WO2023284052A1

WO2023284052A1 - Device for removing clot in blood vessel and system thereof

Info

Publication number: WO2023284052A1
Application number: PCT/CN2021/112440
Authority: WO
Inventors: 李培尚; 吴巍巍; 李静
Original assignee: 江苏迈得诺医疗集团有限公司
Priority date: 2021-07-13
Filing date: 2021-08-13
Publication date: 2023-01-19
Also published as: CN113331919A; CN113331919B

Abstract

A device for removing a clot in a blood vessel and a system thereof, which relate the the field of medical instruments, the device comprising a removing mechanism and a power component; the removing mechanism comprises a core wire (1), and an arched member (2), the arched member (2) having a closed state and an arched state, and one end of the arched member (2) being connected to the core wire (1) at a set position; the power component comprises a first driving unit (3) and a second driving unit, the first driving unit (3) being connected to the core wire (1) and driving the core wire (1) to rotate, and when the arched member (2) is in the arched state, the core wire (1) driving the arched member (2) to break up a clot; the second driving unit is connected to one end of the arched member (2) distant from the set position, and the second driving unit enables the arched member (2) to switch from the closed state to the arched state; and the second driving unit is slidably connected to the first driving unit (3). The arched member (2) can break up and remove clots over a large area at lesions, and removal efficiency is high. Moreover, with regard to plaque attached to a vessel wall, the arched member (2) can directly move close to the vessel wall to remove the plaque, without being blocked by any object.

Description

A device and system for removing blood vessel agglomerates

technical field

The present application relates to the field of medical devices, in particular to a device and system for removing blood vessel agglomerates.

Background technique

Vascular agglomerates such as thrombus, plaque, etc., when deposited or attached to the inner wall of the blood vessel, will limit the size of the lumen and reduce the flow of blood, which may lead to insufficient blood supply, seriously damage tissue function, and may even lead to death.

In the prior art, such as Chinese patent document CN109199527A discloses a mechanical thrombus removal device, the thrombus removal head involved is a hollow member with a proximal end and a distal end, and the proximal end of the thrombus removal head includes at least one thrombus removal side hole , preferably, the proximal end of the plug removal head is in the form of a circular ring; the distal end of the plug removal head is a conical curved surface structure with at least one oblique hole and a top hole.

In the above-mentioned patent documents, the thrombus removal side hole is used as the path for the thrombus to enter the thrombus removal head. The thrombus breaking knife is located in the inner cavity of the thrombus removal head. The thrombus must enter the thrombus removal side hole before it can be broken by the thrombus breaking knife. The thrombus breaking knife cannot be used with The thrombus is fully contacted, and the efficiency of thrombus fragmentation is limited.

Contents of the invention

This application provides a device and system for removing blood vessel agglomerates to solve the thrombus removal device in the prior art. The thrombus must enter the side hole for thrombus removal before it can be broken by the thrombus breaking knife. The thrombus breaking knife cannot fully contact the thrombus. The problem of limited throttling efficiency.

The technical scheme of the application is:

According to one aspect of the present application, there is provided a device for removing vascular agglomerates, including a removal mechanism and a power assembly. The removal mechanism includes a core wire and an arching member. The arching member has a retracted state and an arched state, and one end thereof is connected to the The core wire is connected to a set position; the power assembly includes a first drive unit and a second drive unit, the first drive unit is connected to the core wire and drives the core wire to rotate, and the arching member is In the arched state, the core wire drives the arched part to break the agglomerates;

The second drive unit is connected to an end of the arched member away from the set position, and the second drive unit is adapted to move toward the set position under the action of an external force, so that the arched member The folded state is transformed into the arched state; the second driving unit is slidingly connected with the first driving unit.

Preferably, the clearing mechanism further includes a sleeve, the sleeve is sleeved on the core wire, one end of which is connected to the arching member, and the other end is adapted to move toward the set position under the action of the second driving unit. position action.

Preferably, the second drive unit includes a connection sleeve, one end of which is close to the set position is connected to the bushing, and the other end is slidably connected to the first drive unit.

Preferably, the device for removing blood vessel agglomerates further includes a handle, and the first driving unit is connected to the handle.

Preferably, the handle is provided with a snap-fit structure, and the connecting sleeve is connected with the snap-fit structure after being moved by an external force.

Preferably, the device for removing blood vessel agglomerates further includes a suction tube, which is sleeved on the outside of the cannula, and forms a set gap with the outer wall of the cannula for absorbing broken agglomerates or injection solution .

Preferably, the device for removing blood vessel agglomerates further includes a communication piece, the communication piece is connected to the suction tube, and is suitable for the extracting device to extract broken agglomerates through the set gap.

Preferably, the connecting member includes a first interface and a second interface that communicate with each other; the suction tube is slidably connected to the first interface, and the second interface is suitable for connecting with the extraction device.

Preferably, the connecting member further includes a third interface, the core wire passes through the third interface and is connected to the first drive unit, and the sleeve passes through the third interface and connects to the second Drive unit connection.

Preferably, the device for removing blood vessel agglomerates further includes a seal, and the seal is arranged at the third interface to close the space between the third interface and the cannula.

Preferably, the second driving member includes a sliding sleeve connected to the connecting member, the sliding sleeve is provided with an installation groove, the sealing member is arranged in the installation groove, and is connected to the third interface. Face to face.

Preferably, a part of the communicating member is connected to the suction tube, and another part is connected to the second driving unit, so as to maintain the relative position between the suction tube and the arching member.

Preferably, the suction tube includes a sliding part that is slidably connected to the connecting piece; the suction tube has a clearing state and a protection state; when the suction tube is in the protection state, the sliding part moves toward the set position And cover the arched part; when the suction tube is in the clearing state, the sliding part moves away from the set position to expose the arched part.

According to an aspect of the present application, there is provided a system with a blood vessel agglomeration removal device, including the above-mentioned blood vessel agglomeration removal device, and also includes an extraction device, which is connected to the suction tube away from the arch one end of the connection.

The technical scheme of the present application has the following advantages:

1. The device for removing vascular agglomerates of the present application includes a removal mechanism and a power assembly. The removal mechanism includes a core wire and an arching member. The arching member has a retracted state and an arched state, and one end thereof is connected to the core wire at a set position The power assembly includes a first drive unit and a second drive unit. The first drive unit is connected to the core wire and drives the core wire to rotate. When the arching part is in the arched state, the core wire drives the arching part to break the agglomerates ; The second drive unit is connected to the end of the arched member away from the set position, and the second drive unit is slidably connected to the first drive unit.

During the initial use, the arched part is in a retracted state, so that the size of the entire clearing mechanism is small so as to reach the lesion area. After reaching the lesion area, an external force acts on the second drive unit, causing the second drive unit to slide relative to the first drive unit , the arching part moves toward the set position under the action of the second driving unit, so that the arching part changes from the retracted state to the arched state; then, the core wire rotates around its own central axis driven by the first driving unit, and drives The arching part in the arched state moves, and the arching part is driven by the core wire to break the agglomerates. In the arched state, the arched part is in full contact with the agglomerate, and the arched part can break and remove the agglomerate in the lesion in a large area, without the need for the agglomerate to enter the side hole of the thrombectomy for operation and removal. Efficiency should be high. And for the plaque attached to the blood vessel wall, the arched part can be directly close to the blood vessel wall to remove the plaque without being blocked by any object.

Moreover, since the first drive unit is slidably connected to the second drive unit, the focus of the second drive unit is the first drive unit, so when in use, the operator can just hold the first drive unit without additional personnel Assisted operation frees the operator's hands and facilitates surgical operation.

2. In the device for removing blood vessel agglomerates of the present application, one end of the connecting sleeve close to the set position is connected to the cannula, and the other end is slidably connected to the first driving unit. On the one hand, the connecting sleeve connects the bushing, so that external force can act on the connecting sleeve and make it move toward the set position; on the other hand, the connecting sleeve plays an auxiliary role in installation. Because the connection sleeve is slidably connected with the first drive unit, during installation, the driver of the first drive unit slides into the connection sleeve, so the installation is very convenient and quick.

3. The device for removing blood vessel agglomerates of the present application also includes a suction tube, which is placed outside the cannula, and forms a setting between the outer wall of the cannula for absorbing broken agglomerates or injection solution gap.

By setting the suction tube, while the removal mechanism crushes the blood vessel agglomerate, the broken agglomerate is sucked through the suction tube, so that crushing and suction can be completed by one device, and the operation is convenient and efficient.

Description of drawings

In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the following will briefly introduce the accompanying drawings that need to be used in the description of the specific embodiments or prior art. Obviously, the accompanying drawings in the following description The drawings are some implementations of the present application, and those skilled in the art can obtain other drawings based on these drawings without creative work.

Fig. 1 is the schematic diagram of the device for removing blood vessel agglomerate of the present application;

Fig. 2 is a partial schematic diagram of the top view shown in Fig. 1;

Fig. 3 is a schematic diagram of the structure shown in Fig. 1 after removing the handle;

Fig. 4 is a schematic diagram of the enlarged view of part A shown in Fig. 3;

Fig. 5 is a schematic diagram of the enlarged view of part B shown in Fig. 3;

Fig. 6 is a schematic diagram of the enlarged view of part C shown in Fig. 3;

FIG. 7 is a schematic diagram of a system of the present application with a device for removing blood vessel agglomerates.

Explanation of reference signs:

1-core wire; 2-arching part; 3-first driving unit; 4-sleeve; 5-connecting sleeve; 6-hand holding part; 7-installation part; 8-hand holding part; 10-controller; 11-clamping structure; 12-suction tube; 13-communication piece; 14-first interface; 15-second interface; 16-third interface; 17-seal; 18-sliding sleeve; 19 - installation groove; 20 - sliding part; 21 - pushing part; 22 - transmission shaft; 23 - extracting device.

detailed description

The technical solutions of the present application will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are part of the embodiments of the present application, not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of this application.

In the description of this application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, use a specific orientation construction and operation, therefore should not be construed as limiting the application. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.

In the description of this application, it should be noted that unless otherwise specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. Connected, or integrally connected; it can be mechanically connected or electrically connected; it can be directly connected or indirectly connected through an intermediary, and it can be the internal communication of two components. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood in specific situations.

In addition, the technical features involved in the different embodiments of the present application described below may be combined as long as they do not constitute a conflict with each other.

Embodiment one

The device for removing vascular agglomerates in this embodiment, as shown in Figures 1-7, includes a clearing mechanism and a power assembly. The clearing mechanism includes a core wire 1 and an arching member 2, and the arching member 2 has a retracted state and an arched state , one end of which is connected to the core wire 1 at a set position. It should be noted that the "set position" in this embodiment is introduced to clearly describe the technical solution of this embodiment, and is a certain position in a three-dimensional space, which can be set according to actual use requirements.

The power assembly includes a first drive unit 3 and a second drive unit. The first drive unit 3 is connected to the core wire 1 and drives the core wire 1 to rotate. When the arching member 2 is in the arched state, the core wire 1 drives the arching member 2 Crush the agglomerates; the second drive unit is connected to the end of the arched part 2 away from the set position, and the second drive unit is suitable for moving towards the set position under the action of an external force, so that the arched part 2 from the folded state to the arched state; in this embodiment, the first drive unit 3 includes a driver 9 and a controller 10, the driver 9 adopts a micro motor, the output shaft of the micro motor is connected to the core wire 1, and the operator The action of the driving member 9 is controlled by the controller 10 .

During the initial use, the arching member 2 is in a retracted state, so that the size of the entire clearing mechanism is small so as to reach the lesion area. After reaching the lesion area, an external force acts on the second drive unit, causing the second drive unit to generate a force relative to the first drive unit 3 . Relatively sliding, the arching member 2 moves towards the set position under the action of the second driving unit, so that the arching member 2 is converted from the retracted state to the arched state; then, the core wire 1 is driven by the first driving unit 3 to wind around itself The central shaft rotates and drives the arching member 2 in the arched state to move, and the arching member 2 is driven by the core wire 1 to break the agglomerates.

In the arched state, the arched part 2 is in full contact with the agglomerate, and the arched part 2 can break and remove the agglomerated matter in the lesion in a large area, without the need for the agglomerated matter to enter the side hole for thrombectomy. , the removal efficiency should be high. And for the plaque attached to the blood vessel wall, the arched part 2 can be directly close to the blood vessel wall to remove the plaque without being blocked by any object.

Wherein, the clearing mechanism further includes a sleeve 4, which is sleeved on the core wire 1, one end of which is connected to the arching member 2, and the other end is adapted to move toward the set position under the action of the second driving unit.

Wherein, the second drive unit includes a connecting sleeve 5 and a sliding sleeve 18, one end of the connecting sleeve 5 close to the set position is connected to the sleeve 4, and the other end is slidably connected to the drive shaft 22 of the driving member 9 of the first driving unit 3 , the sliding sleeve 18 is set on the outside of the connecting sleeve 5, and is fixedly connected with the connecting sleeve 5, the external force directly acts on the sliding sleeve 18, and the connecting sleeve 5 drives the sleeve 4 to move towards the set position to realize the arching 2 toggles between the two states. Specifically, the external dimensions of the connecting sleeve 5 are adapted to the driving member 9, and the connecting sleeve 5 is connected to the sleeve 4 on the one hand, so that the external force can pass through the sliding sleeve 18 and the connecting sleeve 5 to make the sleeve 4 move toward the set position; On the other hand, the connecting sleeve 5 plays an auxiliary installation role. Since the connecting sleeve 5 is slidingly connected to the transmission shaft 22 of the driving member 9, the driving member 9 of the first driving unit 3 slides into the connecting sleeve 5 during installation, and the installation is very convenient and fast.

The device for removing blood vessel agglomerates also includes a handle 6, which is a pistol-shaped structure, and includes a handle 8 and a mounting portion 7, and the handle 8 is used for the operator to hold to complete the operation. The controller 10 is installed on the handle part 8 for conveniently controlling the action of the driving part 9 , and the driving part 9 is fixedly connected with the installation part 7 . This pistol-shaped construction is easy to use and facilitates efficient and precise operation.

The first drive unit 3 and the second drive unit are slidably connected through the drive member 9 and the connecting sleeve 5. The focus point of the second drive unit is the first drive unit 3, so when in use, the operator can hold the first drive unit by hand. 3. The fixedly connected handle 6 adjusts the relative position between the first drive unit 3 and the second drive unit, and no additional personnel are required to perform auxiliary operations, which frees the operator's hands and facilitates surgical operations. It should be noted that, in this embodiment, "the force point of the second driving unit" refers to the support force that the first driving unit 3 acts on the second driving unit.

Specifically, the sliding sleeve 18 is also provided with a pushing portion 21 , and the hand pushing portion is connected to the engaging structure 11 on the mounting portion 7 , that is, the connecting sleeve 5 is connected to the engaging structure 11 through the pushing portion 21 on the sliding sleeve 18 . Specifically, an external force pushes the pushing portion 21 on the sliding sleeve 18 during use, and when the arching member 2 reaches a predetermined arched state, the pushing portion 21 is connected to the engaging structure 11 on the mounting portion 7 . It should be noted that the locking structure 11 here refers to a concavo-convex structure formed by a plurality of continuous slots, which can adjust the degree of deformation of the arched member 2 by connecting with the slots at different positions.

Embodiment two

The device for removing blood vessel agglomerates in this embodiment, as shown in Figures 1-7, on the basis of Embodiment 1, also includes a suction tube 12 and a connecting piece 13, the suction tube 12 is sleeved on the outside of the sleeve 4, and is connected with A set gap for absorbing broken agglomerates or injection solution is formed between the outer walls of the casing 4. It should be noted that in this embodiment, the set gap is used for absorbing broken agglomerates, but it is not excluded in In some procedures, the solution is injected into the lesion through a set gap.

The connecting piece 13 is connected with the suction pipe 12, and is suitable for the extraction device 23 to extract the broken agglomerates through the set gap. By setting the suction tube 12, while the cleaning mechanism crushes the vascular agglomerates, the broken agglomerates are sucked through the suction tube 12, so that crushing and suction can be completed by one device, and the operation is convenient and efficient. Specifically, part of the communication member 13 is connected to the suction tube 12, and the other part is connected to the second driving unit. After being set up like this, because the second drive unit is connected with the sleeve pipe 4, the sleeve pipe 4 is connected with the arched part 2 again, and the connecting part 13 is connected with the suction tube 12, so after setting in this way, it can be ensured that the suction tube 12 is connected with the arched part 2. relative position between them.

Wherein, the suction tube 12 includes a sliding part 20 that is slidably connected with the connecting piece 13; the suction tube 12 has a clearing state and a protection state; when the suction tube 12 is in the protection state, the sliding part 20 moves toward the set position and covers the arched Part 2; when the suction tube 12 is in the clearing state, the sliding part 20 moves away from the set position to expose the arched part 2.

The sliding part 20 is transitionally fitted with the connecting piece 13 . It should be noted that the transitional fit satisfies that the sliding part 20 and the connecting member 13 are relatively static when there is no external force, and the two can slide relative to each other under the external force. The purpose of this matching method is: on the one hand, the sliding part 20 can be manually pushed to realize the state switching of the suction tube 12, and no additional power source is required. The additional power source refers to the motor, air source power, etc., which will cause The entire mechanism structure is more complicated and the cost is higher; on the other hand, it prevents blood or broken agglomerates from leaking at the part where the sliding part 20 is connected to the connecting piece 13 .

Wherein, the connecting member 13 includes a first interface 14 and a second interface 15 which communicate with each other; the suction tube 12 is slidably connected with the first interface 14, so as to realize the switching between two different states of the suction tube 12, and the second interface 15 is suitable for In connection with the extraction device 23. The connecting member 13 also includes a third interface 16 through which the core wire 1 is connected to the first driving unit 3 , and the sleeve 4 is passed through the third interface 16 and connected to the second driving unit.

Specifically, the device for removing blood vessel agglomerates also includes a sealing member 17, which is arranged at the third interface 16 to close the space between the third interface 16 and the sleeve 4 to prevent the broken agglomerate Or the injection solution flows out through the third interface 16, which affects the use; the side of the sliding sleeve 18 close to the set position is connected with the connecting member 13, the sliding sleeve 18 is provided with an installation groove 19, and the sealing member 17 is arranged in the installation groove 19 , and offset against the end face of the third interface 16, by setting in this way, there is no need to change the structure of the third interface 16, which is convenient for manufacture and disassembly.

Embodiment Three

The system with the device for removing blood vessel agglomerates in this embodiment, as shown in FIG. One end of the arched member 2 is connected.

The extracting device 23 has functions of negative pressure suction and blood filtration, and its specific structure and implementation method can adopt the prior art.

Apparently, the above-mentioned embodiments are only examples for clear description, rather than limiting the implementation. For those of ordinary skill in the art, other changes or changes in different forms can be made on the basis of the above description. It is not necessary and impossible to exhaustively list all the implementation manners here. However, the obvious changes or changes derived therefrom are still within the scope of protection of the present application.

Claims

A device for removing blood vessel agglomerates, characterized in that it comprises:

The clearing mechanism includes a core wire (1) and an arching member (2), the arching member (2) has a retracted state and an arched state, one end of which is connected to the core wire (1) at a set position;

The power assembly includes a first drive unit (3) and a second drive unit. The first drive unit (3) is connected to the core wire (1) and drives the core wire (1) to rotate. The arch When the lifting part (2) is in the arched state, the core wire (1) drives the arching part (2) to break the agglomerates;

The second drive unit is connected to an end of the arching member (2) away from the set position, and the second drive unit is adapted to move toward the set position under the action of an external force, so that the The arched part (2) is transformed into an arched state from a folded state.
The device for removing blood vessel agglomerates according to claim 1, characterized in that, the second driving unit is slidably connected with the first driving unit (3).
The device for removing blood vessel agglomerates according to claim 2, characterized in that, the removal mechanism further comprises a sleeve (4), the sleeve (4) is sleeved on the core wire (1), and one end of the sleeve (4) is It is connected with the arching piece (2), and the other end is adapted to move toward the set position under the action of the second driving unit.
The device for removing blood vessel agglomerates according to claim 3, wherein the second driving unit comprises:

A connection sleeve (5), one end close to the set position is connected with the sleeve (4), and the other end is slidably connected with the first drive unit (3).
The device for removing blood vessel agglomerates according to claim 4, further comprising a handle (6), and the first driving unit (3) is connected to the handle (6).
The device for removing blood vessel agglomerates according to claim 5, characterized in that, the handle (6) is provided with a snap-in structure (11), and the connecting sleeve (5) is connected to the The clamping structure (11) is connected.
According to the device for removing blood vessel agglomerates according to any one of claims 3-6, it is characterized in that it also includes a suction tube (12), which is sleeved on the outside of the sleeve (4), and is connected with the sleeve ( 4) A set gap is formed between the outer walls for absorbing broken agglomerates or injection solutions.
The device for removing blood vessel agglomerates according to claim 7, characterized in that it further comprises a communication piece (13), the communication piece (13) is connected with the suction tube (12), and is suitable for the extraction device (23) The broken agglomerates are extracted through the set gap.
The device for removing blood vessel agglomerates according to claim 8, characterized in that, the communication member (13) includes a first interface (14) and a second interface (15) that communicate with each other; the suction tube (12 ) is slidingly connected with the first interface (14), and the second interface (15) is adapted to be connected with the extracting device (23).
The device for removing blood vessel agglomerates according to claim 9, characterized in that, the connecting member (13) further includes a third interface (16), and the core wire (1) passes through the third interface (16) ) is connected with the first drive unit (3), and the sleeve (4) passes through the third interface (16) and is connected with the second drive unit.
The device for removing blood vessel agglomerates according to claim 10, further comprising a seal (17), the seal (17) is arranged at the third interface (16) to close the first The space between the three interfaces (16) and the sleeve (4).
The device for removing blood vessel agglomerates according to claim 11, characterized in that, the second driving member (9) comprises a sliding sleeve (18) connected with the connecting member (13), and the sliding sleeve (18) ) is provided with an installation groove (19), and the seal (17) is arranged in the installation groove (19) and abuts against the end surface of the third interface (16).
The device for removing blood vessel agglomerates according to claim 9, characterized in that, part of the communicating member (13) is connected to the suction tube (12), and the other part is connected to the second driving unit to maintain The relative position between the suction tube (12) and the arched piece (2).
The device for removing blood vessel agglomerates according to claim 13, characterized in that, the suction tube (12) includes a sliding part (20) that is slidably connected with the connecting member (13);

The suction tube (12) has a clearing state and a protection state; when the suction tube (12) is in the protection state, the sliding part (20) moves toward the set position and covers the arched part (2 ); when the suction tube (12) is in the clearing state, the sliding part (20) moves away from the set position to expose the arching member (2).
A system with a device for removing blood vessel agglomerates, characterized in that it includes the device for removing blood vessel agglomerates described in any one of claims 7-14, and also includes an extraction device (23), which is connected to the suction tube ( 12) is connected to one end away from the arched part (2).