WO2024103207A1 - Canule pour pompage d'assistance ventriculaire, et dispositif d'assistance ventriculaire - Google Patents

Canule pour pompage d'assistance ventriculaire, et dispositif d'assistance ventriculaire Download PDF

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Publication number
WO2024103207A1
WO2024103207A1 PCT/CN2022/131669 CN2022131669W WO2024103207A1 WO 2024103207 A1 WO2024103207 A1 WO 2024103207A1 CN 2022131669 W CN2022131669 W CN 2022131669W WO 2024103207 A1 WO2024103207 A1 WO 2024103207A1
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WO
WIPO (PCT)
Prior art keywords
blood
cannula
head
hose
tail
Prior art date
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PCT/CN2022/131669
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English (en)
Chinese (zh)
Inventor
唐瑜珅
商光春
Original Assignee
生命盾医疗技术(苏州)有限公司
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Application filed by 生命盾医疗技术(苏州)有限公司 filed Critical 生命盾医疗技术(苏州)有限公司
Priority to PCT/CN2022/131669 priority Critical patent/WO2024103207A1/fr
Publication of WO2024103207A1 publication Critical patent/WO2024103207A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/17—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/17—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps
    • A61M60/174—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices

Definitions

  • the present invention relates to the field of medical instruments, and in particular to a cannula for ventricular assist blood pumping and a ventricular assist device.
  • Heart failure refers to a syndrome characterized by circulatory dysfunction caused by insufficient cardiac output to maintain tissue metabolism due to myocardial diastolic and/or systolic dysfunction under the condition of adequate venous return.
  • surgical intervention is a common treatment option, but this treatment option is high-risk, traumatic to patients and has high medical costs.
  • interventional artificial heart technology has broken this dilemma.
  • Interventional artificial heart technology is also known as "pVAD technology”.
  • pVAD technology is to insert a small blood pump into the ventricle percutaneously in an interventional manner.
  • the blood pump drains blood into the arterial system to partially or completely replace the heart's pumping function and maintain the body's blood circulation.
  • pVAD products, or interventional ventricular assist devices have high reliability requirements and are one of the most stringent and difficult medical devices to register for product safety and effectiveness.
  • the current pVAD products are safe and easy to operate, and are not prone to complications such as embolism and bleeding that adversely affect downstream organs. It is an advanced minimally invasive ventricular assist technology that can be used for indications such as cardiogenic shock, high-risk PCI surgery protection, and heart failure, helping to improve the survival rate of relevant patients.
  • the cannula head When the pVAD product is used, the cannula head is inserted into the left ventricle, and the cannula head must not be heavily pressed against the inner wall of the ventricle.
  • the existing cannula has a flexible protrusion coiled in a pigtail shape at the cannula head, that is, at the front end of the cannula liquid inlet.
  • the flexible protrusion can be supported on the inner wall of the ventricle during the process of pumping blood in the left ventricle to separate the cannula head from the inner wall of the ventricle.
  • the doctor's hand feeling, experience, or three-dimensional mapping system is completely relied on to roughly judge the contact of the cannula head with the endocardium, which has poor reliability and easily increases the risk of surgery.
  • the flexible protrusion is immersed in the flowing blood for a long time during the blood pumping process, it is very easy to form a coagulated blood clot (thrombus) at the flexible protrusion, further increasing the risk of surgery.
  • the purpose of the present invention is to provide a cannula and a ventricular assist device for ventricular assist blood pumping to solve the problem that the force between the head of the existing cannula and the inner wall of the ventricle is roughly judged entirely by the doctor's feel, experience, or three-dimensional mapping system, which has poor reliability and easily increases the risk of surgery.
  • the present invention provides the following solutions:
  • the present invention provides a cannula for ventricular auxiliary pumping, comprising:
  • a cannula body wherein the head of the cannula body is provided with a blood inlet, and the tail of the cannula body is provided with a bleeding outlet, the head of the cannula body is used to be inserted into the left ventricle of the heart, the tail of the cannula body is used to be connected to the aorta outside the heart, and the cannula body is used to be connected to a blood pumping power source to introduce the blood in the left ventricle of the heart into the aorta outside the heart;
  • a pressure detection device is arranged at the head of the cannula body and is located on the side of the blood inlet away from the tail of the cannula body.
  • the pressure detection device is used to detect the pressure on the head of the cannula body.
  • the cannula body comprises:
  • a head tubular joint wherein the first end of the head tubular joint is connected to the head of the blood-collecting hose, the second end of the head tubular joint is provided with a guide head, and the blood inlet is provided on the side wall between the first end and the second end of the head tubular joint; the pressure detection device is provided on the guide head;
  • a tail tubular joint wherein the first end of the tail tubular joint is connected to the tail of the blood-collecting hose, the second end of the tail tubular joint is used to connect to the blood pumping power source, and the tail tubular joint has the bleeding port on the side wall between the first end and the second end thereof.
  • the blood drainage hose comprises an elastic hose and a hose skeleton, wherein the hose skeleton is embedded in the tube wall of the elastic hose; wherein the hose skeleton comprises a plurality of metal rings spaced apart along the axial direction of the elastic hose, or the hose skeleton is formed by spirally winding metal sheets.
  • the elastic hose is made of soft biocompatible materials such as TPU or TPE.
  • the metal ring is a stainless steel ring, a nickel-titanium alloy ring or a platinum-iridium alloy ring.
  • the tail tubular joint and the blood-collecting hose are connected by curing with hot-flow glue.
  • the blood-collecting hose is bent at a distance of 1/3 of its length from the head, so that the head and the tail of the blood-collecting hose are arranged at an angle of 35° to 55°.
  • the guide head is a circular blunt head
  • a guide cone is arranged in the head tubular joint
  • the guide cone is connected to the circular blunt head
  • the tip of the guide cone is arranged toward the blood drainage hose.
  • the pressure detection device includes a developing ring and a pressure sensor, the developing ring is sleeved on the guide head, and the pressure sensor is arranged on the guide head.
  • the present invention further provides a ventricular assist device, comprising a blood pumping power source and the ventricular assist blood pumping cannula as described above, wherein the blood pumping power source is arranged at the second end of the tail tubular connector.
  • the blood pumping power source includes:
  • An impeller the impeller is arranged in the tail tubular joint, the impeller comprises an impeller shaft coaxially arranged with the tail tubular joint and a plurality of blades arranged on the outer periphery of the impeller shaft;
  • the output end of the motor is connected to the impeller shaft, and the second end of the tail tubular joint and the impeller shaft are both sealed and butted with the housing of the motor.
  • the impeller shaft is a conical impeller shaft, and the large end of the conical impeller shaft is arranged toward the motor, and the small end of the conical impeller shaft is arranged toward the blood drainage hose.
  • one end of any one of the blades close to the small end of the conical impeller shaft is spirally deflected, and the blades on the periphery of the impeller shaft are evenly distributed along the circumference of the impeller shaft.
  • the cannula for ventricular auxiliary pumping proposed by the present invention has a novel and reasonable structure. Its tail is used to connect with the aorta outside the heart and connect to the blood pumping power source, and the head is used to be inserted into the left ventricle; when the patient's heart pumping capacity is insufficient, the blood pumping power source is started, and the left ventricle blood can be pumped in through the blood inlet, and then flow through the cannula body and the bleeding port in sequence into the aorta outside the heart, and then flow to the whole body.
  • the head of the cannula body shall not press heavily on the inner wall of the left ventricle when pumping blood, and the position of the cannula body in the heart and the contact of the cannula head with the inner wall of the heart can be judged by the pressure detection device.
  • the present invention removes the pigtail-shaped flexible protrusion of the original cannula head, and adopts the pressure detection device to replace the manual experience, which can quantify the pressure induced by the cannula, and accurately display the lateral partial pressure and axial partial pressure of the cannula head in real time, so as to avoid the blood inlet and the inner wall of the heart from being attached during the blood pumping process, which is conducive to improving the auxiliary blood pumping effect; at the same time, the present invention removes the pigtail-shaped flexible protrusion on the cannula head, which can avoid the formation of thrombus during the auxiliary blood pumping process.
  • the ventricular assist device proposed in the present invention comprises a blood pumping power source and the above-mentioned ventricular assist blood pumping cannula, which determines the position of the cannula body in the heart and the contact of the cannula head with the endocardium through a pressure detection device.
  • the device removes the original pigtail-shaped flexible protrusion on the cannula head, and uses a pressure detection device to replace manual experience.
  • the present invention removes the pigtail-shaped flexible protrusion on the cannula head, which can avoid the formation of thrombus during the auxiliary blood pumping process.
  • FIG1 is a schematic diagram of the structure of a cannula for assisting ventricular pumping disclosed in an embodiment of the present invention
  • FIG2 is an enlarged view of the structure at A in FIG1 ;
  • FIG3 is an enlarged view of the structure at B in FIG1 ;
  • FIG4 is a schematic diagram of the structure of a ventricular assist device disclosed in an embodiment of the present invention.
  • FIG5 is a schematic diagram of the assembly of a blood pumping power source and a ventricular assist blood pumping cannula disclosed in an embodiment of the present invention
  • FIG6 is a schematic diagram of the structure of a blood pumping power source in a ventricular assist device disclosed in an embodiment of the present invention.
  • FIG. 7 is a schematic diagram of the structure of the impeller in the blood pumping power source disclosed in an embodiment of the present invention.
  • cannula for ventricular assist pumping 101. cannula body; 102. blood-conducting hose; 103. head tubular joint; 104. guide head; 105. blood inlet; 106. tail tubular joint; 107. bleeding outlet; 108. elastic hose; 109. metal ring; 110. guide cone; 111. developing ring; 112. pressure sensor;
  • Ventricular assist device 201. Blood pumping power source; 202. Impeller; 203. Motor; 204. Impeller shaft; 205. Blades.
  • One of the purposes of the present invention is to provide a cannula for ventricular assist pumping, mainly to solve the problem that the force between the existing cannula head and the ventricular inner wall is roughly judged entirely by the doctor's feel, experience, or three-dimensional mapping system, which has poor reliability and easily increases surgical risks.
  • Another object of the present invention is to provide a ventricular assist device to mainly solve the problem that the force between the existing catheter head and the inner wall of the ventricle is roughly judged entirely by the doctor's feel, experience, or three-dimensional mapping system, which has poor reliability and easily increases surgical risks.
  • this embodiment provides a cannula 100 for ventricular assist blood pumping, which includes a cannula body 101 and a pressure detection device.
  • the head of the cannula body 101 is provided with a blood inlet 105, and the tail of the cannula body 101 is provided with a blood outlet 107.
  • the head of the cannula body 101 is used to be inserted into the left ventricle of the heart, and the tail of the cannula body 101 is used to be connected to the aorta outside the heart.
  • the cannula body 101 is used to be connected to the blood pumping power source 201 to guide the blood of the left ventricle of the heart into the aorta outside the heart to achieve ventricular assist blood pumping.
  • the above-mentioned pressure detection device is arranged at the head of the cannula body 101, and is located on the side of the blood inlet 105 away from the tail of the cannula body 101. The pressure detection device is used to detect the pressure on the head of the cannula body 101.
  • the cannula body 101 specifically includes a blood-exiting hose 102, a head tubular joint 103, and a tail tubular joint 106.
  • the axial first end of the head tubular joint 103 is connected to the head (i.e., the liquid inlet end) of the blood-exiting hose 102.
  • the axial second end of the head tubular joint 103 is provided with a guide head 104.
  • the head tubular joint 103 has a blood inlet 105 on the side wall between the axial first end and the axial second end.
  • the aforementioned pressure detection device is arranged on the guide head 104, specifically, arranged outside the guide head 104.
  • the axial first end of the tail tubular joint 106 is connected to the tail (i.e., the liquid outlet end) of the blood-exiting hose 102.
  • the axial second end of the tail tubular joint 106 is used to connect to the blood pumping power source 201.
  • the tail tubular joint 106 has a bleeding port 107 on the side wall between the axial first end and the axial second end. As for the cannula body 101 as a whole, the aforementioned blood inlet 105 and bleeding port 107 are both opened on its side wall.
  • the blood-collecting hose 102 includes an elastic hose 108 and a hose frame, and the hose frame is embedded in the tube wall of the elastic hose 108, that is, the inner and outer sides of the hose frame are covered with a hose structure.
  • the hose frame can be in the following two forms:
  • the hose skeleton includes a plurality of metal rings 109 arranged at intervals along the axial direction of the elastic hose 108.
  • the material of the elastic hose 108 is preferably a soft biocompatible material such as TPU (thermoplastic polyurethane elastomer rubber) or TPE (thermoplastic elastomer material).
  • the metal ring 109 is preferably a stainless steel ring, a nickel-titanium alloy ring or a platinum-iridium alloy ring.
  • the elastic hose 108 and the metal ring 109 are combined by refolw and heat shrink laminar flow, so that the shaft of the blood-collecting hose 102 is flexible and has good controllability, which increases the position and stability of the head of the cannula body 101.
  • the hose skeleton is made of a metal sheet spirally wound, similar to a spring structure.
  • the material of the elastic hose 108 is preferably a soft biocompatible material such as TPU (thermoplastic polyurethane elastomer rubber) or TPE (thermoplastic elastomer material).
  • the metal sheet is preferably stainless steel, nickel-titanium alloy or platinum-iridium alloy.
  • the elastic hose 108 and the spiral hose skeleton are combined by refolw and heat shrink laminar flow, so that the shaft of the blood-collecting hose 102 is flexible and has good controllability, which increases the position and stability of the head of the cannula body 101.
  • the tail tubular joint 106 and the blood-exiting hose 102 are connected together by curing with hot-flow glue, and a curing ring is formed during curing to smoothly transition the connection between the tail tubular joint 106 and the blood-exiting hose 102.
  • the head tubular joint 103 and the blood-exiting hose 102 can also be connected together by curing with hot-flow glue, and a curing ring is formed at the connection.
  • the blood-collecting hose 102 is bent at 1/3 of the length of the head, so that the head (i.e., the liquid inlet end) and the tail (i.e., the liquid outlet end) of the blood-collecting hose 102 are arranged at an angle ⁇ .
  • the angle ⁇ is the angle between the 1/3 length section of the head and the 2/3 length section of the tail of the blood-collecting hose 102, and the angle ⁇ is preferably between 35° and 55°.
  • the blood-collecting hose 102 is bent at about 45° ⁇ 10° at one-third of the length to simulate the shape of the connection between the blood vessel and the heart, and to avoid adverse reactions such as damage to the blood vessel wall and the endocardium caused by the rigidity of the cannula.
  • the angle ⁇ can be specifically 35°, 45° or 55°.
  • the length of the blood-collecting hose 102 (excluding the axial length of the head tubular joint 103 and the tail tubular joint 106) is used as a reference, and the bend is located at 1/3 of the length from the head to the tail of the blood-collecting hose 102.
  • the length of the cannula body 101 (which is the sum of the axial lengths of the head tubular connector 103, the blood-collecting hose 102 and the tail tubular connector 106) is used as a reference, the above-mentioned bending at one-third of the axial length from the head to the tail is still applicable.
  • the guide head 104 is a round blunt head, which can prevent the cannula body 101 from damaging the internal organs when being inserted into the left atrium.
  • a guide cone 110 is arranged coaxially with the head tubular joint 103. The large end of the guide cone 110 is connected to the round blunt head, and the tip, i.e., the small end, is arranged toward the blood-conducting hose 102.
  • the outer wall of the head tubular joint 103 is evenly provided with a plurality of blood inlets 105, for example, three, along its circumference. The blood flow introduced by the blood inlet 105 first contacts the outer wall of the guide cone 110, and then flows to the blood-conducting hose 102 under the guidance of the tip of the guide cone 110.
  • the side wall of the diversion cone 110 can be set to an arc shape, that is, the side wall of the diversion cone 110 is in an arc transition from the large end of the diversion cone 110 to the small end of the diversion cone 110, which can buffer the blood flow rate while draining blood and reduce the patient's heart discomfort during ventricular assist pumping.
  • the pressure detection device adopts the form of a combination of a developing ring 111 and a pressure sensor 112 .
  • the developing ring 111 is sleeved on the outside of the guide head 104
  • the pressure sensor 112 is arranged on the guide head 104 .
  • the tail tubular connector 106 of the ventricular auxiliary pumping cannula 100 When in use, the tail tubular connector 106 of the ventricular auxiliary pumping cannula 100 is connected to the aorta outside the heart and connected to the blood pumping power source, and the head tubular connector 103 is inserted into the left ventricle; when the patient's heart pumping capacity is insufficient, the blood pumping power source is started, and the left ventricle blood can be pumped in through the blood inlet 105 on the head tubular connector 103, and then flow through the blood running hose 102 and the bleeding port 107 of the tail tubular connector 106 to enter the aorta outside the heart, and then flow to the whole body.
  • the guide head 104 of the cannula body 101 as the front end of the whole cannula, must not be heavily pressed on the inner wall of the left ventricle when pumping blood, and the position of the cannula body 101 in the heart and the contact of the guide head 104 with the inner wall of the heart can be judged by the developing ring 111 and the pressure sensor 112.
  • the present technical solution removes the pigtail-shaped flexible protrusion on the original cannula, and adopts a developing ring 111 and a pressure sensor 112 to replace manual experience, so as to quantify the pressure sensed by the cannula, and accurately display the lateral partial pressure and axial partial pressure of the cannula head in real time, so as to avoid the blood inlet from fitting against the inner wall of the heart during blood pumping; at the same time, the present technical solution removes the pigtail-shaped flexible protrusion on the cannula head, so as to avoid the formation of blood clots during auxiliary blood pumping.
  • This embodiment proposes a ventricular assist device 200, including a blood pumping power source 201 and a ventricular assist blood pumping cannula 100 as disclosed in the first embodiment, wherein the blood pumping power source 201 is arranged at the second end of the tail tubular joint 106 in the ventricular assist blood pumping cannula 100.
  • the above-mentioned blood pumping power source is preferably a blade-type blood pump, specifically including an impeller 202 and a motor 203, wherein the impeller 202 is arranged in the tail tubular joint 106, and the impeller 202 includes an impeller shaft 204 coaxially arranged with the tail tubular joint 106 and a plurality of blades 205 arranged on the outer periphery of the impeller shaft 204; the output end of the motor 203 is connected to the impeller shaft 204, and the second end of the tail tubular joint 106 and the impeller shaft 204 are both sealed and docked with the housing of the motor 203 to ensure the sealing of the electrical components, and prevent human tissue fluid (blood, stagnant water, etc.) from entering the electrical appliances, accelerating corrosion, and reducing service life.
  • human tissue fluid blood, stagnant water, etc.
  • the impeller shaft 204 is preferably a tapered impeller shaft, and the large end of the tapered impeller shaft is disposed toward the motor 203, and the small end of the tapered impeller shaft is disposed toward the blood-collecting hose 102.
  • the impeller shaft 204 has a small and pointed front end and a large and thick rear end, and is in a gradually enlarged and relaxed state, which ensures that the front end does not damage blood cells when drawing blood, and that the rear end can draw blood at a larger flow rate.
  • the side wall of the impeller shaft 204 transitions in an arc from the tip to the thick end.
  • any blade 205 close to the small end of the conical impeller shaft is spirally deflected.
  • the blades 205 on the periphery of the impeller shaft 204 are evenly distributed along the circumference of the impeller shaft 204.
  • three blades 205 can be evenly arranged on the periphery of the impeller shaft 204 along its circumference.
  • the motor 203 is a conventional motor, and its structure includes a motor housing, a motor coil, a magnet, a motor shaft, a printed circuit board (PCB), a circuit board bracket, a bearing, etc., wherein the large end of the impeller shaft 204 is connected to the motor shaft, and the motor housing is preferably a cylindrical housing, and one axial end thereof can be plugged into the tail end of the tail tubular joint 106 through the top connector of the housing, and in order to achieve sealing, a sealing ring can be provided between the top connector of the housing and the tail tubular joint 106.
  • PCB printed circuit board
  • the other axial end of the motor housing will be connected to the power supply and signal line when in use, and is used to control the opening and closing of the motor and control the cannula head to collect pressure information.
  • the developing ring 111 and the pressure sensor 112 in the pressure detection device can be controlled by wire or by wireless.
  • the developing ring 111 and the pressure sensor 112 are both controlled by wire, they are both electrically connected to the power supply, the controller and other components through the signal line.
  • the signal line connected to the developing ring 111 and the pressure sensor 112 is inserted and stored in the blood-exiting hose 102, and can be fixed to the inner wall of the blood-exiting hose 102 through the relevant wire harness fixing structure.
  • the inside of the impeller shaft 204 can also be hollowed out to form a threading space connected to the blood-exiting hose 102.
  • the signal line connected to the developing ring 111 and the pressure sensor 112 passes through the inside of the blood-exiting hose 102, the inside of the impeller shaft 204 and the inside of the motor housing in turn, and finally passes out through the tail end of the motor housing.
  • This design allows the signal line, the power supply line, etc. to be inserted into the ventricular assist device 200, which not only ensures the neatness of the overall line of the device, but also facilitates the implantation of the ventricular assist device 200 into the body.
  • the guide head 104 of the cannula body 101 shall not press heavily on the inner wall of the left ventricle when pumping blood, and the position of the cannula body 101 in the heart and the contact of the guide head 104 with the inner wall of the heart can be judged by the developing ring 111 and the pressure sensor 112.
  • the present technical solution removes the pigtail-shaped flexible protrusion on the original cannula, and adopts a developing ring 111 and a pressure sensor 112 to replace manual experience, so as to quantify the pressure sensed by the cannula, and accurately display the lateral partial pressure and axial partial pressure of the cannula head in real time, so as to avoid the blood inlet from fitting against the inner wall of the heart during blood pumping; at the same time, the present technical solution removes the pigtail-shaped flexible protrusion on the cannula head, so as to avoid the formation of blood clots during auxiliary blood pumping.

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  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
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Abstract

L'invention concerne une canule (100) pour le pompage d'assistance ventriculaire, laquelle canule concerne le domaine des instruments médicaux. Dans la canule, la partie terminale est conçue pour être reliée à l'aorte externe au cœur et reliée à une source d'alimentation de pompage (201), et la partie tête est conçue pour être insérée dans le ventricule gauche. Lorsque la fonction de pompe cardiaque d'un patient est inadéquate, la source d'alimentation de pompage (201) est démarrée, de telle sorte que le sang provenant du ventricule gauche peut être pompé à travers une entrée de sang (105), puis s'écoule séquentiellement à travers un corps de canule (102) et une sortie de sang (107) pour entrer dans l'aorte externe au cœur, puis s'écoule partout dans le corps. Dans le dispositif, une saillie flexible en forme de queue de cochon sur la partie tête d'une canule d'origine est omise, et un dispositif de mesure de pression peut être utilisé à la place d'une expérience manuelle pour quantifier la pression induite par la canule (100) et afficher avec précision la pression partielle latérale et la pression partielle axiale de la partie tête de la canule en temps réel, ce qui empêche l'entrée de sang (105) de s'ajuster avec la paroi interne du cœur pendant un processus de pompage et est favorable à l'amélioration de l'effet de pompage assisté, et peut également éviter la formation de caillots sanguins pendant le processus de pompage assisté.
PCT/CN2022/131669 2022-11-14 2022-11-14 Canule pour pompage d'assistance ventriculaire, et dispositif d'assistance ventriculaire WO2024103207A1 (fr)

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PCT/CN2022/131669 WO2024103207A1 (fr) 2022-11-14 2022-11-14 Canule pour pompage d'assistance ventriculaire, et dispositif d'assistance ventriculaire

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PCT/CN2022/131669 WO2024103207A1 (fr) 2022-11-14 2022-11-14 Canule pour pompage d'assistance ventriculaire, et dispositif d'assistance ventriculaire

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US20150080743A1 (en) * 2012-04-27 2015-03-19 Abiomed Europe Gmbh Intravascular rotary blood pump
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CN110404128A (zh) * 2019-07-18 2019-11-05 张海军 有反馈功能的无极变速自供能人工心脏辅助装置
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