ZA200004743B - Method for detecting antibodies or antigens and for determining blood groups. - Google Patents
Method for detecting antibodies or antigens and for determining blood groups.Info
- Publication number
- ZA200004743B ZA200004743B ZA200004743A ZA200004743A ZA200004743B ZA 200004743 B ZA200004743 B ZA 200004743B ZA 200004743 A ZA200004743 A ZA 200004743A ZA 200004743 A ZA200004743 A ZA 200004743A ZA 200004743 B ZA200004743 B ZA 200004743B
- Authority
- ZA
- South Africa
- Prior art keywords
- antigens
- test fluid
- antibodies
- vessel
- binding partner
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
Abstract
The invention relates to a method for detecting antibodies or antigens in a test fluid as well as for determining blood groups by reaction with a defined specific binding partner. The antigen or antibody or specific binding partner are either present in free form in the test fluid or bonded to a support. In case of a positive antigen-antibody reaction an agglutinate of antigens or antibodies, the corresponding binding partners and the support materials is formed, which can be optically detected. A microreaction vessel having a cross-section which narrows from the top downwards contains a viscous substance, notably a gel. A test fluid is placed into the vessel. The specific binding partner is added to either the test fluid or the gel, or a liquid containing said binding partner is added to the vessel after the test fluid has been placed in it. The sedimentation image is then evaluated optically. A flat agglutinate of antigens or antibodies, binding partners and support materials indicates a positive antigen-antibody reaction, a deposit of antigens or antibodies and binding partners and/or support materials in the lower, narrow area of the vessel indicates a negative reaction. The above method can be carried out in a fully automated manner, for example by using a pipetting robot.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19856703A DE19856703C2 (en) | 1998-12-09 | 1998-12-09 | Methods for the detection of antibodies or antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200004743B true ZA200004743B (en) | 2001-04-11 |
Family
ID=7890449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200004743A ZA200004743B (en) | 1998-12-09 | 2000-09-08 | Method for detecting antibodies or antigens and for determining blood groups. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1064557B1 (en) |
AT (1) | ATE266205T1 (en) |
AU (1) | AU2660500A (en) |
DE (2) | DE19856703C2 (en) |
WO (1) | WO2000034790A2 (en) |
ZA (1) | ZA200004743B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10358565B4 (en) * | 2003-12-15 | 2007-06-28 | P.A.L.M. Microlaser Technologies Ag | A receiving element for receiving an object released from a biological mass by means of laser radiation and method for obtaining and processing a biological object |
DE102004006470B4 (en) * | 2004-02-06 | 2006-06-01 | Senova Gesellschaft für Biowissenschaft und Technik mbH | Absorption photometric method for quantitative substance analysis |
DE102006024927B4 (en) * | 2006-05-25 | 2008-12-11 | DRK-Blutspendedienst Baden-Württemberg-Hessen gemeinnützige GmbH | Method for the detection of antibodies and / or antigens and for blood group determination in a test substance |
DE102008018155A1 (en) | 2008-04-08 | 2009-10-15 | Olympus Life Science Research Europa Gmbh | Agglutination test to detect antibodies in plasma or serum sample, comprises incubating a test mixture comprising sample liquid, erythrocyte containing test reagent, repulsion reducing reagents and antibody crosslinking substances |
ITMI20081273A1 (en) * | 2008-07-11 | 2010-01-12 | A De Mori S P A | PROCEDURE OF ERITROCITARY IMMUNOEMATOLOGY |
CN108693361B (en) * | 2017-09-25 | 2021-03-09 | 广东睿碁生物科技有限公司 | Zirconia micro-bead ABO blood type positive and negative sizing reagent card and preparation method thereof |
CN108693360B (en) * | 2017-09-25 | 2021-03-09 | 广东睿碁生物科技有限公司 | Zirconia micro-bead rare blood type detection reagent card and preparation method thereof |
CN108693346B (en) * | 2017-09-25 | 2021-03-09 | 广东睿碁生物科技有限公司 | Lectin A1 blood group detection reagent card and preparation method thereof |
CN108693359B (en) * | 2017-09-25 | 2021-02-09 | 广东睿碁生物科技有限公司 | Zirconia microbead Rh blood type typing reagent card and preparation method thereof |
CN113640528A (en) * | 2021-06-28 | 2021-11-12 | 青岛益柏生物科技有限公司 | Detection method of full-automatic RH system blood type detector |
JP2023150022A (en) | 2022-03-31 | 2023-10-16 | 日本光電工業株式会社 | Blood test apparatus, blood test method, and blood test program |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2577321B1 (en) * | 1985-02-08 | 1989-04-28 | Lapierre Yves | DEVICE AND METHOD FOR EVIDENCE OF ERYTHROCYTA AGGLUTINATES |
US5338689A (en) * | 1987-08-24 | 1994-08-16 | Stiftung Fur Diagnostische Forschung | Method and card for detecting antigens and/or antibodies |
JPH087215B2 (en) * | 1987-08-24 | 1996-01-29 | シュティフツング・フュア・ディアグノスティッシュ・フォルシュンク | Method for detecting antigen and / or antibody and test kit for detection |
GR1002306B (en) * | 1990-11-09 | 1996-05-08 | Ortho Diagnostic Systems Inc. | Method for joining columns and disposition therefor |
JPH04113060U (en) * | 1991-03-20 | 1992-10-01 | オリンパス光学工業株式会社 | Reaction vessel for liquid optical measurement |
JP3157601B2 (en) * | 1992-04-27 | 2001-04-16 | オリンパス光学工業株式会社 | Automatic blood analyzer |
-
1998
- 1998-12-09 DE DE19856703A patent/DE19856703C2/en not_active Expired - Fee Related
-
1999
- 1999-12-09 AU AU26605/00A patent/AU2660500A/en not_active Abandoned
- 1999-12-09 DE DE59909404T patent/DE59909404D1/en not_active Expired - Lifetime
- 1999-12-09 AT AT99968790T patent/ATE266205T1/en not_active IP Right Cessation
- 1999-12-09 WO PCT/EP1999/009721 patent/WO2000034790A2/en active IP Right Grant
- 1999-12-09 EP EP99968790A patent/EP1064557B1/en not_active Expired - Lifetime
-
2000
- 2000-09-08 ZA ZA200004743A patent/ZA200004743B/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2000034790A3 (en) | 2000-11-09 |
DE19856703C2 (en) | 2001-02-01 |
DE19856703A1 (en) | 2000-07-06 |
EP1064557A2 (en) | 2001-01-03 |
AU2660500A (en) | 2000-06-26 |
EP1064557B1 (en) | 2004-05-06 |
ATE266205T1 (en) | 2004-05-15 |
WO2000034790A2 (en) | 2000-06-15 |
DE59909404D1 (en) | 2004-06-09 |
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