WO2023231186A1 - Bending-adjustable delivery system - Google Patents

Abstract

Provided is a bending-adjustable delivery system, comprising a control mechanism (20). The control mechanism (20) comprises a control handle (21), a control catheter (22), and a bending-adjusting wire (243). A proximal end of the control catheter (22) is fixed to the control handle (21). The control mechanism (20) is further provided with a control channel (25) passing through the control handle (21) and the control catheter (22). The control catheter (22) is further provided with a wire channel (220). The bending-adjusting wire (243) is movably arranged in the wire channel (220). A proximal end of the bending-adjusting wire (243) is connected to the control handle (21), while a distal end of the bending-adjusting wire (243) is connected to a distal end of the control catheter (22). The control mechanism (20) of the bending-adjustable delivery system has relatively high controllability, and can achieve accurate positioning and improve the implantation precision of a clamping apparatus (30).

Description

Adjustable bend delivery system Technical field

The present invention relates to the medical field, and further relates to an adjustable delivery system.

Background technique

Human valves mainly include arterial valves, venous valves and atrioventricular valves. The main function of the valves is to prevent blood reflux and play a very important role in human blood circulation. The atrioventricular valve is a valve that connects the atria and ventricles of the heart and prevents blood from flowing back into the atria.

Many mechanical defects in the atrioventricular valves or ventricles, such as valve leaflets, valve chordae tendineae connecting the valve leaflets and papillary muscles, damage to the papillary muscles or ventricular walls, may cause blood to flow back at the atrioventricular valves, that is, valve regurgitation . Valvular regurgitation can cause the valve annulus to become damaged, dilated, or weakened, limiting the valve's ability to fully close against the high pressure in the ventricle, which may further aggravate valvular regurgitation.

The most common treatment for valvular regurgitation relies on valve replacement or repair, which involves reshaping of the valve leaflets and annulus. Valve remodeling is often called valvuloplasty. Techniques for valve repair rely on suturing adjacent segments of opposing leaflets together and are often referred to as the "tie," "edge-to-edge," or "edge-to-edge" technique.

Clinical studies have shown that suture repair of the mitral valve is very effective, but this technique often relies on open heart surgery, during which the patient's chest is usually cut through a sternotomy and the patient is placed on a cardiopulmonary switch. flow. The surgical procedure of opening a patient's chest and placing the patient on a bypass is invasive and has a high rate of mortality and morbidity.

Minimally invasive catheter-based procedures have been developed to deliver clipping devices to incompetent valves, such as by holding portions of the leaflets together to reduce reflux. The clipping device is delivered through the femoral vein in a minimally invasive interventional manner, which can effectively perform suture repair of the valve. The above process places higher requirements on the precise positioning capability and controllability of the instrument system. The design of the device system usually adopts a larger size to achieve the above-mentioned functional purpose. The damage caused by the device to the human body due to the larger size has become a major hidden danger in the above-mentioned repair process.

Contents of the invention

In view of the above technical problems, the purpose of the present invention is to provide an adjustable and bendable delivery system. The control mechanism of the adjustable and bendable delivery system has high maneuverability, can achieve precise positioning, and can improve the efficiency of implantation of the clamping instrument. Accuracy.

In order to achieve the above objects, the present invention provides an adjustable and curved delivery system, including:

The control mechanism includes a control handle, a control conduit and a bending cable. The proximal end of the control conduit is fixed to the control handle. The control mechanism also has a control channel that passes through the control handle and the control conduit; The bending cable is movably installed on the control conduit;

The control handle includes a body part, the body part includes a body shell, a bending component installed on the body shell, and a control component installed on the body shell. The proximal end of the bending cable is connected to The distal end of the bending component is connected to the distal end of the control catheter;

Also comprising a clamping instrument adapted to be mounted on the distal end of the manipulation catheter;

The control mechanism also includes a control pull wire movably installed in the control channel. The proximal end of the control pull wire is connected to the control component, and the distal end is suitable for connection to the clamping instrument to operate the control The assembly controls the movement of the control cable to control the clamping device.

In some preferred embodiments, the bending assembly includes a base block, a winding wheel, and a knob. The base block has a receiving channel. The proximal end of the control catheter is installed in the receiving channel. The winding wheel can Rotally installed on the base block and located on one side of the accommodation channel, the knob is connected to the reel, and the proximal end of the bending cable is connected to the reel.

In some preferred embodiments, the bending assembly includes a base block, a first reel, a second reel, a third reel, a first knob and a second knob, the first reel and The second reels are rotatably mounted on the base block and are located on both sides of the accommodation channel, the third reels are rotatably mounted on the base block, and the first knob Connected to the first reel, and at least a portion of the first knob extends to the outside of the body housing, the first reel is connected to the second reel, and rotates the third A knob can drive the first reel and the second reel to rotate in opposite directions, and the second knob is connected to the third reel;

The bending cable includes a first bending cable, a second bending cable, and a third bending cable, and the proximal ends of the first bending cable, the second bending cable, and the third bending cable They are respectively connected to the first winding wheel, the second winding wheel and the third winding wheel, and the distal ends are respectively connected to different positions of the distal end of the control catheter.

In some preferred embodiments, the distal ends of the first bending cable, the second bending cable and the third bending cable are arranged in a substantially triangular shape.

In some preferred embodiments, the straight line where the distal ends of the first bending pull wire and the second bending pull wire are located passes through the center of the control catheter.

In some preferred embodiments, the bending assembly further includes a driving gear installed on the first reel and a driven gear installed on the second reel, and the driving gear is connected with the driven gear. The moving gear meshes.

In some preferred embodiments, the bending assembly further includes a first knob post and a second knob post, one end of the first knob post is connected to the first knob, and the other end is connected to the first winding wheel; one end of the second knob column is connected to the second knob, and the other end is connected to the third reel; the first knob column and the second knob column are respectively provided with blocking members, The base block is provided with a resistance member, and the blocking member is in contact with the resistance member.

In some preferred embodiments, the control assembly includes a capture pull wire and a locking pull wire, and the control pull wire includes a capture pull wire and a locking pull wire, and the distal ends of the capture pull wire and the locking pull wire are respectively connected to the In the clamping instrument, the proximal ends of the catching pull wire and the locking pull wire are connected to the catching pull wire rod and the locking pull wire rod respectively; the body part has a pull wire cavity, and the catching pull wire rod and the locking pull wire are The distal ends of the locking cable levers are respectively movably installed in the cable cavities of the body part.

In some preferred embodiments, a set of first latches are respectively provided on the upper and lower sides of the catching pull rod and/or the locking pull rod, and a set of second latches are respectively provided on the upper and lower inner walls of the cord cavity. teeth, when the first latch teeth are engaged with the second latch teeth, the first latch teeth and the second latch teeth engage with each other to limit the position, the catching pull rod and/or the The locking wire lever cannot move axially in the wire cavity; rotating the catching wire lever and/or the locking wire lever causes the first latching teeth and the second latching teeth to stagger each other, and the catching wire lever The cable catching lever and/or the locking cable lever can move in the cable cavity.

In some preferred embodiments, the distal end of the catching wire rod and/or the locking wire rod is threadedly connected to the wire pulling cavity, and the catching wire rod and/or the locking wire rod are respectively rotatable. A sliding block is installed on the ground, and the proximal end of the catching pull wire and/or the locking pull wire is fixed to the sliding block.

In some preferred embodiments, the control handle further includes a base portion connected to the proximal end of the body portion;

The control mechanism also includes a delivery rod movably installed in the control channel. The distal end of the delivery rod and the distal end of the control pull wire are respectively adapted to be connected to the clamping instrument for controlling the The clamping device described above;

The base part includes a base shell and a delivery component installed on the base shell. The delivery component is connected to the proximal end of the delivery rod and is used to control the axial movement of the delivery rod.

In some preferred embodiments, the delivery assembly includes a delivery gear and a delivery knob. The delivery gear and the delivery knob are respectively installed on the inner and outer sides of the base shell. The proximal end of the delivery rod is located on the base. Inside the shell, a number of meshing teeth are provided at a preset position at the proximal end of the delivery rod. The delivery gear meshes with the meshing teeth on the delivery rod. Rotating the delivery knob can drive the delivery gear to rotate. , the delivery gear can drive the delivery rod to move axially.

In some preferred embodiments, the delivery rod is formed by at least one layer of metal wires arranged and surrounded in sequence.

In some preferred embodiments, the delivery rod includes a distal section, a proximal section and a transition element between the distal section and the proximal section, the proximal section being formed by winding a wire. The distal section is formed by spirally winding elastic wire, and the diameter of the distal section is smaller than the diameter of the proximal section.

In some preferred embodiments, the adjustable-bend delivery system further includes a guiding mechanism, including a guiding handle and a guiding catheter, and the proximal end of the guiding catheter is fixed to the guiding The handle, the guide mechanism also has a guide channel that passes through the guide handle and the guide catheter, the control catheter is suitable for installation in the guide channel, and the distal end of the control catheter is suitable for Pass through the guide channel.

In some preferred embodiments, the conduit forming the control channel is formed by at least one layer of metal wires arranged and surrounded in sequence.

In some preferred embodiments, the guide handle includes a guide body and a steering assembly installed on the guide body, the guide mechanism also includes a steering pull wire, the proximal end of the steering pull wire is connected to the steering Assembly, the distal end of the steering cable is connected to the distal end of the guiding catheter, and operating the steering assembly can drive the steering cable to move axially to adjust the angle of the distal end of the guiding catheter.

In some preferred embodiments, the control mechanism further includes a connecting post provided at the distal end of the control catheter;

The clamping instrument includes a bracket, an attachment post, an anchoring arm, a clamping arm and an actuating rod. The distal end of the attachment post is fixed to the bracket, and the proximal end is detachably connected to the distal end of the connecting post. end, the anchor arm and the clamping arm are respectively rotatably installed on the bracket, the actuating rod is movably installed in the attachment column, and the distal end of the actuating rod is connected to the clamping arm, the proximal end of the actuating rod is detachably connected to the distal end of the delivery rod;

The proximal end of the capture pull wire is connected to the control handle, and the distal end is connected to the anchor arm. Moving the capture pull wire can drive the anchor arm to rotate relative to the bracket.

In some preferred embodiments, the clamping instrument further includes a locking mechanism, the locking mechanism includes a locking block and an elastic element, the locking block is rotatably mounted on the distal end of the bracket, the locking block has a locking end and connecting end, the elastic element is provided between the locking block and the bracket;

The proximal end of the locking pull wire is connected to the control handle, and the distal end is connected to the connecting end of the locking block;

In the locked state, the locking end is in contact with the distal end of the actuating rod; pulling the locking wire drives the locking block to rotate and compress the elastic element, and the locking end is separated from the actuating rod.

In some preferred embodiments, the distal end of the bracket has a locking groove, the locking block is rotatably installed in the locking groove, and the elastic element is installed in the locking groove and abuts against The locking block.

In some preferred embodiments, the bracket is a hollow structure including two opposite outer walls, and a receiving space is formed between the two opposite outer walls. The connecting end of the clamping arm has an inner hole and an outer hole, so The connecting end of the clamping arm extends into the accommodating space of the bracket, and the outer hole and the bracket are rotatably connected by a pin and can rotate around the pin.

Compared with the existing technology, the adjustable delivery system provided by the present invention has at least one of the following beneficial effects:

1. The adjustable-bending delivery system provided by the present invention. The control mechanism of the adjustable-bending delivery system has high maneuverability, can achieve precise positioning, and can improve the accuracy of implantation of the clamping instrument;

2. The adjustable and bendable delivery system provided by the present invention can complete the implantation of the clamping device through the cooperation of the guide mechanism and the control mechanism, and can effectively reduce the entry of the adjustable and bendable delivery system. The external size of the human body part makes it easier to pass through human blood vessels and atrial septum, making it less likely to cause surgical defects to the atrial septum;

3. In the adjustable and bendable delivery system provided by the present invention, the distal end of the control handle is provided with a body part, and the proximal end is provided with a base part. The body part is provided with a bending component and a control component, respectively used to control the angle of the distal end of the catheter. and a state of the clamping instrument, the base being provided with a delivery assembly for controlling axial movement of the delivery rod;

4. In the adjustable bending delivery system provided by the present invention, the first winding wheel and the second winding wheel of the bending assembly mesh with each other through the driving gear and the impulse gear. Rotating the first knob can drive the first winding wheel. It rotates in the opposite direction with the second winding wheel to adjust the angle of the distal end of the control catheter.

Description of the drawings

The following will describe the preferred embodiments in a clear and easy-to-understand manner with reference to the accompanying drawings, and further explain the above-mentioned characteristics, technical features, advantages and implementation methods of the present invention.

Figure 1 is a schematic three-dimensional structural diagram of an adjustable and bendable delivery system according to a preferred embodiment of the present invention;

Figure 2 is a schematic exploded view of the adjustable bend delivery system according to the preferred embodiment of the present invention;

Figure 3 is a schematic three-dimensional structural diagram of the distal end of the adjustable and bendable delivery system according to the preferred embodiment of the present invention;

Figure 4 is a schematic structural diagram of the distal side of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 5 is a schematic diagram of the distal cross-sectional structure of the adjustable and bendable delivery system according to the preferred embodiment of the present invention;

Figure 6 is a schematic diagram of the distal structure of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 7 is a schematic diagram of the connection structure between the clamping instrument and the control catheter of the adjustable-bend delivery system according to the preferred embodiment of the present invention;

Figure 8 is a schematic structural diagram of the control handle side of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 9 is a cross-sectional view along line A-A in Figure 8;

Figure 10 is a cross-sectional view along line B-B in Figure 8;

Figure 11 is a side view of the control handle of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 12 is a cross-sectional view along line C-C in Figure 11;

Figure 13 is a schematic three-dimensional structural diagram of the bending assembly of the control handle of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 14 is a schematic top view of the bending assembly of the control handle of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 15 is a cross-sectional view along line D-D in Figure 14;

Figure 16 is a schematic structural diagram of the control catheter of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 17 is a schematic cross-sectional structural view of the control catheter of the adjustable delivery system according to the preferred embodiment of the present invention;

Figures 18 and 19 are schematic structural views of the guide handle of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 20 is a cross-sectional view along line E-E in Figure 19;

Figure 21 is a schematic three-dimensional structural diagram of the steering assembly of the guide handle of the adjustable delivery system according to the preferred embodiment of the present invention;

Figure 22 is a schematic cross-sectional structural view of the guide catheter of the adjustable delivery system according to the preferred embodiment of the present invention;

Figures 23 and 24 are schematic structural views of the control catheter of the adjustable-bend delivery system according to the preferred embodiment of the present invention;

Figure 25 is a schematic structural diagram of the delivery rod of the adjustable and bendable delivery system according to the preferred embodiment of the present invention;

Figure 26 is an application diagram of the adjustable bend delivery system according to the preferred embodiment of the present invention;

Figure 27 is an operational schematic diagram of the adjustable bend delivery system according to the preferred embodiment of the present invention;

Figure 28 is a schematic three-dimensional structural diagram of the stent of the adjustable and bendable delivery system according to the preferred embodiment of the present invention.

Explanation of reference numbers:

Guide mechanism 10, guide handle 11, guide body 111, guide chuck 1111, guide flushing head 1112, first snap-in slot 1113, second snap-in slot 1114, steering assembly 112, steering base block 1121, Installation channel 1120, steering knob 1123, steering link 1124, knob gear 1125, gear plate 1126, first steering assembly 1127, second steering assembly 1128, hemostatic valve 113, valve cap 1131, propulsion part 1132, flow blocking member 1133, Guide catheter 12, inner catheter 121, middle catheter 122, outer catheter 123, steering channel 124, guide channel 13, steering cable 14, first steering cable 141, second steering cable 142, control mechanism 20, control Handle 21, base 211, base shell 2111, delivery component 2112, delivery gear 21121, delivery knob 21122, anti-rotation pin 2113, body part 212, body shell 2121, exhaust hole 2120, bending component 2122, base block 21221, Accommodating channel 21220, first reel 21222, second reel 21223, third reel 21224, first knob 21225, second knob 21226, driving gear 21227, driven gear 21228, first knob column 21231, Second knob column 21232, first blocking member 21233, first resistance member 21234, second blocking member 21235, second resistance member 21236, control assembly 2124, capture wire lever 21241, locking wire lever 21242, rod body 2161, rod cap 2162, flow blocking member 2163, holding member 2164, cable cavity 2127, first latch 21271, second latch 21272, fixed component 2129, control conduit 22, cable channel 220, developing element 221, bending channel 222, control Pipe 223, delivery rod 23, meshing teeth 231, delivery rod handle 232, delivery rod clamp 233, anti-rotation plane 2331, delivery rod base rod 234, distal section 2351, proximal section 2352, transition element 2353, control cable 24 , control cable 241, locking cable 2412, capture cable 2411, bending cable 243, first bending cable 2431, second bending cable 2432, third bending cable 2433, control channel 25, connecting column 26, connecting element 261, protruding portion 2611, clamping instrument 30, bracket 31, locking groove 310, accommodation space 311, attachment column 32, connecting hub 321, connecting hole 3210, anchoring arm 33, anchoring hook 330, clamping arm 34 , clamping hole 340, actuation rod 35, central pin 351, limiting protrusion 352, locking mechanism 36, locking block 361, locking end 3611, connecting end 3612, elastic element 362, blocking film 37, bracket 40, base 41. The first slider 42, the second slider 43, the first adjustment button 44, and the second adjustment button 45.

Detailed ways

In order to explain the embodiments of the present invention or technical solutions in the prior art more clearly, the specific implementation modes of the present invention will be described below with reference to the accompanying drawings. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without exerting creative efforts, other drawings can also be obtained based on these drawings, and obtain Other embodiments.

In order to keep the drawings concise, only the parts related to the invention are schematically shown in each figure, and they do not represent the actual structure of the product. In addition, in order to make the drawings concise and easy to understand, in some drawings, only one of the components with the same structure or function is schematically illustrated or labeled. In this article, "a" not only means "only one", but can also mean "more than one".

It will be further understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items. .

In this article, it should be noted that, unless otherwise clearly stated and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense. For example, it can be a fixed connection or a detachable connection, or Integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be an internal connection between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood on a case-by-case basis.

In addition, in the description of the present application, the terms "first", "second", etc. are only used to differentiate the description and cannot be understood as indicating or implying relative importance.

Referring to FIGS. 1 to 28 , the adjustable delivery system provided by the preferred embodiment of the present invention includes a control mechanism 20 . The control mechanism 20 includes a control handle 21, a control catheter 22 and a control wire 24. The control wire 24 also includes a bending wire 243. The proximal end of the control catheter 22 is fixed to the control handle 21. The control mechanism 20 also has a control channel 25 that runs through the control handle 21 and the control conduit 22; the control conduit 22 also has a wire channel 220, and the bending wire 243 is movably installed in the wire channel 220. The proximal end of the bending cable is connected to the control handle 21 , and the distal end is connected to the distal end of the control catheter 22 .

The adjustable bend delivery system also includes a guide mechanism 10 and a clamping instrument 30 , the control mechanism 20 also includes a delivery rod 23 , and the control pull wire 24 includes a control pull wire 241 . The guide mechanism 10 includes a guide handle 11 and a guide catheter 12 . The proximal end of the guide catheter 12 is fixed to the guide handle 11 . The guide mechanism 10 also has a guide handle 11 that passes through the guide handle 11 . and the guide channel 13 of the guide catheter 12 , the control catheter 22 is adapted to be installed in the guide channel 13 , and the distal end of the control catheter 22 passes through the guide channel 13 . The clamping instrument 30 is suitable for being installed on the distal end of the control catheter 22, and the distal end of the delivery rod 23 and the distal end of the control pull wire 241 are respectively adapted to be connected to the clamping instrument 30 for use. The clamping device 30 is controlled.

Referring to Figures 26 and 27, the guide mechanism 10 and the manipulation mechanism 20 can control the preset position of the clamping instrument 30 implanted in the heart, and the manipulation mechanism 20 can manipulate the clamping The instrument 30 is oriented to hold a portion of the leaflets together by the clamping instrument 30, thereby reducing reflux. The control mechanism 20 has high maneuverability, can achieve precise positioning, and can improve the accuracy of implantation of the clamping instrument 30 .

It should be noted that the adjustable and bendable delivery system formed by the guide mechanism 10 , the control mechanism 20 and the clamping instrument 30 can pass through the guide mechanism 10 and the control mechanism 20 . Blood vessels accurately deliver the clamping device 30 to the target implantation site, especially the femoral vein blood vessels deliver the clamping device 30 to the mitral valve between the left atrium and the left ventricle, and can be controlled outside the human body. The clipping device 30 performs operations of capturing, clipping, and detaching from the delivery system at the mitral valve.

It should also be pointed out that in this preferred embodiment, the bending cable 243 of the control mechanism 20 and the control handle 21 can control the bending of the distal end of the control catheter 22, and the control mechanism 20 and The two-layer conduit structure formed by the mutual cooperation of the guide mechanism 10 can complete the delivery of the clamping device 30, so that the external size of the part of the adjustable and bendable delivery system that enters the human body is reduced, and the adaptability to the human body is stronger. In particular, it is easier to pass through blood vessels and the interatrial septum, and it is less likely to cause surgical defects to the atrial septum.

Referring to FIGS. 3 , 4 , 5 and 6 , further, the control mechanism 20 further includes a connecting post 26 provided at the distal end of the control catheter 22 . The clamping instrument 30 includes a bracket 31, an attachment post 32, an anchoring arm 33, a clamping arm 34 and an actuating rod 35. The distal end of the attachment post 32 is fixed to the bracket 31, and the proximal end is detachable. Connected to the distal end of the connecting column 26, the clamping arm 34 is rotatably mounted on the bracket 31, and the anchoring arm 33 is movably mounted on the bracket 31 and can move closer to or farther away from the attachment. Post 32, the actuating rod 35 is movably installed in the attachment post 32, and the distal end of the actuating rod 35 is connected to the clamping arm 34, and the proximal end of the actuating rod 35 Detachably connected to the distal end of the delivery rod 23 , axial movement of the actuation rod 35 can drive the clamping arm 34 to rotate relative to the bracket 31 .

The control pull wire 241 includes a capture pull wire 2411. The proximal end of the capture pull wire 2411 is connected to the control handle 21, and the distal end is connected to the anchor arm 33. The axial movement of the capture pull wire 2411 can drive all The anchor arm 33 is positioned close to or away from the attachment post 32 .

Further, the clamping instrument 30 further includes a locking mechanism 36 . The locking mechanism 36 includes a locking block 361 and an elastic element 362. The distal end of the bracket 31 has a locking groove 310. The locking block 361 is rotatably installed in the locking groove 310. The locking block 361 It has a locking end 3611 and a connecting end 3612. The elastic element 362 is installed in the locking groove 310 and abuts against the locking block 361.

The control wire 24 further includes a locking wire 2412 , the proximal end of the locking wire 2412 is connected to the control handle 21 , and the distal end is connected to the connecting end 3612 of the locking block 361 . In the locked state, the locking end 3611 is in contact with the distal end of the actuating rod 35; pulling the locking wire 2412 drives the locking block 361 to rotate so that the locking end 3611 is separated from the actuating rod 35. And compress the elastic element 362. After the locking wire 2412 is released, the locking block 361 is pushed to rotate back to its original position under the action of the elastic restoring force of the elastic element 362, and the locking end 3611 abuts the actuating rod 35 to lock the locking block 361. The actuating rod 35 performs position limiting.

Referring to FIGS. 3 and 4 , a developing element 221 is provided at the distal end of the control catheter 22 for marking the position of the distal end of the control catheter 22 to facilitate the operator's operation. Preferably, the developing element 221 surrounds the distal end of the control catheter 22 in a ring shape.

Referring to FIGS. 3 to 6 , the proximal end of the attachment post 32 is provided with a connection hub 321 , and the proximal end of the connection hub 321 is detachably connected to the distal end of the connection post 26 . The distal end is fixed to the attachment post 32 .

The side wall of the connecting hub 321 is provided with a connecting hole 3210. The distal end of the connecting post 26 is provided with at least one connecting element 261 . The proximal end of the connecting element 261 is rotatably connected to the connecting post 26 . The distal end of the connecting element 261 is provided with a protruding portion 2611 . A part of the connecting element 261 extends into the interior of the connecting hub 321 , and the protruding portion 2611 extends into the connecting hole 3210 . The proximal end of the actuating rod 35 extends into the interior of the connecting hub 321, and the distal end of the delivery rod 23 extends from the interior of the connecting column 26 to the interior of the connecting hub 321 and is connected with the actuating rod 321. The proximal end of rod 35 is removably connected. At this time, the delivery rod 23 is in contact with the connecting element 261, and the space in the connecting hub 321 is not enough to allow the protruding portion 2611 to escape from the connecting hole 3210, and the control tube 22 is connected to the connecting hole 3210. The clamping device 30 remains connected.

After the distal end of the delivery rod 23 is separated from the proximal end of the actuating rod 35, the delivery rod 23 can be separated from the connecting element 261, and the protruding portion 2611 of the connecting element 261 can be separated from the connecting element 261. If the connecting hole 3210 of the connecting hub 321 is disengaged, the control tube 22 can be separated from the clamping instrument 30 .

Preferably, the distal end of the delivery rod 23 is threadedly connected to the proximal end of the actuating rod 35, and the connection or separation of the delivery rod 23 and the actuating rod 35 can be controlled by rotating the delivery rod 23. .

Referring to FIG. 4 , the clamping instrument 30 further includes a flow-blocking film 37 provided on the outside of the clamping arm 34 and the locking mechanism 36 .

The clamping arm 34 and the anchoring arm 33 are configured to cooperate with each other to clamp and fix target tissue therebetween, such as but not limited to valves.

The clamping arm 34 is provided with a clamping hole 340, and the anchoring arm 33 is provided with an anchoring hook 330. When the clamping arm 34 and the anchoring arm 33 are close enough, the anchoring hook 330 is provided. The hook 330 can extend into the clamping hole 340 to fix the valve between the clamping arm 34 and the anchoring arm 33 . Part of the anchoring hook 330 can extend into the target tissue to increase friction and improve the stability of target tissue fixation. The anchoring hook 330 has a small enough size to be separated from the captured target tissue. , and will not cause irreparable damage to the target tissue.

The bracket 31 is a hollow structure, including two opposite outer side walls at the front and rear, and an accommodating space 311 is formed between the two opposite outer side walls. The connecting end of the clamping arm 34 has an inner hole and an outer hole (not shown in the figure). The connecting end of the clamping arm 34 extends into the receiving space 311 of the bracket 31. The outer hole It is rotatably connected to the bracket 31 through a pin and can rotate around the pin.

A central pin 351 is provided at a preset position of the actuating rod 35 , and the central pin 351 is engaged with the inner hole of the clamping arm 34 . When the actuation rod 35 moves distally or proximally under the action of external force, it can drive the central pin 351 to move, and the central pin 351 can drive the clamping arm 34 relative to the bracket 31 Turn.

For example, when the actuation rod 35 is pulled to move proximally, the central pin 351 drives the clamping arm 34 to move in a direction away from the bracket 31, and the clamping arm 34 expands; When the actuation rod 35 moves distally, the central pin 351 drives the clamping arm 34 to move in a direction close to the bracket 31 , and the clamping arm 34 abuts against one side of the bracket 31 to form a closed state. The locking block 361 is in contact with the distal end of the actuating rod 35. When the locking mechanism 36 is in the locked state, the actuating rod 35 cannot be pulled, and the position of the clamping arm 34 is fixed.

The connecting end of the anchor arm 33 extends into the receiving space 311 of the bracket 31, and the connecting end of the anchor arm 33 is rotatably connected to the bracket 31. The distal end of the catching pull wire 2411 The end is connected to the anchor arm 33 , and pulling the catching pull wire 2411 can drive the anchor arm 33 to rotate relative to the bracket 31 .

Referring to Figure 5, it is shown that the clamping instrument 30 is in a closed state, the clamping arm 34 is disposed against the bracket 31; the locking mechanism 36 is in a locked state, and the actuating rod 35 is locked. In some variant embodiments, a plurality of locking grooves are provided at a preset position at the distal end of the actuating rod 35 for accommodating the locking end 3611 of the locking block 361 to improve the contact between the locking end 3611 and The friction force of the actuating rod 35 increases the locking strength and maintains the stability of the locking mechanism 36 in the locked state.

In some variant embodiments, the bottom wall of the accommodation space 311 of the bracket 31 is provided with an accommodation groove, and at least a part of the elastic element 362 is installed in the accommodation groove. In some variant embodiments, a receiving groove for accommodating the elastic element 362 is also provided at the preset position of the anchor arm 33 .

Referring to Figure 5, in some variant embodiments, the preset position of the actuating rod 35 is also provided with a limiting protrusion 352. The limiting protrusion 352 is a substantially circular plane or a column with a small height, preferably It is provided at the connection between the attachment column 32 and the bracket 31. The connection between the attachment column 32 and the bracket 31 can limit the range of movement of the actuating rod 35, limiting the actuating rod 35. The distance that the moving rod 35 moves to the proximal end.

Referring to Figures 8, 9 and 17, the control handle 21 includes a base portion 211 and a body portion 212. The base portion 211 is connected to the proximal end of the body portion 212. The control channel 25 passes through the base portion 211 and the body portion 212. Describe the main body part 212. The proximal end of the control catheter 22 is fixed to the body part 212 .

Further, the body part 212 includes a body shell 2121 and a bending assembly 2122. The bending assembly 2122 is installed on the body shell 2121. The distal end of the bending cable 243 is connected to the distal end of the control catheter 22, and the proximal end is connected to the bending assembly 2122. The bending assembly 2122 can be operated to tighten or loosen the bending cable 243. , to adjust the bending angle of the distal end of the control catheter 22 . The control conduit 22 also has a bending channel 222, and the bending wire 243 is installed in the bending channel 222.

Referring to Figure 17, preferably, the number of the bending pull wires 243 is three, which are the first bending pull wire 2431, the second bending pull wire 2432 and the third bending pull wire 2433. The ends are arranged in a substantially triangular shape, and the straight line where the distal ends of the first bending cable 2431 and the second bending cable 2432 are located passes through the center of the control conduit 22 . Correspondingly, the number of the bending channels 222 is also three, which are respectively used to accommodate the first bending cable 2431, the second bending cable 2432 and the third bending cable 2433.

The bending assembly 2122 includes a base block 21221, a reel and a knob. The base block 21221 has a receiving channel 21220. The proximal end of the control catheter 22 is installed in the receiving channel 21220. The reel is rotatable. The knob is connected to the reel, and the proximal end of the bending wire 243 is connected to the reel.

The reel includes a first reel 21222, a second reel 21223, and a third reel 21224; the knob includes a first knob 21225 and a second knob 21226. The first reel 21222 and the second reel 21223 are respectively rotatably installed on the base block 21221 and are located on both sides of the accommodation channel 21220. The third reel 21224 is rotatable. is installed on the base block 21221, the proximal end of the first bending pull wire 2431 is connected to the first winding wheel 21222, and the proximal end of the second bending pull wire 2432 is connected to the second winding wheel wheel 21223, and the proximal end of the third bending wire 2433 is connected to the third winding wheel 21224.

Preferably, the proximal ends of the first bending cable 2431 , the second bending cable 2432 and the third bending cable 2433 respectively pass through the proximal side wall of the control catheter 22 .

Referring to Figures 13 and 14, the bending assembly 2122 also includes a driving gear 21227 and a driven gear 21228. The driving gear 21227 is fixed to the first reel 21222, and the driven gear 21228 is fixed to the The second reel 21223, and the driving gear 21227 meshes with the driven gear 21228.

The first knob 21225 is connected to the first reel 21222, and at least a part of the first knob 21225 extends to the outside of the body shell 2121. Rotating the first knob 21225 can drive the second reel. A reel 21222 and the second reel 21223 rotate in opposite directions. When the first reel 21222 winds the first bending wire 2431, the second reel 21223 releases the first bending wire 2431. Second bending cable 2432; the second knob 21226 is connected to the third reel 21224, and at least a part of the second knob 21226 extends to the outside of the body shell 2121, turn the second knob 21226 can drive the third reel 21224 to rotate.

Preferably, the base block 21221 has three rotation grooves, and the first reel 21222, the second reel 21223 and the third reel 21224 are respectively installed on the three reels. in one of the rotating grooves.

In some variant embodiments, the driving gear 21227 is integrally formed with the first reel 21222, and the driven gear 21228 is integrally formed with the second reel 21223.

Preferably, the first knob 21225 and the second knob 21226 are respectively located on opposite sides of the body shell 2121, and the two knobs are offset, so that the space of the body shell 2121 can be fully utilized. Preferably, the first knob 21225 and the first reel 21222 are connected through a first knob post 21231, and the second knob 21226 and the third reel 21224 are connected through a second knob post. 21232 connections.

Referring to Figure 15, a first blocking member 21233 is provided at the preset position of the first knob column 21231, and the base block 21221 is provided with a first resistance member 21234 corresponding to the first blocking member 21233. The member 21233 abuts the first resistance member 21234, and the first knob post 21231 is limited by the friction force between the first blocking member 21233 and the first resistance member 21234, so that the first The knob post 21231 does not rotate spontaneously when no external force is applied. Correspondingly, a second blocking member 21235 is provided at the preset position of the second knob column 21232, and the base block 21221 is provided with a second resistance member 21236 corresponding to the second blocking member 21235. The second blocking member 21235 is in contact with the second resistance member 21236, and the second knob post 21232 is limited by the friction force between the second blocking member 21235 and the second resistance member 21236, so that the second knob Column 21232 does not rotate spontaneously when not acted upon by external forces.

Referring to Figure 8, the body part 212 also includes a control component 2124. The control component 2124 includes two pull wire rods. The two pull wire levers are a capture pull wire lever 21241 and a locking pull wire lever 21242. The capture pull wire The rod 21241 and the locking wire rod 21242 are respectively movably installed on the body shell 2121. The proximal end of the capturing wire 2411 is connected to the capturing wire rod 21241, and the proximal end of the locking wire 2412 is connected to the body shell 2121. Regarding the locking wire lever 21242, operating the catching wire lever 21241 can drive the capturing wire 2411 to move axially, and operating the locking wire lever 21242 can drive the locking wire 2412 to move axially.

The cable rod includes a rod body 2161, a rod cap 2162, a flow blocking part 2163 and a holding part 2164. The rod body 2161 is a hollow tube, and the proximal end of the catching pull wire 2411 or the locking pull wire passes through the rod body 2161 and is fixed between the rod cap 2162 and the proximal end of the rod body 2161. The flow blocking member 2163 is provided at the connection between the rod cap 2162 and the rod body 2161. The holding member 2164 extends outward from one side of the rod body 2161 to facilitate the operator to hold.

The main body shell 2121 also has a cable cavity 2127 at a preset position, and the distal ends of the catching cable rod 21241 and the locking cable rod 21242 are respectively movably installed in the cable cavity 2127.

Referring to Figure 10, a set of first latching teeth 21271 are respectively provided on the upper and lower sides of the cable lever, and a set of second latching teeth 21272 are respectively provided on the upper and lower inner walls of the cable cavity 2127. When the first latching teeth 21271 When engaged with the second latching teeth 21272, the first latching teeth 21271 and the second latching teeth 21272 are limited by mutual engagement, and the cable rod cannot move axially in the cable cavity 2127; Rotate the cable lever so that the first latching teeth 21271 and the second latching teeth 21272 are staggered from each other, so that the cable lever can be axially pulled in the cable cavity 2127 .

In some modified embodiments, the distal end of the pull wire rod is threadedly connected to the inner wall of the pull wire cavity 2127, and rotating the pull wire rod can control the pull wire rod to tighten or loosen the capture pull wire 2411 or the capture pull wire 2411. Described locking pull wire 2412. The cable lever also includes a sliding block (not shown in the figure), the proximal end of the catching wire 2411 or the locking wire 2412 is fixed to the sliding block, and the sliding block is rotatably installed on the The proximal end of the rod body 2161. When the rod body 2161 is rotated, the sliding block can rotate relative to the rod body 2161, thereby preventing or reducing the rotation of the catching pulling wire 2411 or the locking pulling wire 2412.

Referring to Figure 12, a fixing element 2129 is also provided in the pull wire cavity 2127. The delivery rod 23 extends from the base 211 through the fixing element 2129 to the distal end. The fixing element 2129 can improve the delivery rod. 23% stability, and also has the effect of preventing liquid leakage.

Referring to Figure 9, the base 211 includes a base shell 2111 and a delivery assembly 2112. The delivery assembly 2112 includes a delivery gear 21121 and a delivery knob 21122. The delivery gear 21121 and the delivery knob 21122 are respectively installed on the base shell 2111. the inner and outer sides. The proximal end of the delivery rod 23 is located in the base shell 2111, and a number of meshing teeth 231 are provided at the preset position of the proximal end of the delivery rod 23. The delivery gear 21121 engages with all the teeth on the delivery rod 23. The plurality of meshing teeth 231 can drive the delivery gear 21121 to rotate when rotating the delivery knob 21122, and the delivery gear 21121 can drive the delivery rod 23 to move axially.

Further, the delivery rod 23 further includes a delivery rod handle 232, a delivery rod clamp 233, and a delivery rod base 234. The distal end of the delivery rod clamp 233 is provided with a clamping groove, and the delivery rod base 234 has a clamping groove. The proximal end is fixed in the clamp groove, the delivery rod handle 232 is fixed on the proximal end of the delivery rod clamp 233, and at least a part of the delivery rod handle 232 is located outside the base shell 2111, and the operation is The delivery rod handle 232 can drive the delivery rod clamp 233 and the delivery rod base 234 to rotate. The engaging teeth 231 are formed on the outer side wall of the delivery rod clamp 233 .

Referring to FIG. 9 , the distal side of the delivery rod clamp 233 has an anti-rotation flat surface 2331 . The base 211 also includes an anti-rotation pin 2113. The anti-rotation pin 2113 is installed on the base shell 2111, and the anti-rotation pin 2113 abuts against the anti-rotation plane 2331 to prevent the delivery rod chuck. 233 rotates; when the anti-rotation pin 2113 is separated from the anti-rotation plane 2331, the delivery rod chuck 233 can rotate within the base shell 2111.

Furthermore, an exhaust hole 2120 is provided on one side of the body shell 2121 of the body part 212 , and the exhaust hole 2120 is connected with the cable cavity 2127 .

Referring to Figures 18, 19 and 20, the guide handle 11 includes a guide body 111 and a steering assembly 112. The steering assembly 112 is installed on the guide body 111.

Referring to FIG. 22 , the guide mechanism 10 further includes a steering wire 14 , the proximal end of the steering wire 14 is connected to the steering assembly 112 , and the distal end of the steering wire 14 is connected to the distal end of the guide catheter 12 . end, operating the steering assembly 112 can drive the steering cable 14 to move axially to adjust the angle of the distal end of the guide catheter 12 .

Specifically, the number of the steering assemblies 112 is two, and the number of the steering cables 14 is also two. The proximal ends of the two steering cables 14 are respectively connected to the two steering assemblies 112, and the two steering cables 14 are respectively connected to the two steering assemblies 112. The distal ends of the steering wires 14 are respectively connected to different distal positions of the guide catheter 12 . Preferably, the connection between the distal ends of the two steering wires 14 and the distal end of the guiding catheter 12 does not pass through the center of the guiding catheter 12 . The two steering cables 14 are respectively a first steering cable 141 and a second steering cable 142, and the two steering assemblies 112 are respectively a first steering assembly 1127 and a second steering assembly 1128. The first steering cable 141 The proximal end is connected to the first steering component 1127 , and the proximal end of the second steering pull wire 142 is connected to the second steering component 1128 . The first steering cable 141 and the second steering cable 142 are respectively installed in the two steering channels 124 of the guide tube 12 .

Further, the steering assembly 112 includes a steering base block 1121, a steering reel (not shown in the figure) and a steering knob 1123. The steering reel is rotatably installed on the steering base block 1121. The steering knob 1123 is connected to the steering reel, and at least a part of the steering knob 1123 extends to the outside of the guide body 111. Rotating the steering knob 1123 can drive the steering reel to rotate to control The steering cable 14 moves axially.

The steering assembly 112 further includes a steering link 1124, a knob gear 1125 and a gear plate 1126. The steering knob 1123 is installed on one end of the steering link 1124, and the knob gear 1125 is installed on an end of the steering link 1124. At the other end, the gear plate 1126 is connected to the steering reel, and the gear plate 1126 meshes with the knob gear 1125. Rotating the steering knob 1124 can drive the steering link 1124 and the knob. The gear 1125 rotates, and the knob gear 1125 drives the gear plate 1126 and the steering reel to rotate.

Further, the steering assembly 112 further includes a blocking member installed on the rotating wheel of the steering reel and a resistance member installed inside the steering base block 1121 , the blocking member abuts against the resistance member , to increase the resistance of turning the steering reel and improve the stability of the steering reel when no force is applied.

The steering base block 1121 has an installation channel 1120 at its preset position. The proximal end of the guide catheter 12 is installed in the installation channel 1120 . The proximal end of the steering cable 14 extends out of the proximal end of the guide catheter 12 . The end is connected to the steering reel.

Preferably, the steering knob 1123 and the gear plate 1126 are respectively located on both sides of the steering base block 1121 , and the two steering knobs 1123 of the two steering assemblies 112 are respectively located on the guide body 111 Different sides, thereby making full use of the space of the guide body 111, helping to reduce the volume of the guide body 111, and preventing mutual interference when turning the knob.

Referring to Figures 18 and 21, the guide handle 11 further includes a hemostatic valve 113 located at the proximal end of the guide body 111. The hemostatic valve 113 includes a valve cap 1131 and a pusher installed on the valve cap 1131. part 1132 and a flow blocking member 1133. The flow blocking member 1133 is installed on the proximal end of the guide body 111, the valve cap 1131 is installed on the proximal end of the guide body 111, and the pushing part 1132 resists Connected to the flow blocking member 1133, the guide channel 13 passes through the valve cap 1131, the pushing part 1132 and the blocking piece 1133. Pushing the pushing part 1132 toward the far end can squeeze the blocking member 1133. The flow member 1133 causes the flow blocking member 1133 to radially deform and block the guide channel 13 to achieve a sealing effect.

Further, a guide chuck 1111 is provided at the proximal end of the guide body 111 , the proximal end of the guide catheter 12 is fixed to the distal end of the guide chuck 1111 , and the hemostatic valve 113 The valve cap 1131 is rotatably mounted on the proximal end of the guide chuck 1111 . Preferably, the valve cap 1131 is threadedly connected to the proximal end of the guide chuck 1111, and rotating the valve cap 1131 relative to the guide chuck 1111 can control the axial movement of the valve cap 1131.

Furthermore, a guide flushing head 1112 is provided at the preset position of the guide chuck 1111 , and the guide flushing head 1112 is connected with the guide catheter 12 .

Referring to Figure 27, pulling the first steering pull wire 141 proximally can drive the distal end of the guide catheter 12 to move along the movement direction one or the movement direction three, controlling the distal end of the guide catheter 12 to approach the ring plane. to move in the direction; operating the first steering component 1127 controls the first steering wire 141 to move distally, and can control the distal end of the guide catheter 12 to move in the second direction of movement, and control the movement of the guide catheter 12 The distal end moves away from the plane of the ring. Operating the second steering component 1128 drives the second steering wire 142 to move axially, thereby controlling the distal end of the guide catheter 12 to be finely adjusted to one side.

Rotating the first knob 21225 can control the axial movement of the first bending wire 2431 and the second bending wire 2432 to control the distal end of the operating catheter 22 along the movement direction or the movement. Movement in direction five; rotating the second knob 21226 can control the axial movement of the third bending wire 2433 to control the movement of the distal end of the operating catheter 22 in the movement direction six.

Referring to Figure 27, operating the guiding handle 11 controls the distal end of the guiding catheter 12 to form a bend along the movement direction, so that the distal end of the guiding catheter 12 moves to a position above the annular plane (valve annulus position). position, at this time, the distal plane of the guide catheter 12 is roughly parallel to the annular plane; the guide handle 11 can also be operated to control the guide catheter 12 to move along the movement direction from this position until the guide The distal plane of the guide tube 12 is substantially perpendicular to the ring plane. At this time, the guide catheter 12 is in a substantially straight state, which is more conducive to the passage of the control catheter 22 and the clamping instrument 30, which can be called transportation. Position; operating the guide handle 11 controls the distal end of the guide catheter 12 to move along the movement direction and return to the positioning position above the ring plane. In the positioning position, a part of the control catheter 22 extends from the distal end of the guide catheter 12, and operating the operating handle 21 can control the movement of the distal end of the control catheter 22 along the movement directions four, five, and four. Movement in direction six, wherein movement direction four and movement direction five are approximately along the same axis x, movement direction six is approximately along axis y, and the plane where axis x and axis y are located is approximately the distal plane of the control catheter 22 . In the positioning position, operating the guide handle 11 can also control the distal end of the guide catheter 12 to move in an auxiliary direction. The auxiliary direction is configured to adjust the position of the distal end of the guide catheter 12 in a smaller manner. , to produce a position change in the auxiliary direction to the distal position of the control catheter 22 .

Referring to FIGS. 16 , 17 and 22 , the guide catheter 12 and the control catheter 22 are respectively three-layer catheters including an inner layer 121 , a middle layer 122 and an outer layer 123 . In the guide catheter 12 , the steering wire 14 is provided between the inner layer duct 121 and the middle layer duct 122 . In the control conduit 22 , the bending wire 243 is provided between the inner conduit 121 and the middle conduit 122 , and the wire channel 220 is formed in the space surrounded by the inner conduit 121 .

During the manufacturing process of the control conduit 22, a conduit forming the wire channel 220 is placed outside the conduit forming the control channel 25; then the inner conduit 121 is wrapped on the outside; A conduit for forming the bending channel 222 is provided on the outside, and the gap between the two forms the bending channel 220; the intermediate conduit 122 is wrapped on the outside of the conduit for forming the bending wire 243, and then The outside is covered with an outer conduit 123 . Preferably, the middle layer conduit 122 is a mesh structure. The manufacturing process of the guide catheter 12 is similar to the manufacturing process of the control catheter 22 and will not be described again.

Referring to Figures 23 and 24, the control conduit 223 forming the control channel 25 in the control conduit 22 is formed by a plurality of metal wires arranged in sequence. In some deformed embodiments, it can also be formed by a multi-layer metal wire stack. . Preferably, several metal wires forming the control channel 25 are arranged in spiral bends along the length direction, thereby increasing the overall structural strength.

Preferably, the outer diameter of the conduit forming the control channel 25 is the same as the outer diameter of the connecting column 26 and is connected to the proximal end of the connecting column 26 .

The delivery rod 23 is an elongated rod, and the delivery rod 23 is also formed by a plurality of metal wires that are arranged and surrounded in sequence. In some deformed embodiments, it can also be formed by a multi-layer metal wire stack. Preferably, the diameter of the distal end of the delivery rod 23 is smaller than the diameter of the proximal end.

Referring to Figure 25, in some variant embodiments, the delivery rod 23 is a segmented structure, including a distal section 2351, a proximal section 2352, and a section between the distal section 2351 and the proximal section 2352. Transition element 2353, the proximal section 2351 is formed by winding metal wire, the distal section is formed by spirally winding elastic wire, and the diameter of the distal section 2351 is smaller than the diameter of the proximal section 2352, which can effectively The stiffness of the distal end of the delivery rod 23 is reduced to reduce the impact of the delivery rod 23 on the clamping instrument 30 .

Referring to FIG. 28 , the adjustable delivery system further includes a bracket 40 , and the guide mechanism 10 and the control mechanism 20 are respectively installed on the bracket 40 . The bracket 40 includes a base 41, a first slider 42 and a second slider 43. The first slider 42 and the second slider 43 are respectively slidably installed on the base 41. The guide The mechanism 10 is installed on the first slide block 42 , and the control mechanism 20 is installed on the second slide block 20 .

The distal end of the guide body 111 of the guide handle 11 is provided with a first snap-in groove 1113, and the distal end of the body portion 212 of the control handle 21 is provided with a second snap-in slot 1114. The first engaging groove 1113 is adapted to engage with the first engaging portion on the first slider 42 , and the second engaging groove 1114 is adapted to engage with the second engaging portion on the second slider 43 . Snap-on part.

The bracket 40 also includes a first adjustment button 44 and a second adjustment button 45 installed on the base 41. The first adjustment button 44 is connected to the first slider 42, and the second adjustment button 45 is connected to the first slider 42. Regarding the second slider 43 , operating the first adjustment button 44 and the second adjustment button 45 can control the first slider 42 and the second slider 43 to move relative to the base 41 .

It should be noted that the above embodiments can be freely combined as needed. The above are only the preferred embodiments of the present invention. It should be pointed out that for those of ordinary skill in the art, several improvements and modifications can be made without departing from the principles of the present invention, and these improvements and modifications should also be regarded as protection scope of the present invention.

Claims (21)

1. The adjustable bend delivery system is characterized by including:

   The control mechanism includes a control handle, a control conduit and a bending cable. The proximal end of the control conduit is fixed to the control handle. The control mechanism also has a control channel that passes through the control handle and the control conduit; The bending cable is movably installed on the control conduit;

   The control handle includes a body part, the body part includes a body shell, a bending component installed on the body shell, and a control component installed on the body shell. The proximal end of the bending cable is connected to The distal end of the bending component is connected to the distal end of the control catheter;

   Also comprising a clamping instrument adapted to be mounted on the distal end of the manipulation catheter;

   The control mechanism also includes a control pull wire movably installed in the control channel. The proximal end of the control pull wire is connected to the control component, and the distal end is suitable for connection to the clamping instrument to operate the control The assembly controls the movement of the control cable to control the clamping device.
2. The adjustable bending delivery system according to claim 1, characterized in that the bending assembly includes a base block, a winding wheel and a knob, the base block has a receiving channel, and the proximal end of the control catheter is installed on the The accommodation channel, the reel is rotatably mounted on the base block and is located on one side of the accommodation channel, the knob is connected to the reel, and the proximal end of the bending cable is connected to The reel.
3. The adjustable bend delivery system according to claim 2, wherein the reel includes a first reel, a second reel and a third reel; the knob includes a first knob and a third reel. Two knobs; the first reel and the second reel are respectively rotatably installed on the base block and located on both sides of the accommodation channel, and the third reel is rotatably installed. On the base block, the first knob is connected to the first reel, and at least a portion of the first knob extends to the outside of the body housing, and the first reel is connected to the first reel. For the second reel, rotating the first knob can drive the first reel and the second reel to rotate in opposite directions, and the second knob is connected to the third reel;

   The bending cable includes a first bending cable, a second bending cable, and a third bending cable, and the proximal ends of the first bending cable, the second bending cable, and the third bending cable They are respectively connected to the first winding wheel, the second winding wheel and the third winding wheel, and the distal ends are respectively connected to different positions of the distal end of the control catheter.
4. The adjustable bending delivery system according to claim 3, wherein the distal ends of the first bending cable, the second bending cable and the third bending cable are arranged in a substantially triangular shape.
5. The adjustable-bending delivery system according to claim 4, wherein the straight line where the distal ends of the first bending cable and the second bending cable are located passes through the center of the control catheter.
6. The adjustable bending delivery system according to claim 3, wherein the bending assembly further includes a driving gear installed on the first reel and a driven gear installed on the second reel. , and the driving gear meshes with the driven gear.
7. The adjustable bending delivery system according to claim 3, wherein the bending assembly further includes a first knob column and a second knob column, one end of the first knob column is connected to the first knob, The other end is connected to the first reel; one end of the second knob post is connected to the second knob, and the other end is connected to the third reel; the first knob post and the third The two knob columns are respectively provided with blocking members, the base block is provided with a resistance member, and the blocking member is in contact with the resistance member.
8. The adjustable bend delivery system according to claim 1, characterized in that the control component includes a catching pull wire rod and a locking pull wire rod, the control pull wire includes a catching pull wire and a locking pull wire, the catching pull wire and the locking pull wire The distal ends of the locking pull wires are respectively connected to the clamping instruments, and the proximal ends of the catching pull wires and the locking pull wires are respectively connected to the catching pull wire rods and the locking pull wire rods; the body part has a pull wire cavity, the distal ends of the catching wire rod and the locking wire rod are respectively movably installed in the wire cavity of the body part.
9. The adjustable bend delivery system according to claim 8, characterized in that a set of first latches are provided on the upper and lower sides of the catching wire rod and/or the locking wire rod, and the inside of the wire cavity The upper and lower inner walls are respectively provided with a set of second latching teeth. When the first latching teeth are latched to the second latching teeth, the first latching teeth and the second latching teeth engage with each other to limit the position. The catching wire lever and/or the locking wire lever cannot move axially in the wire cavity; rotating the catching wire lever and/or the locking wire lever causes the first latch to engage with the The second latching teeth are staggered with each other, and the catching wire lever and/or the locking wire lever can move in the wire cavity.
10. The adjustable bend delivery system according to claim 8, characterized in that the distal end of the catching pull rod and/or the locking pull rod is threadedly connected to the pull wire chamber, and the catching pull rod and/or Or a sliding block is rotatably installed in the locking wire rod, and the proximal end of the catching wire and/or the locking wire is fixed to the sliding block.
11. The adjustable-bend delivery system according to claim 1, wherein the control handle further includes a base portion connected to the proximal end of the body portion;

    The control mechanism also includes a delivery rod movably installed in the control channel. The distal end of the delivery rod and the distal end of the control pull wire are respectively adapted to be connected to the clamping instrument for controlling the The clamping device described above;

    The base part includes a base shell and a delivery component installed on the base shell. The delivery component is connected to the proximal end of the delivery rod and is used to control the axial movement of the delivery rod.
12. The adjustable-bend delivery system according to claim 11, wherein the delivery assembly includes a delivery gear and a delivery knob, and the delivery gear and the delivery knob are respectively installed on the inner and outer sides of the base shell, so The proximal end of the delivery rod is located in the base shell, and a plurality of meshing teeth are provided at a preset position of the proximal end of the delivery rod, and the delivery gear meshes with the plurality of meshing teeth on the delivery rod and rotates the The delivery knob can drive the delivery gear to rotate, and the delivery gear can drive the delivery rod to move axially.
13. The adjustable-bend delivery system according to claim 11, wherein the delivery rod is formed by at least one layer of metal wires arranged and surrounded in sequence.
14. The adjustable delivery system of claim 11, wherein the delivery rod includes a distal section, a proximal section and a transition element between the distal section and the proximal section, The proximal section is formed by winding metal wire, the distal section is formed by spiral winding of elastic wire, and the diameter of the distal section is smaller than the diameter of the proximal section.
15. The adjustable delivery system according to any one of claims 1 to 14, further comprising a guiding mechanism including a guiding handle and a guiding catheter, the proximal end of the guiding catheter being fixed on the A guide handle, the guide mechanism also has a guide channel that passes through the guide handle and the guide catheter, the control catheter is adapted to be installed in the guide channel, and the distal end of the control catheter Suitable to pass through the guide channel.
16. The adjustable and bendable delivery system according to any one of claims 1 to 14, characterized in that the conduit forming the control channel is formed by at least one layer of metal wires arranged and surrounded in sequence.
17. The adjustable delivery system according to claim 16, wherein the guide handle includes a guide body and a steering assembly installed on the guide body, the guide mechanism further includes a steering pull wire, The proximal end of the steering cable is connected to the steering assembly, and the distal end of the steering cable is connected to the distal end of the guide catheter. Operating the steering assembly can drive the steering cable to move axially to adjust the guide tube. The angle of the distal end of the guide tube.
18. The adjustable-bend delivery system according to claim 11, wherein the control mechanism further includes a connecting post provided at the distal end of the control catheter;

    The clamping instrument includes a bracket, an attachment post, an anchoring arm, a clamping arm and an actuating rod. The distal end of the attachment post is fixed to the bracket, and the proximal end is detachably connected to the distal end of the connecting post. end, the anchor arm and the clamping arm are respectively rotatably installed on the bracket, the actuating rod is movably installed in the attachment column, and the distal end of the actuating rod is connected to the clamping arm, the proximal end of the actuating rod is detachably connected to the distal end of the delivery rod;

    The proximal end of the capture pull wire is connected to the control handle, and the distal end is connected to the anchor arm. Moving the capture pull wire can drive the anchor arm to rotate relative to the bracket.
19. The adjustable bend delivery system according to claim 18, characterized in that the clamping instrument further includes a locking mechanism, the locking mechanism includes a locking block and an elastic element, the locking block is rotatably installed on the bracket The distal end of the locking block has a locking end and a connecting end, and the elastic element is provided between the locking block and the bracket;

    The proximal end of the locking pull wire is connected to the control handle, and the distal end is connected to the connecting end of the locking block;

    In the locked state, the locking end is in contact with the distal end of the actuating rod; pulling the locking wire drives the locking block to rotate and compress the elastic element, and the locking end is separated from the actuating rod.
20. The adjustable bend delivery system according to claim 19, characterized in that the distal end of the stent has a locking groove, the locking block is rotatably installed in the locking groove, and the elastic element is installed in the locking groove. The locking groove is in contact with the locking block.
21. The adjustable and bendable delivery system according to claim 18, characterized in that the stent is a hollow structure and includes two opposite outer side walls, and an accommodation space is formed between the two opposite outer side walls, and the clamping arm is The connecting end has an inner hole and an outer hole. The connecting end of the clamping arm extends into the accommodation space of the bracket. The outer hole and the bracket are rotatably connected by a pin and can be rotated around the bracket. The pin rotates.

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