WO2023213455A1 - Tête de distribution pour liquides pharmaceutiques ou cosmétiques - Google Patents

Tête de distribution pour liquides pharmaceutiques ou cosmétiques Download PDF

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Publication number
WO2023213455A1
WO2023213455A1 PCT/EP2023/053250 EP2023053250W WO2023213455A1 WO 2023213455 A1 WO2023213455 A1 WO 2023213455A1 EP 2023053250 W EP2023053250 W EP 2023053250W WO 2023213455 A1 WO2023213455 A1 WO 2023213455A1
Authority
WO
WIPO (PCT)
Prior art keywords
discharge
spring
discharge head
valve
liquid
Prior art date
Application number
PCT/EP2023/053250
Other languages
German (de)
English (en)
Inventor
Stefan Ritsche
Jürgen Greiner-Perth
Original Assignee
Aptar Radolfzell Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptar Radolfzell Gmbh filed Critical Aptar Radolfzell Gmbh
Publication of WO2023213455A1 publication Critical patent/WO2023213455A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0062—Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/0064—Lift valves
    • B05B11/0067—Lift valves having a valve seat located downstream the valve element (take precedence)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/1055—Filters bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/1065—Filters in a path in the expiratory path
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1073—Springs
    • B05B11/1074—Springs located outside pump chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1073—Springs
    • B05B11/1077—Springs characterised by a particular shape or material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/586—Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7518—General characteristics of the apparatus with filters bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/06—Packaging for specific medical equipment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media

Definitions

  • the invention relates to a liquid dispenser and a dispensing head intended for this purpose for pharmaceutical or cosmetic liquids.
  • the discharge head has a base unit for attachment to a liquid reservoir and a discharge unit that can be moved relative to the base unit.
  • the discharge unit has a discharge opening through which liquid can be dispensed.
  • the discharge head has a pump device which can be actuated by depressing the discharge unit in the direction of the base unit and by means of which liquid can be discharged that was previously sucked from the liquid dispenser into a pump chamber of the pump device.
  • the discharge unit After depressing the discharge unit for the purpose of discharging the liquid, the discharge unit returns to its starting position in the course of a return movement, in which it is spaced from the base unit.
  • liquid is sucked from the liquid storage into the pump chamber, which is at least partially discharged the next time the discharge unit is depressed.
  • the discharge head has a return spring which is tensioned when the discharge unit is depressed and then causes the return movement.
  • Generic liquid dispensers are usually designed as disposable dispensers. After the liquid in the liquid storage has been used up, they are disposed of.
  • the object of the invention is to design a liquid dispenser of the type described above or its discharge head in such a way that a high degree of recyclability is achieved.
  • a discharge head for pharmaceutical or cosmetic liquids and an unfilled or filled liquid dispenser which comprises a liquid reservoir and a discharge head of the type mentioned.
  • the discharge head according to the invention comprises, in the manner described above, a base unit which is connected to the liquid reservoir, in particular by means of a screw or snap connection. A one-piece connection between the base unit and the liquid storage is also possible.
  • the discharge unit of the discharge head is displaceable, preferably linearly displaceable, in particular in a direction that corresponds to a central axis of the base unit and/or the liquid reservoir.
  • the force applied to the discharge unit relative to the base unit is done manually.
  • the user preferably grasps the base unit or the liquid storage and presses down the discharge unit using the index finger and/or middle finger.
  • the pump device is arranged between the base unit and the discharge unit in such a way that it is actuated by the relative displacement of the base unit and the discharge unit.
  • the pump device preferably has a pump chamber.
  • An inlet channel provided with an inlet valve connects the pump chamber with the liquid storage.
  • An outlet channel provided with an outlet valve connects the pump chamber with the discharge opening, which penetrates an applicator housing of the discharge unit.
  • the outlet valve closes and the inlet valve opens, so that the pump chamber, which enlarges, sucks in liquid from the liquid reservoir, preferably by means of a riser pipe which projects into the liquid reservoir, or from a collapsing bag within the liquid reservoir.
  • the discharge head according to the invention is preferably easily recyclable.
  • it can consist entirely or almost entirely (>99%) of plastic, preferably of plastics that can be processed in a common recycling process.
  • the return spring which acts between the base unit and the discharge unit, is also designed according to the invention as a plastic spring.
  • the return spring can be a bellows spring, i.e. a circumferentially closed bellows, which rests with its two ends on surfaces of the discharge unit and the base unit.
  • the bellows spring When the discharge unit is pressed down, the bellows spring is axially compressed and elastically tensioned. If the depressing force is no longer applied, the bellows spring relaxes and pushes the discharge unit away from the base unit again.
  • a preferred material for the bellows spring is TPE (thermoplastic elastomer).
  • the return spring is attached to an outside of the discharge unit and can therefore be seen during regular operation. This avoids the need to keep the interior space defined by the base unit and the discharge unit sufficiently large for a bellows spring in the relaxed and compressed state.
  • the plastic return spring is arranged in such a way that it envelops, at least in sections, outer surfaces of the base unit and the discharge unit. It is also considered advantageous in such a case if the discharge unit and the base unit have a spring receiving space in an interior jointly enclosed by these elements, which is designed to accommodate a coil spring, so that a metal coil spring is also used instead of the plastic return spring can be.
  • annular contact surfaces are provided for the coil spring on the base unit and the discharge unit, the annular contact surfaces preferably being flanked on the inside and/or outside by guide surfaces.
  • a variant is also conceivable in which both an internal metallic coil spring and an external plastic spring, in particular a bellows spring, are provided, so that an increased common spring force is achieved. If the plastic spring is provided on the outside of the discharge head, an upper side of the base unit preferably provides a force coupling surface.
  • the opposite force coupling surface on the side of the discharge unit is preferably formed by a finger rest.
  • This finger rest is provided on the discharge unit for the purpose of manually applying force to the discharge unit in the direction of the base unit.
  • it is preferably a finger rest with an annular shape that surrounds the applicator housing of the discharge unit.
  • the finger rest can in particular be of constant width all around or have two opposite actuating wings for supporting the index finger and middle finger.
  • the finger rest has a non-round shape on the outside.
  • the finger rest can have two support areas for two fingers on opposite sides of the applicator housing.
  • the return spring preferably acts on this finger rest and for this purpose lies in particular on an underside of the finger rest or is attached here.
  • the finger rest can be integrally formed on the applicator housing. In contrast, however, it is preferred if it is a separate component which is attached to the applicator housing, in particular by means of a snap connection. This allows different finger rests to be used for versions of the discharge head with and without an external plastic spring.
  • the finger rest can also be formed in one piece with the plastic spring.
  • a possible design provides that the part forming the finger rest and the part forming the plastic spring consist of a uniform, identical material, for example a TPE plastic. The material is primarily designed based on the desired deformation characteristics of the plastic spring.
  • the part forming the finger rest is preferably stiffened by a greater wall thickness than the spring part and/or by additional ribbing so that it tends to deform only to an acceptable extent.
  • a one-piece shape of the finger rest with the plastic spring can also be formed by a material connection of two different plastic materials.
  • a more rigid one Part forms at least part of the top of the finger rest, while a more elastic part forms the spring part of the one-piece component.
  • the rigid part can additionally be formed in one piece with the applicator housing, but can also be formed as a separate part.
  • the production of a cohesive connection is preferably carried out by multi-component injection molding, with first a first plastic being introduced into an expandable injection molding cavity and then, after the cavity has been enlarged, a second plastic being introduced. In a border zone, the plastics form an intimate and airtight connection.
  • the interface is shaped in such a way that the parts made of different plastics are also positively connected to one another by means of undercuts in addition to the material connection.
  • the one-piece design of the finger rest with the plastic spring simplifies assembly, since attaching the finger rest to the applicator housing also brings the spring into its desired position.
  • the same can also be achieved with a two-piece design, in which the finger rest and the plastic spring are separately manufactured parts that are already connected to one another in a force-fitting or positive manner before being attached to the applicator housing, for example by a clamp connection.
  • the finger rest and the return spring are designed as separate components, it is advantageous if a centering geometry is provided on the finger rest and in particular on its underside, which guides a force coupling surface of the return spring from the inside and / or outside and preferably also the force or positive coupling of the return spring and finger rest.
  • the finger rest and the return spring are designed as separate parts and the return spring is designed as a bellows spring, it is advantageous if the side of the bellows spring that rests against the finger rest has an outwardly or preferably inwardly acting collar, which increases the diameter of the bellows segments by at least 5%, preferably at least 10%, projects outwards or inwards. This collar makes demoulding easier when producing the bellows spring.
  • the finger rest mentioned can be the carrier of the return spring.
  • the return spring is firmly connected to this component, which acts as a carrier.
  • Both clamp connections and one-piece connections come into question here, in particular material-locking connections. in which the component acting as a carrier and the return spring are made of different materials, but are inextricably and intimately connected to one another by multi-component injection molding.
  • the return spring When the carrier is mounted, the return spring is also brought into its desired position. This makes it easier to install the return spring.
  • the return spring is not firmly mounted on components other than the carrier component, but only comes into contact with them during assembly or operation.
  • the pump device is designed and/or coupled to the discharge unit in such a way that, starting from the starting position, the discharge unit is displaced in the direction of the actuated end position for a partial stroke path no liquid discharge is caused.
  • the initial actuation does not initially lead to a discharge, preferably in that a backflow of liquid from the pump chamber into the liquid storage is initially possible.
  • the backflow is only closed after a short partial stroke, preferably after at least 3% of the total stroke, in particular after at least 6% of the total stroke. Only after this partial stroke has been covered is the pump chamber isolated and the discharge begins.
  • the discharge head preferably has an inlet valve which is designed as a slide valve.
  • This slide valve has a valve channel which is preferably provided in a stationary manner on the base unit and a valve slide which is preferably provided in a stationary manner on the discharge unit, which moves into the valve channel as intended during discharge and which is designed for circumferential sealing with an inside of the valve channel.
  • the delayed discharge described above and the consistently uniform dosage quantity can be achieved particularly well.
  • the pump chamber is isolated from the liquid reservoir in that intermediate position in which the valve slide comes into extensive contact in the valve channel.
  • the outlet valve of the discharge head preferably opens under pressure control, so that it opens in the event of excess pressure in the pump chamber.
  • the outlet valve is preferably designed as a “tip seal” valve, which seals directly at the discharge opening, so that it effectively prevents germs from entering the discharge head.
  • This “tip seal” valve is preferably the only exhaust valve.
  • the discharge head has a first outlet valve, which directly adjoins the pump chamber, and a second outlet valve downstream of the first outlet valve, which is designed as a “tip seal” valve in the manner described and directly at the discharge opening is arranged.
  • the preferably only one outlet valve has, as a pressure-dependent opening valve, a valve body which is pressed into a closed position by a valve spring.
  • This valve spring is preferably designed as a plastic spring to enable uniform recycling of the discharge head.
  • the valve spring can also be designed as a bellows spring.
  • the valve spring of the exhaust valve does not require a large spring travel, other designs are considered advantageous, in particular a design in which the valve spring is formed by a spring tubular body, which allows elastic axial shortening by means of openings penetrating the tubular body.
  • the openings are preferably designed in the form of slots introduced transversely to the compression direction.
  • the outlet valve is preferably designed in such a way that a pressure maximum is required at the beginning of an opening movement for the purpose of opening, wherein after opening the outlet valve can be kept open with a liquid pressure that is reduced compared to the pressure maximum.
  • the outlet valve is therefore preferably structurally designed so that it initially does not open when the pressure increases. In this phase, a pressure level that would be able to keep the valve open after opening is not sufficient to open the valve.
  • This behavior is preferably achieved in that the valve body and a contact surface of the discharge unit rest against each other in the closed state of the outlet valve and counteract the opening by the static friction prevailing between them. Only when a sufficiently high pressure is achieved is the static friction overcome and the exhaust valve opens suddenly. This opening characteristic prevents the valve from initially opening only a narrow outlet slot, which impairs the discharge characteristics.
  • the valve spring and the valve body of the outlet valve are preferably formed by a one-piece plastic part in order to achieve the assembly of the discharge head.
  • they preferably consist of a polyolefin plastic, in particular polyethylene.
  • a ventilation opening is preferably provided in the bellows spring, which has a clear cross section of at least 1 mm 2 , particularly preferably of at least 5 mm 2 .
  • the bellows spring can be a recess at the end of the bellows body.
  • the return spring surrounds an air spring space, within which air is contained, which is compressed when the discharge unit is moved to the base unit becomes. This air then acts as an additional return spring.
  • the ventilation path can be formed at least in sections by a capillary channel, which can be provided upstream or downstream of the ventilation chamber. If the capillary channel is provided upstream of the ventilation chamber in relation to an inflow direction, the capillary channel is preferably at least partially delimited by the bellows spring.
  • Said ventilation channel can additionally have a filter unit, which is preferably provided downstream of the ventilation chamber in relation to the inflow direction of the air and which prevents or reduces the penetration of germs.
  • the discharge head is intended as a discharge head for nasal application.
  • the applicator housing has an elongated shape that tapers towards a distal end, at least in a distal region.
  • a finger rest is preferably provided on the side of the applicator housing, in particular a circumferential finger rest or a finger rest with two wings for supporting the index finger and the middle finger, as already described above.
  • a discharge direction of the discharge opening is preferably aligned parallel to the direction of displacement of the discharge unit relative to the base unit.
  • Another preferred design is intended in particular for the topical application of liquids.
  • Such a discharge head can have a laterally arranged discharge opening.
  • a discharge direction of the discharge opening includes an angle > 0° with the direction of displacement of the discharge unit relative to the base unit, preferably an angle between 5° and 100°, in particular an angle between 30° and 60° or between 80° and 100°.
  • the discharge unit is preferably pressed down via an actuation surface provided on an upper side of the discharge head.
  • the discharge opening is provided on a laterally projecting nozzle which protrudes outwards beyond the outer contour of the bellows spring.
  • the discharge head and in particular its discharge opening can be designed for different forms of application.
  • the discharge head is preferably designed to emit a spray jet.
  • it can have a swirl chamber through which the emerging liquid is provided with a swirl before it exits, which leads to a conical spray jet when it exits.
  • the discharge head can also have a plurality of fine nozzle openings for generating a spray jet, in particular a nozzle plate in which these nozzle openings are provided.
  • the design as a drop dispenser with a drop formation surface downstream of the discharge opening for dispensing discrete individual drops and the design as a dispenser for dispensing an unatomized jet are also possible.
  • the discharge head and the overall dispenser are preferably designed in such a way that they allow easy recycling.
  • the discharge head or the liquid dispenser preferably consists of at least 90%, preferably at least 95%, particularly preferably 99% of polyolefin plastics.
  • the dispenser can consist predominantly or almost entirely of polyethylene.
  • the liquid dispenser according to the invention has a discharge head of the type described and a liquid reservoir which is connected to the base unit in a detachable or fixed manner, possibly even in one piece.
  • the liquid storage is preferably made of HDPE.
  • the liquid dispenser is usually delivered by the manufacturer with an empty liquid reservoir to a filling company, which fills it with liquid, especially a pharmaceutical one or cosmetic liquid.
  • a pharmaceutical liquid this is preferably intended for nasal application, oral application or topical application.
  • a pharmaceutical liquid is filled into the liquid dispenser, which also includes, in particular, saline aqueous solutions for application into the respiratory tract of a patient.
  • Aqueous solutions in the form of a Ringer's solution are also included, as are buffered solutions or aqueous solutions with at least one of the additives carbohydrates, essential oils, menthol and plant extracts as well as aqueous solutions containing vitamins, trace elements, manganese or zinc, or cinnamon oil, tea tree oil, sage oil, thyme oil , lemon balm oil.
  • the pharmaceutical liquid can also be a nasally administered liquid with a decongestant effect, in particular a liquid with an imidazoline component, such as oxymetazoline.
  • the invention also relates to a method for producing two types of dispensing heads.
  • the purpose of the process is to be able to produce both types of discharge heads particularly cheaply by using many identical parts.
  • the first type of discharge heads have an external bellows spring as a return spring. These are preferably discharge heads of the type described above.
  • the discharge heads of the second type do not have an external bellows spring made of plastic, but rather an internal coil spring, in particular a metallic coil spring. In the first type, such a coil spring is not provided.
  • the discharge heads of both types have an identical base unit for attachment to a liquid reservoir and an identical applicator housing, which can be moved as part of a discharge unit relative to the base unit and is penetrated by a discharge opening.
  • the dispensing unit and the base unit of both types of dispensing heads differ, apart from the spring used, from a maximum of different finger rests, while all other components are identical.
  • the base unit and the applicator housing together surround a spring receiving space, i.e. a space into which the metallic coil spring with, in particular, preferably cylindrical shear basic shape is recorded in the case of the discharge head of the second type.
  • the spring receiving space is preferably delimited at the end by annular contact surfaces on the base unit and the discharge unit, the contact surfaces preferably being flanked on the inside and/or outside by guide surfaces in order to hold the coil spring in position.
  • This spring receiving space is also provided for discharge heads of the first type. However, it remains empty because the reset is caused by the external bellows spring.
  • a metallic coil spring is only used in discharge heads of the second type.
  • the external plastic spring is attached instead, preferably by attaching a finger rest to which the bellows spring has already been previously attached or to which the bellows spring is attached in one piece.
  • 1 to 5 and 6A show a first exemplary embodiment of a liquid dispenser according to the invention or its discharge head.
  • FIGS. 1 to 6A show structural alternatives to the design of FIGS. 1 to 6A.
  • FIG. 7 to 9B show a second embodiment of a liquid dispenser according to the invention or its discharge head.
  • Fig. 10 illustrates how different types of discharge heads are produced based on largely identical components.
  • FIGS. 1 and 2 show the first exemplary embodiment of a liquid dispenser 10 according to the invention in a cut and uncut view.
  • 3A to 5 show the discharge head 20 of this liquid dispenser 10, with the unactuated and actuated states being shown in Figs. 3A and 3B.
  • the liquid dispenser 10 has a liquid storage 12 in the form of a plastic bottle made of HDPE and the discharge head 20 attached to the bottle neck of the liquid dispenser.
  • the discharge head 20 in turn has two main components that can be moved relative to one another along a pumping direction 2, namely a base unit 40 which is on the bottle neck of the liquid storage 12 is attached, as well as via a discharge unit 60, which is connected along the pumping direction 2 relative to the base unit 40.
  • a discharge opening 62 is provided through which liquid can be dispensed from the liquid storage 12.
  • the discharge head 20 has a pump device 50.
  • This pump device 50 has a pump chamber 51, which is connected via an inlet channel to an inlet valve 52 and to a riser pipe 19, which projects into the liquid reservoir 12.
  • the pump chamber 51 extends to an outlet valve 55, which is immediately upstream of the discharge opening 62.
  • the inlet valve 52 is designed as a slide valve. It has a stepped valve channel 53 on the base unit 40 side and a valve slide 54 retracting into it on the discharge unit 60 side. If the discharge unit 60 is depressed, as illustrated by the transition from FIG . From this point on, no liquid can get back into the liquid storage 12 from the pump chamber 51, so that the continued depression of the discharge unit 60 causes a pressure increase in the insulated pump chamber 51.
  • the outlet valve 55 is designed as a tip-seal valve. This means that it closes immediately before the discharge opening 62. It has a valve body 57 and a valve spring 56, wherein the valve body 57 and the valve spring 56 are designed as a one-piece component and are inserted with the end of the valve spring 56 into a recess of an internal component 61 of the discharge unit 60.
  • the valve spring 56 is formed by a spring tube body in which horizontal slots are provided to enable axial compression.
  • the valve body 57 projects through a vortex chamber to the discharge opening 62 and closes it in a resting state.
  • An increase in pressure in the pump chamber 51 causes the valve body 57 to be subjected to downward force, which is suitable for displacing the valve body 57 so that the outlet valve 55 is opened and liquid can escape through the discharge opening 62.
  • the liquid emerges in the form of a spray jet through the swirl chamber upstream of the discharge opening 62.
  • the one-piece component which forms the valve body 57 and the valve spring 56, is guided on its outside by a sliding edge 61A of the inner component 61.
  • this sliding edge 61A causes static friction, which means that when the pressure increases, the outlet valve 55 does not open immediately, but rather with a slight delay and then suddenly. This ensures that during discharge the valve body 57 is spaced far enough away from the discharge opening 62 to achieve proper discharge.
  • the discharge unit 60 is pressed down via a finger rest 68, which in the exemplary embodiment of FIGS. 1 to 5 is attached to the outside of the applicator housing 64 by means of a snap connection.
  • the user usually places his index finger and his middle finger on this finger rest 68 in order to use it to press down the discharge unit 60 relative to the base unit 40.
  • the discharge unit 60 returns to its starting position shown in FIG. 3A. This occurs under the action of a plastic return spring 80, which is designed in the manner of a bellows. This plastic return spring 80 is provided on the outside of the discharge head 20 and encloses the upper end of the base unit 40 and the lower end of the discharge unit 60.
  • the design of the discharge head with a plastic return spring 80 allows the entire discharge head 20 to be made of plastic. Since both the plastic return spring 80 and the valve spring 56 are made of plastic, the use of metallic coil springs can be dispensed with. Preferably, all components or, based on the mass, at least 90% of the discharge head 20 are made from polyolefin plastics, in particular from different types of polyethylene.
  • the dispensing head 20 has a spring receiving space 90 which is intended to accommodate a metallic coil spring, but is free of such a metallic return spring in the configuration of the dispenser according to Figs. 1 to 5.
  • this spring receiving space 90 allows, using many identical parts, to provide a discharge head 20 similar to the one described here, which does not have an external plastic return spring 80, but instead has an internal metallic coil spring. This will also be shown below.
  • a plastic restoring spring 80 offers considerable advantages with regard to recycling, this usually does not guarantee the same strong and relaxation-free restoring by a metal coil spring. The choice of design of the pumping device 50 takes this into account.
  • valve slide 54 Since the already described valve slide 54 must first be moved down a few millimeters during the actuation before it closes the inlet valve 52, in a dispenser of the type shown it is not very important that the plastic return spring 80 actually controls the dispensing unit 60 presses into the uppermost end position of FIG. 3A. Even if a plastic return spring 80, which is partially relaxed, for example due to a long storage period, is used, this is usually sufficient to push the valve slide 54 together with the discharge unit 60 so far upwards that the valve slide 54 is pulled out of the tapered part of the valve channel 53. This is sufficient for the pump device 50 to function properly.
  • FIG 3B illustrates that when the discharge unit 60 is depressed, the valve slide 54 leaves the tapered part of the valve channel 53 in its end position, so that at this moment the excess pressure in the pump chamber 51 is suddenly reduced and the discharge ends.
  • the discharge quantity of the pump device 50 is determined solely by the length of the tapered part of the valve channel 53.
  • the ventilation path 18 is shown in FIG. 4.
  • the ventilation path initially runs from the outside to the inside through a gap that the plastic return spring 80, designed as a bellows spring, forms with the housing of the base unit 40.
  • the ventilation path 18 continues through a guide of the discharge unit 60 and the base unit 40 into a capillary channel 16, which is formed by the base body of the base unit 40 and a sleeve pushed onto it, up to a filter unit 15 in which incoming air is freed from bacteria becomes.
  • the ventilation path 18 runs through a ventilation chamber 14, which is delimited on the outside by the plastic return spring 80 designed as a bellows spring.
  • the air flows in through a gap at the lower end of the plastic return spring 80. This is a very narrow gap, so that the air humidified by the liquid in the liquid reservoir 12 is only in one in the ventilation chamber 14 can escape into the environment to a small extent.
  • Fig. 5 shows the discharge head 20 again, whereby it is made clear here that the discharge head 20 as a whole can already be assembled when the plastic return spring 80 and the finger rest 68 are finally assembled.
  • 6A to 6D show different designs of the finger rest 68 and the plastic return spring 80.
  • Fig. 6A shows the version already shown in the previous figures.
  • the finger rest 68 and the plastic return spring 80 are realized as a one-piece component, which is manufactured by two-component injection molding. This means that during assembly the bellows spring can be handled indirectly via the finger rest 68 and attached to the base unit 40 and the discharge unit 60.
  • the plastic return spring 80 and the finger rest 68 form separate components.
  • the plastic return spring 80 has at its upper end an inwardly facing circumferential collar 80A, which has a reduced inner diameter compared to the folds of the bellows.
  • Such a collar 80A helps demold the bellows during manufacture.
  • the finger rest 68 is provided with a circumferential centering edge 68A, which ensures the positional stability of the plastic return spring 80.
  • the collar 80A points inward up to the applicator housing 64 and thus independently effects centering, such additional centering is not absolutely necessary.
  • Fig. 6C shows a design in which the bellows is formed in one piece with the finger rest 68 as in Fig. 6A.
  • the special feature here is that the finger rest 68 is designed in one piece with the applicator housing 64. This means that during assembly, by attaching the discharge unit 60 to the base unit 40, the finger rest 68 and the plastic return spring 80 are also assembled.
  • Fig. 6D The design of Fig. 6D is similar to that of Fig. 6B.
  • the bellows is designed as a separate component.
  • the finger rest 68 has a centering ring ng68A, which in this case centers the plastic return spring 80 from the inside.
  • 7 to 9B show a different type of liquid dispenser 10, which differs from the design of FIGS. 1 to 6 in its basic shape.
  • 7 and 8 show the liquid dispenser 10 in a cut and uncut view.
  • 3A and 3B show the discharge head 20 of this liquid dispenser 10 in the unactuated and actuated states.
  • the liquid dispenser 10 shown here is intended for topical use. Its purpose is to apply liquid to a patient's skin.
  • the discharge opening 62 is also provided on the side of the discharge head 20 in this design.
  • the discharge direction includes an angle of 90° with an actuation direction 2 in which the discharge unit 60 can be moved relative to the base unit 40.
  • the pump chamber and the inlet valve are largely identical to the design of FIGS. 1 to 6, in this design the outlet valve 55, like the discharge opening 62, is provided laterally.
  • the sealing between the valve body 57 and the discharge unit 60 is carried out by sealing lips 58 which are provided on the valve body 57.
  • the valve body 57 and the valve spring 56 are arranged in a receiving space which is closed by a closure part 64A of the applicator housing 64.
  • the actuation takes place by means of an actuation surface 70 provided on the top of the discharge unit 60.
  • 10 makes it clear again how the discharge head 20 shown, in particular that of FIGS. 1 to 5, can be the basis for a product range with different discharge heads.
  • 10 shows in the upper half of the figure the two relevant sub-units of the discharge head 20, the base unit 40 and the discharge unit 60, the discharge unit 60 not yet being provided with a finger rest 68.
  • These two subunits 40, 60 are identical for two designs of the discharge head 20, namely for the variant shown on the left in the figure with an internal metallic coil spring as a return spring 180 and for the variant on the right in FIG. 10, which is that of FIGS. 1 to 5 corresponds.
  • FIG. 11 and 12 show two designs of a liquid dispenser, which essentially correspond to that of FIGS. 1 to 6 in terms of their internal construction.
  • the special feature here lies in the shape of the finger rest 68.
  • the finger rest 68 does not have a round outer contour, but rather an approximately elliptical outer contour r68B.
  • Two support surfaces 69A on both sides of the applicator 64 point outwards and protrude beyond the liquid reservoir 12 in the radial direction. They serve to support two fingers, in particular the index finger and middle finger. Connecting pieces 69B that project less radially are provided between the actuating surfaces 69A, these connecting pieces 69B being optional in the case of the design of FIG. 12.
  • FIGS. 11 and 12 with the two wing-like actuation surfaces 69A results in the liquid dispenser as a whole losing its ability to roll. This can simplify the recycling process because the liquid dispensers cannot fall off conveyor belts and, in particular, can be reproducibly removed from a conveyor belt using targeted air blasts. With rollable liquid dispensers, however, such handling is more difficult.
  • FIGS. 11 and 12 differ from one another in that in the case of the design of FIG. 11, the finger rest 68 is formed by a component that is separate from the applicator 68, preferably by a component that is formed in one piece with the spring 80. In the design of FIG. 12, however, a one-piece connection between applicator 68 and finger rest 68 is provided, similar to FIG. 6C.

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Abstract

L'invention concerne une tête de distribution (20) pour des liquides pharmaceutiques ou cosmétiques, comprenant une unité de base (40) destinée à être fixée à un réservoir de liquide (12) et comprenant une unité de distribution (60), qui comporte un logement d'applicateur (64) dans lequel pénètre une ouverture de distribution (62). L'unité de distribution (60) est déplaçable par rapport à l'unité de base (40) à l'encontre de la force d'un ressort de rappel (80), un dispositif de pompage (50) de la tête de distribution (20) pouvant être actionné par le mouvement de l'unité de distribution (60) par rapport à l'unité de base (40) et, en réponse à l'actionnement, amenant du liquide provenant du réservoir de liquide (12) à l'ouverture de distribution (62). Le ressort de rappel (80) est conçu sous forme d'un ressort en matière plastique, de préférence sous forme d'un ressort à soufflet en matière plastique.
PCT/EP2023/053250 2022-05-03 2023-02-09 Tête de distribution pour liquides pharmaceutiques ou cosmétiques WO2023213455A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22171432.2 2022-05-03
EP22171432.2A EP4272872A1 (fr) 2022-05-03 2022-05-03 Tête de distribution pour liquides pharmaceutiques ou cosmétiques

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WO2023213455A1 true WO2023213455A1 (fr) 2023-11-09

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824672A (en) * 1956-03-09 1958-02-25 Jacob A Wersching Liquid dispensing pump
EP0250965B1 (fr) * 1986-06-21 1990-08-29 MegaPlast Dosiersysteme GmbH & Co. Distributeur
US5673824A (en) * 1995-05-31 1997-10-07 Taplast Srl Plastic dosing pump for dispensing liquids from containers
US20030075567A1 (en) * 2000-05-26 2003-04-24 Stefano Santagiuliana Bellows pump for delivery of liquids
US6672486B2 (en) * 2000-04-13 2004-01-06 Taplast Spa Multidose delivery pump
US20050165368A1 (en) * 2003-11-14 2005-07-28 Daniel Py Delivery device and method of delivery
WO2006122983A1 (fr) * 2005-05-19 2006-11-23 Bentfield Europe B.V. Pompe de distribution d'un produit fluide et distributeur
US7246723B2 (en) * 2001-06-13 2007-07-24 Taplast Spa Bellows pump for delivery of gas-liquid mixtures

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824672A (en) * 1956-03-09 1958-02-25 Jacob A Wersching Liquid dispensing pump
EP0250965B1 (fr) * 1986-06-21 1990-08-29 MegaPlast Dosiersysteme GmbH & Co. Distributeur
US5673824A (en) * 1995-05-31 1997-10-07 Taplast Srl Plastic dosing pump for dispensing liquids from containers
US6672486B2 (en) * 2000-04-13 2004-01-06 Taplast Spa Multidose delivery pump
US20030075567A1 (en) * 2000-05-26 2003-04-24 Stefano Santagiuliana Bellows pump for delivery of liquids
US7246723B2 (en) * 2001-06-13 2007-07-24 Taplast Spa Bellows pump for delivery of gas-liquid mixtures
US20050165368A1 (en) * 2003-11-14 2005-07-28 Daniel Py Delivery device and method of delivery
WO2006122983A1 (fr) * 2005-05-19 2006-11-23 Bentfield Europe B.V. Pompe de distribution d'un produit fluide et distributeur

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