YU156276A - Process for obtaining halo-substituted derivatives of 1-lower alkyl-5-aroylprrolo-2-acetic acid - Google Patents

Process for obtaining halo-substituted derivatives of 1-lower alkyl-5-aroylprrolo-2-acetic acid

Info

Publication number
YU156276A
YU156276A YU01562/76A YU156276A YU156276A YU 156276 A YU156276 A YU 156276A YU 01562/76 A YU01562/76 A YU 01562/76A YU 156276 A YU156276 A YU 156276A YU 156276 A YU156276 A YU 156276A
Authority
YU
Yugoslavia
Prior art keywords
aroylprrolo
halo
obtaining
acetic acid
lower alkyl
Prior art date
Application number
YU01562/76A
Other languages
English (en)
Inventor
J Carson
Original Assignee
Mc Ner Lab Incorp Camo Hill Ro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mc Ner Lab Incorp Camo Hill Ro filed Critical Mc Ner Lab Incorp Camo Hill Ro
Publication of YU156276A publication Critical patent/YU156276A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU01562/76A 1975-06-27 1976-06-25 Process for obtaining halo-substituted derivatives of 1-lower alkyl-5-aroylprrolo-2-acetic acid YU156276A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/591,217 US4048191A (en) 1975-06-27 1975-06-27 Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds

Publications (1)

Publication Number Publication Date
YU156276A true YU156276A (en) 1983-01-21

Family

ID=24365579

Family Applications (1)

Application Number Title Priority Date Filing Date
YU01562/76A YU156276A (en) 1975-06-27 1976-06-25 Process for obtaining halo-substituted derivatives of 1-lower alkyl-5-aroylprrolo-2-acetic acid

Country Status (23)

Country Link
US (1) US4048191A (nl)
JP (1) JPS525761A (nl)
AT (1) AT361462B (nl)
AU (1) AU508884B2 (nl)
BE (1) BE843454A (nl)
CA (1) CA1094084A (nl)
CH (1) CH624936A5 (nl)
CS (1) CS222227B2 (nl)
DE (1) DE2628475A1 (nl)
DK (1) DK274676A (nl)
ES (1) ES449083A1 (nl)
FR (1) FR2316942A1 (nl)
GB (1) GB1540437A (nl)
IL (1) IL49911A (nl)
IN (1) IN144407B (nl)
IT (1) IT1062038B (nl)
NL (1) NL7606999A (nl)
PH (1) PH11645A (nl)
PT (1) PT65280B (nl)
RO (1) RO70264B (nl)
SE (1) SE418083B (nl)
YU (1) YU156276A (nl)
ZA (1) ZA763814B (nl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200645A (en) * 1977-05-10 1980-04-29 Beecham Group Limited Pyrrole derivatives
US4119639A (en) * 1977-06-27 1978-10-10 Mcneil Laboratories, Incorporated Preparation of 5-aroylpyrrole-2-acetic acid derivatives
GB1592996A (en) * 1977-10-10 1981-07-15 Rolland Sa A Acylated pyrrole carboxylic acids and derivatives thereof
US4246175A (en) * 1979-05-29 1981-01-20 Ethyl Corporation Synthesis of 5-cyano-1-hydrocarbylpyrrole-2-acetic acid
US4213905A (en) * 1979-06-25 1980-07-22 Mcneilab, Inc. Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts
US4246176A (en) * 1979-07-05 1981-01-20 Ethyl Corporation Synthesis of 5-aroyl-1-hydrocarbylpyrrole-2-acetic acid
DE3065460D1 (en) * 1979-07-28 1983-12-08 Beecham Group Plc Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them
US4363918A (en) * 1979-09-11 1982-12-14 Janssen Pharmaceutica N.V. Method of preparing 1-alkyl-3-carboxy-1H pyrrole-2-acetic acids
US4565878A (en) * 1980-04-04 1986-01-21 Ethyl Corporation Process for producing substituted pyrroles
US4333878A (en) * 1980-04-04 1982-06-08 Ethyl Corporation Process for producing substituted pyrroles
US4565879A (en) * 1980-04-04 1986-01-21 Ethyl Corporation Process for producing substituted pyrroles
US4374255A (en) * 1980-04-04 1983-02-15 Ethyl Corporation Process for producing substituted pyrroles
US4388468A (en) * 1980-04-04 1983-06-14 Ethyl Corporation Process for producing substituted pyrroles
US4299770A (en) * 1980-05-29 1981-11-10 Mallinckrodt, Inc. Recovery of substituted pyrrole acetate
US4396626A (en) * 1980-10-09 1983-08-02 Beecham Group Limited Cyclic compounds and their use
US4511576A (en) * 1981-04-23 1985-04-16 Pfizer Inc. Antidiabetic pyrrolecarboxylic acids
US4374997A (en) * 1981-06-04 1983-02-22 Merck & Co., Inc. Process for the preparation of zomepirac and related compounds
US4434175A (en) 1981-08-10 1984-02-28 Merck & Co., Inc. Nonsteroidal compounds as anti-inflammatory and analgesic agents
ES8206468A1 (es) * 1981-11-16 1982-08-16 Pharmedical Sa Lab Procedimiento de preparacion de derivados del acido 2-pirrol-acetico.
IT1153750B (it) * 1982-09-21 1987-01-14 Montedison Spa Processo per la preparazione dell'acido 3-carbossi-1-metilpirrol-2-acetico
US4533671A (en) * 1982-10-08 1985-08-06 Merck & Co., Inc. 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2-alkanoic or carboxylic acids and analogs as anti-inflammatory and analgesic agents
US4536512A (en) * 1982-10-08 1985-08-20 Merck & Co., Inc. 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2,3-dihydro-1H-pyrrolizine-1-alkanoic or carboxylic acids and use thereof as anti-inflammatory and analgesic agents
US4937368A (en) * 1987-01-14 1990-06-26 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4835288A (en) * 1987-01-14 1989-05-30 Syntex Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates
CA1334975C (en) * 1987-11-13 1995-03-28 James H. Holms Furan and pyrrole containing lipoxygenase inhibiting compounds
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655693A (en) * 1969-06-25 1972-04-11 Merck & Co Inc Anti-inflammatory salicyclic acid derivatives
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
US3952012A (en) * 1970-01-26 1976-04-20 Mcneil Laboratories, Incorporated Aroyl-substituted pyrroles
US3707478A (en) * 1970-06-15 1972-12-26 Mcneilab Inc 5-aroyl-2-(beta-r3-ethyl)-1-loweralkyl-pyrroles
US3721680A (en) * 1970-06-15 1973-03-20 Mc Neil Labor Inc 5-aroyl-2-(beta-hydroxyethyl)-1-loweralkylpyrroles
BE792042A (fr) * 1971-11-30 1973-05-29 Ciba Geigy Procede de preparation de nouvelles alcenylene-amines substituees en 3
US3803169A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc Cycloalkanoyl-substituted pyrroles
US3803171A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc 5-phenylacetyl-pyrroles
US3846447A (en) * 1972-08-03 1974-11-05 Mcneilab Inc Preparation of 5-aroyl-pyrroles and intermediates therefor
US3998844A (en) * 1975-06-02 1976-12-27 Mcneil Laboratories, Incorporated Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Also Published As

Publication number Publication date
AT361462B (de) 1981-03-10
ATA468276A (de) 1980-08-15
IL49911A0 (en) 1976-08-31
IL49911A (en) 1979-09-30
CA1094084A (en) 1981-01-20
BE843454A (fr) 1976-12-27
DE2628475A1 (de) 1977-01-13
PT65280A (en) 1976-07-01
PT65280B (en) 1978-05-08
FR2316942B1 (nl) 1978-12-22
SE7607240L (sv) 1976-12-28
JPS525761A (en) 1977-01-17
GB1540437A (en) 1979-02-14
DK274676A (da) 1976-12-28
ZA763814B (en) 1978-02-22
AU1515976A (en) 1978-01-05
PH11645A (en) 1978-05-08
SE418083B (sv) 1981-05-04
NL7606999A (nl) 1976-12-29
RO70264B (ro) 1983-04-30
IN144407B (nl) 1978-04-29
IT1062038B (it) 1983-06-25
ES449083A1 (es) 1977-11-16
RO70264A (ro) 1983-04-29
FR2316942A1 (fr) 1977-02-04
US4048191A (en) 1977-09-13
CS222227B2 (en) 1983-05-27
AU508884B2 (en) 1980-04-03
CH624936A5 (nl) 1981-08-31

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