WO2023283250A1 - Impulseur partiellement déformable et pompe d'assistance circulatoire pour cathéter incorporant cet impulseur - Google Patents

Impulseur partiellement déformable et pompe d'assistance circulatoire pour cathéter incorporant cet impulseur Download PDF

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Publication number
WO2023283250A1
WO2023283250A1 PCT/US2022/036235 US2022036235W WO2023283250A1 WO 2023283250 A1 WO2023283250 A1 WO 2023283250A1 US 2022036235 W US2022036235 W US 2022036235W WO 2023283250 A1 WO2023283250 A1 WO 2023283250A1
Authority
WO
WIPO (PCT)
Prior art keywords
impeller
diameter
blood pump
periphery
sheath
Prior art date
Application number
PCT/US2022/036235
Other languages
English (en)
Inventor
Peter G. Piferi
Original Assignee
Fbr Medical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fbr Medical, Inc. filed Critical Fbr Medical, Inc.
Priority to EP22748185.0A priority Critical patent/EP4366817A1/fr
Priority claimed from US17/858,615 external-priority patent/US20230008168A1/en
Publication of WO2023283250A1 publication Critical patent/WO2023283250A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A61M60/806—Vanes or blades
    • A61M60/808—Vanes or blades specially adapted for deformable impellers, e.g. expandable impellers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
    • A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
    • A61M60/414—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/827—Sealings between moving parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/827—Sealings between moving parts
    • A61M60/829—Sealings between moving parts having a purge fluid supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/865—Devices for guiding or inserting pumps or pumping devices into the patient's body

Definitions

  • the intervention typically lasts for less than a week, but can continue for several weeks.
  • These interventions include pharmaceuticals and/or medical devices, including cardiac-assist devices.
  • a partially deformable impeller in accordance with the present teachings can be slightly larger than, for example, the fixed-diameter impeller disclosed in the ⁇ 95 patent.
  • FIG. 2C depicts a second configuration of the distal portion of the catheter blood pump of FIG. 1A.
  • FIG. 8 shows a portion of one of impeller blades 782
  • the thickness of the blade is varied.
  • blades 782 are relatively thinner at periphery 786 and relatively thicker in substantially non-deformable portion 784, with thickness gradually increasing toward hub 780.
  • the transition is not gradual, but rather more of a "step" change.
  • the catheter blood pump is physically adapted to achieve two main configurations/states, including:
  • the pump assembly There are several potential placement locations for the pump assembly. Most preferred for the illustrative embodiment of the catheter blood pump is across the aortic valve. Other potential locations include the ascending aorta or within the left ventricle. Such locations will require additional features, such as a "snorkel" for crossing the aortic valve.
  • the pump assembly can be sited in other less-preferred locations, such as, without limitation, in the descending aorta, in suitably-sized peripheral blood vessels, or even in the right side of the heart or in right-side-related vasculature. At such alternate locations, one or more modifications are required to the illustrative embodiment, which, in conjunction with the present disclosure, are within the capabilities of those skilled in the art. For example, if sited in the right-side-of-the-heart or in right-side-related vasculature, modifications would be required to the impeller design, impeller rotation direction, as well as other features.
  • the impeller housing includes a plurality of holes disposed proximate to the proximal end thereof, through which blood flows out of the impeller housing during operation of the catheter blood pump;
  • an actuator that includes a first slideable member and a second slideable member, each independently movable in the axial direction, wherein the first slideable member physically couples to a proximal end of the sheath, and the second slideable member is operatively coupled to the impeller housing, and wherein the actuator further includes a motor;

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Mechanical Engineering (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne un impulseur partiellement déformable qui possède au moins deux pales, une périphérie de chaque pale étant déformable, la périphérie représentant les 5 à 20 % les plus externes de la largeur de la pale. Dans certains modes de réalisation, une pompe d'assistance circulatoire pour cathéter incorpore l'impulseur partiellement déformable.
PCT/US2022/036235 2021-07-07 2022-07-06 Impulseur partiellement déformable et pompe d'assistance circulatoire pour cathéter incorporant cet impulseur WO2023283250A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22748185.0A EP4366817A1 (fr) 2021-07-07 2022-07-06 Impulseur partiellement déformable et pompe d'assistance circulatoire pour cathéter incorporant cet impulseur

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202163219257P 2021-07-07 2021-07-07
US63/219,257 2021-07-07
US17/858,615 2022-07-06
US17/858,615 US20230008168A1 (en) 2021-07-07 2022-07-06 Partially-deformable impeller and catheter blood pump incorporating same

Publications (1)

Publication Number Publication Date
WO2023283250A1 true WO2023283250A1 (fr) 2023-01-12

Family

ID=82742646

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/036235 WO2023283250A1 (fr) 2021-07-07 2022-07-06 Impulseur partiellement déformable et pompe d'assistance circulatoire pour cathéter incorporant cet impulseur

Country Status (1)

Country Link
WO (1) WO2023283250A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007112033A2 (fr) * 2006-03-23 2007-10-04 The Penn State Research Foundation Dispositif d'assistance cardiaque avec une pompe a impulseur extensible
US9962475B2 (en) 2011-01-06 2018-05-08 Tc1 Llc Percutaneous heart pump
WO2018226991A1 (fr) * 2017-06-07 2018-12-13 Shifamed Holdings, Llc Dispositifs de déplacement de fluide intravasculaire, systèmes et procédés d'utilisation
US10668195B2 (en) 2018-06-01 2020-06-02 Fbr Medical, Inc. Catheter pump with fixed-diameter impeller
CN111773460A (zh) * 2020-06-12 2020-10-16 中国医学科学院阜外医院 血泵转子
CN111840681A (zh) * 2020-06-30 2020-10-30 浙江迪远医疗器械有限公司 血液泵及心脏导管
CN212940997U (zh) * 2020-05-27 2021-04-13 浙江大学 泵转子

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007112033A2 (fr) * 2006-03-23 2007-10-04 The Penn State Research Foundation Dispositif d'assistance cardiaque avec une pompe a impulseur extensible
US9962475B2 (en) 2011-01-06 2018-05-08 Tc1 Llc Percutaneous heart pump
WO2018226991A1 (fr) * 2017-06-07 2018-12-13 Shifamed Holdings, Llc Dispositifs de déplacement de fluide intravasculaire, systèmes et procédés d'utilisation
US10668195B2 (en) 2018-06-01 2020-06-02 Fbr Medical, Inc. Catheter pump with fixed-diameter impeller
CN212940997U (zh) * 2020-05-27 2021-04-13 浙江大学 泵转子
CN111773460A (zh) * 2020-06-12 2020-10-16 中国医学科学院阜外医院 血泵转子
CN111840681A (zh) * 2020-06-30 2020-10-30 浙江迪远医疗器械有限公司 血液泵及心脏导管

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