WO2024000456A1

WO2024000456A1 - Drug infusion apparatus, blockage detection method, detection system, and storage medium

Info

Publication number: WO2024000456A1
Application number: PCT/CN2022/102953
Authority: WO
Inventors: 黄浩科; 董俊
Original assignee: 深圳麦科田生物医疗技术股份有限公司
Priority date: 2022-06-30
Filing date: 2022-06-30
Publication date: 2024-01-04
Also published as: CN116096443A

Abstract

Provided are a drug infusion apparatus, a blockage detection method, a detection system, and a storage medium. The drug infusion apparatus comprises a housing (210), a motor (220), an infusion pipeline (230), as well as a first pump tablet (240), an extrusion pump tablet group (250) and a second pump tablet (260) sequentially arranged on an infusion pipeline (230) path and connected to the motor (220), a detection component (270) arranged on the infusion pipeline (230) path, and a data processor (280) connected to the detection component (270). The detection component (270) detects a state parameter of the infusion pipeline (230), and sends the detected state parameter to the data processor (280); the data processor (280) determines, according to a first state parameter detected by the detection component (270) at a first infusion stage and/or a second state parameter detected by the detection component (270) at a second infusion stage, that the infusion pipeline (230) is blocked.

Description

Drug infusion device, obstruction detection method, detection system and storage medium

Technical field

The present application relates to the technical field of infusion detection, and in particular, to a drug infusion device, an obstruction detection method, a detection system and a storage medium.

Background technique

With the increasing use of drug infusion devices, it is particularly necessary to monitor the obstruction of the infusion lines of drug infusion devices.

Pressure sensors are often used to detect obstructions in drug infusion devices, and two pressure sensors are usually required for detection.

However, in the related art, two pressure sensors are used for separate detection, making the detection device complex in structure, high in cost, and with a single detection method.

Contents of the invention

This application provides a drug infusion device, obstruction detection method, detection system and storage medium to solve the problems of complex structure, high cost and single detection method of the detection device.

According to one aspect of the present application, a drug infusion device is provided, including: a housing, a motor, an infusion pipeline, and a first pump piece, an extrusion piece, and an extrusion device that are sequentially arranged on the path of the infusion pipeline and connected to the motor. A pump tablet set and a second pump tablet, a detection component disposed on the infusion line path, and a data processor connected to the detection component;

The detection component detects the status parameter of the infusion line and sends the detected status parameter to the data processor;

The data processor determines the infusion line based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage. block.

According to another aspect of the present application, a method for detecting obstruction of a drug infusion device is provided, including: a data processor applied in the drug infusion device, the drug infusion device including a housing, a motor, and an infusion pipeline , as well as the first pump piece, the squeeze pump piece group and the second pump piece that are sequentially arranged on the infusion line path and connected to the motor, and the detection component is arranged on the infusion line path, and the a data processor that detects component connections;

The method includes: obtaining the status parameters of the infusion line detected by the detection component;

The infusion line is determined to be blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage.

According to another aspect of the present application, an obstruction detection system is provided, and the electronic device includes:

drug infusion devices;

The drug infusion device includes at least one processor; and

a memory communicatively connected to the at least one processor; wherein,

The memory stores a computer program that can be executed by the at least one processor, and the computer program is executed by the at least one processor, so that the at least one processor can execute the method described in any embodiment of the present application. A method for detecting obstruction of a drug infusion device.

According to another aspect of the present application, a computer-readable storage medium is provided. The computer-readable storage medium stores computer instructions, and the computer instructions are used to implement any of the embodiments of the present application when executed by a processor. A method for detecting obstruction of a drug infusion device.

The technical solution of the embodiment of the present application solves the problems of complex structure, poor operability, and high cost of the detection device by providing a method for detecting obstruction of a drug infusion device, and achieves cost reduction, simplified structure, and diverse detection methods. transformation purpose.

Description of drawings

Figure 1 is a working principle diagram of the obstruction detection of the drug infusion device provided in Embodiment 1 of the present application;

Figure 2a is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 2b is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 2c is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 2d is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 2e is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 3 is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application;

Figure 4 is a flow chart of an obstruction detection method of a drug infusion device provided in Embodiment 2 of the present application;

Figure 5 is a schematic structural diagram of a congestion detection system provided in Embodiment 3 of the present application.

Detailed ways

In order to enable those in the technical field to better understand the solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only These are part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative efforts should fall within the scope of protection of this application.

It should be noted that the terms "first", "second", etc. in the description and claims of this application and the above-mentioned drawings are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It is to be understood that the data so used are interchangeable under appropriate circumstances so that the embodiments of the application described herein can be practiced in sequences other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, e.g., a process, method, system, product, or apparatus that encompasses a series of steps or units and need not be limited to those explicitly listed. Those steps or elements may instead include other steps or elements not expressly listed or inherent to the process, method, product or apparatus.

Embodiment 1

Figure 1 is a working principle diagram of the infusion process of the drug infusion device provided in Embodiment 1 of the present application. The drug infusion device delivers the drug to the infusion object through the infusion pipeline. The drug infusion process includes two infusion stages. The flow direction of the drug is shown in Figure 1. It should be noted that the drug in this implementation For liquid medicine. In the first infusion phase, the first pump tablet 240 is opened, while the second pump tablet 260 is closed, and the drug flows into the drug infusion device. In the second infusion stage, the first pump tablet 240 is closed, the second pump tablet 260 is opened at the same time, and the pump tablet set 250 is squeezed to pressurize the infusion line. The squeeze pump tablet set 250 includes at least one squeeze pump. The squeezing pump tablet group squeezes the medicine in the infusion line, and the medicine flows out of the medicine infusion device through the second pump piece, and is infused to the infusion object through the motor. When the first pump piece 240 is closed, the liquid cannot flow into the drug infusion device through the infusion line. When the second pump piece 260 is closed, the liquid cannot flow out of the drug infusion device and enter the infusion object.

Figure 2a is a schematic structural diagram of a drug infusion device provided in Embodiment 1 of the present application. The drug infusion device includes: a housing 210, a motor 220, and an infusion pipeline 230. The motor and the motor are sequentially arranged on the path of the infusion pipeline. The first pump tablet 240, the squeeze pump tablet set 250 and the second pump tablet 260 are connected at 220, the detection component 270 is arranged on the infusion pipeline path, and the data processor 280 is connected to the detection component 270. The detection component 270 detects the status parameter of the infusion line 230 and sends the detected status parameter to the data processor 280; the data processor 280 detects the first status parameter according to the first infusion stage detection component 270, and/ Or, the second state parameter detected by the second infusion stage detection component 270 determines whether the infusion line of the drug infusion device is blocked. It should be noted that the structure of the drug infusion device in Figure 2a is only an example, and in particular, the location of the detection component 270 is not limited. Further, the data processor 280 outputs obstruction detection information, and the obstruction detection information output by the data processor 280 at least indicates that the pipeline is blocked. Of course, the output blocking information can further prompt that the pipeline is not blocked so that the user can read it. In some embodiments, the data processor 280 can output identifiers for characterizing "blocking" and "non-blocking", such as 1 and 0, where 1 represents that the infusion line is blocked and 0 represents that the infusion line is not blocked. . Of course, in addition to identification, the output obstruction detection information can also be in one or more combinations of text, graphics, symbols, colors, voices, etc.

The first pump tablet 240, the squeeze pump tablet set 250 and the second pump tablet 260, and the local infusion line 230 are disposed inside the housing 210. Among them, the first pump piece 240, the extrusion pump piece set 250 and the second pump piece 260 are respectively connected to the motor 220.

One end of the motor 220 is connected to the infusion pipeline 230. The infusion pipeline 230 is a pipeline for transporting medicine. The infusion pipeline 230 is connected to an external required storage component. The other end of the motor 220 is connected to another infusion pipeline. , the other infusion pipeline is connected to the body of the infusion subject to realize pumping external drugs into the infusion subject, where the infusion subject may include but is not limited to the human body, animal body, etc. The first pump tablet 240 controls the flow of medication into the medication infusion device. The extrusion pump tablet set 250 can be one extrusion pump tablet or a pump tablet set composed of multiple extrusion pump tablets, and can squeeze and deliver medicine. The second pump tablet 260 controls the flow of medication out of the medication infusion device. The structures of the first pump disc 240, the second pump disc 260, and the extrusion pump discs in the extrusion pump disc set are not limited here. The structures of the above pump discs may be the same or different.

The state parameter of the infusion line 230 may be a state parameter used to characterize the flow process of medicine in the infusion line and used to determine whether there is obstruction in the infusion line. The detection component 270 detects the status of the infusion line 230, including the infusion line in the first infusion stage, the second infusion stage, and the first infusion stage and the second infusion stage in the same cycle. Detect status parameters. Correspondingly, the detected state parameter in the first infusion stage is the first state parameter, and the state parameter detected in the second infusion stage is the second state parameter.

The state parameters detected at different infusion stages are used to characterize the liquid flow status in different pipeline areas of the infusion pipeline 230, where the different pipeline areas of the infusion pipeline 230 may include an upper end pipeline area and a lower end pipeline area relative to the detection component 270, Here the upper pipe area and the lower pipe area are determined based on the direction of liquid flow. By detecting state parameters at different infusion stages, blockage detection in different pipeline areas of the infusion pipeline 230 is achieved. The first infusion phase may be the infusion intermittent phase of the infusion cycle, and the second value phase may be the infusion phase of the infusion cycle.

Based on the above embodiments, the detection component 270 can be installed at different positions on the infusion line path. For example, see FIGS. 2a to 2e , which are respectively schematic structural diagrams of drug infusion states provided by embodiments of the present application, in which the detection components 270 are respectively arranged at different positions on the infusion pipeline. In some embodiments, the detection component 270 may be disposed on the infusion line path between the first pump tablet 240 and the squeeze pump tablet set 250, see Figure 2b. In some embodiments, the detection component 270 is disposed on the infusion line path between the squeeze pump tablet set 250 and the second pump tablet 260, for example, see FIG. 2a. In some embodiments, the detection component 270 is provided on the extrusion pump disc set 250, for example, see FIG. 2c. In some embodiments, the detection component 270 is disposed on the first pump plate 240, for example, see Figure 2d. In some embodiments, the detection component 270 is disposed on the second pump plate, for example, see Figure 2e.

Based on the drug infusion device with any of the above structures, the detection component 270 can detect the first state parameter in the first infusion state and/or the second state parameter in the second infusion state. The detection component sends each monitored status parameter to the data processor 280 .

The data processor 280 receives the status parameters sent by the detection component 270, analyzes and processes the status parameters, and determines the obstruction of the infusion line. Specifically, it may be determined based on the first state parameter in the first infusion phase of one or more cycles whether the upper end of the infusion line of the drug infusion device is blocked; or, it may be determined in the second infusion phase based on one or more cycles. The second state parameter in the infusion phase determines whether obstruction occurs at the lower end of the drug infusion device, or may be based on the first state parameter in the first infusion phase and the second state parameter in the second infusion phase based on one or more cycles. The status parameters jointly determine whether obstruction occurs at the upper and lower ends of the drug infusion device.

The technical solution of this embodiment provides a drug infusion device, detects the status parameters of the infusion pipeline through a detection device installed on the path of the infusion pipeline, and sends the detected status parameters of the infusion pipeline to The data processor performs processing and ultimately determines that the infusion line is blocked. The purpose of diversifying detection methods, reducing costs and simplifying the structure is achieved. When it is detected that the infusion line in the drug infusion device is blocked, a blockage prompt message can be generated to prompt the operator to check the drug infusion device to ensure normal infusion of the drug.

In the above embodiment, different types of detection components can be used to detect the status parameters of the infusion line 230. Correspondingly, different types of status parameters can be detected. Specifically, any type of detection components can be used in the first input A first state parameter of the corresponding type is detected during the injection phase, and/or a second state parameter of the corresponding type is detected during the second infusion phase. In this embodiment, one or more types of status parameters can be used to determine whether the infusion pipeline of the drug infusion device is blocked. Here, different types of status parameters can correspond to different determination rules. Correspondingly, data processing Determination rules corresponding to the detection component types are stored in the device 280 to determine whether the infusion line is blocked.

Optionally, the detection component 270 may be one or more of a pressure detection component, a distance detection component, a deformation detection component, and a liquid flow detection component. In some embodiments, two or more detection components are provided in the drug infusion state. Multiple types of status parameters can be used to determine whether the infusion pipeline is blocked. Different types of status parameters can determine whether the infusion pipeline is blocked. The judgment results are verified against each other to improve the accuracy of the judgment results.

Wherein, the pressure detection component is configured to detect the pressure borne by the infusion pipeline, and the pressure detection component can be a device such as a pressure sensor that detects pressure. When the medicine flows through the infusion line, the medicine generates pressure on the infusion line 230. Correspondingly, when there is obstruction in the infusion line 230, the pressure on the infusion line 230 is also different. For example, in the first infusion stage, if there is a blockage in the upper pipeline area, the medicine cannot flow into the infusion pipeline 230, resulting in a small pressure on the infusion pipeline 230; in the second infusion stage, the lower pipeline area In the case of obstruction, the medicine cannot flow out of the infusion line 230 and the pressure generated on the infusion line 230 is large.

The pressure detection component detects the pressure of the drug on the infusion line 230. Correspondingly, the first state parameter is the first pressure value, and the second state parameter is the second pressure value.

The distance detection component is configured to detect the displacement of the medicine inside the infusion pipeline. The distance detection component can be a distance sensor, an ultrasonic sensor, or other distance detection device. During the process of the drug flowing through the infusion line 230, the displacement of the drug inside the infusion line 230 is detected. The displacement here can be a vertical displacement along the direction of liquid flow. Correspondingly, there is In the case of obstruction, the displacement of the drug in the infusion line 230 is also different. For example, in the first infusion stage, if there is a blockage in the upper end pipeline area, the medicine cannot flow into the infusion pipeline 230, and there is less medicine in the infusion pipeline 230, resulting in a reduction in the displacement of the medicine in the infusion pipeline 230; In the second infusion stage, when the lower end of the pipeline area is blocked, the medicine cannot flow out of the infusion pipeline 230, and there is too much medicine in the infusion pipeline 230, resulting in a large displacement of the medicine in the infusion pipeline 230.

When the distance detection component is installed on the infusion pipeline and the displacement of the medicine inside the infusion pipeline is measured on the surface of the infusion pipeline, correspondingly, the first state parameter is the first displacement value, and the second state parameter is the second displacement. value.

The deformation detection component is configured to detect whether the infusion pipeline is deformed. The deformation detection component may be a deformation sensor or other device that detects deformation. During the process of the drug flowing through the infusion line 230, the drug changes the state of the infusion line 230. Correspondingly, when there is an obstruction on the infusion line 230, the drug deforms the infusion line 230. Also different. The deformation here includes the infusion line 230 being concave and convex. For example, in the first infusion stage, if there is a blockage in the upper end pipeline area, the medicine cannot flow into the infusion pipeline 230, and there is less medicine in the infusion pipeline 230, causing the infusion pipeline 230 to produce concave deformation; in the second During the infusion phase, when the lower end of the pipeline area is blocked, the medicine cannot flow out of the infusion pipeline 230, and there is too much medicine in the infusion pipeline 230, causing the infusion pipeline 230 to undergo convex deformation. The deformation detection component detects the first deformation value and the second deformation value respectively at different infusion stages. It should be noted that the deformation value can be positive or negative. For example, positive deformation represents a convex deformation value, and negative deformation represents a concave deformation value. .

The liquid flow detection component is configured to detect the liquid flow state of the infusion line. The liquid flow detection component can be a device such as a liquid flow sensor that detects the liquid flow state. When the medicine flows through the infusion line 230, the liquid flow state of the infusion line 230 is detected by the liquid flow detection component. The liquid flow state may include whether the liquid is flowing, or the liquid flow state may include the flow speed. When the state of the infusion line changes, the liquid flow state of the infusion line also changes accordingly. For example, when there is obstruction in the infusion line 230, the liquid does not flow, or the liquid flow rate is small. When there is no obstruction, In this case, the liquid flow velocity is large.

Correspondingly, the first state parameter may be the first flow speed, and the second state parameter may be the second flow speed.

On the basis of the above embodiments, the data processor 280 is configured to determine the infusion line obstruction based on one or more detected first status parameters and/or second status parameters. The first state parameter and the second state parameter here may be state parameters detected based on any of the above detection components 270 . For example, taking the detection component 270 as a pressure detection component, the values of the first state parameter and the second state parameter are pressure values detected by the pressure detection component; for example, taking the detection component 270 as a distance detection component, For example, the values of the first state parameter and the second state parameter are distance values detected by the distance detection component; for example, taking the detection component 270 as a deformation detection component, the values of the first state parameter and the second state parameter is the direction and specific amount of deformation detected by the deformation detection component; for example, taking the detection component 270 as a liquid flow detection component, the values of the first state parameter and the second state parameter are detected by the liquid flow detection component. Obtained flow velocity value.

The detection component 270 can detect the status parameters of the infusion line 230 in real time and send the detected status parameters to the data processor 280. It can also detect the current cycle or the next period when the detection instruction is received. Status parameters of the infusion line 230 during the cycle. The data processor 280 can determine whether the infusion line is blocked based on the detection status parameters of one cycle or multiple cycles. For example, the data processor 280 can process the status parameters obtained from multiple detection cycles to determine whether the infusion line is blocked. It can also process each time. The status parameters obtained in one cycle are used to determine whether the infusion pipeline is blocked; the number of processing and detection cycles can also be preset, and the status parameters obtained corresponding to the set cycle number are used to determine whether the infusion pipeline is blocked. block.

In some embodiments, the data processor 280 determines that the infusion line is blocked according to the detected first status parameter and/or the second status parameter and the corresponding preset threshold. For example, it is determined that the infusion line is blocked based on the first state parameter and the first threshold; or, it is determined that the infusion line is blocked based on the second state parameter and the second threshold; or, it is determined based on the first state parameter, the second state parameter, and the third threshold. Three thresholds determine infusion line obstruction.

Determining that the infusion line is blocked based on the first state parameter and the first threshold includes comparing the first state parameter with the first threshold, and determining if the first state parameter meets the first threshold comparison condition. The upper end pipeline area is not blocked. If the first state parameter does not meet the comparison condition of the first threshold, it is determined that the upper end pipeline area of the drug infusion device is blocked. The first thresholds corresponding to different types of state parameters are different, and/or the corresponding first threshold comparison conditions are different. Taking the state parameter as the pressure value as an example, when the first pressure value is greater than the first pressure threshold, it is determined that the first threshold comparison condition is met, that is, the upper end pipeline area of the drug infusion device is not blocked, and at the first pressure value If the pressure is less than the first pressure threshold, it is determined that the first threshold comparison condition is not met, that is, the upper end pipeline area of the drug infusion device is blocked. Taking the status parameter as a displacement value as an example, when the first displacement value is greater than the first displacement threshold, it is determined that the first threshold comparison condition is met, that is, the upper end pipeline area of the drug infusion device is not blocked, and at the first displacement value If it is less than the first displacement threshold, it is determined that the first threshold comparison condition is not met, that is, the upper end pipeline area of the drug infusion device is blocked. Taking the state parameter as the liquid flow state as an example, when the first flow speed is greater than the first flow speed threshold, it is determined that the first threshold comparison condition is met, that is, the upper end pipeline area of the drug infusion device is not blocked, and in the first If the flow velocity value is less than the first flow velocity threshold, it is determined that the first threshold comparison condition is not met, that is, the upper end pipeline area of the drug infusion device is blocked. Taking the state parameter as deformation as an example, when the first deformation value is positive deformation and the first deformation value is greater than the first deformation threshold, it is determined that the first threshold comparison condition is met, that is, the upper end pipeline area of the drug infusion device No obstruction. If the first deformation value is less than the first deformation threshold, it is determined that the first threshold comparison condition is not met, that is, the upper end pipeline area of the drug infusion device is blocked.

Determining that the infusion line is blocked based on the second state parameter and the second threshold includes comparing the second state parameter with the second threshold, and determining if the second state parameter meets the second threshold comparison condition. The lower end pipeline area is not blocked, and when the second state parameter does not meet the comparison condition of the second threshold, it is determined that the lower end pipeline area of the drug infusion device is blocked. Wherein, different types of state parameters correspond to different second thresholds, and/or the corresponding second threshold comparison conditions are different. Taking the state parameter as the pressure value as an example, when the second pressure value is greater than the second pressure threshold, it is determined that the second threshold comparison condition is not met, that is, the lower end pipeline area of the drug infusion device is blocked. If it is less than the second pressure threshold, it is determined that the second threshold comparison condition is met, that is, the lower end pipeline area of the drug infusion device is not blocked. Taking the state parameter as a displacement value as an example, when the second displacement value is greater than the second displacement threshold, it is determined that the second threshold comparison condition is not met, that is, the lower end pipeline area of the drug infusion device is blocked. If it is less than the second displacement threshold, it is determined that the second threshold comparison condition is met, that is, the lower end pipeline area of the drug infusion device is not blocked. Taking the state parameter as the liquid flow state as an example, when the second flow speed is greater than the second flow speed threshold, it is determined that the second threshold comparison condition is met, that is, the lower end pipeline area of the drug infusion device is not blocked, and in the second If the flow velocity value is less than the second flow velocity threshold, it is determined that the second threshold comparison condition is not met, that is, the lower end pipeline area of the drug infusion device is blocked. Taking the state parameter as deformation as an example, when the second deformation value is positive deformation and the second deformation value is greater than the second deformation threshold, it is determined that the second threshold comparison condition is not met, that is, the lower end pipeline of the drug infusion device If the region is blocked, when the second deformation value is negative deformation and is less than the second deformation threshold, it is determined that the second threshold comparison condition is met, that is, the lower end pipeline region of the drug infusion device is not blocked.

Determining that the infusion line is blocked based on the first state parameter, the second state parameter and the third threshold includes: comparing the parameter sum of the first state parameter and the second state parameter with the third threshold, and determining the infusion according to the comparison result. Whether the pipeline is blocked. Taking the status parameter as the pressure value as an example, when the pressure sum of the first pressure value and the second pressure value is greater than the third pressure threshold, it is determined that the pipeline area at the lower end of the infusion pipeline is blocked. If the pressure sum of the two pressure values is less than the third pressure threshold, it is determined that the upper pipeline area of the infusion pipeline is blocked. Taking the state parameter as the deformation value as an example, when the deformation sum of the first deformation value and the second deformation value is greater than the third deformation threshold, it is determined that the pipeline area at the lower end of the infusion pipeline is blocked. If the deformation sum of the two deformation values is less than the third deformation threshold, it is determined that the upper pipeline area on the infusion pipeline is blocked. Taking the state parameter as the displacement value as an example, when the displacement sum of the first displacement value and the second displacement value is greater than the third displacement threshold, it is determined that the pipeline area at the lower end of the infusion pipeline is blocked. If the displacement sum of the two displacement values is less than the third displacement threshold, it is determined that the upper pipeline area on the infusion pipeline is blocked. Taking the state parameter as the liquid flow state as an example, when the sum of the first flow speed and the second flow speed is greater than the third speed threshold, it is determined that there is no obstruction on the infusion pipeline. When the sum of the speeds is less than the third speed threshold, it is determined that there is an obstruction on the infusion line.

In some embodiments, the data processor 280 may determine that the infusion line is blocked based on multiple detected changes in the first state parameter and/or changes in the second state parameter. Specifically, the data processor 280 may determine a parameter change based on the first state parameter and/or the second state parameter detected multiple times, and determine that the infusion line of the drug infusion device 230 is blocked based on the parameter change.

The data processor 280 may determine that the infusion line 230 is blocked based on changes in detected status parameters over multiple cycles. For example, the difference between the current state parameter and the corresponding state parameter in other cycles can be expressed as a change in the state parameter. Correspondingly, the change in the state parameter can include the state parameter in the current cycle and the state parameters in multiple other cycles. respectively, where the number of other periods is at least one. The change of the state parameter can also be expressed by the change of the difference between two adjacent times, or it can also be expressed by the slope of the change of the state parameter. Specifically, the judgment can be made by comparing changes in state parameters with preset thresholds. Changes in state parameters include changes in the first state parameter, changes in the second state parameter, and at least one of parameters and changes in the first state parameter and the second state parameter. The above-mentioned first state parameter and second state parameter may be any parameter type among pressure value, deformation value, displacement value and liquid flow state.

When the change of the first state parameter does not meet the parameter change condition, it is determined that the upper end pipeline area of the infusion pipeline is blocked. Specifically, when each difference in the change of the first state parameter is greater than the first difference threshold, it is determined that the upper end pipeline area of the infusion management is blocked. When the change of the second state parameter does not meet the parameter change conditions, it is determined that the upper end pipeline area of the infusion management is blocked. Specifically, each difference in the change of the second state parameter is greater than the second difference threshold. In this case, it is determined that the lower end pipeline area of the infusion management is blocked. Among the parameters and changes of the first state parameter and the second state parameter, if each parameter and difference value are greater than the third difference threshold, it is determined that the lower end pipeline area of the infusion management is blocked. If the value is less than the fourth difference threshold, it is determined that the upper end pipeline area of the infusion management is clogged.

In this embodiment, the data processor 280 is further configured to perform verification based on multiple detections of obstruction, and determine that the infusion line of the drug infusion device is blocked when the continuous verification conditions are met. The number of verifications can be preset, for example, 3 times. The continuous verification conditions can be preset to the number of consecutive verifications. If the infusion line is blocked, it is determined that the infusion line is blocked. When the continuous verification conditions are met, it is determined that the infusion line is blocked. When the continuous verification conditions are met, it is determined that the infusion line is not blocked. Obstruction of the infusion line may be caused by external factors such as manual compression or misoperation. After eliminating external interference, confirm again.

The technical solution provided by the embodiments of this application avoids accidental misdetection by continuously verifying the verification results, thereby improving the accuracy of infusion line obstruction determination.

Based on the above embodiments, Embodiment 1 of the present application also provides an example of a drug infusion device, and a portable infusion pump is selected as the drug infusion device. It includes a casing, a motor, an outlet valve pump piece (i.e., the second pump piece), a squeeze pump piece, a pressure sensor, and an inlet valve pump piece (i.e., the first pump piece). The drug infusion device may include a data processor (Figure 3 (not shown in, connected to the pressure sensor). As shown in Figure 3.

The portable infusion pump contains 3 pump pieces, which are spaced apart at a certain distance, and the pressure sensor can be located in the gap between any two pump pieces.

Since the portable infusion pump is in intermittent infusion mode, during the infusion interval, the pressure sensor can detect the upper occlusion pressure, which is the first state parameter; during the infusion process, the pressure sensor can detect the lower occlusion pressure, which is the second state parameter.

The data processor performs obstruction determination based on the upper obstruction pressure and/or lower obstruction pressure collected by the pressure sensor. The determination method 1 of the upper and lower obstruction pressure is: an analog-to-digital converter is provided in the pressure sensor to convert the collected analog pressure value into Digital pressure value, that is, AD value. When measuring the upper obstruction pressure, compare the AD value read in real time with the upper obstruction pressure AD threshold set in the register. If it is lower than the AD threshold, it is determined to be upper obstruction; when measuring the lower obstruction pressure The AD value read in real time is compared with the lower obstruction pressure AD value set in the register. If it is higher than the AD threshold, it is determined to be lower obstruction.

The method 2 for determining the upper and lower obstruction pressure is: the pressure sensor converts the pressure value into an AD value, and when measuring the upper obstruction pressure, the AD value read in real time is stored in the register, and this value is compared with the AD read within the set number of times. When the difference is greater than a set value, it is determined to be an upper blockage. The AD value before exceeding the set number of times can be deleted in the register; when measuring the lower blockage pressure, the AD value read in real time is stored in the register. , compare this value with the AD value read within the set number of times. When the difference is greater than a set value, it is determined to be blocked. The AD value before exceeding the set number of times can be deleted in the register.

Method 3 for determining the upper and lower obstruction pressure is: the pressure sensor converts the pressure value into an AD value, and sums the upper and lower obstruction pressure AD values read in the same infusion cycle. When the sum is greater than the threshold set in the register, That is, it is considered to be lower blocked; when its sum value is less than the threshold set in the register, it is considered to be upper blocked (considering a single fault).

The determination method 4 of the upper and lower obstruction pressure is: the pressure sensor converts the pressure value into an AD value, sums the upper and lower obstruction pressure AD values read in the same infusion cycle, and compares the AD values read within a set number of times. , when the difference is greater than a set value, it is determined to be lower blocking. When the difference is less than a set value, it is determined to be upper blocking. The AD value before exceeding the set number can be deleted in the register.

Embodiment 2

Figure 4 is a flow chart of a method for detecting obstruction of a drug infusion device provided in Embodiment 2 of the present application. This method is applied to a data processor in the drug infusion device. The drug infusion device may include a housing, a motor, and an infusion pipeline. A first pump tablet, a squeeze pump tablet set, and a second pump tablet are sequentially provided on the path of the infusion pipeline and connected to the motor. A detection component on the pipeline path, and a data processor connected to the detection component.

The method includes:

S410. Obtain the status parameters of the infusion pipeline detected by the detection component.

The status parameters of the infusion line are measured by the detection component, and the data processor obtains the status parameters of the infusion line detected by the detection component.

S420. Determine that the infusion line is blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage.

Optionally, determining that the infusion line is blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage, includes: : Determine that the infusion line is blocked based on the first status parameter and/or the second status parameter detected one or more times.

Optionally, determining that the infusion line is blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage, includes: : Determine that the infusion line is blocked according to the detected first state parameter and/or second state parameter and the corresponding preset threshold.

Optionally, determining that the infusion line is blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage, includes: : Determine that the infusion line is blocked based on multiple detected changes in the first state parameter and/or changes in the second state parameter.

Optionally, the method also includes: performing verification based on multiple detections of obstruction, and determining that the infusion line is blocked if the continuous verification conditions are met.

The technical solution of this embodiment is to apply the method of detecting obstruction of the drug infusion device to the drug infusion device, obtain the status parameters of the infusion pipeline, and determine the obstruction of the infusion pipeline based on the status parameters of the infusion pipeline.

In addition, the specific settings and implementation of the drug infusion device can be the solutions in other embodiments, and the implementation of the specific steps in the method of detecting obstruction of the drug infusion device can also be the solutions in other embodiments, which will not be described again.

Embodiment 3

Figure 5 is a blockage detection system provided in Embodiment 3 of the present application. The drug infusion device in the obstruction detection system 10 includes at least one processor 11, and a memory communicatively connected to the at least one processor 11, such as a read-only memory (ROM) 12, a random access memory (RAM) 13, etc., and the drug infusion device The specific settings and implementation of the device may be those in other embodiments, and will not be described again. Among them, the memory stores a computer program that can be executed by at least one processor. The processor 11 can be based on the computer program stored in the read-only memory (ROM) 12 or loaded from the storage unit 18 into the random access memory (RAM) 13. Computer programs to perform various appropriate actions and processes. In the RAM 13, various programs and data required for the operation of the obstruction detection system 10 can also be stored. The processor 11, the ROM 12 and the RAM 13 are connected to each other via the bus 14. An input/output (I/O) interface 15 is also connected to bus 14 .

Multiple components in the obstruction detection system 10 are connected to the I/O interface 15, including: an input unit 16, such as a keyboard, a mouse, etc.; an output unit 17, such as various types of displays, speakers, etc.; a storage unit 18, such as a disk, Optical disc, etc.; and communication unit 19, such as network card, modem, wireless communication transceiver, etc. The communication unit 19 allows the congestion detection system 10 to exchange information/data with other devices via computer networks such as the Internet and/or various telecommunications networks.

Processor 11 may be a variety of general and/or special purpose processing components having processing and computing capabilities. Some examples of the processor 11 include, but are not limited to, a central processing unit (CPU), a graphics processing unit (GPU), various dedicated artificial intelligence (AI) computing chips, various processors running machine learning model algorithms, digital signal processing processor (DSP), and any appropriate processor, controller, microcontroller, etc. The processor 11 performs various methods and processes described above, such as an obstruction detection method of a drug infusion device. The specific steps in the method of blocking detection can also be implemented by solutions in other embodiments, and will not be described again.

In some embodiments, an obstruction detection method of a drug infusion device may be implemented as a computer program, which is tangibly embodied in a computer-readable storage medium, such as the storage unit 18 . In some embodiments, part or all of the computer program may be loaded and/or installed onto the obstruction detection system 10 via the ROM 12 and/or the communication unit 19. When the computer program is loaded into the RAM 13 and executed by the processor 11, one or more steps of the obstruction detection method of a drug infusion device described above may be performed. Alternatively, in other embodiments, the processor 11 may be configured to perform an obstruction detection method of a drug infusion device in any other suitable manner (eg, by means of firmware).

Various implementations of the systems and techniques described above may be implemented in digital electronic circuit systems, integrated circuit systems, field programmable gate arrays (FPGAs), application specific integrated circuits (ASICs), application specific standard products (ASSPs), systems on a chip implemented in a system (SOC), load programmable logic device (CPLD), computer hardware, firmware, software, and/or a combination thereof. These various embodiments may include implementation in one or more computer programs executable and/or interpreted on a programmable system including at least one programmable processor, the programmable processor The processor, which may be a special purpose or general purpose programmable processor, may receive data and instructions from a storage system, at least one input device, and at least one output device, and transmit data and instructions to the storage system, the at least one input device, and the at least one output device. An output device.

A computer program for implementing an obstruction detection method of a drug infusion device of the present application can be written using any combination of one or more programming languages. These computer programs may be provided to a processor of a general-purpose computer, a special-purpose computer, or other programmable data processing device, such that the computer program, when executed by the processor, causes the functions/operations specified in the flowcharts and/or block diagrams to be implemented. A computer program may execute entirely on the machine, partly on the machine, as a stand-alone software package, partly on the machine and partly on a remote machine or entirely on the remote machine or server.

Embodiment 4

Embodiment 4 of the present application also provides a computer-readable storage medium. The computer-readable storage medium stores computer instructions. The computer instructions are used to cause the processor to execute an obstruction detection method of a drug infusion device. The method includes:

Obtain the status parameters of the infusion line detected by the detection component;

In the context of this application, a computer-readable storage medium may be a tangible medium that may contain or store a computer program for use by or in connection with an instruction execution system, apparatus, or device. Computer-readable storage media may include, but are not limited to, electronic, magnetic, optical, electromagnetic, infrared, or semiconductor systems, devices or devices, or any suitable combination of the foregoing. Alternatively, the computer-readable storage medium may be a machine-readable signal medium. More specific examples of machine-readable storage media would include one or more wire-based electrical connections, laptop disks, hard drives, random access memory (RAM), read only memory (ROM), erasable programmable read only memory (EPROM or flash memory), optical fiber, portable compact disk read-only memory (CD-ROM), optical storage device, magnetic storage device, or any suitable combination of the above.

To provide interaction with a user, the systems and techniques described herein may be implemented on an electronic device having a display device (eg, a CRT (Cathode Ray Tube) or LCD (Liquid Crystal Display)) configured to display information to a user monitor); and a keyboard and pointing device (e.g., a mouse or a trackball) through which a user can provide input to the electronic device. Other kinds of devices may also be configured to provide interaction with the user; for example, the feedback provided to the user may be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and may be provided in any form, including Acoustic input, voice input or tactile input) to receive input from the user.

The systems and techniques described herein may be implemented in a computing system that includes back-end components (e.g., as a data server), or a computing system that includes middleware components (e.g., an application server), or a computing system that includes front-end components (e.g., A user's computer having a graphical user interface or web browser through which the user can interact with implementations of the systems and technologies described herein), or including such backend components, middleware components, or any combination of front-end components in a computing system. The components of the system may be interconnected by any form or medium of digital data communication (eg, a communications network). Examples of communication networks include: local area network (LAN), wide area network (WAN), blockchain network, and the Internet.

Computing systems may include clients and servers. Clients and servers are generally remote from each other and typically interact over a communications network. The relationship of client and server is created by computer programs running on corresponding computers and having a client-server relationship with each other. The server can be a cloud server, also known as cloud computing server or cloud host. It is a host product in the cloud computing service system to solve the problems of difficult management and weak business scalability in traditional physical hosts and VPS services. defect.

It should be understood that various forms of the process shown above may be used, with steps reordered, added or deleted. For example, each step described in this application can be executed in parallel, sequentially, or in a different order. As long as the desired results of the technical solution of this application can be achieved, there is no limitation here.

Claims

A drug infusion device, including: a housing, a motor, an infusion pipeline, and a first pump tablet, a squeeze pump tablet group and a second pump tablet that are sequentially arranged on the path of the infusion pipeline and connected to the motor, A detection component provided on the infusion line path, and a data processor connected to the detection component;

The detection component detects the status parameter of the infusion line and sends the detected status parameter to the data processor;

The data processor determines the infusion line based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage. block.
The drug infusion device according to claim 1, wherein the detection component is provided on the infusion pipeline path between the first pump tablet and the squeeze pump tablet set;

Alternatively, the detection component is disposed on the infusion pipeline path between the squeeze pump tablet set and the second pump tablet;

Alternatively, the detection component is provided on the first pump piece, the second pump piece, or the extrusion pump piece set.
The drug infusion device according to any one of claims 1-2, wherein the detection component includes one or more of the following: a pressure detection component, a distance detection component, a deformation detection component, and a liquid flow detection component;

Wherein, the pressure detection component detects the pressure of the infusion line;

The distance detection component detects the displacement of the surface of the infusion line;

The deformation detection component detects the deformation of the infusion line;

The liquid flow detection component detects the liquid flow status of the infusion line.
The drug infusion device according to claim 1, wherein the data processor is configured to:

The infusion line obstruction is determined based on one or more detected first status parameters and/or second status parameters.
The drug infusion device according to claim 4, wherein the data processor is configured to:

The infusion line is determined to be blocked according to the detected first state parameter and/or second state parameter and the corresponding preset threshold.
The drug infusion device according to claim 4, wherein the data processor is configured to:

The infusion line is determined to be blocked based on multiple detected changes in the first state parameter and/or changes in the second state parameter.
The drug infusion device according to claim 5 or 6, wherein the data processor is further configured to:

Verification is performed based on multiple detections of obstruction, and when continuous verification conditions are met, it is determined that the infusion line is blocked.
A method for detecting obstruction of a drug infusion device, applied to a data processor in a drug infusion device. The drug infusion device includes a housing, a motor, an infusion pipeline, and is sequentially arranged on the path of the infusion pipeline and The first pump piece, the squeeze pump piece group and the second pump piece connected to the motor, a detection component provided on the infusion pipeline path, and a data processor connected to the detection component;

The methods include:

Obtain the status parameters of the infusion line detected by the detection component;

The infusion line is determined to be blocked based on the first state parameter detected by the detection component in the first infusion stage, and/or the second state parameter detected by the detection component in the second infusion stage.
A blockage detection system including:

drug infusion devices;

The drug infusion device includes at least one processor; and

a memory communicatively connected to the at least one processor; wherein,

The memory stores a computer program executable by the at least one processor, the computer program being executed by the at least one processor, so that the at least one processor can perform the drug infusion of claim 8 Device obstruction detection method.
A computer-readable storage medium stores computer instructions, and the computer instructions are used to implement the obstruction detection method of the drug infusion device of claim 8 when executed by a processor.