YU394A - NEW Peptides That Act As Opiate Receptor Antagonists And Procedures For Making Them - Google Patents
NEW Peptides That Act As Opiate Receptor Antagonists And Procedures For Making ThemInfo
- Publication number
- YU394A YU394A YU394A YU394A YU394A YU 394 A YU394 A YU 394A YU 394 A YU394 A YU 394A YU 394 A YU394 A YU 394A YU 394 A YU394 A YU 394A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- phe
- tic
- tyr
- procedures
- act
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
NOVI PEPTIDI KOJI DELUJU KAO ANTAGONISTI OPIJATSKIH RECEPTORA I POSTUPCI ZA NJIHOVU IZRADU - Pronalazak se odnosi na peptide formule I kao i na postupke za njihovo pripremanje, njihove farmaceutski preparati i njihovu primenu, sa izuzetkom jedinjenja: Tyr-Tic-Phe-OH, Tyr-Tic-Phe-NH2, Tyr-Tic-Phe-Phe-OH, Tyr-Tic-Phe-Phe-NH2, Tyr-Tic-Trp-Phe-NH2, Tyr-Tic-Trp- Phe-OH, Tyr-Tic-Phe-Phe(p-N02)-OH, Tyr-Tic-Phe-Phe(p-N02)-H,Tyr-Tic-Phe-Trp-NH2> i Tyr-Tic-Phe-Phe-Leu-Nle-Asp-NH2.The invention relates to peptides of formula I as well as to processes for their preparation, their pharmaceutical preparations and their use, with the exception of the compounds: Tyr-Tic-Phe-OH Tic-Phe-NH2, Tyr-Tic-Phe-Phe-OH, Tyr-Tic-Phe-Phe-NH2, Tyr-Tic-Trp-Phe-NH2, Tyr-Tic-Trp-Phe-OH, Tyr-Tic- Phe-Phe (p-NO2) -OH, Tyr-Tic-Phe-Phe (p-NO2) -H, Tyr-Tic-Phe-Trp-NH2> and Tyr-Tic-Phe-Phe-Leu-Nle-Asp -NH2.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9300012A SE9300012D0 (en) | 1993-01-05 | 1993-01-05 | NEW PEPTIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU394A true YU394A (en) | 1997-07-31 |
Family
ID=20388466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU394A YU394A (en) | 1993-01-05 | 1994-01-05 | NEW Peptides That Act As Opiate Receptor Antagonists And Procedures For Making Them |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5602099A (en) |
| EP (1) | EP0678099A1 (en) |
| JP (1) | JPH08505386A (en) |
| KR (1) | KR960700269A (en) |
| CN (1) | CN1096515A (en) |
| AP (1) | AP508A (en) |
| AU (1) | AU681372B2 (en) |
| CA (1) | CA2152380A1 (en) |
| CZ (1) | CZ171195A3 (en) |
| EE (1) | EE9400326A (en) |
| FI (1) | FI953302A (en) |
| HU (1) | HUT72597A (en) |
| IL (1) | IL108169A0 (en) |
| IS (1) | IS4115A (en) |
| LV (1) | LV10962B (en) |
| MX (1) | MX9400255A (en) |
| NO (1) | NO952650L (en) |
| NZ (1) | NZ259597A (en) |
| PL (1) | PL309778A1 (en) |
| SE (1) | SE9300012D0 (en) |
| SI (1) | SI9400005A (en) |
| SK (1) | SK83995A3 (en) |
| WO (1) | WO1994015959A1 (en) |
| YU (1) | YU394A (en) |
| ZA (1) | ZA9455B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2167881C2 (en) * | 1993-12-23 | 2001-05-27 | Ново Нордиск А/С | Compounds promoting growth hormone release |
| IS4261A (en) * | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | New peptide opioids for the treatment of pain and their use |
| IL114046A0 (en) * | 1994-06-20 | 1995-10-31 | Astra Ab | New opioid peptide antagonists |
| RU2067000C1 (en) * | 1994-06-29 | 1996-09-27 | Владислав Исакович Дейгин | Peptide and a method of its synthesis |
| US6184208B1 (en) | 1994-06-29 | 2001-02-06 | Immunotech Developments Inc. | Peptide, a method for its preparation and a pharmaceutical composition containing the peptide |
| SE9402880D0 (en) * | 1994-08-30 | 1994-08-30 | Astra Ab | New peptide derivatives |
| US5780589A (en) * | 1994-11-30 | 1998-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Ultraselective opioidmimetic peptides and pharmacological and therapeutic uses thereof |
| EP0837857A4 (en) * | 1995-03-29 | 1998-08-05 | Merck & Co Inc | Inhibitors of farnesyl-protein transferase |
| EP0837875A4 (en) * | 1995-03-29 | 1998-10-07 | Merck & Co Inc | Inhibitors of farnesyl-protein transferase |
| DE19512484A1 (en) | 1995-04-04 | 1996-10-17 | Bayer Ag | Carbohydrate modified cytostatics |
| SE9600769D0 (en) * | 1996-02-28 | 1996-02-28 | Astra Ab | Compounds useful as analgesic |
| US6903075B1 (en) | 1997-05-29 | 2005-06-07 | Merck & Co., Inc. | Heterocyclic amide compounds as cell adhesion inhibitors |
| JP2002512625A (en) * | 1997-05-29 | 2002-04-23 | メルク エンド カンパニー インコーポレーテッド | Heterocyclic amide compounds as cell adhesion inhibitors |
| US6703381B1 (en) | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
| US6306576B1 (en) * | 1999-02-19 | 2001-10-23 | Cleveland Clinic Foundation | Diagnostic methods for asthma |
| US7601739B2 (en) | 2003-08-08 | 2009-10-13 | Virgina Commonwealth University | Compounds having antiestrogenic and tissue selective estrogenic properties, and compounds with anti-androgenic properties for treatment of prostate cancer and androgen receptor dependent diseases |
| US20110104186A1 (en) | 2004-06-24 | 2011-05-05 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| JP2008514612A (en) * | 2004-09-23 | 2008-05-08 | ミシャロウ、アレクサンダー | Methods of modulating neurotransmitter systems by inducing counter adaptation |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| WO2015200828A1 (en) * | 2014-06-27 | 2015-12-30 | H. Lee Moffit Cancer Center And Research Institute, Inc. | Conjugates for immunotherapy |
-
1993
- 1993-01-05 SE SE9300012A patent/SE9300012D0/en unknown
- 1993-12-20 AU AU58448/94A patent/AU681372B2/en not_active Ceased
- 1993-12-20 PL PL93309778A patent/PL309778A1/en unknown
- 1993-12-20 CZ CZ951711A patent/CZ171195A3/en unknown
- 1993-12-20 SK SK839-95A patent/SK83995A3/en unknown
- 1993-12-20 CA CA002152380A patent/CA2152380A1/en not_active Abandoned
- 1993-12-20 HU HU9502041A patent/HUT72597A/en unknown
- 1993-12-20 WO PCT/SE1993/001090 patent/WO1994015959A1/en not_active Application Discontinuation
- 1993-12-20 EP EP94904365A patent/EP0678099A1/en not_active Withdrawn
- 1993-12-20 JP JP6515914A patent/JPH08505386A/en active Pending
- 1993-12-20 NZ NZ259597A patent/NZ259597A/en unknown
- 1993-12-20 KR KR1019950702750A patent/KR960700269A/en not_active Application Discontinuation
- 1993-12-24 IL IL10816993A patent/IL108169A0/en unknown
- 1993-12-27 IS IS4115A patent/IS4115A/en unknown
-
1994
- 1994-01-04 MX MX9400255A patent/MX9400255A/en unknown
- 1994-01-04 US US08/176,938 patent/US5602099A/en not_active Expired - Fee Related
- 1994-01-05 AP APAP/P/1994/000605A patent/AP508A/en active
- 1994-01-05 YU YU394A patent/YU394A/en unknown
- 1994-01-05 SI SI9400005A patent/SI9400005A/en unknown
- 1994-01-05 ZA ZA9455A patent/ZA9455B/en unknown
- 1994-01-05 CN CN94100129A patent/CN1096515A/en active Pending
- 1994-11-03 EE EE9400326A patent/EE9400326A/en unknown
-
1995
- 1995-06-29 LV LVP-95-197A patent/LV10962B/en unknown
- 1995-07-04 NO NO952650A patent/NO952650L/en not_active Application Discontinuation
- 1995-07-04 FI FI953302A patent/FI953302A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9400255A (en) | 1994-07-29 |
| JPH08505386A (en) | 1996-06-11 |
| AP508A (en) | 1996-07-22 |
| IL108169A0 (en) | 1994-04-12 |
| ZA9455B (en) | 1994-07-05 |
| HUT72597A (en) | 1996-05-28 |
| AU681372B2 (en) | 1997-08-28 |
| KR960700269A (en) | 1996-01-19 |
| CZ171195A3 (en) | 1996-09-11 |
| SI9400005A (en) | 1994-12-31 |
| EE9400326A (en) | 1996-04-15 |
| WO1994015959A1 (en) | 1994-07-21 |
| AU5844894A (en) | 1994-08-15 |
| LV10962A (en) | 1995-12-20 |
| LV10962B (en) | 1997-04-20 |
| IS4115A (en) | 1994-07-06 |
| AP9400605A0 (en) | 1994-01-31 |
| FI953302A0 (en) | 1995-07-04 |
| NO952650L (en) | 1995-08-30 |
| FI953302A (en) | 1995-07-04 |
| CA2152380A1 (en) | 1994-07-21 |
| SK83995A3 (en) | 1996-09-04 |
| HU9502041D0 (en) | 1995-09-28 |
| US5602099A (en) | 1997-02-11 |
| CN1096515A (en) | 1994-12-21 |
| NZ259597A (en) | 1996-07-26 |
| EP0678099A1 (en) | 1995-10-25 |
| SE9300012D0 (en) | 1993-01-05 |
| NO952650D0 (en) | 1995-07-04 |
| PL309778A1 (en) | 1995-11-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| YU394A (en) | NEW Peptides That Act As Opiate Receptor Antagonists And Procedures For Making Them | |
| ATE169031T1 (en) | CELL RECEPTOR SPECIFIC MONOCLONAL ANTIBODIES AGAINST STEM CELL FACTOR RECEPTOR | |
| EA200300441A1 (en) | ASSOCIATION OF THE ANTAGONIST OF THE RECEPTOR CB1 AND SIBUTRAMINE CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR APPLICATION FOR THE TREATMENT OF OBESITY | |
| MXPA02006028A (en) | Daptomycin analogs and their use as antibacterial agents. | |
| YU5396A (en) | New biologically active proteins, their pharmaceutical formulas and production process | |
| YU54592A (en) | CHEMICAL UNITS | |
| MXPA02006029A (en) | Novel lipopeptides as antibacterial agents. | |
| BG66085B1 (en) | Phenylalanine derivatives | |
| IL232501A0 (en) | Stable analogs of peptide and polypeptide therapeutics | |
| MXPA02006030A (en) | Lipopeptides as antibacterial agents. | |
| UA66750C2 (en) | Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors | |
| IL160171A0 (en) | Depsipeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same | |
| EA200201138A1 (en) | PEPTIDE, MODELING RECEPTOR THROMBOPOETHINE | |
| YU4197A (en) | Isolable compositions starting from eugenia iambolana lamarc, their preparation and application of this compositions and some of ingredients thereof as medicaments | |
| DK1079849T3 (en) | Use of HMG proteins for the preparation of drugs with cytotoxic effect | |
| YU15895A (en) | 5-VINYL AND 5-ETHINYL-HINOLONE CARBONIC ACIDS PROCEDURES FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF MEDICINES | |
| GR3032950T3 (en) | Substituted fused and bridged bicyclic compounds as therapeutic agents | |
| MX9706927A (en) | Bicyclic tachykinins antagonists, preparation thereof and their use in pharmaceutical composition. | |
| ATE384078T1 (en) | PARALYTIC PEPTIDES FROM THE SHREW AND ITS USE IN THE THERAPY OF NEUROMUSCULAR DISEASES | |
| YU48997A (en) | Novel biologically active proteins, their pharmaceutical compositions and procedure for obtaining thereof | |
| BR0000850B1 (en) | mixture of 6-substituted 3-methyloct-6-enols, adoring composition containing said mixture as well as its use. | |
| MY118946A (en) | Novel intermediates and their use to prepare n, n''- bridged bisindolylmaleimides | |
| MEP59108A (en) | Memno peptides, a process for their preparation and their use | |
| MXPA02012015A (en) | Ligands of integrin receptors. | |
| AP9901529A0 (en) | Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them. |