YU163681A - Process for obtaining compounds of mucolytic activity which are not absorbed in tissues - Google Patents

Process for obtaining compounds of mucolytic activity which are not absorbed in tissues

Info

Publication number
YU163681A
YU163681A YU01636/81A YU163681A YU163681A YU 163681 A YU163681 A YU 163681A YU 01636/81 A YU01636/81 A YU 01636/81A YU 163681 A YU163681 A YU 163681A YU 163681 A YU163681 A YU 163681A
Authority
YU
Yugoslavia
Prior art keywords
tissues
absorbed
mucolytic activity
obtaining compounds
mucolytic
Prior art date
Application number
YU01636/81A
Other languages
English (en)
Inventor
J E Maltz
Original Assignee
Texcontor Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texcontor Ets filed Critical Texcontor Ets
Publication of YU163681A publication Critical patent/YU163681A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
    • C12Y301/21001—Deoxyribonuclease I (3.1.21.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
YU01636/81A 1980-07-01 1981-07-01 Process for obtaining compounds of mucolytic activity which are not absorbed in tissues YU163681A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8023161A IT1209419B (it) 1980-07-01 1980-07-01 Composti ad attivita' mucolitica non assimilabili, processo per laloro preparazione e composizioni terapeutiche che li comprendono come principio attivo.

Publications (1)

Publication Number Publication Date
YU163681A true YU163681A (en) 1983-09-30

Family

ID=11204417

Family Applications (1)

Application Number Title Priority Date Filing Date
YU01636/81A YU163681A (en) 1980-07-01 1981-07-01 Process for obtaining compounds of mucolytic activity which are not absorbed in tissues

Country Status (11)

Country Link
US (2) US4409138A (fr)
EP (1) EP0045285B1 (fr)
JP (1) JPS5813522A (fr)
AT (1) ATE7202T1 (fr)
AU (1) AU7241281A (fr)
CA (1) CA1168169A (fr)
DE (1) DE3163287D1 (fr)
ES (1) ES503527A0 (fr)
FR (1) FR2485925A1 (fr)
IT (1) IT1209419B (fr)
YU (1) YU163681A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574360B2 (en) * 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
US4585754A (en) * 1984-01-09 1986-04-29 Valcor Scientific, Ltd. Stabilization of proteins and peptides by chemical binding with chondroitin
CA1317860C (fr) * 1987-04-01 1993-05-18 Daniel Louis Kacian Techniques pour la preparation de specimens pour des epreuves bacteriennes
US5128132A (en) * 1988-11-22 1992-07-07 Parnell Pharmaceuticals, Inc. Eriodictyon compositions and methods for treating internal mucous membranes
BR0210493A (pt) * 2001-07-03 2004-06-22 Alcon Inc Composição, e, método para remover cerume humano
US20060182705A1 (en) * 2005-02-11 2006-08-17 Cruse Maria K Composition for reduction and prevention of wrinkles on the skin
EP3797783A1 (fr) * 2019-09-27 2021-03-31 Freie Universität Berlin Nouvelles utilisations médicales de dérivés de polyglycérol fonctionnalisés de thiol

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR924877A (fr) * 1946-03-15 1947-08-19 Procédé de fabrication de préparations vétérinaires
US4004979A (en) * 1968-03-29 1977-01-25 Agence Nationale De Valorisation De La Recherche (Anvar) Preparation of active proteins cross-linked to inactive proteins
NL6812443A (fr) * 1968-08-31 1970-03-03
BE758425A (fr) * 1969-12-02 1971-04-16 Baxter Laboratories Inc Streptokinase liee chimiquement a une matrice en carbohydrate (
US3683069A (en) * 1970-02-19 1972-08-08 Michel Hooreman Enzymatic products which optimize the viscosity of mucuses and their applications
JPS5443074B1 (fr) * 1971-04-14 1979-12-18
BE790326A (fr) * 1971-10-20 1973-04-19 Pechiney Ugine Kuhlmann Nouveau derive d'hydroxyquinoleine
US4185090A (en) * 1972-02-02 1980-01-22 Abbott Laboratories Chemically modified endotoxin immunizing agent
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
SE431758B (sv) * 1977-03-04 1984-02-27 Pharmacia Fine Chemicals Ab Som tioleringsreagens eller berarmatris for enzymer anvendbart derivat av en sh-grupphaltig polymer
CS204190B1 (en) * 1978-02-22 1981-03-31 Jaroslav Drobnik Activation method for hydrxyl groups containing insoluble carriers
US4259233A (en) * 1979-10-23 1981-03-31 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates

Also Published As

Publication number Publication date
ATE7202T1 (de) 1984-05-15
EP0045285A1 (fr) 1982-02-03
DE3163287D1 (en) 1984-05-30
US4409138A (en) 1983-10-11
ES8203420A1 (es) 1982-04-01
ES503527A0 (es) 1982-04-01
US4559322A (en) 1985-12-17
AU7241281A (en) 1982-01-07
FR2485925B1 (fr) 1985-05-24
EP0045285B1 (fr) 1984-04-25
CA1168169A (fr) 1984-05-29
IT1209419B (it) 1989-07-16
IT8023161A0 (it) 1980-07-01
FR2485925A1 (fr) 1982-01-08
JPS5813522A (ja) 1983-01-26

Similar Documents

Publication Publication Date Title
NL191308B (nl) Gelyofiliseerd, na oplossing injecteerbaar preparaat dat een antracycline-glycoside bevat, alsmede werkwijze voor de bereiding van een injecteerbare oplossing van een antracycline-glycoside.
YU163681A (en) Process for obtaining compounds of mucolytic activity which are not absorbed in tissues
EP0191357A3 (fr) Traitement de l'ophtalmie avec du biphénamine
IT8321884A0 (it) Procedimento per isomerizzare glucosio.
JPS53136528A (en) Cosmetics
ES309630A1 (es) Procedimiento de preparacion de un material anticoagulante.
ES395861A1 (es) Procedimiento para la preparacion de esteres de nucleosido-difosfato.
ES426414A1 (es) Metodo para producir una preparacion de ciclocitidina seca-da por congelacion.
CA1262912C (fr) Derives de substitution tetrahydrofuranyliques d'analogues de la prostaglandine
YU37476A (en) Rocess for obtaining an immobilized enzymatic conjugate
JPS5437889A (en) Preparation of polysaccharide
ES486851A1 (es) Un procedimiento de preparacion de acido 3a,7b-dihidroxico- lanico
ES508646A0 (es) Procedimiento de fermentacion para producir cuzinas, acidos organicos, antibioticos, polisacaridos, acidos aminatos y vitaminas.
JPS5257392A (en) Immobilized enzyme using fibroin as carrier and method of preparing th e same
JPS5264494A (en) Preparation of fr-1923 substance
DE2961506D1 (en) N-cyclohexyl-n-methoxy-acetoacetamide, process for its preparation and its use to prepare o-methyl-n-cyclohexyl-2,5-dimethyl-furane-3-hydroxamic acid
JPS53130486A (en) Preparation of immobilized enzyme
ATE69551T1 (de) Zusammensetzung zur behandlung von boesartigen tumoren insbesondere bei tieren.
SU606244A1 (ru) Способ получени комбинированного антибиотического перепарата
GR3003950T3 (fr)
JPS5290687A (en) Highly active glucoseisomerase concentrate having high storage stabili ty
ES375480A1 (es) Un procedimiento en la produccion de composiciones depila- doras.
ES522000A0 (es) Un procedimiento para tratar un material de glucosa antes de su conversion enzimatica en fructosa.
JPS5257391A (en) Immobilized enzyme using keratin as carrier and method of preparing th e same
JPS5324709A (en) Connecting system for spare receivers currently in use