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Priority claimed from US07/322,398external-prioritypatent/US4963538A/en
Application filed by Merck & Co. Inc.filedCriticalMerck & Co. Inc.
Publication of YU127289ApublicationCriticalpatent/YU127289A/en
Novi inhibitori HMB-CoA reduktaze, su korisni kao antihiperholesterolemski agensi i predstavljeni su sledećim formulama (I) ili (II) pri čemu položaj 5 polihidronaftil prstena je jednostruko ili dvostruko vezan za kiseonik ili inkorporiran u C3-7 karbocikličan prsten.The novel HMB-CoA reductase inhibitors are useful as antihypercholesterolemic agents and are represented by the following formulas (I) or (II) wherein position 5 of the polyhydronaphthyl ring is single or double attached to oxygen or incorporated into a C3-7 carbocyclic ring.