YU12600A - Process for enhancing the optical purty of 2r-/1- hydroksy-1-trifluoromethyl-3-cyclopropylpropyn- 2yl/-4-chloraniline - Google Patents

Process for enhancing the optical purty of 2r-/1- hydroksy-1-trifluoromethyl-3-cyclopropylpropyn- 2yl/-4-chloraniline

Info

Publication number
YU12600A
YU12600A YU12600A YU12600A YU12600A YU 12600 A YU12600 A YU 12600A YU 12600 A YU12600 A YU 12600A YU 12600 A YU12600 A YU 12600A YU 12600 A YU12600 A YU 12600A
Authority
YU
Yugoslavia
Prior art keywords
cyclopropylpropyn
trifluoromethyl
enhancing
hydroksy
purty
Prior art date
Application number
YU12600A
Other languages
Serbo-Croatian (sh)
Inventor
Cheng Yi Chen
Paul J. Reider
Edward Grabowski
Lushi Tan
Richard Tillyer
Original Assignee
Merck & Co.Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co.Inc. filed Critical Merck & Co.Inc.
Publication of YU12600A publication Critical patent/YU12600A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for enhancing the purity of 2R-[1-hydroxy- 1-trifluoromethyl- 3-cyclopropylpropyn-2-yl] -4-chloroaniline comprising the formation of an acid addition salt which is capable of rejecting the racemate in the selected organic solvent.
YU12600A 1997-09-03 1998-09-01 Process for enhancing the optical purty of 2r-/1- hydroksy-1-trifluoromethyl-3-cyclopropylpropyn- 2yl/-4-chloraniline YU12600A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5789197P 1997-09-03 1997-09-03
GBGB9721985.1A GB9721985D0 (en) 1997-10-17 1997-10-17 Process for enhancing the optical purity
US9652998P 1998-08-13 1998-08-13

Publications (1)

Publication Number Publication Date
YU12600A true YU12600A (en) 2002-03-18

Family

ID=10820697

Family Applications (1)

Application Number Title Priority Date Filing Date
YU12600A YU12600A (en) 1997-09-03 1998-09-01 Process for enhancing the optical purty of 2r-/1- hydroksy-1-trifluoromethyl-3-cyclopropylpropyn- 2yl/-4-chloraniline

Country Status (3)

Country Link
GB (1) GB9721985D0 (en)
UA (1) UA56258C2 (en)
YU (1) YU12600A (en)

Also Published As

Publication number Publication date
UA56258C2 (en) 2003-05-15
GB9721985D0 (en) 1997-12-17

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