YU40716B - Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine - Google Patents

Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine

Info

Publication number
YU40716B
YU40716B YU1725/78A YU172578A YU40716B YU 40716 B YU40716 B YU 40716B YU 1725/78 A YU1725/78 A YU 1725/78A YU 172578 A YU172578 A YU 172578A YU 40716 B YU40716 B YU 40716B
Authority
YU
Yugoslavia
Prior art keywords
methyl
thioethylù
guanidine
cyano
obtaining
Prior art date
Application number
YU1725/78A
Other versions
YU172578A (en
Inventor
Z Crnic
G Karlovic
G Radobolja
S Djokic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Priority to YU1725/78A priority Critical patent/YU40716B/en
Priority to DE2928857A priority patent/DE2928857C3/en
Priority to CH669479A priority patent/CH643246A5/en
Priority to GB7925042A priority patent/GB2025969B/en
Priority to SU792790358A priority patent/SU886744A3/en
Priority to AT0498379A priority patent/AT366033B/en
Priority to IT68506/79A priority patent/IT1121013B/en
Publication of YU172578A publication Critical patent/YU172578A/en
Publication of YU40716B publication Critical patent/YU40716B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU1725/78A 1978-07-19 1978-07-19 Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine YU40716B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
YU1725/78A YU40716B (en) 1978-07-19 1978-07-19 Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine
DE2928857A DE2928857C3 (en) 1978-07-19 1979-07-17 Process for the preparation of N-cyano-N'-methyl-N''-[2-{[(5-methylimidazol-4-yl)-methyl]-thio}-ethyl]-guanidine
CH669479A CH643246A5 (en) 1978-07-19 1979-07-18 METHOD FOR PRODUCING N-cyano-N'-methyl-N '' - (2 - (((5-methylimidazol-4-yl) methyl) thio) ethyl) guanidine.
GB7925042A GB2025969B (en) 1978-07-19 1979-07-18 Process for preparing n - cyano - n'- methyl - n''- (2-(((5 - methylimidazol - 4 - yl) - methylthio) - ethyl) - guanidine
SU792790358A SU886744A3 (en) 1978-07-19 1979-07-19 Method of preparing n-cyano-n'-methyl-n"-(2-/(5-methyl-imidazol-4-yl)-methylthio/-ethyl)-guanidine
AT0498379A AT366033B (en) 1978-07-19 1979-07-19 METHOD FOR PRODUCING N-CYANO-N'-METHYL-N "- (2 - ((5-METHYLIMIDAZOL-4-YL-METHYL) -THIOAETHYL) -GUANIDINE
IT68506/79A IT1121013B (en) 1978-07-19 1979-07-19 PROCEDURE FOR THE PREPARATION OF CIMETIDINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU1725/78A YU40716B (en) 1978-07-19 1978-07-19 Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine

Publications (2)

Publication Number Publication Date
YU172578A YU172578A (en) 1982-10-31
YU40716B true YU40716B (en) 1986-04-30

Family

ID=25555343

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1725/78A YU40716B (en) 1978-07-19 1978-07-19 Process for obtaining n-cyano-n'-methyl-n'-û2-|5-metylimidazole4-yl)-methyl¨-thioethylù guanidine

Country Status (7)

Country Link
AT (1) AT366033B (en)
CH (1) CH643246A5 (en)
DE (1) DE2928857C3 (en)
GB (1) GB2025969B (en)
IT (1) IT1121013B (en)
SU (1) SU886744A3 (en)
YU (1) YU40716B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU185298B (en) * 1981-06-26 1984-12-28 Richter Gedeon Vegyeszet Process for producing cimetidine
HU185636B (en) * 1981-06-26 1985-03-28 Richter Gedeon Vegyeszet Process for preparing new cimetidine-hydrate /cimetidine-h/
MY100734A (en) * 1986-09-01 1991-01-31 Mitsui Petrochemical Ind Process for preparation of guanidine derivative.
JPH0629234B2 (en) * 1986-12-26 1994-04-20 三井石油化学工業株式会社 α-acyloxyketone derivative
US5808090A (en) * 1996-02-22 1998-09-15 Endo Pharmaceuticals Inc. Process for preventing precipitation in cimetidine injection solutions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397436A (en) 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1533380A (en) 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531221A (en) 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives

Also Published As

Publication number Publication date
GB2025969B (en) 1982-09-02
YU172578A (en) 1982-10-31
IT7968506A0 (en) 1979-07-19
ATA498379A (en) 1981-07-15
CH643246A5 (en) 1984-05-30
DE2928857A1 (en) 1980-02-07
IT1121013B (en) 1986-03-26
DE2928857B2 (en) 1981-07-23
SU886744A3 (en) 1981-11-30
DE2928857C3 (en) 1988-02-11
GB2025969A (en) 1980-01-30
AT366033B (en) 1982-03-10

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