WO2024018271A1 - Anti-spot, lightening and anti-wrinkle solution based on organic phase and aqueous phase - Google Patents
Anti-spot, lightening and anti-wrinkle solution based on organic phase and aqueous phase Download PDFInfo
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- WO2024018271A1 WO2024018271A1 PCT/IB2022/058117 IB2022058117W WO2024018271A1 WO 2024018271 A1 WO2024018271 A1 WO 2024018271A1 IB 2022058117 W IB2022058117 W IB 2022058117W WO 2024018271 A1 WO2024018271 A1 WO 2024018271A1
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- container
- solution
- skin
- ascorbic acid
- dissolve
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Definitions
- anti-spot, lightening and anti-wrinkle solution is based on organic phase and aqueous phase that uses these ingredients: Spirulina algae, Hydroquinone, Isotertinoin, Ascorbic acid, Mometasone and Ethanol, and it can be produced in two phases: laboratory and large scale (industrial).
- Active ingredient comprising a mixture of unsaturated dicarboxylic fatty acids, compositions comprising said ingredient and cosmetic or dermatological uses
- the ingredient comprises a mixture of unsaturated dicarboxylic acids comprising the Z and E isomers of at least one mono-unsaturated dicarboxylic C12-C24 acid, the concentration of the E isomer being of at least 25% by weight based on the total weight of Z and E isomers.
- the ingredient can be used to form cosmetic or dermatological compositions, in particular for lightening the skin, improving the clarity and unification of the skin complexion.
- the present invention relates to the uses of swertiamarin or of a plant extract enriched with swertiamarin, for stimulating the formation or regeneration of the epidermis and/or for stimulating the metabolism of the dermis mainly in the cosmetics field.
- Immediate effect anti-wrinkle composition based on an aqueous dispersion, of at least one mineral filler
- the invention relates to a cosmetic composition having an immediate anti-wrinkle effect, containing an effective amount of at least one mineral filler, with the exclusion of any mixed silicate, the mineral filler being in the form of colloid particles in a stable dispersion in an aqueous medium.
- the invention also relates to using such a filler as a tensing agent in and/or for preparing a cosmetic composition.
- a skin lightening composition for lightening the natural skin color of a user, and for treating disorders of hyperpigmentation.
- the active ingredient is methyl sulfonyl methane (MSM), a naturally occurring sulfur compound which may be safely administered topically or orally and which is highly effective for decreasing the ratio of dark melanin to light melanin, and thereby lightening the skin color of a user.
- the skin lightening composition additionally comprises a liquid solution or a cosmetic carrier such as a cream, a lotion, or a gel, for ease of topical application. Additionally, the skin lightening composition is provided in liquid or solid form for oral ingestion.
- Topical preparations of the skin lightening composition contain MSM in an amount equal to approximately 1 to 20 weight percent MSM relative to the weight of the entire composition.
- Orally ingestible preparations of the skin lightening composition contain approximately 200 mg to 5000 mg MSM per serving.
- Skin lightening additives and skin lightening compositions having at least one of a heterosubstituted, saturated or unsaturated aliphatic acid are described.
- the compositions are suitable for topical application and may comprise 12-hydroxystearic acid, ricinoleic acid or both.
- the present invention relates to a new type of anti-wrinkle cosmetic product, which has a different composition with respect to the cosmetic products used hitherto, and includes a small number of components permitting to obtain an excellent and complete anti-wrinkle and Anti-spot, lightening effects on the skin to which it is applied.
- the sketch seen above is the anti-spot and anti-wrinkle solution based on organic phase and aqueous phase, which removes skin wrinkles and spot on skin and body fast and without side effects.
- This solution consists of: 5% of Spirulina algae powder, 4% of Hydroquinone, 0.05% of Isotretinoin, 5% of Ascorbic acid, 0.1% of Mometasone powder, 100cc of 70% Ethanol.
- Skin is always exposed to external stimuli. Consequently, wrinkles, flabbiness, dullness and pigmentation occur in the skin with age, and the properties of the skin change. This is called skin aging.
- the mechanism of aging is on the way of clarification and not yet cleared.
- the skin is the outermost layer of a living body to play a protective role. Therefore, it is thought that the accumulation of damages caused by environmental factors is largely responsible for the skin aging. In particular, it is thought that an ultraviolet light is the most serious environmental factor.
- free radicals and active oxygen that are produced by an ultraviolet light induce not only acute inflammation such as a sunburn but also photoaging resulting from chronic exposure. It is thought that the free radicals and active oxygen generated by an ultraviolet light will damage and denature the crosslinks of elastic protein such as collagen and elastin which is a constituent of a corium, will inactivate the antioxidant enzymes such as SOD, and will cause the peroxidation of cell membrane lipid, thereby resulting in wrinkles.
- the sketch seen above is the anti-spot and anti-wrinkle solution based on organic phase and aqueous phase, which removes skin wrinkles and spot on skin and body fast and without side effects.
- This solution consists of: 5% of Spirulina algae powder, 4% of Hydroquinone, 0.05% of Isotretinoin, 5% of Ascorbic acid, 0.1% of Mometasone powder, 100cc of 70% Ethanol.
- Proteins are vital for health, skincare and haircare. Some amino acids are essential for producing collagen and maintaining skin elasticity. Also, by providing body’s necessary proteins, producing collagen becomes easier and hair grows faster and better. Spirulina contains more than 60% of proteins, which is the highest amount of protein in the world and can provide all of the essential amino acids for the body. Spirulina algae is a greenwater algae with fabulous features that can be a real lifesaver for health and beauty fans. Spirulina contains lots of protein, vitamin, minerals and antioxidants and can solve hair and skin cellular and nutritional deficiencies efficiently.
- Spirulina algae absorbs heavy metals and removes them from body and skin cells. This algae is full of Chlorophyll, which is one of the best natural cleansers and can be effective in toxin and heavy metals’ removal and give you a smoother and brighter skin.
- Spirulina contains a fatty acid called gamma-Linolenic acid (GLA for short), which helps body overcome inflammation. This fatty acid helps in maintaining skin integrity and fights with inflammation and skin conditions like Atopic dermatitis (eczema).
- GLA gamma-Linolenic acid
- Spirulina contains powerful antioxidants that can easily neutralize free radicals and protect body skin.
- Spirulina slows down the aging process by neutralizing free radicals, removing toxins and heavy metals, and increasing cellular metabolism.
- One of the amazing antioxidants in Spirulina is Phycocyanin which is blue and has an outstanding effect on cell renewal and skin repair.
- Spirulina is rich with Vitamin A, E, and B12 and can cure damaged and loose skin, rejuvenate and brighten skin, and prevent aging process and free radical damaging skin. Spirulina’s vitamins help the body produce new and healthy cells faster and provides you with a younger and brighter skin.
- Spirulina strengthens body’s immune system. So, by strengthening the immune system, it naturally helps the skin which is the most external layer of the body and is exposed to all types of pollution and damages remain healthier and brighter. Spirulina has detoxification and cleansing effect which can help removing dark and brown skin spots.
- Spirulina algae is a powerful anti-bacterial and anti-viral, and can disinfect and remove harmful bacteria that cause acne and pimples. Spirulina can even help remove warts and is an easy cure for warts.
- Hydroquinone makes the skin smoother and brighter.
- Hydroquinone can brighten the skin by synthesis and controlling Melanin.
- This element is usually used in curing hyperpigmentation diseases such as freckles, inflammation, skin redness, .
- This element can be used on its own but it is usually found in combination with Alpha hydroxyl acid, Corticosteroids, Retinoids, Sunscreens.
- Isotretion is a retinoid that when, administered in pharmacologic dosages inhibits sebaceous gland function and keratinization. The exact mechanism of action of isotretinoin is unknown.
- Ascorbic acid is a vitamin and a nutrition that is soluble in water and is often used in cosmetic formulation, skincare, haircare and personal care products. It is a natural skin builder that is found in derm and epiderm in high levels. The level of Vitamin C in epiderm is higher than in derm, even though the concentration of this vitamin in both layers is approximately same as other antioxidants that are soluble in water, including Uric acid and Glutathione. But aging decreases levels of Vitamin C in derm and epiderm. Being exposed to high levels of ultraviolet rays or pollutants can also decrease the amount of the vitamin. Ascorbic acid on skin surface usually transfers through blood flow.
- Ascorbic acid Although the natural form of Ascorbic acid is effective for local treatment, stable artificial derivations such as Ascorbat phosphate are used because of their limited penetration and effect on the skin.in addition, Ascorbic acid due to its antioxidant properties prevents the oxidation of hydroquinon and isotretinoin. As a result, it increases the half-life of these materials.
- Mometasone is a powerful steroidal anti-inflammatory drug, used for treating systemic symptoms of inflammation or itchiness in chronic or acute malfunctions that react to corticosteroids, especially where the skin is thick.
- Mometasone cream and ointment are prescribed in treating some skin diseases such as Dermatitis, Psoriasis, and Lichen planus.
- Mometasone ointment is a local corticosteroid which functions by decreasing inflammatory reactions and correcting immune system responses in body.
- Mometasone ointment (for skin), is a local steroid that functions by decreasing the effect of chemicals in body which cause inflammation, redness and swelling.in this way,it prevents the side effects of hydroquinone and isotretinoin.
- Alcohol has an anti-bacterial feature which is why it is used for cleaning wounds and disinfecting surfaces. Also, you can usually see alcohol as the ingredient on hand sanitizers. When alcohol gets on the skin, it dissolves bacteria and disinfects the spot. On the other hand, alcohol vapors fast and is therefore used for medical purposes and injections as well.
- Container 1 and 2 are connected to container 3 by pipes and pumps.
- This solution is produced in two industrial and laboratory phases. For example, how to make it in a laboratory sample is as follows: First we dissolve the soluble elements in water during the aqueous phase (5g of Ascorbic acid, 100mg of Mometasone, 5g of Spirulina powder, dissolved in 70cc of distillated water in room temperature) and also we dissolve organic phase elements such as: Hydroquinone 4gr, Isotertinoin 50 mg in 30cc of Ethanol and then we combine both solutions to make it ready for packaging.
- aqueous phase 5g of Ascorbic acid, 100mg of Mometasone, 5g of Spirulina powder, dissolved in 70cc of distillated water in room temperature
- organic phase elements such as: Hydroquinone 4gr, Isotertinoin 50 mg in 30cc of Ethanol
- This solution can be used in all beauty centers, hair salons and even medical centers, and all ages and people can use this solution.
Abstract
The production process of anti-spot,lightening and anti-wrinkle solution is based on organic phase and aqueous phase that uses these ingredients: Spirulina algae, Hydroquinone, Isotertinoin, Ascorbic acid, Mometasone and Ethanol, and it can be produced in two phases: laboratory and large scale (industrial).
Description
The production process of anti-spot, lightening and anti-wrinkle solution is based on organic phase and aqueous phase that uses these ingredients: Spirulina algae, Hydroquinone, Isotertinoin, Ascorbic acid, Mometasone and Ethanol, and it can be produced in two phases: laboratory and large scale (industrial).
A61Q 19/08
Active ingredient comprising a mixture of unsaturated dicarboxylic fatty acids, compositions comprising said ingredient and cosmetic or dermatological uses
United States Patent 9918916
The ingredient comprises a mixture of unsaturated dicarboxylic acids comprising the Z and E isomers of at least one mono-unsaturated dicarboxylic C12-C24 acid, the concentration of the E isomer being of at least 25% by weight based on the total weight of Z and E isomers. The ingredient can be used to form cosmetic or dermatological compositions, in particular for lightening the skin, improving the clarity and unification of the skin complexion.
COSMETIC USES OF SWERTIAMARIN
United States Patent Application 20170020796
The present invention relates to the uses of swertiamarin or of a plant extract enriched with swertiamarin, for stimulating the formation or regeneration of the epidermis and/or for stimulating the metabolism of the dermis mainly in the cosmetics field.
Immediate effect anti-wrinkle composition, based on an aqueous dispersion, of at least one mineral filler
United States Patent 6896889
The invention relates to a cosmetic composition having an immediate anti-wrinkle effect, containing an effective amount of at least one mineral filler, with the exclusion of any mixed silicate, the mineral filler being in the form of colloid particles in a stable dispersion in an aqueous medium. The invention also relates to using such a filler as a tensing agent in and/or for preparing a cosmetic composition.
Skin lightening composition
United States Patent Application 20050226827
A skin lightening composition for lightening the natural skin color of a user, and for treating disorders of hyperpigmentation. The active ingredient is methyl sulfonyl methane (MSM), a naturally occurring sulfur compound which may be safely administered topically or orally and which is highly effective for decreasing the ratio of dark melanin to light melanin, and thereby lightening the skin color of a user. The skin lightening composition additionally comprises a liquid solution or a cosmetic carrier such as a cream, a lotion, or a gel, for ease of topical application. Additionally, the skin lightening composition is provided in liquid or solid form for oral ingestion. Topical preparations of the skin lightening composition contain MSM in an amount equal to approximately 1 to 20 weight percent MSM relative to the weight of the entire composition. Orally ingestible preparations of the skin lightening composition contain approximately 200 mg to 5000 mg MSM per serving.
Method for lightening skin
United States Patent 9227090
Skin lightening additives and skin lightening compositions having at least one of a heterosubstituted, saturated or unsaturated aliphatic acid are described. The compositions are suitable for topical application and may comprise 12-hydroxystearic acid, ricinoleic acid or both.
At present time, many cosmetic products are used for being applied particularly on face skin in which wrinkles are present, in order to stretch it make it smoother. However, these products do not eliminate completely wrinkles and bags, in that this effect can be obtained only with one or more surgical operations. The present invention relates to a new type of anti-wrinkle cosmetic product, which has a different composition with respect to the cosmetic products used hitherto, and includes a small number of components permitting to obtain an excellent and complete anti-wrinkle and Anti-spot, lightening effects on the skin to which it is applied. The sketch seen above is the anti-spot and anti-wrinkle solution based on organic phase and aqueous phase, which removes skin wrinkles and spot on skin and body fast and without side effects. This solution consists of: 5% of Spirulina algae powder, 4% of Hydroquinone, 0.05% of Isotretinoin, 5% of Ascorbic acid, 0.1% of Mometasone powder, 100cc of 70% Ethanol.
Skin is always exposed to external stimuli. Consequently, wrinkles, flabbiness, dullness and pigmentation occur in the skin with age, and the properties of the skin change. This is called skin aging. The mechanism of aging is on the way of clarification and not yet cleared. The skin is the outermost layer of a living body to play a protective role. Therefore, it is thought that the accumulation of damages caused by environmental factors is largely responsible for the skin aging. In particular, it is thought that an ultraviolet light is the most serious environmental factor.
It is known that free radicals and active oxygen that are produced by an ultraviolet light induce not only acute inflammation such as a sunburn but also photoaging resulting from chronic exposure. It is thought that the free radicals and active oxygen generated by an ultraviolet light will damage and denature the crosslinks of elastic protein such as collagen and elastin which is a constituent of a corium, will inactivate the antioxidant enzymes such as SOD, and will cause the peroxidation of cell membrane lipid, thereby resulting in wrinkles.
Conventionally, dermatological anti-wrinkle agents and cosmetics are proposed for the purposes of preventing and improving the deformation of skin due to aging. The sketch seen above is the anti-spot and anti-wrinkle solution based on organic phase and aqueous phase, which removes skin wrinkles and spot on skin and body fast and without side effects. This solution consists of: 5% of Spirulina algae powder, 4% of Hydroquinone, 0.05% of Isotretinoin, 5% of Ascorbic acid, 0.1% of Mometasone powder, 100cc of 70% Ethanol.
The sketch seen above is the anti-spot and anti-wrinkle solution based on organic phase and aqueous phase, which removes skin wrinkles and spot on skin and body fast and without side effects. This solution consists of: 5% of Spirulina algae powder, 4% of Hydroquinone, 0.05% of Isotretinoin, 5% of Ascorbic acid, 0.1% of Mometasone powder, 100cc of 70% Ethanol.
We will get to know more about each element used in this solution and the process of making the solution in the industrial and laboratory phase will be explained.
Spirulina algae
Proteins are vital for health, skincare and haircare. Some amino acids are essential for producing collagen and maintaining skin elasticity. Also, by providing body’s necessary proteins, producing collagen becomes easier and hair grows faster and better. Spirulina contains more than 60% of proteins, which is the highest amount of protein in the world and can provide all of the essential amino acids for the body. Spirulina algae is a greenwater algae with fabulous features that can be a real lifesaver for health and beauty fans. Spirulina contains lots of protein, vitamin, minerals and antioxidants and can solve hair and skin cellular and nutritional deficiencies efficiently.
Body cells usually get contaminated by heavy metals due to air pollution, unhealthy diet and consumption of different chemicals, which causes cell destruction and various diseases. Spirulina algae absorbs heavy metals and removes them from body and skin cells. This algae is full of Chlorophyll, which is one of the best natural cleansers and can be effective in toxin and heavy metals’ removal and give you a smoother and brighter skin. Also, Spirulina contains a fatty acid called gamma-Linolenic acid (GLA for short), which helps body overcome inflammation. This fatty acid helps in maintaining skin integrity and fights with inflammation and skin conditions like Atopic dermatitis (eczema).
Increase of free radicals on skin due to sun rays, air pollution and unhealthy diet, causes wrinkles, aging and skin darkening. Spirulina contains powerful antioxidants that can easily neutralize free radicals and protect body skin.
Spirulina slows down the aging process by neutralizing free radicals, removing toxins and heavy metals, and increasing cellular metabolism. One of the amazing antioxidants in Spirulina is Phycocyanin which is blue and has an outstanding effect on cell renewal and skin repair.
Spirulina is rich with Vitamin A, E, and B12 and can cure damaged and loose skin, rejuvenate and brighten skin, and prevent aging process and free radical damaging skin. Spirulina’s vitamins help the body produce new and healthy cells faster and provides you with a younger and brighter skin.
Spirulina strengthens body’s immune system. So, by strengthening the immune system, it naturally helps the skin which is the most external layer of the body and is exposed to all types of pollution and damages remain healthier and brighter. Spirulina has detoxification and cleansing effect which can help removing dark and brown skin spots.
Spirulina algae is a powerful anti-bacterial and anti-viral, and can disinfect and remove harmful bacteria that cause acne and pimples. Spirulina can even help remove warts and is an easy cure for warts.
Hydroquinone
Hydroquinone makes the skin smoother and brighter. One of the reasons that causes spots on the skin, is factors that trigger the synthesis of Melanin, such as sunlight and ultraviolet rays. Hydroquinone can brighten the skin by synthesis and controlling Melanin. This element is usually used in curing hyperpigmentation diseases such as freckles, inflammation, skin redness, . This element can be used on its own but it is usually found in combination with Alpha hydroxyl acid, Corticosteroids, Retinoids, Sunscreens.
Isotretinoin
Isotretion is a retinoid that when, administered in pharmacologic dosages inhibits sebaceous gland function and keratinization. The exact mechanism of action of isotretinoin is unknown.
Clinical impnovement in nodular acne occurs in association with a reduction in sebum secretion as a result, spots left by acne will disappear gradually afte topical use of isotretinoin.
Ascorbic acid
The effect of Ascorbic acid on the skin is quite clear. This vitamin is essential for the formation of blood vesselss, cartilage, muscles and collagen in bones. It is also vital for the body’s recovery. Ascorbic acid is a vitamin and a nutrition that is soluble in water and is often used in cosmetic formulation, skincare, haircare and personal care products. It is a natural skin builder that is found in derm and epiderm in high levels. The level of Vitamin C in epiderm is higher than in derm, even though the concentration of this vitamin in both layers is approximately same as other antioxidants that are soluble in water, including Uric acid and Glutathione. But aging decreases levels of Vitamin C in derm and epiderm. Being exposed to high levels of ultraviolet rays or pollutants can also decrease the amount of the vitamin. Ascorbic acid on skin surface usually transfers through blood flow.
Special carrier proteins for the effect of Ascorbic acid on skin, are found in all layers of skin. Keratinocytes have a high capacity for transferring Ascorbic acid. Taking edible Vitamin C probably helps bringing levels of vitamin up, since epiderm does not have many blood vessels. However when the plasma vitamin C level is saturated, the concentration on the skin does not increase anymore, so you can enrich your skin with Vitamin C by applying creams locally. Absorption of Vitamin C by skin relies heavily on pH. Local effect of Ascorbic acid helps transferring epiderm to the skin layers beneath. Vitamin C stability in local solutions is a concern, because getting exposed to air, heat or light might gradually destruct it. Although the natural form of Ascorbic acid is effective for local treatment, stable artificial derivations such as Ascorbat phosphate are used because of their limited penetration and effect on the skin.in addition, Ascorbic acid due to its antioxidant properties prevents the oxidation of hydroquinon and isotretinoin. As a result, it increases the half-life of these materials.
Mometasone
Mometasone is a powerful steroidal anti-inflammatory drug, used for treating systemic symptoms of inflammation or itchiness in chronic or acute malfunctions that react to corticosteroids, especially where the skin is thick. Mometasone cream and ointment are prescribed in treating some skin diseases such as Dermatitis, Psoriasis, and Lichen planus. Mometasone ointment is a local corticosteroid which functions by decreasing inflammatory reactions and correcting immune system responses in body. Mometasone ointment (for skin), is a local steroid that functions by decreasing the effect of chemicals in body which cause inflammation, redness and swelling.in this way,it prevents the side effects of hydroquinone and isotretinoin.
Ethanol
Acne treatment with alcohol is only one of home remedies of acne and by simply searching in Google, you can find so many other solutions as well. Isopropyl is the technical term for alcohol and experts mostly use this term. Alcohol has an anti-bacterial feature which is why it is used for cleaning wounds and disinfecting surfaces. Also, you can usually see alcohol as the ingredient on hand sanitizers. When alcohol gets on the skin, it dissolves bacteria and disinfects the spot. On the other hand, alcohol vapors fast and is therefore used for medical purposes and injections as well.
Production steps in a small scale (Laboratory): First we dissolve the soluble elements in water during the aqueous phase (5g of Ascorbic acid, 100mg of Mometasone, 5g of Spirulina powder, dissolved in 70cc of distillated water in room temperature) and also we dissolve organic phase elements such as: Hydroquinone 4gr, Isotertinoin 50 mg in 30cc of Ethanol and then we combine both solutions to make it ready for packaging.
Production steps in an industrial scale: in order to produce this solution we need 3 containers made of stainless steel equipped with waterfront and mixer with at least 100 liter volume. Container 1 and 2 are connected to container 3 by pipes and pumps.
We collect 65 liter of distillated water with a temperature of 20 to 25 centigrade in container 1 and we turn the mixer on and then add 5kg of Ascorbic acid slowly. In the laboratory we dissolve 100g of Mometasone powder in 5 liters of water and add to container 1. Then 5kg of Spirulina algae powder is added to the container and we mix till the solution is monotonous.
Simultaneously, we collect 25 liters of pure Ethanol in container 2 and turn the mixer on in 20 to 25 centigrade and 4kg of Hydroquinone is slowly added. Then we dissolve 50g of Isotertinoin in 5 liters of pure Ethanol in laboratory phase and add it to the container to mix it up.
We transfer the solutions of container 1 and 2 by pump and silicon pipes to container 3 and mix it till we get a monotonous solution and get ready for packaging. The amount of ingredients can be different, considering the intensity of the disease and this way, the solution prevents side effects.
This solution makes the skin clear and fresh
This solution is the only anti-aging and wrinkle solution
This product is in solution form
Can be used by any person (both men and women)
Examples
This solution is produced in two industrial and laboratory phases. For example, how to make it in a laboratory sample is as follows: First we dissolve the soluble elements in water during the aqueous phase (5g of Ascorbic acid, 100mg of Mometasone, 5g of Spirulina powder, dissolved in 70cc of distillated water in room temperature) and also we dissolve organic phase elements such as: Hydroquinone 4gr, Isotertinoin 50 mg in 30cc of Ethanol and then we combine both solutions to make it ready for packaging.
This solution can be used in all beauty centers, hair salons and even medical centers, and all ages and people can use this solution.
Claims (7)
- The production process of anti-spot,lightening and anti-wrinkle solution is based on organic phase and aqueous phase that uses these ingredients: Spirulina algae, Hydroquinone, Isotertinoin, Ascorbic acid, Mometasone and Ethanol.
- According to claim 1, the amount of ingredients used in the laboratory scale is: Ascorbic acid 5g, Isotertinoin 50mg in 30cc of Ethanol.
- According to claim 2, the method of producing this solution in laboratory scale is explained: First, we dissolve the soluble elements in aqueous phase (we dissolve Ascorbic acid, Mometasone powder, Spirulina powder in the room temperature in distillated water) and also dissolve the soluble elements in organic phase, Hydroquinone, Isotertinoin in pure Ethanol and finally combine both aqueous and organic phase solutions and a monotonous solution is prepared for packaging.
- According to claim 1, steps of production in industrial scale goes this way: for this solution, 3 containers made of stainless steel and equipped with waterfront and mixer with a volume of at least 100 liters were provided and container 1 and 2 are connected to the container 3 by pipes and pumps.
- According to claim 4, 65 liter of distillated water with a temperature of 20 to 25 centigrade is collected in the first container. Then the mixer is turned on and 5kg of Ascorbic acid powder is added slowly. In laboratory, we dissolve 100g of Mometasone powder in 5 liter of water and add to the container 1. Then 5kg of Spirulina algae powder is also added to the container and we mix until we achieve a monotonous solution.
- According to claim 5, we collect 25 liter of pure Ethanol in the container 2 in 20 to 25 centigrade temperature, turn the mixer on and 4kg of Hydroquinone is added slowly. Then we dissolve 50g of Isotertinoin in 5 liter of pure Ethanol in laboratory phase and add it to the container and mix.
- According to claim 6, we transfer the solution of container 1 and 2 to container 3, using pump and silicone pipes and mix until we get a monotonous solution and finally get ready for packaging. The amount of ingredients can be different, considering the intensity of the disease and this way, the solution prevents side effects.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2022/058117 WO2024018271A1 (en) | 2022-08-30 | 2022-08-30 | Anti-spot, lightening and anti-wrinkle solution based on organic phase and aqueous phase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2022/058117 WO2024018271A1 (en) | 2022-08-30 | 2022-08-30 | Anti-spot, lightening and anti-wrinkle solution based on organic phase and aqueous phase |
Publications (1)
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| WO2024018271A1 true WO2024018271A1 (en) | 2024-01-25 |
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| PCT/IB2022/058117 WO2024018271A1 (en) | 2022-08-30 | 2022-08-30 | Anti-spot, lightening and anti-wrinkle solution based on organic phase and aqueous phase |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007103555A2 (en) * | 2006-03-08 | 2007-09-13 | Nuviance, Inc. | Transdermal drug delivery compositions and topical compositions for application on the skin |
| US20080063607A1 (en) * | 2003-08-04 | 2008-03-13 | Foamix Ltd | Oleaginous pharmaceutical and cosmetic foam |
| CN104224609A (en) * | 2013-06-23 | 2014-12-24 | 青岛道合生物科技有限公司 | Anti-wrinkle and anti-aging spirulina toner |
-
2022
- 2022-08-30 WO PCT/IB2022/058117 patent/WO2024018271A1/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080063607A1 (en) * | 2003-08-04 | 2008-03-13 | Foamix Ltd | Oleaginous pharmaceutical and cosmetic foam |
| WO2007103555A2 (en) * | 2006-03-08 | 2007-09-13 | Nuviance, Inc. | Transdermal drug delivery compositions and topical compositions for application on the skin |
| CN104224609A (en) * | 2013-06-23 | 2014-12-24 | 青岛道合生物科技有限公司 | Anti-wrinkle and anti-aging spirulina toner |
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