ZA200006837B - Efficient ex vivo expansion of CD4+ and CD8+ T-cells from HIV infected subjects. - Google Patents

Efficient ex vivo expansion of CD4+ and CD8+ T-cells from HIV infected subjects. Download PDF

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Publication number
ZA200006837B
ZA200006837B ZA200006837A ZA200006837A ZA200006837B ZA 200006837 B ZA200006837 B ZA 200006837B ZA 200006837 A ZA200006837 A ZA 200006837A ZA 200006837 A ZA200006837 A ZA 200006837A ZA 200006837 B ZA200006837 B ZA 200006837B
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ZA
South Africa
Prior art keywords
cells
hiv
cell
population
subject
Prior art date
Application number
ZA200006837A
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English (en)
Inventor
David Bell
Kenneth Rosenthal
Original Assignee
Hemosol Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemosol Inc filed Critical Hemosol Inc
Publication of ZA200006837B publication Critical patent/ZA200006837B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/11Coculture with; Conditioned medium produced by blood or immune system cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA200006837A 1998-04-24 2000-11-22 Efficient ex vivo expansion of CD4+ and CD8+ T-cells from HIV infected subjects. ZA200006837B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8286198P 1998-04-24 1998-04-24

Publications (1)

Publication Number Publication Date
ZA200006837B true ZA200006837B (en) 2001-05-22

Family

ID=22173909

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200006837A ZA200006837B (en) 1998-04-24 2000-11-22 Efficient ex vivo expansion of CD4+ and CD8+ T-cells from HIV infected subjects.

Country Status (7)

Country Link
US (1) US6610542B1 (de)
EP (1) EP1073720A2 (de)
AU (1) AU769538B2 (de)
CA (1) CA2326378A1 (de)
NZ (1) NZ508242A (de)
WO (1) WO1999055843A2 (de)
ZA (1) ZA200006837B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8412377B2 (en) 2000-01-24 2013-04-02 Irobot Corporation Obstacle following sensor scheme for a mobile robot
WO2004003142A2 (en) * 2002-06-28 2004-01-08 Xcyte Therapies, Inc. Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20050084967A1 (en) 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20040175373A1 (en) * 2002-06-28 2004-09-09 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
JP4111394B2 (ja) * 2003-12-22 2008-07-02 北海道ティー・エル・オー株式会社 改変標的化t細胞の製造方法及び医薬
KR101600225B1 (ko) 2005-06-08 2016-03-04 다나-파버 캔서 인스티튜트 인크. 예정 세포사 1(pd-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
CA2658227A1 (en) 2006-01-17 2007-07-26 Health Research, Inc. Heteroduplex tracking assay
JP5623747B2 (ja) * 2006-12-27 2014-11-12 エモリー ユニバーシティ 感染症および腫瘍を処置するための組成物および方法
CA2744449C (en) * 2008-11-28 2019-01-29 Emory University Methods for the treatment of infections and tumors
WO2014134547A1 (en) * 2013-02-28 2014-09-04 Therabiol, Inc. Hiv antigens and antibodies
WO2016081859A2 (en) * 2014-11-20 2016-05-26 The Johns Hopkins University Method and compositions for the prevention and treatment of a hiv infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6167394A (en) * 1993-01-27 1994-08-15 Hemosol Inc. Selective cell proliferation
WO1997005239A1 (en) * 1995-07-25 1997-02-13 Celltherapy, Inc. Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
CA2263978A1 (en) 1996-08-27 1998-03-05 Hemosol Inc. Enhanced stimulation of erythropoiesis
WO1998033891A1 (en) * 1997-01-31 1998-08-06 Hemosol Inc. Method for the production of selected lymphocytes

Also Published As

Publication number Publication date
WO1999055843A3 (en) 2000-01-13
WO1999055843A2 (en) 1999-11-04
AU769538B2 (en) 2004-01-29
NZ508242A (en) 2003-05-30
CA2326378A1 (en) 1999-11-04
AU3591199A (en) 1999-11-16
US6610542B1 (en) 2003-08-26
EP1073720A2 (de) 2001-02-07

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