WO2023207752A1 - Surgical robot and control system therefor - Google Patents

Surgical robot and control system therefor Download PDF

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WO2023207752A1
WO2023207752A1 PCT/CN2023/089533 CN2023089533W WO2023207752A1 WO 2023207752 A1 WO2023207752 A1 WO 2023207752A1 CN 2023089533 W CN2023089533 W CN 2023089533W WO 2023207752 A1 WO2023207752 A1 WO 2023207752A1
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electrode lead
target
image data
patient
electrode
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唐建东
周国新
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苏州景昱医疗器械有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/30Surgical robots
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0534Electrodes for deep brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062Spinal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36064Epilepsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067Movement disorders, e.g. tremor or Parkinson disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046Tracking techniques
    • A61B2034/2065Tracking using image or pattern recognition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/30Surgical robots
    • A61B2034/302Surgical robots specifically adapted for manipulations within body cavities, e.g. within abdominal or thoracic cavities

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Neurosurgery (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Robotics (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
  • Electrotherapy Devices (AREA)
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Abstract

Provided are a surgical robot and a control system therefor. The surgical robot (100) comprises a driving assembly (120) and a control assembly (110). The control assembly (110) is configured to: acquire a first image data of a patient by using an image acquisition device (S1); on the basis of the first image data, control the driving assembly (120) to implant an electrode cable into the cranium of the patient (S2); acquire a second image data of the patient by using the image acquisition device (S3); on the basis of the first image data and the second image data, detect whether a target point corresponding to the electrode cable is offset (S4); in the case that the target point corresponding to the electrode cable is detected to be offset, control the driving assembly (120) to adjust the pose of the electrode cable, such that the pose of the electrode cable is matched with the target point corresponding to the electrode cable (S5).

Description

手术机器人和手术机器人的控制系统Surgical robots and control systems for surgical robots
本申请要求在2022年04月27日提交中国专利局、申请号为202210454471.4的中国专利申请的优先权,该申请的全部内容通过引用结合在本申请中。This application claims priority to the Chinese patent application with application number 202210454471.4, which was submitted to the China Patent Office on April 27, 2022. The entire content of this application is incorporated into this application by reference.
技术领域Technical field
本申请涉及脑深部电刺激治疗的技术领域,例如涉及手术机器人和手术机器人的控制系统。The present application relates to the technical field of deep brain stimulation therapy, for example, to surgical robots and surgical robot control systems.
背景技术Background technique
在电极植入手术过程中,首先通过三维立体定位装置确定病人脑部的靶点位置,然后根据靶点位置在颅骨寻找合适的部位钻孔并切开脑膜,再将电极导线通过骨孔和脑膜缺口插入到相应的靶点位置。其中,最关键的步骤就是如何精准地将电极导线植入到最有效的靶点处。During the electrode implantation surgery, the target position of the patient's brain is first determined through a three-dimensional stereotaxic device, and then a suitable part of the skull is drilled according to the target position and the meninges are incised, and then the electrode leads are passed through the bone holes and meninges. The notch is inserted into the corresponding target position. Among them, the most critical step is how to accurately implant the electrode leads at the most effective target point.
一般而言,帕金森病常见的靶点为丘脑底核,其体积为4×5×6mm,大小和一粒黄豆差不多,而电极导线的直径只有1.27mm,最多3个电极触点能够位于丘脑底核中,因此,需要医生极其精准的定位靶点和电极导线,不然很有可能位置差之分毫,效果失之千里。Generally speaking, the common target of Parkinson's disease is the subthalamic nucleus, which has a volume of 4×5×6mm and is about the same size as a soybean. The diameter of the electrode lead is only 1.27mm, and up to three electrode contacts can be located in the thalamus. In the base nucleus, therefore, doctors need to locate the target and electrode leads extremely accurately, otherwise the position may be slightly different and the effect will be lost.
在将电极导线植入对应的靶点时,由于电极导线与大脑之间的作用力,脑组织发生形变,导致靶点位置发生偏移,使得电极导线的刺激部位偏离对应的靶点的位置,进而影响电极导线的植入效果。When the electrode lead is implanted into the corresponding target point, due to the force between the electrode lead and the brain, the brain tissue deforms, causing the target position to shift, causing the stimulation site of the electrode lead to deviate from the position of the corresponding target point. This in turn affects the implantation effect of the electrode leads.
专利CN113797440A公开了基于影像和电生理实时定位的脑深部电极自动植入系统,包括:控制中心、颅骨穿刺单元、电生理信号采集单元以及机械传送单元;颅骨穿刺单元被配置成实施穿刺操作;电生理信号采集单元被配置成采集脑深部电生理信号;机械传送单元被配置成带动颅骨穿刺单元;控制中心被配置成根据脑部三维立体影像生成影像靶点和虚拟植入通路,以及得到最佳植入点和植入深度,以及控制机械传送单元的动作。这种方式没有考虑将电极导线植入颅脑后,对应的靶点可能会发生偏移的情况,无法保障电极导线的植入效果。Patent CN113797440A discloses an automatic deep brain electrode implantation system based on imaging and electrophysiological real-time positioning, including: a control center, a skull puncture unit, an electrophysiological signal acquisition unit and a mechanical transmission unit; the skull puncture unit is configured to perform puncture operations; The physiological signal acquisition unit is configured to collect deep brain electrophysiological signals; the mechanical transmission unit is configured to drive the skull puncture unit; the control center is configured to generate image targets and virtual implantation pathways based on the three-dimensional brain image, and obtain the best implantation point and implantation depth, as well as controlling the action of the mechanical delivery unit. This method does not consider that the corresponding target point may shift after the electrode leads are implanted in the brain, and the implantation effect of the electrode leads cannot be guaranteed.
专利CN112842531A公开了一种神经外科手术计划系统,该系统包括:三维模型重建模块、弥散张量成像(Diffusion Tensor Imaging,DTI)模块、功能磁共振(functional Magnetic Resonance Imaging,fMRI)模块、影像配准模块、手术路径规划模块以及自动血管规避模块。这种方式也没有考虑将电极导线植 入颅脑后,对应的靶点可能会发生偏移的情况,无法保障电极导线的植入效果。Patent CN112842531A discloses a neurosurgery planning system, which includes: a three-dimensional model reconstruction module, a diffusion tensor imaging (DTI) module, a functional magnetic resonance (functional Magnetic Resonance Imaging, fMRI) module, and image registration module, surgical path planning module, and automatic blood vessel avoidance module. This method also does not consider implanting the electrode leads After entering the brain, the corresponding target point may shift, making it impossible to ensure the implantation effect of the electrode lead.
发明内容Contents of the invention
本申请提供一种手术机器人和手术机器人的控制系统,确保电极导线在植入颅内后,电极导线的位置与对应的靶点匹配,保障电极导线的植入效果。This application provides a surgical robot and a control system for the surgical robot to ensure that after the electrode lead is implanted in the skull, the position of the electrode lead matches the corresponding target point to ensure the implantation effect of the electrode lead.
本申请提供了一种手术机器人,所述手术机器人被配置成将至少两个电极导线植入患者颅内,所述手术机器人包括驱动组件以及控制组件;The present application provides a surgical robot, which is configured to implant at least two electrode leads into a patient's skull, and the surgical robot includes a driving component and a control component;
针对未植入的每个电极导线,所述控制组件被配置成执行如下步骤:For each electrode lead that is not implanted, the control component is configured to perform the following steps:
利用影像采集设备获取所述患者的第一影像数据;Using an image acquisition device to obtain the first image data of the patient;
基于所述第一影像数据,控制所述驱动组件将所述电极导线植入所述患者的颅内;Based on the first image data, control the driving component to implant the electrode lead into the patient's skull;
利用所述影像采集设备获取所述患者的第二影像数据;Using the image acquisition device to obtain second image data of the patient;
基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移;Based on the first image data and the second image data, detect whether the target target corresponding to the electrode lead is offset;
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配。When it is detected that the target point corresponding to the electrode lead is offset, the driving assembly is controlled to adjust the posture of the electrode lead so that the posture of the electrode lead is consistent with the position corresponding to the electrode lead. Target target matches.
在一些可选的实施例中,所述控制组件被配置成采用如下方式基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移:In some optional embodiments, the control component is configured to detect whether the target target corresponding to the electrode lead has shifted based on the first image data and the second image data in the following manner:
获取每个目标靶点在所述第一影像数据中的第一边界框位置信息;Obtain the first bounding box position information of each target target in the first image data;
获取每个目标靶点在所述第二影像数据中的第二边界框位置信息;Obtain the second bounding box position information of each target target in the second image data;
基于每个目标靶点对应的第一边界框位置信息和第二边界框位置信息,检测所述电极导线对应的目标靶点是否发生偏移。Based on the first bounding box position information and the second bounding box position information corresponding to each target target point, it is detected whether the target target point corresponding to the electrode lead is offset.
在一些可选的实施例中,所述控制组件被配置成采用如下方式检测所述电极导线对应的目标靶点是否发生偏移:In some optional embodiments, the control component is configured to detect whether the target target corresponding to the electrode lead has shifted in the following manner:
利用文本相似度模型对每个目标靶点对应的第一边界框位置信息和第二边界框位置信息进行相似度计算,得到每个目标靶点对应的位置相似度;Use the text similarity model to calculate the similarity of the first bounding box position information and the second bounding box position information corresponding to each target target, and obtain the position similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的位置相似度小于第一相似度阈值时,确定所述电极导线对应的目标靶点发生偏移。When the position similarity corresponding to the target point corresponding to the electrode lead is less than the first similarity threshold, it is determined that the target target point corresponding to the electrode lead has shifted.
在一些可选的实施例中,所述控制组件被配置成采用如下方式检测所述电 极导线对应的目标靶点是否发生偏移:In some optional embodiments, the control component is configured to detect the electrical Whether the target point corresponding to the polar wire has shifted:
基于每个目标靶点对应的第一边界框位置信息,从所述第一影像数据中截取得到每个目标靶点对应的预设区域的第一子图像;Based on the first bounding box position information corresponding to each target target point, intercept the first sub-image of the preset area corresponding to each target target point from the first image data;
基于每个目标靶点对应的第二边界框位置信息,从所述第二影像数据中截取得到每个目标靶点对应的预设区域的第二子图像;Based on the second bounding box position information corresponding to each target target point, intercept the second sub-image of the preset area corresponding to each target target point from the second image data;
利用图像相似度模型对每个目标靶点对应的第一子图像和第二子图像进行相似度计算,得到每个目标靶点对应的图像相似度;Use the image similarity model to calculate the similarity of the first sub-image and the second sub-image corresponding to each target target, and obtain the image similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的图像相似度小于第二相似度阈值时,确定所述电极导线对应的目标靶点发生偏移。When the image similarity corresponding to the target point corresponding to the electrode lead is less than the second similarity threshold, it is determined that the target target point corresponding to the electrode lead is shifted.
在一些可选的实施例中,所述控制组件被配置成采用如下方式当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配:In some optional embodiments, the control component is configured to control the driving component to position the electrode wire in the following manner when it is detected that the target point corresponding to the electrode wire has shifted. Adjust so that the posture of the electrode lead matches the target target corresponding to the electrode lead:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件将所述电极导线向下深入或者向上提取,以使所述电极导线的位姿与其所对应的目标靶点相匹配。When it is detected that the target point corresponding to the electrode lead is offset, the driving assembly is controlled to deepen the electrode lead downward or extract it upward, so that the posture of the electrode lead is consistent with the corresponding target point. match.
在一些可选的实施例中,所述控制组件被配置成采用如下方式当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配:In some optional embodiments, the control component is configured to control the driving component to position the electrode wire in the following manner when it is detected that the target point corresponding to the electrode wire has shifted. Adjust so that the posture of the electrode lead matches the target target corresponding to the electrode lead:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件将所述电极导线从所述患者的颅内移除,重新执行利用影像采集设备获取所述患者的第一影像数据的步骤,以控制所述驱动组件对所述电极导线进行位姿的调整。When it is detected that the target point corresponding to the electrode lead has shifted, the driving assembly is controlled to remove the electrode lead from the patient's skull, and the image acquisition device is used to obtain the first image of the patient again. The step of imaging data is to control the driving component to adjust the posture of the electrode lead.
在一些可选的实施例中,所述控制组件被配置成采用如下方式基于所述第一影像数据,控制所述驱动组件将所述电极导线植入所述患者的颅内:In some optional embodiments, the control component is configured to control the driving component to implant the electrode lead into the patient's skull based on the first image data in the following manner:
在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据;During the process of implanting the electrode lead using the driving assembly, the image acquisition device is used to obtain real-time image data of the patient;
基于所述患者的实时影像数据,检测所述电极导线是否偏离其所对应的参考路径;Based on the patient's real-time image data, detect whether the electrode lead deviates from its corresponding reference path;
当检测到所述电极导线未偏离其所对应的参考路径时,重新执行在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者 的实时影像数据的步骤;When it is detected that the electrode lead does not deviate from its corresponding reference path, re-execute the process of using the driving assembly to implant the electrode lead and using the image acquisition device to acquire the patient's image. The steps of real-time image data;
当检测到所述电极导线偏离其所对应的参考路径时,基于所述患者的当前影像数据,更新所述电极导线对应的参考路径,重新执行在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据的步骤。When it is detected that the electrode lead deviates from its corresponding reference path, the reference path corresponding to the electrode lead is updated based on the patient's current image data, and the process of implanting the electrode lead using the driving assembly is re-executed. During the process, the step of using the image acquisition device to obtain real-time image data of the patient.
在一些可选的实施例中,所述控制组件被配置成采用如下方式执行基于所述患者的实时影像数据,检测所述电极导线是否偏离其所对应的参考路径的步骤:In some optional embodiments, the control component is configured to perform the step of detecting whether the electrode lead deviates from its corresponding reference path based on the patient's real-time image data in the following manner:
基于预设时长内所述患者的实时影像数据,获取所述预设时长内所述电极导线对应的多个位置数据;Based on the real-time image data of the patient within the preset time period, obtain multiple position data corresponding to the electrode leads within the preset time period;
基于所述多个位置数据,获取所述电极导线对应的实际路径;Based on the plurality of position data, obtain the actual path corresponding to the electrode lead;
利用路径相似度模型对所述电极导线对应的实际路径和参考路径进行相似度计算,得到所述电极导线对应的路径相似度;Use a path similarity model to calculate the similarity between the actual path corresponding to the electrode wire and the reference path to obtain the path similarity corresponding to the electrode wire;
基于所述电极导线对应的路径相似度,检测所述电极导线是否偏离其所对应的参考路径。Based on the path similarity corresponding to the electrode wire, it is detected whether the electrode wire deviates from its corresponding reference path.
在一些可选的实施例中,所述电极导线对应的参考路径的获取过程包括:In some optional embodiments, the process of obtaining the reference path corresponding to the electrode wire includes:
基于所述第一影像数据,获取所述电极导线对应的目标靶点的位姿信息;Based on the first image data, obtain the pose information of the target target corresponding to the electrode lead;
基于所述电极导线对应的目标靶点的位姿信息,获取所述电极导线对应的参考路径。Based on the pose information of the target point corresponding to the electrode lead, the reference path corresponding to the electrode lead is obtained.
在一些可选的实施例中,所述控制组件被配置成采用如下方式获取所述电极导线对应的目标靶点的位姿信息:In some optional embodiments, the control component is configured to obtain the pose information of the target target corresponding to the electrode lead in the following manner:
基于所述第一影像数据,生成所述患者的颅脑模型;Generate a brain model of the patient based on the first imaging data;
基于所述患者的颅脑模型,获取每个电极导线对应的目标靶点的位姿信息。Based on the patient's brain model, the pose information of the target target corresponding to each electrode lead is obtained.
本申请还提供了一种手术机器人的控制系统,被配置成控制手术机器人将未植入的每个电极导线植入患者颅内;This application also provides a control system for a surgical robot configured to control the surgical robot to implant each unimplanted electrode lead into the patient's skull;
所述系统包括:The system includes:
第一影像数据获取装置,被配置成利用影像采集设备获取所述患者的第一影像数据;A first image data acquisition device configured to acquire first image data of the patient using an image acquisition device;
驱动组件控制装置,被配置成基于所述第一影像数据,控制所述手术机器人的驱动组件将所述电极导线植入所述患者的颅内;a driving component control device configured to control the driving component of the surgical robot to implant the electrode lead into the patient's skull based on the first image data;
第二影像数据获取装置,被配置成利用所述影像采集设备获取所述患者的 第二影像数据;The second image data acquisition device is configured to use the image acquisition device to acquire the patient's second image data;
目标靶点检测装置,被配置成基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移;A target target point detection device configured to detect whether the target target point corresponding to the electrode lead is offset based on the first image data and the second image data;
电极导线调整装置,被配置成当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与其所对应的目标靶点相匹配。The electrode lead adjustment device is configured to control the driving assembly to adjust the posture of the electrode lead when it detects that the target target point corresponding to the electrode lead is offset, so that the posture of the electrode lead is adjusted. Matches its corresponding target target.
附图说明Description of the drawings
图1是本申请实施例提供的一种手术机器人的控制方法的流程示意图;Figure 1 is a schematic flowchart of a control method for a surgical robot provided by an embodiment of the present application;
图2是本申请实施例提供的一种检测目标靶点是否发生偏移的流程示意图;Figure 2 is a schematic flowchart of detecting whether a target target point has shifted according to an embodiment of the present application;
图3是本申请实施例提供的一种调整电极导线的位姿的流程示意图;Figure 3 is a schematic flowchart of adjusting the position and posture of electrode leads provided by an embodiment of the present application;
图4是本申请实施例提供的一种植入电极导线的流程示意图;Figure 4 is a schematic flow chart of implanting electrode leads provided by an embodiment of the present application;
图5是本申请实施例提供的一种手术机器人的结构框图;Figure 5 is a structural block diagram of a surgical robot provided by an embodiment of the present application;
图6是本申请实施例提供的一种手术机器人的控制系统的结构框图。Figure 6 is a structural block diagram of a control system for a surgical robot provided by an embodiment of the present application.
具体实施方式Detailed ways
下面结合附图以及实施方式,对本申请做描述,在不相冲突的前提下,以下描述的多个实施例之间或多个技术特征之间可以任意组合形成新的实施例。The present application will be described below with reference to the accompanying drawings and embodiments. On the premise that there is no conflict, multiple embodiments or multiple technical features described below can be arbitrarily combined to form new embodiments.
对本申请的应用领域进行简单说明。Briefly describe the application fields of this application.
植入式医疗设备是一种植入式的可程控多程序医疗设备,可以是植入式神经电刺激装置、植入式心脏电刺激系统(又称心脏起搏器)、植入式药物输注装置(Implantable Drug Delivery System,IDDS)和导线转接装置中的任意一种。植入式神经电刺激装置例如是脑深部电刺激(Deep Brain Stimulation,DBS)系统,植入式脑皮层刺激(Cortical Nerve Stimulation,CNS)系统,植入式脊髓电刺激(Spinal Cord Stimulation,SCS)系统,植入式骶神经电刺激(Sacral Nerve Stimulation,SNS)系统,植入式迷走神经电刺激(Vagus Nerve Stimulation,VNS)系统等。所述植入式医疗设备例如是刺激器,刺激器包括植入式脉冲发生器(Implantable Pulse Generator,IPG)、延伸导线和电极导线,IPG设置于患者体内,依靠密封电池和电路提供可控制的电脉冲刺激,通过植入的延伸导线和电极导线,为生物体组织的特定区域提供一路或两路可控制的特定电脉冲刺激。延伸导线配合IPG使用,作为脉冲传递媒体,将IPG产生的刺激脉冲,传递给电极导线。电极导线将IPG产生的电刺激,通过多个电极触点,传递给生物体 组织的特定区域;所述植入式医疗设备具有单侧或双侧的一路或多路电极导线,所述电极导线上设置有多个电极触点,所述电极触点可以均匀排列或者非均匀排列在电极导线的周向上,例如所述电极触点以4行3列的阵列(共计12个电极触点)排列在电极导线的周向上。Implantable medical equipment is an implantable programmable multi-program medical equipment, which can be an implanted nerve electrical stimulation device, an implantable cardiac electrical stimulation system (also known as a pacemaker), or an implantable drug infusion Any one of the Implantable Drug Delivery System (IDDS) and the lead adapter device. Implantable neuroelectric stimulation devices include, for example, Deep Brain Stimulation (DBS) system, Implantable Cortical Nerve Stimulation (CNS) system, and Implantable Spinal Cord Stimulation (SCS) system. system, implantable sacral nerve stimulation (Sacral Nerve Stimulation, SNS) system, implantable vagus nerve stimulation (Vagus Nerve Stimulation, VNS) system, etc. The implantable medical device is, for example, a stimulator. The stimulator includes an Implantable Pulse Generator (IPG), extension wires, and electrode wires. The IPG is placed in the patient's body and relies on a sealed battery and circuit to provide controllable Electrical pulse stimulation provides one or two controllable specific electrical pulse stimulations to specific areas of biological tissue through implanted extension wires and electrode wires. The extension lead is used in conjunction with the IPG as a pulse transmission medium to deliver the stimulation pulse generated by the IPG to the electrode lead. The electrode lead transmits the electrical stimulation generated by the IPG to the living body through multiple electrode contacts. A specific area of the tissue; the implantable medical device has one or more electrode leads on one or both sides. Multiple electrode contacts are provided on the electrode leads. The electrode contacts can be arranged evenly or non-uniformly. Arranged in the circumferential direction of the electrode lead, for example, the electrode contacts are arranged in an array of 4 rows and 3 columns (a total of 12 electrode contacts) in the circumferential direction of the electrode lead.
在本申请的一个实施方式中,受刺激的生物体组织可以是患者的脑组织,受刺激的部位可以是脑组织的特定部位,当患者的疾病类型不同时,受刺激的部位一般来说是不同的,所使用的刺激触点(单源或多源)的数量、一路或多路(单通道或多通道)特定电脉冲刺激的运用以及刺激参数数据也是不同的。本申请对适用的疾病类型不做限定,疾病类型可以是脑深部刺激(DBS)、脊髓刺激(SCS)、骨盆刺激、胃刺激、外周神经刺激、功能性电刺激所适用的疾病类型。其中,DBS可以用于治疗或管理的疾病类型包括:痉挛疾病(例如,癫痫)、疼痛、偏头痛、精神疾病(例如,重度抑郁症(Major Depressive Disorder,MDD))、躁郁症、焦虑症、创伤后压力心理障碍症、轻郁症、强迫症(Obsessive-Compulsive Disorder,OCD)、行为障碍、情绪障碍、记忆障碍、心理状态障碍、移动障碍(例如,特发性震颤或帕金森氏病)、亨廷顿病、阿尔茨海默症、药物成瘾症、自闭症或其他神经学或精神科疾病和损害。当DBS用于治疗药物成瘾症患者时,可以帮助吸毒人员戒毒,提升他们的幸福感和生命质量。In one embodiment of the present application, the stimulated biological tissue can be the patient's brain tissue, and the stimulated site can be a specific part of the brain tissue. When the patient's disease type is different, the stimulated site is generally Different, the number of stimulation contacts used (single source or multiple sources), the use of one or more channels (single channel or multiple channels) of specific electrical pulse stimulation, and stimulation parameter data are also different. This application does not limit the applicable disease types. The disease types can be those applicable to deep brain stimulation (DBS), spinal cord stimulation (SCS), pelvic stimulation, gastric stimulation, peripheral nerve stimulation, and functional electrical stimulation. Among them, the types of diseases that DBS can be used to treat or manage include: spastic diseases (such as epilepsy), pain, migraine, mental illness (such as major depressive disorder (Major Depressive Disorder, MDD)), bipolar disorder, anxiety disorder , post-traumatic stress disorder, mild depression, obsessive-compulsive disorder (OCD), behavioral disorders, mood disorders, memory disorders, mental status disorders, movement disorders (such as essential tremor or Parkinson's disease ), Huntington's disease, Alzheimer's disease, substance addiction disorders, autism, or other neurological or psychiatric diseases and impairments. When DBS is used to treat patients with drug addiction, it can help drug addicts detoxify and improve their happiness and quality of life.
参见图1,本申请实施例提供了一种手术机器人的控制方法,所述手术机器人被配置成将至少两个电极导线植入患者颅内,所述手术机器人包括驱动组件以及控制组件。Referring to Figure 1, an embodiment of the present application provides a method for controlling a surgical robot. The surgical robot is configured to implant at least two electrode leads into a patient's skull. The surgical robot includes a driving component and a control component.
针对未植入的每个电极导线,所述方法包括步骤S1~步骤S5。For each electrode lead that is not implanted, the method includes steps S1 to S5.
S1:利用影像采集设备获取所述患者的第一影像数据。S1: Use image acquisition equipment to obtain the first image data of the patient.
S2:基于所述第一影像数据,控制所述驱动组件将所述电极导线植入所述患者的颅内。S2: Based on the first image data, control the driving component to implant the electrode lead into the patient's skull.
S3:利用所述影像采集设备获取所述患者的第二影像数据。S3: Use the image acquisition device to obtain the second image data of the patient.
S4:基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移。S4: Based on the first image data and the second image data, detect whether the target target corresponding to the electrode lead is offset.
S5:当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配。S5: When it is detected that the target point corresponding to the electrode lead is offset, control the driving component to adjust the posture of the electrode lead so that the posture of the electrode lead is consistent with the position of the electrode lead. The corresponding target targets match.
由此,在植入每个电极导线之前,获取第一影像数据,以第一影像数据作为参考,将电极导线植入患者颅内,植入完成后,获取第二影像数据,比较第 一影像数据和第二影像数据,根据比对结果检测电极导线对应的目标靶点是否发生偏移,对目标靶点发生偏移的电极导线进行位姿的调整,确保电极导线的位置与电极导线对应的目标靶点匹配。Therefore, before implanting each electrode lead, the first image data is acquired, and the electrode lead is implanted into the patient's skull using the first image data as a reference. After the implantation is completed, the second image data is acquired, and the second image data is compared with the first image data. Based on the comparison results of the first image data and the second image data, it is detected whether the target point corresponding to the electrode lead has shifted, and the posture of the electrode lead with the offset target point is adjusted to ensure that the position of the electrode lead is consistent with the electrode lead. Corresponding target target matches.
相关技术只在植入电极导线前获取一次影像数据,在电极导线植入后不考虑目标靶点发生偏移的情况,而本申请在植入电极导线前后均需要获取影像数据,植入电极导线前获取第一影像数据,植入电极导线后获取第二影像数据,第一影像数据的作用是作为电极导线植入时的参考依据,第二影像数据的作用是结合第一影像数据,作为目标靶点是否发生偏移的判断依据,在检测到目标靶点发生偏移时,对目标靶点发生偏移的电极导线进行位姿的调整,使得电极导线的刺激部位不会偏离电极导线对应的靶点的位置,保障电极导线的植入效果。The related technology only acquires image data once before implanting the electrode lead, and does not consider the deviation of the target point after the electrode lead is implanted. However, this application needs to acquire image data before and after implanting the electrode lead, and the electrode lead is implanted. The first image data is obtained before the electrode lead is implanted, and the second image data is obtained after the electrode lead is implanted. The first image data is used as a reference when the electrode lead is implanted, and the second image data is combined with the first image data as a target. The basis for judging whether the target point has shifted is that when it is detected that the target point has shifted, the posture of the electrode lead that has shifted the target point is adjusted so that the stimulation site of the electrode lead does not deviate from the corresponding position of the electrode lead. The position of the target ensures the implantation effect of the electrode lead.
本申请对“至少两个电极导线”中的至少两个不作限定,其可以是预先设定的值,例如2个、6个、8个或者11个。This application does not limit at least two of the "at least two electrode wires", which may be a preset value, such as 2, 6, 8 or 11.
在一些实施方式中,手术机器人需要将8个电极导线植入患者颅内,在对其中的1个完成植入后,针对还未植入的7个电极导线,采用上述控制方法将这7个电极导线挨个地依次植入患者颅内。In some embodiments, the surgical robot needs to implant 8 electrode leads into the patient's skull. After completing the implantation of 1 of them, the 7 electrode leads that have not yet been implanted are used to control the 7 electrode leads as described above. The electrode leads are implanted into the patient's skull one by one.
本申请实施例对手术机器人的结构不作限定,其可以采用CN111631815A、CN111419400A、CN108066011A或CN114098971A公开的任意一种手术机器人。The embodiment of the present application does not limit the structure of the surgical robot, and any surgical robot disclosed in CN111631815A, CN111419400A, CN108066011A or CN114098971A can be used.
驱动组件可以包括提供动力的动力机构、执行穿刺操作的穿刺执行机构和带动电极导线完成植入操作的传送机构。动力机构可以包括电机以及气缸等,穿刺机构可以包括穿刺针和套筒。The driving assembly may include a power mechanism that provides power, a puncture actuator that performs the puncture operation, and a transmission mechanism that drives the electrode lead to complete the implantation operation. The power mechanism may include a motor, a cylinder, etc., and the puncture mechanism may include a puncture needle and a sleeve.
控制组件的控制功能可以由微处理器(Microprocessor Unit,MPU)、微控制单元(Microcontroller Unit,MCU)、(Digital Signal Processor,DSP)、现场可编程门阵列(Field Programmable Gate Array,FPGA)或其任意组合来实现。The control function of the control component can be controlled by a microprocessor (Microprocessor Unit, MPU), a microcontroller unit (MCU), a Digital Signal Processor (DSP), a field programmable gate array (Field Programmable Gate Array, FPGA) or other Any combination can be achieved.
本申请实施例对影像采集设备不作限定,影像采集设备可以采用电子计算机断层扫描(Computed Tomography,CT)扫描设备、核磁共振扫描仪、超声波扫描仪中的任意一种。当影像采集设备为核磁共振扫描仪时,手术机器人的材质采用磁共振(Magnetic Resonance,MR)兼容的材料。The embodiments of the present application do not limit the image acquisition equipment. The image acquisition equipment may be any one of computerized tomography (CT) scanning equipment, magnetic resonance scanner, and ultrasonic scanner. When the image acquisition device is an MRI scanner, the surgical robot is made of magnetic resonance (Magnetic Resonance, MR) compatible materials.
利用影像采集设备获取的影像数据可以包括CT扫描影像、核磁共振影像(Magnetic Resonance Imaging,MRI)、放射影像和超声波影像中的一种或多种。The image data acquired by the image acquisition equipment may include one or more of CT scan images, Magnetic Resonance Imaging (MRI), radiological images, and ultrasound images.
DBS的基本思路是使用电极对脑内的特定位置进行刺激,这些位置称为靶点。靶点的选择对治疗效果起到重要作用。The basic idea of DBS is to use electrodes to stimulate specific locations in the brain, called targets. The selection of target plays an important role in the effectiveness of treatment.
对于不同的疾病或者症状,需要选择特定的靶点。例如帕金森患者的常用 治疗靶点是丘脑底核和苍白球内侧部,而震颤患者的常用靶点为丘脑腹中央核。For different diseases or symptoms, specific targets need to be selected. For example, commonly used by Parkinson’s patients Treatment targets are the subthalamic nucleus and the medial part of the globus pallidus, while a common target in patients with tremor is the ventromedial nucleus of the thalamus.
本申请的目标靶点为所述患者进行植入手术所对应的靶点。The target target of this application is the target corresponding to the patient's implantation surgery.
参见图2,在一些可选的实施例中,所述步骤S4可以包括步骤S41~S43。Referring to Figure 2, in some optional embodiments, step S4 may include steps S41 to S43.
步骤S41:获取每个目标靶点在所述第一影像数据中的第一边界框位置信息。Step S41: Obtain the first bounding box position information of each target point in the first image data.
步骤S42:获取每个目标靶点在所述第二影像数据中的第二边界框位置信息。Step S42: Obtain the second bounding box position information of each target point in the second image data.
步骤S43:基于每个目标靶点对应的第一边界框位置信息和第二边界框位置信息,检测所述电极导线对应的目标靶点是否发生偏移。Step S43: Based on the first bounding box position information and the second bounding box position information corresponding to each target target point, detect whether the target target point corresponding to the electrode lead is offset.
由此,通过分别获取每个目标靶点对应的第一边界框位置信息和第二边界框位置信息,可以比较每个目标靶点在第一影像数据中的边界框位置和第二影像数据中的边界框位置,根据边界框位置的比较结果,检测目标靶点是否发生偏移。Therefore, by respectively obtaining the first bounding box position information and the second bounding box position information corresponding to each target target point, the bounding box position of each target target point in the first image data and the second image data can be compared. The position of the bounding box, and based on the comparison result of the position of the bounding box, detect whether the target target has shifted.
相比于人工检测目标靶点是否发生偏移的方式,这种利用边界框位置信息自动检测目标靶点是否发生偏移方式的效率较高、误差较小。Compared with the method of manually detecting whether the target point has shifted, this method of automatically detecting whether the target point has shifted using the bounding box position information is more efficient and has smaller errors.
在目标检测中,通常使用边界框(bounding box)来描述目标对象的空间位置。当边界框是矩形时,边界框的位置可以由矩形左上角的横坐标和纵坐标以及矩形右下角的横坐标和纵坐标来确定。或者,边界框的位置还可以使用边界框中心的横坐标和纵坐标以及边界框的宽度和高度来确定。In target detection, bounding boxes are usually used to describe the spatial location of target objects. When the bounding box is a rectangle, the position of the bounding box can be determined by the abscissa and ordinate of the upper left corner of the rectangle and the abscissa and ordinate of the lower right corner of the rectangle. Alternatively, the position of the bounding box can also be determined using the abscissa and ordinate of the center of the bounding box and the width and height of the bounding box.
在一些可选的实施例中,所述步骤S43可以包括:In some optional embodiments, step S43 may include:
利用文本相似度模型对每个目标靶点对应的第一边界框位置信息和第二边界框位置信息进行相似度计算,得到每个目标靶点对应的位置相似度;Use the text similarity model to calculate the similarity of the first bounding box position information and the second bounding box position information corresponding to each target target, and obtain the position similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的位置相似度小于第一相似度阈值时,确定所述电极导线对应的目标靶点发生偏移。When the position similarity corresponding to the target point corresponding to the electrode lead is less than the first similarity threshold, it is determined that the target target point corresponding to the electrode lead has shifted.
由此,可以利用文本相似度模型直接对第一边界框位置信息和第二边界框位置信息进行相似度计算,得到每个目标靶点对应的位置相似度,这种计算方式计算的是文本之间的相似度,计算量较小,检测效率较高。Therefore, the text similarity model can be used to directly calculate the similarity between the first bounding box position information and the second bounding box position information to obtain the position similarity corresponding to each target target. This calculation method calculates the similarity between the text. The similarity between them is small, and the detection efficiency is high.
本申请对文本相似度模型不作限定,其可以采用CN113723070A、CN111353033A、CN111626039A公开的任意一种文本相似度模型。This application does not limit the text similarity model, which can adopt any text similarity model disclosed in CN113723070A, CN111353033A, and CN111626039A.
本申请对第一相似度阈值的大小不作限定,第一相似度阈值例如可以是70%、85%或者90%。 This application does not limit the size of the first similarity threshold. The first similarity threshold may be, for example, 70%, 85% or 90%.
在一些可选的实施例中,所述步骤S43可以包括:In some optional embodiments, step S43 may include:
基于每个目标靶点对应的第一边界框位置信息,从所述第一影像数据中截取得到每个目标靶点对应的预设区域的第一子图像;Based on the first bounding box position information corresponding to each target target point, intercept the first sub-image of the preset area corresponding to each target target point from the first image data;
基于每个目标靶点对应的第二边界框位置信息,从所述第二影像数据中截取得到每个目标靶点对应的预设区域的第二子图像;Based on the second bounding box position information corresponding to each target target point, intercept the second sub-image of the preset area corresponding to each target target point from the second image data;
利用图像相似度模型对每个目标靶点对应的第一子图像和第二子图像进行相似度计算,得到每个目标靶点对应的图像相似度;Use the image similarity model to calculate the similarity of the first sub-image and the second sub-image corresponding to each target target, and obtain the image similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的图像相似度小于第二相似度阈值时,确定所述电极导线对应的目标靶点发生偏移。When the image similarity corresponding to the target point corresponding to the electrode lead is less than the second similarity threshold, it is determined that the target target point corresponding to the electrode lead is shifted.
由此,在得到第一边界框位置信息后,从第一影像数据中截取得到每个目标靶点对应的预设区域的第一子图像,在得到第二边界框位置信息后,从第二影像数据中截取得到每个目标靶点对应的预设区域的第二子图像,预设区域的大小可以与边界框的大小相对应,得到第一子图像和第二子图像后,可以利用图像相似度模型计算得到每个目标靶点对应的图像相似度,这种计算方式计算的是图像之间的相似度,检测精度较高。Thus, after obtaining the first bounding box position information, the first sub-image of the preset area corresponding to each target target point is intercepted from the first image data, and after obtaining the second bounding box position information, the first sub-image of the preset area corresponding to each target target is obtained from the second image data. The second sub-image of the preset area corresponding to each target target is intercepted from the image data. The size of the preset area can correspond to the size of the bounding box. After obtaining the first sub-image and the second sub-image, the image can be used The similarity model calculates the image similarity corresponding to each target target. This calculation method calculates the similarity between images and has higher detection accuracy.
本申请对图像相似度模型不作限定,其可以采用CN114140664A、CN112052868A、CN1926575A、CN112633420A公开的任意一种图像相似度模型。This application does not limit the image similarity model, which can adopt any image similarity model disclosed in CN114140664A, CN112052868A, CN1926575A, and CN112633420A.
预设区域可以是预先设定的区域,本申请对预设区域的大小不作限定,其大小可以是4×4mm、4×5mm或者6×8mm。The preset area may be a preset area. This application does not limit the size of the preset area. The size may be 4×4 mm, 4×5 mm or 6×8 mm.
本申请对第二相似度阈值的大小不作限定,第二相似度阈值例如可以是70%、85%或者90%。This application does not limit the size of the second similarity threshold. The second similarity threshold may be, for example, 70%, 85% or 90%.
在一些可选的实施例中,所述步骤S5可以包括:In some optional embodiments, step S5 may include:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件将所述电极导线向下深入或者向上提取,以使所述电极导线的位姿与其所对应的目标靶点相匹配。When it is detected that the target point corresponding to the electrode lead is offset, the driving assembly is controlled to deepen the electrode lead downward or extract it upward, so that the posture of the electrode lead is consistent with the corresponding target point. match.
由此,一般而言,受限于手术机器人的驱动组件的自身的精度,电极导线实际的植入部位可能与预期的植入部位有些微的偏差,例如驱动组件可以包括气缸、穿刺针和套管等,而气缸的精度可能只有1mm,这就导致电极导线实际的植入部位与预期的植入部位有一定的偏差,此时无需进行大幅度的调整,只需将电极导线沿其预先设定的参考路径稍稍向下深入或者向上提取,就可以使电极导线的位姿与其所对应的目标靶点相匹配,这种方式无需重新规划路径并 重新进行穿刺打孔,对患者的伤害较小,较为安全,且手术时间短,提升医生的治疗效率,使医生能够服务更多患者。Therefore, generally speaking, the actual implantation site of the electrode lead may deviate slightly from the expected implantation site due to the accuracy of the driving assembly of the surgical robot. For example, the driving assembly may include a cylinder, a puncture needle, and a sheath. tubes, etc., and the accuracy of the cylinder may be only 1mm, which results in a certain deviation between the actual implantation site of the electrode lead and the expected implantation site. At this time, there is no need to make major adjustments, and you only need to move the electrode lead along its preset By slightly deepening or extracting the predetermined reference path upward, the posture of the electrode lead can be matched with its corresponding target point. This method does not require re-planning of the path and Re-performing the puncture will cause less harm to the patient, is safer, and the operation time is short, which improves the doctor's treatment efficiency and enables the doctor to serve more patients.
参见图3,在一些可选的实施例中,所述步骤S5可以包括:Referring to Figure 3, in some optional embodiments, step S5 may include:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件将所述电极导线从所述患者的颅内移除,重新执行步骤S1,以控制所述驱动组件对所述电极导线进行位姿的调整。When it is detected that the target point corresponding to the electrode lead has shifted, the driving component is controlled to remove the electrode lead from the patient's skull, and step S1 is re-executed to control the driving component to move the target point corresponding to the electrode lead. Adjust the posture of the electrode lead.
由此,当电极导线对应的目标靶点偏移的幅度较大,通过向下深入或者向上提取的方式已经无法实现靶点的匹配时,可以先将电极导线移除,重新执行步骤S1,从而完成步骤S1~步骤S5的循环操作,直到所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配,才结束循环,通过重新设定电极导线对应的路径,通过重新植入的方式使得电极导线的位置与电极导线对应的靶点匹配,保障电极导线的植入效果。Therefore, when the target point corresponding to the electrode lead has a large deviation and the target point cannot be matched by deepening downward or extracting upward, the electrode lead can be removed first and step S1 can be performed again, so that Complete the loop operation of steps S1 to S5 until the posture of the electrode lead matches the target point corresponding to the electrode lead, then the cycle ends. By resetting the path corresponding to the electrode lead, and by re-implantation This method makes the position of the electrode lead match the target point corresponding to the electrode lead, ensuring the implantation effect of the electrode lead.
在一些可选的实施例中,所述方法还可以包括:In some optional embodiments, the method may further include:
当所有所述电极导线均植入所述患者的颅内后,利用所述影像采集设备获取所述患者的第三影像数据;After all the electrode leads are implanted into the patient's skull, use the image acquisition device to obtain the third image data of the patient;
基于所述第一影像数据和所述第三影像数据,检测所有所述电极导线对应的目标靶点是否发生偏移;Based on the first image data and the third image data, detect whether the target target points corresponding to all the electrode leads are offset;
当至少一个电极导线对应的目标靶点发生偏移时,将目标靶点发生偏移的电极导线记为待调电极导线,控制所述驱动组件将所述待调电极导线向下深入或者向上提取;When the target point corresponding to at least one electrode lead is offset, the electrode lead with the offset target point is recorded as the electrode lead to be adjusted, and the driving assembly is controlled to deepen the electrode lead to be adjusted downward or extract it upward. ;
当待调电极导线对应的目标靶点偏移的幅度较大,通过向下深入或者向上提取的方式已经无法实现靶点的匹配时,可以先将待调电极导线移除,再执行S1,重新规划路径并进行穿刺打孔等操作。When the target point corresponding to the electrode lead to be adjusted has a large deviation, and the target point cannot be matched by deepening downward or extracting upward, you can first remove the electrode lead to be adjusted, then execute S1, and restart Plan the path and perform operations such as puncture and drilling.
参见图4,在一些可选的实施例中,所述步骤S2可以包括步骤S21~步骤S24。Referring to Figure 4, in some optional embodiments, step S2 may include steps S21 to S24.
S21:在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据。S21: During the process of implanting the electrode lead using the driving assembly, use the image acquisition device to obtain real-time image data of the patient.
S22:基于所述患者的实时影像数据,检测所述电极导线是否偏离其所对应的参考路径。S22: Based on the patient's real-time image data, detect whether the electrode lead deviates from its corresponding reference path.
S23:当检测到所述电极导线未偏离其所对应的参考路径时,重新执行S21。S23: When it is detected that the electrode wire does not deviate from its corresponding reference path, perform S21 again.
S24:当检测到所述电极导线偏离其所对应的参考路径时,基于所述患者的当前影像数据,更新所述电极导线对应的参考路径,重新执行S21。 S24: When it is detected that the electrode lead deviates from its corresponding reference path, update the reference path corresponding to the electrode lead based on the current image data of the patient, and re-execute S21.
由此,考虑到电极导线在植入的过程中可能存在偏离预先设定的参考路径的情况,在植入每一个电极导线的过程中,获取患者的实时影像数据,以实时影像数据为准,检测电极导线是否偏离其所对应的参考路径,当电极导线未偏离其所对应的参考路径时,继续执行S21,当电极导线偏离其所对应的参考路径时,根据患者的当前影像数据,更新参考路径,执行S21,这种方式以实时影像数据为依据,实现电极导线的路径的自适应更新,在植入过程之中就可以调整电极导线的位姿,保障电极导线的植入效果。Therefore, considering that the electrode leads may deviate from the preset reference path during the implantation process, the patient's real-time image data is obtained during the implantation of each electrode lead, and the real-time image data shall prevail. Detect whether the electrode lead deviates from its corresponding reference path. When the electrode lead does not deviate from its corresponding reference path, continue to execute S21. When the electrode lead deviates from its corresponding reference path, update the reference according to the patient's current image data. Path, execute S21. This method is based on real-time image data to realize adaptive updating of the path of the electrode lead. During the implantation process, the posture of the electrode lead can be adjusted to ensure the implantation effect of the electrode lead.
在一些可选的实施例中,所述步骤S22可以包括:In some optional embodiments, step S22 may include:
基于预设时长内所述患者的实时影像数据,获取所述预设时长内所述电极导线对应的多个位置数据;Based on the real-time image data of the patient within the preset time period, obtain multiple position data corresponding to the electrode leads within the preset time period;
基于所述多个位置数据,获取所述电极导线对应的实际路径;Based on the plurality of position data, obtain the actual path corresponding to the electrode lead;
利用路径相似度模型对所述电极导线对应的实际路径和参考路径进行相似度计算,得到所述电极导线对应的路径相似度;Use a path similarity model to calculate the similarity between the actual path corresponding to the electrode wire and the reference path to obtain the path similarity corresponding to the electrode wire;
基于所述电极导线对应的路径相似度,检测所述电极导线是否偏离其所对应的参考路径。Based on the path similarity corresponding to the electrode wire, it is detected whether the electrode wire deviates from its corresponding reference path.
由此,可以根据预设时长内的多个实时影像数据,得到电极导线对应的多个位置数据,根据这多个位置数据,获取电极导线对应的实际路径,利用路径相似度模型对实际路径和参考路径进行相似度计算,得到电极导线对应的路径相似度,这种方式的检测精度较高。并且,当预设时长内的实时影像数据足够多,例如有一百个时,得到的实际路径较为贴合电极导线实际植入过程中的路径。Thus, multiple position data corresponding to the electrode lead can be obtained based on multiple real-time image data within a preset time period. Based on these multiple position data, the actual path corresponding to the electrode lead can be obtained, and the path similarity model can be used to compare the actual path and Calculate the similarity using the reference path to obtain the path similarity corresponding to the electrode wires. This method has higher detection accuracy. Moreover, when there are enough real-time image data within the preset time period, for example, one hundred, the actual path obtained is more consistent with the path of the actual electrode lead implantation process.
预设时长可以是预先设定的时长,本申请对预设时长不作限定,预设时长可以是1分钟、3分钟或者5分钟。The preset duration may be a preset duration. This application does not limit the preset duration. The preset duration may be 1 minute, 3 minutes or 5 minutes.
本申请对路径相似度模型的形式不作限定,其可以采用机器学习模型、深度学习模型以及强化学习模型等训练而成。This application does not limit the form of the path similarity model, which can be trained using a machine learning model, a deep learning model, a reinforcement learning model, etc.
在一些实施方式中,路径相似度模型的训练过程可以包括:In some implementations, the training process of the path similarity model may include:
获取多个相似度训练数据,每个所述相似度训练数据包括用于训练的样本参考路径、样本实际路径以及二者的标注相似度;Acquire multiple similarity training data, each of which includes a sample reference path used for training, a sample actual path, and the annotated similarity between the two;
利用多个所述相似度训练数据训练预设的深度学习模型,得到路径相似度模型。A plurality of the similarity training data are used to train a preset deep learning model to obtain a path similarity model.
在一些实施方式中,当所述电极导线对应的路径相似度小于第三相似度阈值时,确定所述电极导线偏离其所对应的参考路径; In some embodiments, when the path similarity corresponding to the electrode lead is less than a third similarity threshold, it is determined that the electrode lead deviates from its corresponding reference path;
当所述电极导线对应的路径相似度不小于第三相似度阈值时,确定所述电极导线未偏离其所对应的参考路径。When the path similarity corresponding to the electrode lead is not less than the third similarity threshold, it is determined that the electrode lead has not deviated from its corresponding reference path.
本申请对第三相似度阈值的大小不作限定,第三相似度阈值例如可以是70%、85%或者90%。This application does not limit the size of the third similarity threshold. The third similarity threshold may be, for example, 70%, 85% or 90%.
在一些可选的实施例中,所述电极导线对应的参考路径的获取过程包括:In some optional embodiments, the process of obtaining the reference path corresponding to the electrode wire includes:
基于所述第一影像数据,获取所述电极导线对应的目标靶点的位姿信息;Based on the first image data, obtain the pose information of the target target corresponding to the electrode lead;
基于所述电极导线对应的目标靶点的位姿信息,获取所述电极导线对应的参考路径。Based on the pose information of the target point corresponding to the electrode lead, the reference path corresponding to the electrode lead is obtained.
由此,可以根据第一影像数据,获取电极导线对应的目标靶点的位姿信息,根据电极导线对应的目标靶点的位姿信息,自动规划电极导线对应的参考路径,无需人工规划路径,且目标靶点的位姿信息可用于可视化显示。Thus, the pose information of the target point corresponding to the electrode lead can be obtained based on the first image data, and the reference path corresponding to the electrode lead can be automatically planned based on the pose information of the target point corresponding to the electrode lead, without the need for manual path planning. And the pose information of the target target can be used for visual display.
在一些可选的实施例中,所述获取所述电极导线对应的目标靶点的位姿信息可以包括:In some optional embodiments, obtaining the pose information of the target target corresponding to the electrode lead may include:
基于所述第一影像数据,生成所述患者的颅脑模型;Generate a brain model of the patient based on the first imaging data;
基于所述患者的颅脑模型,获取每个电极导线对应的目标靶点的位姿信息。Based on the patient's brain model, the pose information of the target target corresponding to each electrode lead is obtained.
由此,根据第一影像数据,自动生成患者的颅脑模型,通过患者的颅脑模型,得到每个电极导线对应的目标靶点的位姿信息,可以在该颅脑模型上直观地显示每个电极导线对应的目标靶点的位置和姿态。As a result, the patient's brain model is automatically generated based on the first image data. Through the patient's brain model, the pose information of the target point corresponding to each electrode lead is obtained, and each electrode can be intuitively displayed on the brain model. The position and attitude of the target target corresponding to each electrode lead.
在一些实施方式中,颅脑模型可以是脑部三维模型。生成颅脑模型的方式可以采用CN112669938A所公开的方式。In some embodiments, the cranial model may be a three-dimensional model of the brain. The method of generating the brain model can adopt the method disclosed in CN112669938A.
位姿信息可以用于指示位置和姿态。在生成颅脑模型后,可以借助于人工智能和机器学习技术自动确定目标靶点的位置和姿态。Pose information can be used to indicate position and attitude. After the brain model is generated, the position and posture of the target target can be automatically determined with the help of artificial intelligence and machine learning technology.
以丘脑底核作为目标靶点进行举例,将颅脑模型进行人工智能(Artificial Intelligence,AI)处理,自动识别红核最大截面所在的层面,将在红核前缘水平切面的丘脑底核中点作为目标靶点,根据丘脑底核重心进行微调,即可确认目标靶点的位置。Taking the subthalamic nucleus as the target as an example, the brain model is processed by artificial intelligence (AI) to automatically identify the level where the largest cross-section of the red nucleus is located, and the midpoint of the subthalamic nucleus in the horizontal section at the front edge of the red nucleus is As the target target, the position of the target can be confirmed by fine-tuning based on the center of gravity of the subthalamic nucleus.
参见图5,本申请实施例还提供了一种手术机器人100,其实现方式与上述控制方法的实施例中记载的实施方式、所达到的技术效果一致,部分内容不再赘述。Referring to FIG. 5 , an embodiment of the present application also provides a surgical robot 100 , the implementation of which is consistent with the implementation and technical effects achieved described in the embodiment of the above control method, and part of the content will not be described again.
所述手术机器人100被配置成将至少两个电极导线植入患者颅内,所述手术机器人100包括驱动组件120以及控制组件110; The surgical robot 100 is configured to implant at least two electrode leads into the patient's skull, and the surgical robot 100 includes a driving component 120 and a control component 110;
针对未植入的每个电极导线,所述控制组件110被配置成执行如下步骤:For each electrode lead that is not implanted, the control component 110 is configured to perform the following steps:
S1:利用影像采集设备获取所述患者的第一影像数据。S1: Use image acquisition equipment to obtain the first image data of the patient.
S2:基于所述第一影像数据,控制所述驱动组件120将所述电极导线植入所述患者的颅内。S2: Based on the first image data, control the driving component 120 to implant the electrode lead into the patient's skull.
S3:利用所述影像采集设备获取所述患者的第二影像数据。S3: Use the image acquisition device to obtain the second image data of the patient.
S4:基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移。S4: Based on the first image data and the second image data, detect whether the target target corresponding to the electrode lead is offset.
S5:当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件120对所述电极导线进行位姿的调整,以使所述电极导线的位姿与其所对应的目标靶点相匹配。S5: When it is detected that the target point corresponding to the electrode lead deviates, control the driving component 120 to adjust the posture of the electrode lead so that the posture of the electrode lead is consistent with the corresponding target. target matches.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式执行步骤S4:In some optional embodiments, the control component 110 is configured to perform step S4 in the following manner:
获取每个目标靶点在所述第一影像数据中的第一边界框位置信息;Obtain the first bounding box position information of each target target in the first image data;
获取每个目标靶点在所述第二影像数据中的第二边界框位置信息;Obtain the second bounding box position information of each target target in the second image data;
基于每个目标靶点对应的第一边界框位置信息和第二边界框位置信息,检测所述电极导线对应的目标靶点是否发生偏移。Based on the first bounding box position information and the second bounding box position information corresponding to each target target point, it is detected whether the target target point corresponding to the electrode lead is offset.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式检测所述电极导线对应的目标靶点是否发生偏移:In some optional embodiments, the control component 110 is configured to detect whether the target target corresponding to the electrode lead has shifted in the following manner:
利用文本相似度模型对每个目标靶点对应的第一边界框位置信息和第二边界框位置信息进行相似度计算,得到每个目标靶点对应的位置相似度;Use the text similarity model to calculate the similarity of the first bounding box position information and the second bounding box position information corresponding to each target target, and obtain the position similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的位置相似度小于第一相似度阈值时,确定所述电极导线对应的目标靶点发生偏移。When the position similarity corresponding to the target point corresponding to the electrode lead is less than the first similarity threshold, it is determined that the target target point corresponding to the electrode lead has shifted.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式检测所述电极导线对应的目标靶点是否发生偏移:In some optional embodiments, the control component 110 is configured to detect whether the target target corresponding to the electrode lead has shifted in the following manner:
基于每个目标靶点对应的第一边界框位置信息,从所述第一影像数据中截取得到每个目标靶点对应的预设区域的第一子图像;Based on the first bounding box position information corresponding to each target target point, intercept the first sub-image of the preset area corresponding to each target target point from the first image data;
基于每个目标靶点对应的第二边界框位置信息,从所述第二影像数据中截取得到每个目标靶点对应的预设区域的第二子图像;Based on the second bounding box position information corresponding to each target target point, intercept the second sub-image of the preset area corresponding to each target target point from the second image data;
利用图像相似度模型对每个目标靶点对应的第一子图像和第二子图像进行相似度计算,得到每个目标靶点对应的图像相似度;Use the image similarity model to calculate the similarity of the first sub-image and the second sub-image corresponding to each target target, and obtain the image similarity corresponding to each target target;
当所述电极导线对应的目标靶点对应的图像相似度小于第二相似度阈值 时,确定所述电极导线对应的目标靶点发生偏移。When the image similarity corresponding to the target point corresponding to the electrode lead is less than the second similarity threshold When, it is determined that the target target corresponding to the electrode lead is shifted.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式执行步骤S5:In some optional embodiments, the control component 110 is configured to perform step S5 in the following manner:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件120将所述电极导线向下深入或者向上提取,以使所述电极导线的位姿与其所对应的目标靶点相匹配。When it is detected that the target point corresponding to the electrode lead is offset, the driving assembly 120 is controlled to deepen the electrode lead downward or extract it upward, so that the posture of the electrode lead is consistent with the corresponding target point. points match.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式执行步骤S5:In some optional embodiments, the control component 110 is configured to perform step S5 in the following manner:
当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件120将所述电极导线从所述患者的颅内移除,重新执行步骤S1,以控制所述驱动组件120对所述电极导线进行位姿的调整。When it is detected that the target point corresponding to the electrode lead has shifted, the driving component 120 is controlled to remove the electrode lead from the patient's skull, and step S1 is re-executed to control the driving component 120 Adjust the posture of the electrode lead.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式执行步骤S2:In some optional embodiments, the control component 110 is configured to perform step S2 in the following manner:
S21:在利用所述驱动组件120植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据。S21: During the process of implanting the electrode lead using the driving assembly 120, use the image acquisition device to acquire real-time image data of the patient.
S22:基于所述患者的实时影像数据,检测所述电极导线是否偏离其所对应的参考路径。S22: Based on the patient's real-time image data, detect whether the electrode lead deviates from its corresponding reference path.
S23:当检测到所述电极导线未偏离其所对应的参考路径时,重新执行S21。S23: When it is detected that the electrode wire does not deviate from its corresponding reference path, perform S21 again.
S24:当检测到所述电极导线偏离其所对应的参考路径时,基于所述患者的当前影像数据,更新所述电极导线对应的参考路径,重新执行S21。S24: When it is detected that the electrode lead deviates from its corresponding reference path, update the reference path corresponding to the electrode lead based on the current image data of the patient, and re-execute S21.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式执行步骤S22:In some optional embodiments, the control component 110 is configured to perform step S22 in the following manner:
基于预设时长内所述患者的实时影像数据,获取所述预设时长内所述电极导线对应的多个位置数据;Based on the real-time image data of the patient within the preset time period, obtain multiple position data corresponding to the electrode leads within the preset time period;
基于所述多个位置数据,获取所述电极导线对应的实际路径;Based on the plurality of position data, obtain the actual path corresponding to the electrode lead;
利用路径相似度模型对所述电极导线对应的实际路径和参考路径进行相似度计算,得到所述电极导线对应的路径相似度;Use a path similarity model to calculate the similarity between the actual path corresponding to the electrode wire and the reference path to obtain the path similarity corresponding to the electrode wire;
基于所述电极导线对应的路径相似度,检测所述电极导线是否偏离其所对应的参考路径。Based on the path similarity corresponding to the electrode wire, it is detected whether the electrode wire deviates from its corresponding reference path.
在一些可选的实施例中,所述电极导线对应的参考路径的获取过程包括:In some optional embodiments, the process of obtaining the reference path corresponding to the electrode wire includes:
基于所述第一影像数据,获取所述电极导线对应的目标靶点的位姿信息; Based on the first image data, obtain the pose information of the target target corresponding to the electrode lead;
基于所述电极导线对应的目标靶点的位姿信息,获取所述电极导线对应的参考路径。Based on the pose information of the target point corresponding to the electrode lead, the reference path corresponding to the electrode lead is obtained.
在一些可选的实施例中,所述控制组件110被配置成采用如下方式获取所述电极导线对应的目标靶点的位姿信息:In some optional embodiments, the control component 110 is configured to obtain the pose information of the target target corresponding to the electrode lead in the following manner:
基于所述第一影像数据,生成所述患者的颅脑模型;Generate a brain model of the patient based on the first imaging data;
基于所述患者的颅脑模型,获取每个电极导线对应的目标靶点的位姿信息。Based on the patient's brain model, the pose information of the target target corresponding to each electrode lead is obtained.
本申请实施例还提供了一种手术机器人的控制系统,其实现方式与上述控制方法的实施例中记载的实施方式、所达到的技术效果一致,部分内容不再赘述。图6是本申请实施例提供的一种手术机器人的控制系统的结构框图。Embodiments of the present application also provide a control system for a surgical robot, the implementation manner of which is consistent with the implementation manner and technical effects achieved described in the embodiments of the above control method, and part of the content will not be described again. Figure 6 is a structural block diagram of a control system for a surgical robot provided by an embodiment of the present application.
所述系统被配置成控制手术机器人将未植入的每个电极导线植入患者颅内;The system is configured to control the surgical robot to implant each unimplanted electrode lead into the patient's skull;
所述系统包括:The system includes:
第一影像数据获取装置210,被配置成利用影像采集设备获取所述患者的第一影像数据;The first image data acquisition device 210 is configured to acquire the first image data of the patient using an image acquisition device;
驱动组件控制装置220,被配置成基于所述第一影像数据,控制所述手术机器人的驱动组件将所述电极导线植入所述患者的颅内;The driving component control device 220 is configured to control the driving component of the surgical robot to implant the electrode lead into the patient's skull based on the first image data;
第二影像数据获取装置230,被配置成利用所述影像采集设备获取所述患者的第二影像数据;The second image data acquisition device 230 is configured to acquire the second image data of the patient using the image acquisition device;
目标靶点检测装置240,被配置成基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移;The target target point detection device 240 is configured to detect whether the target target point corresponding to the electrode lead is offset based on the first image data and the second image data;
电极导线调整装置250,被配置成当检测到所述电极导线对应的目标靶点发生偏移时,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与其所对应的目标靶点相匹配。 The electrode lead adjustment device 250 is configured to control the driving assembly to adjust the posture of the electrode lead when it detects that the target target point corresponding to the electrode lead is offset, so that the position of the electrode lead is adjusted. The pose matches its corresponding target point.

Claims (11)

  1. 一种手术机器人,其中,所述手术机器人被配置成将至少两个电极导线植入患者颅内,所述手术机器人包括驱动组件以及控制组件;A surgical robot, wherein the surgical robot is configured to implant at least two electrode leads into the patient's skull, the surgical robot including a driving component and a control component;
    针对未植入的每个电极导线,所述控制组件被配置成执行:For each lead that is not implanted, the control component is configured to perform:
    利用影像采集设备获取所述患者的第一影像数据;Using an image acquisition device to obtain the first image data of the patient;
    基于所述第一影像数据,控制所述驱动组件将所述电极导线植入所述患者的颅内;Based on the first image data, control the driving component to implant the electrode lead into the patient's skull;
    利用所述影像采集设备获取所述患者的第二影像数据;Using the image acquisition device to obtain second image data of the patient;
    基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移;Based on the first image data and the second image data, detect whether the target target corresponding to the electrode lead is offset;
    在检测到所述电极导线对应的目标靶点发生偏移的情况下,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配。When it is detected that the target point corresponding to the electrode lead is offset, the driving component is controlled to adjust the posture of the electrode lead so that the posture of the electrode lead is consistent with the position of the electrode lead. The corresponding target targets match.
  2. 根据权利要求1所述的手术机器人,其中,所述控制组件被配置成采用如下方式基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移:The surgical robot according to claim 1, wherein the control component is configured to detect whether the target target point corresponding to the electrode lead is deflected based on the first image data and the second image data in the following manner: shift:
    获取每个目标靶点在所述第一影像数据中的第一边界框位置信息;Obtain the first bounding box position information of each target target in the first image data;
    获取每个目标靶点在所述第二影像数据中的第二边界框位置信息;Obtain the second bounding box position information of each target target in the second image data;
    基于每个目标靶点对应的第一边界框位置信息和第二边界框位置信息,检测所述电极导线对应的目标靶点是否发生偏移。Based on the first bounding box position information and the second bounding box position information corresponding to each target target point, it is detected whether the target target point corresponding to the electrode lead is offset.
  3. 根据权利要求2所述的手术机器人,其中,所述控制组件被配置成采用如下方式检测所述电极导线对应的目标靶点是否发生偏移:The surgical robot according to claim 2, wherein the control component is configured to detect whether the target target corresponding to the electrode lead is offset in the following manner:
    利用文本相似度模型对每个目标靶点对应的第一边界框位置信息和第二边界框位置信息进行相似度计算,得到每个目标靶点对应的位置相似度;Use the text similarity model to calculate the similarity of the first bounding box position information and the second bounding box position information corresponding to each target target, and obtain the position similarity corresponding to each target target;
    在所述电极导线对应的目标靶点对应的位置相似度小于第一相似度阈值的情况下,确定所述电极导线对应的目标靶点发生偏移。When the position similarity corresponding to the target point corresponding to the electrode lead is less than the first similarity threshold, it is determined that the target target point corresponding to the electrode lead is shifted.
  4. 根据权利要求2所述的手术机器人,其中,所述控制组件被配置成采用如下方式检测所述电极导线对应的目标靶点是否发生偏移:The surgical robot according to claim 2, wherein the control component is configured to detect whether the target target corresponding to the electrode lead is offset in the following manner:
    基于每个目标靶点对应的第一边界框位置信息,从所述第一影像数据中截取得到每个目标靶点对应的预设区域的第一子图像;Based on the first bounding box position information corresponding to each target target point, intercept the first sub-image of the preset area corresponding to each target target point from the first image data;
    基于每个目标靶点对应的第二边界框位置信息,从所述第二影像数据中截取得到每个目标靶点对应的预设区域的第二子图像; Based on the second bounding box position information corresponding to each target target point, intercept the second sub-image of the preset area corresponding to each target target point from the second image data;
    利用图像相似度模型对每个目标靶点对应的第一子图像和第二子图像进行相似度计算,得到每个目标靶点对应的图像相似度;Use the image similarity model to calculate the similarity of the first sub-image and the second sub-image corresponding to each target target, and obtain the image similarity corresponding to each target target;
    在所述电极导线对应的目标靶点对应的图像相似度小于第二相似度阈值的情况下,确定所述电极导线对应的目标靶点发生偏移。When the image similarity corresponding to the target point corresponding to the electrode lead is less than the second similarity threshold, it is determined that the target target point corresponding to the electrode lead is shifted.
  5. 根据权利要求1所述的手术机器人,其中,所述控制组件被配置成采用如下方式在检测到所述电极导线对应的目标靶点发生偏移的情况下,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配:The surgical robot according to claim 1, wherein the control component is configured to control the driving component to control the electrode when detecting a deviation of the target target corresponding to the electrode lead in the following manner: The posture of the lead is adjusted so that the posture of the electrode lead matches the target target corresponding to the electrode lead:
    在检测到所述电极导线对应的目标靶点发生偏移的情况下,控制所述驱动组件将所述电极导线向下深入或者向上提取,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配。When it is detected that the target target point corresponding to the electrode lead is offset, the driving assembly is controlled to deepen the electrode lead downward or extract it upward, so that the posture of the electrode lead is consistent with the electrode lead. The corresponding target targets match.
  6. 根据权利要求1所述的手术机器人,其中,所述控制组件被配置成采用如下方式在检测到所述电极导线对应的目标靶点发生偏移的情况下,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配:The surgical robot according to claim 1, wherein the control component is configured to control the driving component to control the electrode when detecting a deviation of the target target corresponding to the electrode lead in the following manner: The posture of the lead is adjusted so that the posture of the electrode lead matches the target target corresponding to the electrode lead:
    在检测到所述电极导线对应的目标靶点发生偏移的情况下,控制所述驱动组件将所述电极导线从所述患者的颅内移除,重新执行利用影像采集设备获取所述患者的第一影像数据,以控制所述驱动组件对所述电极导线进行位姿的调整。When it is detected that the target target corresponding to the electrode lead is shifted, the driving assembly is controlled to remove the electrode lead from the patient's skull, and the image acquisition device is used to obtain the patient's image again. The first image data is used to control the driving component to adjust the posture of the electrode lead.
  7. 根据权利要求1所述的手术机器人,其中,所述控制组件被配置成采用如下方式基于所述第一影像数据,控制所述驱动组件将所述电极导线植入所述患者的颅内:The surgical robot according to claim 1, wherein the control component is configured to control the driving component to implant the electrode lead into the patient's skull based on the first image data in the following manner:
    在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据;During the process of implanting the electrode lead using the driving assembly, the image acquisition device is used to obtain real-time image data of the patient;
    基于所述患者的实时影像数据,检测所述电极导线是否偏离所述电极导线所对应的参考路径;Based on the patient's real-time image data, detect whether the electrode lead deviates from the reference path corresponding to the electrode lead;
    在检测到所述电极导线未偏离所述电极导线所对应的参考路径的情况下,重新执行在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据;When it is detected that the electrode lead does not deviate from the reference path corresponding to the electrode lead, re-execute the process of using the driving assembly to implant the electrode lead and using the image acquisition device to acquire the patient real-time image data;
    在检测到所述电极导线偏离所述电极导线所对应的参考路径的情况下,基于所述患者的当前影像数据,更新所述电极导线对应的参考路径,重新执行在利用所述驱动组件植入所述电极导线的过程中,利用所述影像采集设备获取所述患者的实时影像数据。 When it is detected that the electrode lead deviates from the reference path corresponding to the electrode lead, the reference path corresponding to the electrode lead is updated based on the patient's current image data, and the implantation using the driving assembly is re-executed. During the process of conducting the electrode lead, the image acquisition device is used to obtain real-time image data of the patient.
  8. 根据权利要求7所述的手术机器人,其中,所述控制组件被配置成采用如下方式基于所述患者的实时影像数据,检测所述电极导线是否偏离所述电极导线所对应的参考路径:The surgical robot according to claim 7, wherein the control component is configured to detect whether the electrode lead deviates from the reference path corresponding to the electrode lead based on the patient's real-time image data in the following manner:
    基于预设时长内所述患者的实时影像数据,获取所述预设时长内所述电极导线对应的多个位置数据;Based on the real-time image data of the patient within the preset time period, obtain multiple position data corresponding to the electrode leads within the preset time period;
    基于所述多个位置数据,获取所述电极导线对应的实际路径;Based on the plurality of position data, obtain the actual path corresponding to the electrode lead;
    利用路径相似度模型对所述电极导线对应的实际路径和参考路径进行相似度计算,得到所述电极导线对应的路径相似度;Use a path similarity model to calculate the similarity between the actual path corresponding to the electrode wire and the reference path to obtain the path similarity corresponding to the electrode wire;
    基于所述电极导线对应的路径相似度,检测所述电极导线是否偏离所述电极导线所对应的参考路径。Based on the path similarity corresponding to the electrode wire, it is detected whether the electrode wire deviates from the reference path corresponding to the electrode wire.
  9. 根据权利要求7或8任一项所述的手术机器人,其中,所述控制组件被配置成采用如下方式获取所述电极导线对应的参考路径包括:The surgical robot according to any one of claims 7 or 8, wherein the control component is configured to obtain the reference path corresponding to the electrode lead in the following manner:
    基于所述第一影像数据,获取所述电极导线对应的目标靶点的位姿信息;Based on the first image data, obtain the pose information of the target target corresponding to the electrode lead;
    基于所述电极导线对应的目标靶点的位姿信息,获取所述电极导线对应的参考路径。Based on the pose information of the target point corresponding to the electrode lead, the reference path corresponding to the electrode lead is obtained.
  10. 根据权利要求9所述的手术机器人,其中,所述控制组件被配置成采用如下方式获取所述电极导线对应的目标靶点的位姿信息:The surgical robot according to claim 9, wherein the control component is configured to obtain the pose information of the target target corresponding to the electrode lead in the following manner:
    基于所述第一影像数据,生成所述患者的颅脑模型;Generate a brain model of the patient based on the first imaging data;
    基于所述患者的颅脑模型,获取每个电极导线对应的目标靶点的位姿信息。Based on the patient's brain model, the pose information of the target target corresponding to each electrode lead is obtained.
  11. 一种手术机器人的控制系统,被配置成控制手术机器人将未植入的每个电极导线植入患者颅内;A control system for a surgical robot configured to control the surgical robot to implant each unimplanted electrode lead into the patient's skull;
    所述系统包括:The system includes:
    第一影像数据获取装置,被配置成利用影像采集设备获取所述患者的第一影像数据;A first image data acquisition device configured to acquire first image data of the patient using an image acquisition device;
    驱动组件控制装置,被配置成基于所述第一影像数据,控制所述手术机器人的驱动组件将所述电极导线植入所述患者的颅内;a driving component control device configured to control the driving component of the surgical robot to implant the electrode lead into the patient's skull based on the first image data;
    第二影像数据获取装置,被配置成利用所述影像采集设备获取所述患者的第二影像数据;a second image data acquisition device configured to acquire second image data of the patient using the image acquisition device;
    目标靶点检测装置,被配置成基于所述第一影像数据和所述第二影像数据,检测所述电极导线对应的目标靶点是否发生偏移;A target target point detection device configured to detect whether the target target point corresponding to the electrode lead is offset based on the first image data and the second image data;
    电极导线调整装置,被配置成在检测到所述电极导线对应的目标靶点发生 偏移的情况下,控制所述驱动组件对所述电极导线进行位姿的调整,以使所述电极导线的位姿与所述电极导线所对应的目标靶点相匹配。 The electrode lead adjustment device is configured to detect an occurrence of a target point corresponding to the electrode lead. In the case of offset, the driving assembly is controlled to adjust the posture of the electrode lead so that the posture of the electrode lead matches the target target point corresponding to the electrode lead.
PCT/CN2023/089533 2022-04-27 2023-04-20 Surgical robot and control system therefor WO2023207752A1 (en)

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