ZA200201647B - Methods of and compositions for inhibiting the proliferation of mammalian cells. - Google Patents
Methods of and compositions for inhibiting the proliferation of mammalian cells. Download PDFInfo
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- ZA200201647B ZA200201647B ZA200201647A ZA200201647A ZA200201647B ZA 200201647 B ZA200201647 B ZA 200201647B ZA 200201647 A ZA200201647 A ZA 200201647A ZA 200201647 A ZA200201647 A ZA 200201647A ZA 200201647 B ZA200201647 B ZA 200201647B
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- 230000026683 transduction Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
- 229940029284 trichlorofluoromethane Drugs 0.000 description 1
- 229960002324 trifluoperazine Drugs 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 230000005748 tumor development Effects 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 229910000384 uranyl sulfate Inorganic materials 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- XOSXWYQMOYSSKB-LDKJGXKFSA-L water blue Chemical compound CC1=CC(/C(\C(C=C2)=CC=C2NC(C=C2)=CC=C2S([O-])(=O)=O)=C(\C=C2)/C=C/C\2=N\C(C=C2)=CC=C2S([O-])(=O)=O)=CC(S(O)(=O)=O)=C1N.[Na+].[Na+] XOSXWYQMOYSSKB-LDKJGXKFSA-L 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/27—Endoribonucleases producing 3'-phosphomonoesters (3.1.27)
- C12Y301/27001—Ribonuclease T2 (3.1.27.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38541199A | 1999-08-30 | 1999-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200201647B true ZA200201647B (en) | 2003-05-28 |
Family
ID=23521271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200201647A ZA200201647B (en) | 1999-08-30 | 2002-02-27 | Methods of and compositions for inhibiting the proliferation of mammalian cells. |
Country Status (15)
| Country | Link |
|---|---|
| EP (3) | EP2165605B1 (zh) |
| JP (2) | JP4808346B2 (zh) |
| AT (1) | ATE421856T1 (zh) |
| AU (1) | AU769011B2 (zh) |
| CA (1) | CA2382303C (zh) |
| CU (1) | CU23065A3 (zh) |
| DE (1) | DE60041495D1 (zh) |
| EA (1) | EA004929B1 (zh) |
| ES (3) | ES2396998T3 (zh) |
| HK (2) | HK1045081B (zh) |
| IL (1) | IL148345A0 (zh) |
| MX (1) | MXPA02002162A (zh) |
| NZ (1) | NZ517579A (zh) |
| WO (1) | WO2001015531A1 (zh) |
| ZA (1) | ZA200201647B (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2165605B1 (en) * | 1999-08-30 | 2012-10-10 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Use of a ribonuclease of the T2 family having actin-binding activity for inhibiting and/or reversing proliferation |
| US7811981B2 (en) | 1999-08-30 | 2010-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods of and compositions for inhibiting the proliferation of mammalian cells |
| BRPI0516302A (pt) * | 2004-09-29 | 2008-09-02 | Yissun Res Dev Company Of The | rnase t2 humana recombinante e suas utilizações |
| CZ302164B6 (cs) * | 2008-06-20 | 2010-11-24 | Biologické centrum AV CR, v. v. i. | Rekombinantní rostlinná nukleáza jako protinádorové terapeutikum s nízkými nežádoucími úcinky |
| US20160340659A1 (en) | 2014-01-30 | 2016-11-24 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. | Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786457A (en) * | 1989-02-23 | 1998-07-28 | Colorado State University Research Foundation | Hormone-nuclease compounds and method for regulating hormone related diseases |
| EP2165605B1 (en) * | 1999-08-30 | 2012-10-10 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Use of a ribonuclease of the T2 family having actin-binding activity for inhibiting and/or reversing proliferation |
| BRPI0516302A (pt) * | 2004-09-29 | 2008-09-02 | Yissun Res Dev Company Of The | rnase t2 humana recombinante e suas utilizações |
-
2000
- 2000-08-29 EP EP08168000A patent/EP2165605B1/en not_active Expired - Lifetime
- 2000-08-29 CU CU20020044A patent/CU23065A3/es unknown
- 2000-08-29 EA EA200200312A patent/EA004929B1/ru not_active IP Right Cessation
- 2000-08-29 ES ES08168000T patent/ES2396998T3/es not_active Expired - Lifetime
- 2000-08-29 ES ES00954879T patent/ES2319096T3/es not_active Expired - Lifetime
- 2000-08-29 IL IL14834500A patent/IL148345A0/xx unknown
- 2000-08-29 EP EP00954879A patent/EP1207755B1/en not_active Expired - Lifetime
- 2000-08-29 ES ES10183935T patent/ES2397052T3/es not_active Expired - Lifetime
- 2000-08-29 AT AT00954879T patent/ATE421856T1/de not_active IP Right Cessation
- 2000-08-29 EP EP10183935A patent/EP2294918B8/en not_active Expired - Lifetime
- 2000-08-29 WO PCT/IL2000/000514 patent/WO2001015531A1/en active Application Filing
- 2000-08-29 DE DE60041495T patent/DE60041495D1/de not_active Expired - Lifetime
- 2000-08-29 MX MXPA02002162A patent/MXPA02002162A/es active IP Right Grant
- 2000-08-29 AU AU67228/00A patent/AU769011B2/en not_active Ceased
- 2000-08-29 JP JP2001519760A patent/JP4808346B2/ja not_active Expired - Fee Related
- 2000-08-29 NZ NZ517579A patent/NZ517579A/en not_active IP Right Cessation
- 2000-08-29 CA CA2382303A patent/CA2382303C/en not_active Expired - Fee Related
-
2002
- 2002-02-27 ZA ZA200201647A patent/ZA200201647B/en unknown
- 2002-09-05 HK HK02106527.7A patent/HK1045081B/zh not_active IP Right Cessation
-
2011
- 2011-07-06 JP JP2011149849A patent/JP5467076B2/ja not_active Expired - Fee Related
- 2011-07-22 HK HK11107656.7A patent/HK1157137A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1207755A4 (en) | 2004-11-10 |
| HK1045081A1 (en) | 2002-11-15 |
| IL148345A0 (en) | 2002-09-12 |
| DE60041495D1 (de) | 2009-03-19 |
| EP2165605A1 (en) | 2010-03-24 |
| EP2165605B1 (en) | 2012-10-10 |
| EP2294918A1 (en) | 2011-03-16 |
| JP5467076B2 (ja) | 2014-04-09 |
| WO2001015531A1 (en) | 2001-03-08 |
| MXPA02002162A (es) | 2002-11-04 |
| EA004929B1 (ru) | 2004-10-28 |
| ATE421856T1 (de) | 2009-02-15 |
| HK1157137A1 (en) | 2012-06-29 |
| EP1207755A1 (en) | 2002-05-29 |
| EP2294918B8 (en) | 2012-11-14 |
| CU23065A3 (es) | 2005-07-19 |
| EA200200312A1 (ru) | 2002-10-31 |
| ES2396998T3 (es) | 2013-03-01 |
| JP2003508411A (ja) | 2003-03-04 |
| AU6722800A (en) | 2001-03-26 |
| AU769011B2 (en) | 2004-01-15 |
| ES2397052T3 (es) | 2013-03-04 |
| CA2382303A1 (en) | 2001-03-08 |
| EP2294918B1 (en) | 2012-10-10 |
| HK1045081B (zh) | 2009-08-07 |
| ES2319096T3 (es) | 2009-05-04 |
| NZ517579A (en) | 2004-02-27 |
| EP1207755B1 (en) | 2009-01-28 |
| JP4808346B2 (ja) | 2011-11-02 |
| JP2011251971A (ja) | 2011-12-15 |
| CA2382303C (en) | 2013-02-12 |
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