alcohols having 2-18 and more particularly 4-18 carbons, and the alkylene portion is selected from the group consisting of ethylene oxide, and propylene oxide having a number of alkylene oxide units from 2-53; (h) silicones and silanes which are members of the group consisting of polymers of silicon/oxygen having general structures: (1) (R™®),Si0(Si (R),0),Si(R'?), where R'’, R" and R" can be the same * or different and are each independently selected from the group consisting of : phenyl and C1-C60 alkyl;
@ HO(R™),Si0(Si (R%),0).Si(R'%),0H, where R™, R" and R'® can be the same or different and are each independently selected from the group consisting of phenyl and C1-C60 alkyl; or ] (3) organo substituted silicon compounds of formula R7Si(R®*)OSiR" ; 5 which are not polymeric where R', R™ and RY can be the same or different and are each independently selected from the group consisting of phenyl and C1- C60 alkyl optionally with one or both of the terminal R groups also containing an hydroxyl group; and (i) mixtures and blends of two or more of (a)-(h).
5. An antiperspirant and/or deodorant composition according to Claim 4 wherein the emollient is one or more members selected from the group consisting of dimethicone, dimethiconol behenate, C,,,s alkyl methicone, stearoxytrimethylsilane, phenyl trimethicone and stearyl dimethicone.
6. An antiperspirant and/or deodorant composition according to Claim 1 comprising 1-6 weight % of the dimethicone/vinyldimethicone crosspolymer composition.
7. An antiperspirant and/or deodorant composition according to Claim 1 comprising 2-5 weight % of the dimethicone/vinyldimethicone crosspolymer composition.
8. An antiperspirant and/or deodorant composition according to Claim 1 e 25 comprising 10-20 weight % of an antiperspirant active.
9. An antiperspirant and/or deodorant composition according to Claim 1 comprising 2-10 weight % of polyethylene beads. ' 5
10. An antiperspirant/deodorant composition according to Claim 1 which is made as a soft solid and which comprises: (a) 1-20 weight % of cyclomethicone; (b) 1-20 weight % of an emollient component comprising 1-8% of C12-15 alkyl benzoate; 0.5-5% neopentyl glycol diheptanoate; 0.5-2% isopropyl myristate; 0.4-
1.5% of phenyltrimethicone; (c) 40-60 weight % of a 4-10% dimethicone/vinyldimethicone crosspolymer composition in cyclomethicone; (d) 15-25 weight % antiperspirant active; (e) 2-10 weight % polyethylene beads; and (f) optionally 0.5-1.5 weight % fragrance. a 1 4
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US19437300P | 2000-04-04 | 2000-04-04 |
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ZA200207807B true ZA200207807B (en) | 2003-09-29 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ZA200207807A ZA200207807B (en) | 2000-04-04 | 2002-09-27 | Stable and efficacious soft solid product. |
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GT (1) | GT200100053A (en) |
ZA (1) | ZA200207807B (en) |
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2001
- 2001-04-03 GT GT200100053A patent/GT200100053A/en unknown
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