YU190286A - PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST - Google Patents

PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST

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Publication number
YU190286A
YU190286A YU190286A YU190286A YU190286A YU 190286 A YU190286 A YU 190286A YU 190286 A YU190286 A YU 190286A YU 190286 A YU190286 A YU 190286A YU 190286 A YU190286 A YU 190286A
Authority
YU
Yugoslavia
Prior art keywords
atp
cell
intracellular
carbon dioxide
level
Prior art date
Application number
YU190286A
Other languages
Serbo-Croatian (sh)
Inventor
D.T. Rogers
J.W. Szostak
Original Assignee
Genetics Institute Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute Inc. filed Critical Genetics Institute Inc.
Priority to YU190286A priority Critical patent/YU190286A/en
Publication of YU190286A publication Critical patent/YU190286A/en

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Abstract

POSTUPAK ZA POVEĆAVANJE NIVOA PROIZVODNJE UGLJEN DIOKSIDA I ETANOLA U KVASCU. Sadašnji pronalazak daje postupak za povećavanje nivoa proizvodnje ugljen dioksida, etanola i drugih fermentacionih proizvoda kao što je limunska kiselina, koje proizvode kvasci kao što je Saccaromyces cerevisiae za vreme fermentacije, i smanjenje proizvodnje biomase, regulisanjem brzine glikolize indirektno, izmenom energetskog balansa ćelije, tj. redukcijom intracelularnih nivoa ATP. Modifikacije komija se na ovaj način menja brzina glikolize uključuju korišćenje bilo regulisane hidrolize ATP unutar ćelije, bilo regulisanog "curenja" ATP iz ćelije. Sadašnji pronalazak obuhvata menjanje ćelijskog nivoa ATP uključujući (a) korišćenje "praznih" metaboličkih ciklusa radi trošenja ATP; (B) korišćenje izmenjene egzocelularne kisele fosfataze tako da ona postaje intracelularna i povećava hidrolizu intracelularnog ATP; (c) korišćenjem sredstva koje dekupluje ATPazu plazmatične membrane, čime se troši nenormalno visok nivo ATP; i (d) korišćenje sredstva koje omogućava oslobodjenje ATP iz ćelije, čime se snižava intracelularni nivo ATP.PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST. The present invention provides a process for increasing production levels of carbon dioxide, ethanol and other fermentation products such as citric acid, produced by yeasts such as Saccaromyces cerevisiae during fermentation, and reducing biomass production, by regulating glycolysis rate indirectly, altering cell energy balance. . by reducing intracellular ATP levels. Modifications of the coma in this way to alter the rate of glycolysis involve the use of either regulated hydrolysis of ATP within the cell or regulated "leakage" of ATP from the cell. The present invention encompasses altering cellular ATP levels including (a) using "empty" metabolic cycles to deplete ATP; (B) using altered exocellular acid phosphatase so that it becomes intracellular and increases the hydrolysis of intracellular ATP; (c) using a plasma membrane ATPase decoupling agent, thereby consuming abnormally high ATP levels; and (d) using an agent that allows the release of ATP from the cell, thereby lowering the intracellular level of ATP.

YU190286A 1986-11-10 1986-11-10 PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST YU190286A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
YU190286A YU190286A (en) 1986-11-10 1986-11-10 PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU190286A YU190286A (en) 1986-11-10 1986-11-10 PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST

Publications (1)

Publication Number Publication Date
YU190286A true YU190286A (en) 1992-12-21

Family

ID=47278013

Family Applications (1)

Application Number Title Priority Date Filing Date
YU190286A YU190286A (en) 1986-11-10 1986-11-10 PROCEDURE FOR INCREASING THE LEVEL OF CARBON DIOXIDE AND ETHANOL PRODUCTION IN YEAST

Country Status (1)

Country Link
YU (1) YU190286A (en)

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