YU87292A - COMPOSITION FOR INPUTING NUCLEIC ACID COMPLEXES IN MORE EUKARIOTIC CELLS - Google Patents
COMPOSITION FOR INPUTING NUCLEIC ACID COMPLEXES IN MORE EUKARIOTIC CELLSInfo
- Publication number
- YU87292A YU87292A YU87292A YU87292A YU87292A YU 87292 A YU87292 A YU 87292A YU 87292 A YU87292 A YU 87292A YU 87292 A YU87292 A YU 87292A YU 87292 A YU87292 A YU 87292A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- nucleic acid
- composition
- cells
- acid complexes
- inputing
- Prior art date
Links
Abstract
KOMPOZICIJA ZA UNOŠENJE KOMPLEKSA NUKLEINSKE KISELINE U VIŠE EUKARIOTIČNE ĆELIJE obuhvata komplekse nukleinske kiseline, supstancu koja una afinitet za nukleinsku kiselinu i opciono intemalizujući faktor, sadrži endosomolitično sredstvo, na pr. virus ili komponentu virusa koja može biti konjugovana. Endosomolitično sredstvo, koje je opiciono deo kompleksa nukleinske kiseline, se internalizuje u ćelije zajedno sa kompleksom i oslobađa sadržaje endozoma u citoplazmu, pri tome povećava gen transfer kapacitet. Farmaceutski preparati, transfekcioni skupovi i postupci za unošenje nukleinske kiseline u više eukariotične ćelije tretiranjem ćelija sa kompozicijom su takođe opisani.A COMPOSITION FOR INJECTING NUCLEIC ACID COMPLEXES TO MORE EUKARIOTIC CELLS comprises nucleic acid complexes, a substance that has an affinity for nucleic acids and optionally an intemalizing factor, containing an endosomolytic agent, e.g. a virus or a component of a virus that can be conjugated. The endosomolytic agent, which is optionally part of the nucleic acid complex, internalizes into cells together with the complex and releases endosome contents into the cytoplasm, thereby increasing gene transfer capacity. Pharmaceutical preparations, transfection sets, and methods for introducing nucleic acid into multiple eukaryotic cells by treating the cells with the composition are also described.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76803991A | 1991-09-30 | 1991-09-30 | |
US76778891A | 1991-09-30 | 1991-09-30 | |
US82710392A | 1992-01-30 | 1992-01-30 | |
US82710292A | 1992-01-30 | 1992-01-30 | |
US86475992A | 1992-04-07 | 1992-04-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU87292A true YU87292A (en) | 1996-08-13 |
Family
ID=47556981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU87292A YU87292A (en) | 1991-09-30 | 1992-09-28 | COMPOSITION FOR INPUTING NUCLEIC ACID COMPLEXES IN MORE EUKARIOTIC CELLS |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW250497B (en) |
YU (1) | YU87292A (en) |
-
1992
- 1992-09-21 TW TW081107454A patent/TW250497B/zh active
- 1992-09-28 YU YU87292A patent/YU87292A/en unknown
Also Published As
Publication number | Publication date |
---|---|
TW250497B (en) | 1995-07-01 |
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