WO2024047361A3 - Fluid transfer system, apparatus and methods for bioprocessing - Google Patents

Fluid transfer system, apparatus and methods for bioprocessing Download PDF

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Publication number
WO2024047361A3
WO2024047361A3 PCT/GB2023/052262 GB2023052262W WO2024047361A3 WO 2024047361 A3 WO2024047361 A3 WO 2024047361A3 GB 2023052262 W GB2023052262 W GB 2023052262W WO 2024047361 A3 WO2024047361 A3 WO 2024047361A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
air
connection portion
fluid connection
consumable
Prior art date
Application number
PCT/GB2023/052262
Other languages
French (fr)
Other versions
WO2024047361A2 (en
Inventor
Dan STRANGE
Leo STEENSON
Ryan ROBERTS
Peter Crossley
Paul Crisp
Ed STONE
William DEEKS
Original Assignee
Cellular Origins Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2212684.1A external-priority patent/GB202212684D0/en
Priority claimed from GBGB2212685.8A external-priority patent/GB202212685D0/en
Priority claimed from GBGB2307961.9A external-priority patent/GB202307961D0/en
Priority claimed from GBGB2307963.5A external-priority patent/GB202307963D0/en
Priority claimed from GBGB2307962.7A external-priority patent/GB202307962D0/en
Application filed by Cellular Origins Limited filed Critical Cellular Origins Limited
Publication of WO2024047361A2 publication Critical patent/WO2024047361A2/en
Publication of WO2024047361A3 publication Critical patent/WO2024047361A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps

Abstract

A device for collecting a fluid sample from a fluid-containing consumable in a bioprocessing system, the consumable having a tube fluidly attached thereto, the device comprising: a fluid connection portion configured to be connected to the tube of a fluid-containing consumable, and to enable pumping of fluid or air through the device; and an air input portion configured to allow sterile air to be supplied to the device; a sampling portion connected to the fluid connection portion, wherein during pumping into the device, the sampling portion is configured to receive a fluid sample from the consumable via the fluid connection portion; a bypass tube having a first end connected to the fluid connection portion and a second end connected to the air input portion, wherein the bypass tube is configured to receive air supplied from the air input portion and direct the air out of the device via the fluid connection portion without passing through the sampling portion, whereby to purge fluid from the tube connected to the consumable; and means for restricting fluid flow through each of the sampling portion and bypass tube, such that fluid being pumped into the fluid connection portion passes only into the sampling portion and air pumped out of the fluid connection portion passes only through the bypass tube.
PCT/GB2023/052262 2022-08-31 2023-08-31 Fluid transfer system, apparatus and methods for bioprocessing WO2024047361A2 (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
GBGB2212684.1A GB202212684D0 (en) 2022-08-31 2022-08-31 Automated system for bioprocessing
GBGB2212685.8A GB202212685D0 (en) 2022-08-31 2022-08-31 Automated fill/ finish system
GB2212685.8 2022-08-31
GB2212684.1 2022-08-31
GBGB2307961.9A GB202307961D0 (en) 2023-05-26 2023-05-26 Fluid transfer system, apparatus and methods for bioprocessing
GB2307961.9 2023-05-26
GB2307963.5 2023-05-26
GB2307962.7 2023-05-26
GBGB2307963.5A GB202307963D0 (en) 2023-05-26 2023-05-26 Fluid transfer system, apparatus and methods for bioprocessing
GBGB2307962.7A GB202307962D0 (en) 2023-05-30 2023-05-30 Fluid transfer system, apparatus and methods for bioprocessing

Publications (2)

Publication Number Publication Date
WO2024047361A2 WO2024047361A2 (en) 2024-03-07
WO2024047361A3 true WO2024047361A3 (en) 2024-04-11

Family

ID=88017728

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2023/052262 WO2024047361A2 (en) 2022-08-31 2023-08-31 Fluid transfer system, apparatus and methods for bioprocessing

Country Status (1)

Country Link
WO (1) WO2024047361A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270996B2 (en) * 2000-10-02 2007-09-18 Cannon Thomas F Automated bioculture and bioculture experiments system
US20140123775A1 (en) * 2012-11-05 2014-05-08 Bend Research, Inc. Fixed volume aseptic sampling valve for sampling from enclosed containers
WO2018148346A1 (en) * 2017-02-10 2018-08-16 Lonza Ltd. Cell culture system and method
US10190950B2 (en) * 2014-10-31 2019-01-29 General Electric Company Semi-automated sampling system for aseptic sampling
EP3926036A1 (en) * 2020-06-15 2021-12-22 ESTR Biosystems GmbH Tank for a bio-pharma process

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270996B2 (en) * 2000-10-02 2007-09-18 Cannon Thomas F Automated bioculture and bioculture experiments system
US20140123775A1 (en) * 2012-11-05 2014-05-08 Bend Research, Inc. Fixed volume aseptic sampling valve for sampling from enclosed containers
US10190950B2 (en) * 2014-10-31 2019-01-29 General Electric Company Semi-automated sampling system for aseptic sampling
WO2018148346A1 (en) * 2017-02-10 2018-08-16 Lonza Ltd. Cell culture system and method
EP3926036A1 (en) * 2020-06-15 2021-12-22 ESTR Biosystems GmbH Tank for a bio-pharma process

Also Published As

Publication number Publication date
WO2024047361A2 (en) 2024-03-07

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