WO2023197924A1 - Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method - Google Patents

Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method Download PDF

Info

Publication number
WO2023197924A1
WO2023197924A1 PCT/CN2023/086501 CN2023086501W WO2023197924A1 WO 2023197924 A1 WO2023197924 A1 WO 2023197924A1 CN 2023086501 W CN2023086501 W CN 2023086501W WO 2023197924 A1 WO2023197924 A1 WO 2023197924A1
Authority
WO
WIPO (PCT)
Prior art keywords
segment
arc
dimensional
line
cobb angle
Prior art date
Application number
PCT/CN2023/086501
Other languages
French (fr)
Chinese (zh)
Inventor
杨雷
颜滨
李柳旬
Original Assignee
深圳市第二人民医院(深圳市转化医学研究院)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市第二人民医院(深圳市转化医学研究院) filed Critical 深圳市第二人民医院(深圳市转化医学研究院)
Publication of WO2023197924A1 publication Critical patent/WO2023197924A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data

Definitions

  • the invention belongs to the technical field of scoliosis diagnosis and screening, and in particular relates to an intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound.
  • Adolescent Idiopathic scoliosis is a disabling and fatal deformity.
  • the literature reports that its incidence rate is 2% to 4%. It mostly occurs in primary and secondary school students in adolescence.
  • the main manifestations are X-ray Abnormal three-dimensional structure of the spine with scoliosis Cobb angle ⁇ 10° on plain radiographs.
  • the number of scoliosis among primary and secondary school students in my country has exceeded 5 million, and the number is increasing at a rate of 300,000 per year. Therefore, timely screening, accurate assessment and effective monitoring of patients with adolescent idiopathic scoliosis can help clarify the condition and take appropriate treatment measures to prevent the condition from worsening, thereby reducing the risk of surgical intervention.
  • X-ray is currently the most commonly used imaging mode to diagnose scoliosis (scoliosis) and track its development.
  • X-ray imaging involves radiation damage, and it is difficult for two-dimensional X-ray images to fully reflect the three-dimensional deformity characteristics.
  • the Cobb angle of scoliosis has a very important impact on the diagnosis and subsequent treatment of scoliosis.
  • the measurement of the Cobb angle is usually performed by imaging experts to manually determine the upper and lower degrees of scoliosis after obtaining X-ray images. After distal vertebrae, use a protractor to measure the angle between the two terminal vertebrae.
  • this method exposes the patient to X-ray radiation and will cause varying degrees of harm to the patient.
  • scoliosis patients also need to X-rays are taken multiple times, so this method can cause greater harm to teenage patients.
  • the purpose of the present invention is to provide an intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound.
  • the Cobb angle measurement method of the present invention collects three-dimensional information of the patient's spine by using three-dimensional ultrasound. , and after analysis by the computer, the two intersecting lines of the Cobb angle are automatically marked, and the Cobb angle is then measured.
  • An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound including the following steps:
  • step S2 Input the three-dimensional spine image obtained in step S1 into the computer system, and display, process and analyze the image information through the computer system;
  • the computer system identifies and extracts all spinous processes in the three-dimensional spine image, generates corresponding marker points, and then connects all the marker points to form a spinous process connection line.
  • the spinous process connection line consists of a straight line segment and an arc. It consists of a line segment and a lower straight line segment. At the transition point between the upper straight line segment and the arc line segment, draw the tangent line L1 of the arc segment. At the transition point between the lower straight line segment and the arc line segment, draw the tangent line L2 of the arc segment.
  • the tangent line L1 and the tangent line The angle ⁇ formed by L2 is the Cobb angle.
  • step S3 if the line connecting the spinous processes consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment, then the Cobb angle needs to be measured for the two arc line segments respectively, that is: the upper and lower sides
  • the arc segments are respectively set as the first arc segment and the second arc segment.
  • the transition point of the arc segment is the tangent L2 of the first arc segment.
  • the angle ⁇ formed by the tangent L1 and the tangent L2 is the Cobb angle of the first arc segment.
  • the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
  • the computer system is configured with a storage module, a display module, an output report module and a processor.
  • the storage module is used to store three-dimensional spine image information and Cobb angle data information.
  • the processor is used to analyze and process the three-dimensional ultrasound image information, and through The display module performs display, and the output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
  • the present invention has the following beneficial effects:
  • the Cobb angle measurement method of the present invention uses a three-dimensional ultrasound system to collect the three-dimensional information of the patient's spine. It only needs to use an ultrasound probe to scan the patient's back to collect the spine information, which has the advantages of high efficiency and safety;
  • the present invention identifies and extracts the spinous processes on the three-dimensional image of the spine and generates a spinous process connection line. Corresponding tangent lines are drawn at both ends of the curved part on the spinous process connection line. The angle between the tangent lines is the Cobb angle. Using this method The Cobb angle measured by the invented measurement method is extremely accurate and has strong applicability. As long as there is a three-dimensional ultrasound image of the spine, the Cobb angle can be measured through the computer system to determine whether there is spinal deformity and evaluate its severity, and finally give Risk reporting and medical advice.
  • Figure 1 is a schematic diagram of measuring the Cobb angle of a single bend on the line connecting the spinous processes on the back of the human body;
  • Figure 2 is a schematic diagram of measuring the double-bent Cobb angle on the line connecting the spinous processes on the back of the human body;
  • A upper straight line segment
  • B lower straight line segment
  • C arc segment
  • C1 first arc segment
  • C2 second arc segment
  • D U
  • S transition points
  • L1, L2 Tangent line
  • L line connecting spinous processes
  • ⁇ , ⁇ 1, ⁇ 2 Cobb angle.
  • An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound including the following steps:
  • step S2 Input the three-dimensional spine image obtained in step S1 into the computer system, and display, process and analyze the image information through the computer system;
  • spinous process connection line L consists of an upper straight line segment A, an arc line segment C and a lower straight line segment B.
  • the upper straight line segment A and the circle At the transition point U of arc segment C, draw the tangent line L1 of the arc segment.
  • draw the tangent line L2 of the arc segment At the transition point D between the lower straight line segment B and the arc segment C, draw the tangent line L2 of the arc segment.
  • the angle ⁇ formed by the tangent line L1 and the tangent line L2 is is the Cobb angle.
  • step S3 if the spinous process connection line L consists of an upper straight line segment A, two continuous arc line segments and a lower straight line segment B, then the Cobb angle needs to be measured for the two arc line segments respectively, that is, the upper and lower sides
  • the arc segments are respectively set as the first arc segment C1 and the second arc segment C2.
  • the transition point D between the arc segment C1 and the second arc segment C2 is the tangent line L2 of the first arc segment C1.
  • the angle ⁇ 1 formed by the tangent line L1 and the tangent line L2 is the Cobb angle of the first arc segment C1.
  • the transition point S between the second arc segment C2 and the lower straight line segment B is the tangent line L3 of the second arc segment C2.
  • the angle ⁇ 2 formed by the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
  • the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
  • the computer system is configured with a storage module, a display module, an output report module and a processor.
  • the storage module is used to store three-dimensional spine image information and Cobb angle data information.
  • the processor is used to analyze and process three-dimensional ultrasound image information, and perform processing through the display module.
  • the display and output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
  • step S3 of the present invention the line connecting the spinous processes of a normal person is a straight line when viewed from the back of the human body.
  • the spinous processes of scoliosis patients will shift or rotate the vertebral bodies, resulting in the position of the spinous processes. Changes occur.
  • the line connecting the spinous processes will form a curve (called a "single bend"), that is, a single lumbar curve or a single thoracic curve, or two curves will be formed on the line connecting the spinous processes (called a "single bend").
  • the spinous process connection line consists of an upper straight line segment, an arc line segment and a lower straight line segment.
  • the tangent line L1 of the arc line segment is drawn, and between the lower straight line segment and the arc segment
  • the tangent line L2 of the arc segment is made at the transition point of the line segment.
  • the angle ⁇ formed by the tangent line L1 and the tangent line L2 is the Cobb angle.
  • the spinous process connection line consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment. It is necessary to measure the Cobb angle of the two arc line segments separately, that is, set the upper and lower arc line segments as the first For the arc segment and the second arc segment, draw the tangent line L1 of the arc segment at the transition point between the upper straight line segment and the first arc segment, and draw the third arc segment at the transition point between the first arc segment and the second arc segment.
  • the angle ⁇ formed by the tangent line L2 of a circular arc segment, the tangent line L1 and the tangent line L2 is the Cobb angle of the first circular arc segment.
  • the second circular arc segment is drawn at the transition point between the second circular arc segment and the lower straight line segment.
  • the angle ⁇ formed by the tangent line L3, the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
  • the measurement method of the Cobb angle is the same as the measurement method of the above-mentioned double bends. You only need to draw the tangent line at the transition point of the adjacent arc segment. You can get the Cobb angle.

Abstract

A three-dimensional-ultrasound-based intelligent scoliosis Cobb angle measuring method, belonging to the technical field of scoliosis diagnosing and screening and comprising the following steps: S1, using a three-dimensional ultrasonic system to acquire three-dimensional ultrasonic image information of the spine to form a three-dimensional spine image; S2, inputting the three-dimensional spine image obtained in step S1 into a computer system, and by means of the computer system, displaying, processing and analyzing the image information; and S3, the computer system identifying and extracting all spinous processes in the three-dimensional spine image and generating corresponding mark points, and then connecting all the mark points to form a spinous process connecting line, which consists of an upper straight line segment, an arc line segment and a lower straight line segment, making tangent L1 of the arc line segment at a transition point of the upper straight line segment and the arc line segment, and making tangent L2 of the arc line segment at a transition point of the lower straight line segment and the arc line segment. The angle α formed between tangent L1 and tangent L2 is a Cobb angle.

Description

一种基于三维超声的智能化脊柱侧弯Cobb角测量方法An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound
本申请要求于2022年04月14日提交中国专利局、申请号为202210390096.1、发明名称为“一种基于三维超声的智能化脊柱侧弯Cobb角测量方法”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。This application requests the priority of the Chinese patent application submitted to the China Patent Office on April 14, 2022, with the application number 202210390096.1 and the invention title "An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound", all of which The contents are incorporated into this application by reference.
技术领域Technical field
本发明属于脊柱侧弯诊断和筛查技术领域，尤其涉及一种基于三维超声的智能化脊柱侧弯Cobb角测量方法。The invention belongs to the technical field of scoliosis diagnosis and screening, and in particular relates to an intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound.
背景技术Background technique
青少年特发性脊柱侧凸(Adolescent Idiopathic scoliosis，AIS)是一种致残性、致死性畸形，文献报道其发病率为2％～4％，好发于青春期的中小学生，主要表现为X线平片上脊柱侧凸Cobb角≥10°的脊柱三维结构异常。根据中华预防医学会流调数据，目前我国中小学生发生脊柱侧弯人数已经超过500万人，并以每年30万的速度递增。因此，对青少年特发性脊柱侧弯患者的及时筛查，精确评估和有效监测，可以帮助明确病情和采取适宜治疗措施防止病情恶化，从而减轻手术干预风险。Adolescent Idiopathic scoliosis (AIS) is a disabling and fatal deformity. The literature reports that its incidence rate is 2% to 4%. It mostly occurs in primary and secondary school students in adolescence. The main manifestations are X-ray Abnormal three-dimensional structure of the spine with scoliosis Cobb angle ≥10° on plain radiographs. According to statistics from the Chinese Association of Preventive Medicine, the number of scoliosis among primary and secondary school students in my country has exceeded 5 million, and the number is increasing at a rate of 300,000 per year. Therefore, timely screening, accurate assessment and effective monitoring of patients with adolescent idiopathic scoliosis can help clarify the condition and take appropriate treatment measures to prevent the condition from worsening, thereby reducing the risk of surgical intervention.
目前X线是诊断脊柱侧凸(脊柱侧弯)并跟踪其发展状态的最常用成像模式，但X线成像存在辐射伤害,而且二维X线图像难以全面反映三维畸形特征。脊柱侧弯Cobb角对于脊柱侧弯的诊断以及后续的治疗有着很重要的影响，而目前，对于Cobb角的测量，通常是采用获取X线片图像以后，经影像专家手动确立脊柱侧弯的上下端椎后，使用量角器量取出两终端之间夹角，但是这种方法使得患者受到X线的辐射，对患者会造成不同程度的伤害，而且，脊柱侧弯患者在后续治疗过程中，还需要多次拍X光片，因此，这种方法会对青少年患者造成较大的伤害。X-ray is currently the most commonly used imaging mode to diagnose scoliosis (scoliosis) and track its development. However, X-ray imaging involves radiation damage, and it is difficult for two-dimensional X-ray images to fully reflect the three-dimensional deformity characteristics. The Cobb angle of scoliosis has a very important impact on the diagnosis and subsequent treatment of scoliosis. At present, the measurement of the Cobb angle is usually performed by imaging experts to manually determine the upper and lower degrees of scoliosis after obtaining X-ray images. After distal vertebrae, use a protractor to measure the angle between the two terminal vertebrae. However, this method exposes the patient to X-ray radiation and will cause varying degrees of harm to the patient. Moreover, scoliosis patients also need to X-rays are taken multiple times, so this method can cause greater harm to teenage patients.
发明内容Contents of the invention
为了解决现有技术中存在的问题，本发明的目的是提供一种基于三维超声的智能化脊柱侧弯Cobb角测量方法，本发明的Cobb角测量方法通过采用三维超声来采集患者的脊柱三维信息，并通过计算机进行分析后自动标记出Cobb角的两条相交线，进而测量出Cobb角。In order to solve the problems existing in the prior art, the purpose of the present invention is to provide an intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound. The Cobb angle measurement method of the present invention collects three-dimensional information of the patient's spine by using three-dimensional ultrasound. , and after analysis by the computer, the two intersecting lines of the Cobb angle are automatically marked, and the Cobb angle is then measured.
为了实现上述发明目的，本发明采用如下所述的技术方案：In order to achieve the above-mentioned object of the invention, the present invention adopts the following technical solutions:
一种基于三维超声的智能化脊柱侧弯Cobb角测量方法，包括以下步骤：An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound, including the following steps:
S1、利用三维超声系统采集脊柱的三维超声图像信息，形成三维脊柱图像；S1. Use the three-dimensional ultrasound system to collect three-dimensional ultrasound image information of the spine to form a three-dimensional spine image;
S2、将步骤S1中获得的三维脊柱图像输入到计算机系统中，通过计算机系统对图像信息进行显示、处理和分析；S2. Input the three-dimensional spine image obtained in step S1 into the computer system, and display, process and analyze the image information through the computer system;
S3、计算机系统对三维脊柱图像中的所有棘突进行识别提取，并生成对应的标记点，然后将所有标记点进行连线，形成棘突连线，棘突连线由上直线段、圆弧线段和下直线段构成，在上直线段与圆弧线段的过渡点处做圆弧线段的切线L1，在下直线段与圆弧线段的过渡点处做圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为Cobb角。S3. The computer system identifies and extracts all spinous processes in the three-dimensional spine image, generates corresponding marker points, and then connects all the marker points to form a spinous process connection line. The spinous process connection line consists of a straight line segment and an arc. It consists of a line segment and a lower straight line segment. At the transition point between the upper straight line segment and the arc line segment, draw the tangent line L1 of the arc segment. At the transition point between the lower straight line segment and the arc line segment, draw the tangent line L2 of the arc segment. The tangent line L1 and the tangent line The angle α formed by L2 is the Cobb angle.
进一步的，在步骤S3中，若棘突连线由上直线段、两段连续的圆弧线段和下直线段构成，则需要对两段圆弧线段分别测量Cobb角，即：将上下侧两段圆弧线段分别设为第一圆弧线段和第二圆弧线段，在上直线段与第一圆弧线段的过渡点处做圆弧线段的切线L1，在第一圆弧线段与第二圆弧线段的过渡点处做第一圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为第一圆弧段的Cobb角，在第二圆弧线段与下直线段的过渡点处做第二圆弧线段的切线L3，切线L2和切线L3形成的夹角α即为第二圆弧段的Cobb角。Further, in step S3, if the line connecting the spinous processes consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment, then the Cobb angle needs to be measured for the two arc line segments respectively, that is: the upper and lower sides The arc segments are respectively set as the first arc segment and the second arc segment. Make the tangent line L1 of the arc segment at the transition point between the upper straight line segment and the first arc segment. Between the first arc segment and the second arc segment, The transition point of the arc segment is the tangent L2 of the first arc segment. The angle α formed by the tangent L1 and the tangent L2 is the Cobb angle of the first arc segment. At the transition between the second arc segment and the lower straight line segment Make the tangent line L3 of the second arc segment at the point, and the angle α formed by the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
进一步的，三维超声系统为多普勒超声诊断仪。Further, the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
进一步的，所述计算机系统配置有存储模块、显示模块、输出报告模块和处理器，存储模块用于储存三维脊柱图像信息以及Cobb角数据信息，处理器用于分析和处理三维超声图像信息，并通过显示模块进行显示，输出报告模块用于将经过处理器处理后的Cobb角数据信息以报告形式输出。 Further, the computer system is configured with a storage module, a display module, an output report module and a processor. The storage module is used to store three-dimensional spine image information and Cobb angle data information. The processor is used to analyze and process the three-dimensional ultrasound image information, and through The display module performs display, and the output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
由于采用上述技术方案，本发明具有以下有益效果：Due to the adoption of the above technical solutions, the present invention has the following beneficial effects:
1、本发明的Cobb角测量方法通过采用三维超声系统来采集患者的脊柱三维信息，只需要利用超声探头来扫描患者背部即可实现脊柱信息的采集，具有高效、安全的优点；1. The Cobb angle measurement method of the present invention uses a three-dimensional ultrasound system to collect the three-dimensional information of the patient's spine. It only needs to use an ultrasound probe to scan the patient's back to collect the spine information, which has the advantages of high efficiency and safety;
2、本发明对脊柱三位图像上面的棘突进行识别提取并生成棘突连线，在棘突连线上的弯曲部分两端分别对应画出切线，切线夹角即为Cobb角,采用本发明的测量方法测量出的Cobb角极为准确，而且适用性较强，只要有脊柱的三维超声影像即可通过计算机系统测量出Cobb角，进而判别是否存在脊柱畸形并评价其严重程度，最终给出风险报告及医疗建议。2. The present invention identifies and extracts the spinous processes on the three-dimensional image of the spine and generates a spinous process connection line. Corresponding tangent lines are drawn at both ends of the curved part on the spinous process connection line. The angle between the tangent lines is the Cobb angle. Using this method The Cobb angle measured by the invented measurement method is extremely accurate and has strong applicability. As long as there is a three-dimensional ultrasound image of the spine, the Cobb angle can be measured through the computer system to determine whether there is spinal deformity and evaluate its severity, and finally give Risk reporting and medical advice.
附图说明Description of the drawings
图1为人体背面的棘突连线上单弯的Cobb角测量示意图；Figure 1 is a schematic diagram of measuring the Cobb angle of a single bend on the line connecting the spinous processes on the back of the human body;
图2为人体背面的棘突连线上双弯的Cobb角测量示意图；Figure 2 is a schematic diagram of measuring the double-bent Cobb angle on the line connecting the spinous processes on the back of the human body;
图中：A：上直线段；B：下直线段；C：圆弧线段；C1：第一圆弧线段；C2：第二圆弧线段；D、U、S：过渡点；L1、L2：切线；L：棘突连线；α、α1、α2：Cobb角。In the figure: A: upper straight line segment; B: lower straight line segment; C: arc segment; C1: first arc segment; C2: second arc segment; D, U, S: transition points; L1, L2: Tangent line; L: line connecting spinous processes; α, α1, α2: Cobb angle.
具体实施方式Detailed ways
下面结合附图及实施例对本发明的技术方案做进一步详细的说明。The technical solution of the present invention will be further described in detail below with reference to the accompanying drawings and examples.
一种基于三维超声的智能化脊柱侧弯Cobb角测量方法，包括以下步骤：An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound, including the following steps:
S1、利用三维超声系统采集脊柱的三维超声图像信息，形成三维脊柱图像；S1. Use the three-dimensional ultrasound system to collect three-dimensional ultrasound image information of the spine to form a three-dimensional spine image;
S2、将步骤S1中获得的三维脊柱图像输入到计算机系统中，通过计算机系统对图像信息进行显示、处理和分析；S2. Input the three-dimensional spine image obtained in step S1 into the computer system, and display, process and analyze the image information through the computer system;
S3、计算机系统对三维脊柱图像中的所有棘突进行识别提取，并生成对应的标记点，然后将所有标记点进行连线，形成棘突连线L，如图1所示，棘突连线L由上直线段A、圆弧线段C和下直线段B构成，在上直线段A与圆 弧线段C的过渡点U处做圆弧线段的切线L1，在下直线段B与圆弧线段C的过渡点D处做圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为Cobb角。S3. The computer system identifies and extracts all spinous processes in the three-dimensional spine image, generates corresponding marker points, and then connects all the marker points to form a spinous process connection line L, as shown in Figure 1, spinous process connection line L consists of an upper straight line segment A, an arc line segment C and a lower straight line segment B. The upper straight line segment A and the circle At the transition point U of arc segment C, draw the tangent line L1 of the arc segment. At the transition point D between the lower straight line segment B and the arc segment C, draw the tangent line L2 of the arc segment. The angle α formed by the tangent line L1 and the tangent line L2 is is the Cobb angle.
在步骤S3中，若棘突连线L由上直线段A、两段连续的圆弧线段和下直线段B构成，则需要对两段圆弧线段分别测量Cobb角，即：将上下侧两段圆弧线段分别设为第一圆弧线段C1和第二圆弧线段C2，在上直线段A与第一圆弧线段C1的过渡点U处做圆弧线段的切线L1，在第一圆弧线段C1与第二圆弧线段C2的过渡点D处做第一圆弧线段C1的切线L2，切线L1和切线L2形成的夹角α1即为第一圆弧段C1的Cobb角，在第二圆弧线段C2与下直线段B的过渡点S处做第二圆弧线段C2的切线L3，切线L2和切线L3形成的夹角α2即为第二圆弧段的Cobb角。In step S3, if the spinous process connection line L consists of an upper straight line segment A, two continuous arc line segments and a lower straight line segment B, then the Cobb angle needs to be measured for the two arc line segments respectively, that is, the upper and lower sides The arc segments are respectively set as the first arc segment C1 and the second arc segment C2. Draw the tangent line L1 of the arc segment at the transition point U between the upper straight line segment A and the first arc segment C1. The transition point D between the arc segment C1 and the second arc segment C2 is the tangent line L2 of the first arc segment C1. The angle α1 formed by the tangent line L1 and the tangent line L2 is the Cobb angle of the first arc segment C1. The transition point S between the second arc segment C2 and the lower straight line segment B is the tangent line L3 of the second arc segment C2. The angle α2 formed by the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
在本发明中，所述的三维超声系统为多普勒超声诊断仪。In the present invention, the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
所述计算机系统配置有存储模块、显示模块、输出报告模块和处理器，存储模块用于储存三维脊柱图像信息以及Cobb角数据信息，处理器用于分析和处理三维超声图像信息，并通过显示模块进行显示，输出报告模块用于将经过处理器处理后的Cobb角数据信息以报告形式输出。The computer system is configured with a storage module, a display module, an output report module and a processor. The storage module is used to store three-dimensional spine image information and Cobb angle data information. The processor is used to analyze and process three-dimensional ultrasound image information, and perform processing through the display module. The display and output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
在本发明的步骤S3中，正常人的棘突连线在人体背面看是一条直线，但是脊柱侧弯病人的棘突由于脊柱侧弯畸形，椎体会发生偏移或旋转，导致棘突位置发生改变，此时在人体背面看，棘突连线会形成一个弯曲(称为“单弯”)，即单腰弯或单胸弯，或是在棘突连线上形成两个弯曲(称为“双弯”)，即腰弯和胸弯，甚至棘突连线上会形成两个以上的弯曲，而弯曲部分即为需要测量的脊柱侧弯Cobb角所在位置。In step S3 of the present invention, the line connecting the spinous processes of a normal person is a straight line when viewed from the back of the human body. However, due to scoliosis deformity, the spinous processes of scoliosis patients will shift or rotate the vertebral bodies, resulting in the position of the spinous processes. Changes occur. At this time, when viewed from the back of the human body, the line connecting the spinous processes will form a curve (called a "single bend"), that is, a single lumbar curve or a single thoracic curve, or two curves will be formed on the line connecting the spinous processes (called a "single bend"). It is a "double curve"), that is, the lumbar curve and the thoracic curve, or even more than two curves will be formed on the line connecting the spinous processes, and the curved part is the location of the scoliosis Cobb angle that needs to be measured.
以单弯(即单腰弯或单胸弯)为例，测量脊柱侧弯Cobb角：Taking a single curve (that is, a single lumbar curve or a single thoracic curve) as an example, measure the scoliosis Cobb angle:
如图1所示，棘突连线由上直线段、圆弧线段和下直线段构成，在上直线段与圆弧线段的过渡点处做圆弧线段的切线L1，在下直线段与圆弧线段的过渡点处做圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为Cobb角。As shown in Figure 1, the spinous process connection line consists of an upper straight line segment, an arc line segment and a lower straight line segment. At the transition point between the upper straight line segment and the arc line segment, the tangent line L1 of the arc line segment is drawn, and between the lower straight line segment and the arc segment The tangent line L2 of the arc segment is made at the transition point of the line segment. The angle α formed by the tangent line L1 and the tangent line L2 is the Cobb angle.
以双弯(即胸弯和腰弯)为例，测量脊柱侧弯Cobb角，如下所述： Taking double curves (i.e. thoracic curve and lumbar curve) as an example, measure the scoliosis Cobb angle as follows:
由于是胸弯和腰弯双弯，那么棘突连线上存在两个圆弧线段，上面的圆弧线段为胸弯，下面的圆弧线段为腰弯，两个弯曲均为需要测量脊柱侧弯Cobb角的所在位置。Since it is a double curve of thoracic and lumbar curves, there are two arc segments on the line connecting the spinous processes. The upper arc segment is the thoracic curve, and the lower arc segment is the lumbar curve. Both curves need to be measured on the side of the spine. The location of the Cobb corner.
棘突连线由上直线段、两段连续的圆弧线段和下直线段构成，则需要对两段圆弧线段分别测量Cobb角，即：将上下侧两段圆弧线段分别设为第一圆弧线段和第二圆弧线段，在上直线段与第一圆弧线段的过渡点处做圆弧线段的切线L1，在第一圆弧线段与第二圆弧线段的过渡点处做第一圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为第一圆弧段的Cobb角，在第二圆弧线段与下直线段的过渡点处做第二圆弧线段的切线L3，切线L2和切线L3形成的夹角α即为第二圆弧段的Cobb角。The spinous process connection line consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment. It is necessary to measure the Cobb angle of the two arc line segments separately, that is, set the upper and lower arc line segments as the first For the arc segment and the second arc segment, draw the tangent line L1 of the arc segment at the transition point between the upper straight line segment and the first arc segment, and draw the third arc segment at the transition point between the first arc segment and the second arc segment. The angle α formed by the tangent line L2 of a circular arc segment, the tangent line L1 and the tangent line L2 is the Cobb angle of the first circular arc segment. The second circular arc segment is drawn at the transition point between the second circular arc segment and the lower straight line segment. The angle α formed by the tangent line L3, the tangent line L2 and the tangent line L3 is the Cobb angle of the second arc segment.
另外，需要说明的是，若棘突连线上存在两个以上的弯曲，则Cobb角的测量方法与上述双弯的测量方法相同，只需要将相邻圆弧线段过渡点处的切线做出即可得出Cobb角。 In addition, it should be noted that if there are more than two bends on the line connecting the spinous processes, the measurement method of the Cobb angle is the same as the measurement method of the above-mentioned double bends. You only need to draw the tangent line at the transition point of the adjacent arc segment. You can get the Cobb angle.

Claims (4)

  1. 一种基于三维超声的智能化脊柱侧弯Cobb角测量方法，其特征在于，包括以下步骤：An intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound, which is characterized by including the following steps:
    S1、利用三维超声系统采集脊柱的三维超声图像信息，形成三维脊柱图像；S1. Use the three-dimensional ultrasound system to collect three-dimensional ultrasound image information of the spine to form a three-dimensional spine image;
    S2、将步骤S1中获得的三维脊柱图像输入到计算机系统中，通过计算机系统对图像信息进行显示、处理和分析；S2. Input the three-dimensional spine image obtained in step S1 into the computer system, and display, process and analyze the image information through the computer system;
    S3、计算机系统对三维脊柱图像中的所有棘突进行识别提取，并生成对应的标记点，然后将所有标记点进行连线，形成棘突连线，棘突连线由上直线段、圆弧线段和下直线段构成，在上直线段与圆弧线段的过渡点处做圆弧线段的切线L1，在下直线段与圆弧线段的过渡点处做圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为Cobb角。S3. The computer system identifies and extracts all spinous processes in the three-dimensional spine image, generates corresponding marker points, and then connects all the marker points to form a spinous process connection line. The spinous process connection line consists of a straight line segment and an arc. It consists of a line segment and a lower straight line segment. At the transition point between the upper straight line segment and the arc line segment, draw the tangent line L1 of the arc segment. At the transition point between the lower straight line segment and the arc line segment, draw the tangent line L2 of the arc segment. The tangent line L1 and the tangent line The angle α formed by L2 is the Cobb angle.
  2. 根据权利要求1所述的基于三维超声的智能化脊柱侧弯Cobb角测量方法，其特征在于，在步骤S3中，若棘突连线由上直线段、两段连续的圆弧线段和下直线段构成，则需要对两段圆弧线段分别测量Cobb角，即：将上下侧两段圆弧线段分别设为第一圆弧线段和第二圆弧线段，在上直线段与第一圆弧线段的过渡点处做圆弧线段的切线L1，在第一圆弧线段与第二圆弧线段的过渡点处做第一圆弧线段的切线L2，切线L1和切线L2形成的夹角α即为第一圆弧段的Cobb角，在第二圆弧线段与下直线段的过渡点处做第二圆弧线段的切线L3，切线L2和切线L3形成的夹角α即为第二圆弧段的Cobb角。The intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound according to claim 1, characterized in that, in step S3, if the spinous process connection line consists of an upper straight line segment, two continuous arc line segments and a lower straight line segment, you need to measure the Cobb angle of the two arc segments respectively, that is: set the two arc segments on the upper and lower sides as the first arc segment and the second arc segment respectively, between the upper straight segment and the first arc segment Make the tangent line L1 of the arc segment at the transition point of the line segment, and draw the tangent line L2 of the first arc segment at the transition point of the first arc segment and the second arc segment. The angle α formed by the tangent line L1 and the tangent line L2 is is the Cobb angle of the first arc segment. Draw the tangent line L3 of the second arc segment at the transition point between the second arc segment and the lower straight line segment. The angle α formed by the tangent line L2 and the tangent line L3 is the second arc segment. Cobb angle of the segment.
  3. 根据权利要求1所述的基于三维超声的智能化脊柱侧弯Cobb角测量方法，其特征在于，三维超声系统为多普勒超声诊断仪。The intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound according to claim 1, characterized in that the three-dimensional ultrasound system is a Doppler ultrasound diagnostic instrument.
  4. 根据权利要求1所述的基于三维超声的智能化脊柱侧弯Cobb角测量方法，其特征在于，所述计算机系统配置有存储模块、显示模块、输出报告模块和处理器，存储模块用于储存三维脊柱图像信息以及Cobb角数据信息，处理器用于分析和处理三维超声图像信息，并通过显示模块进行显示，输出报告模块用于将经过处理器处理后的Cobb角数据信息以报告形式输出。 The intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound according to claim 1, characterized in that the computer system is configured with a storage module, a display module, an output report module and a processor, and the storage module is used to store three-dimensional The processor is used to analyze and process the three-dimensional ultrasound image information and display the spine image information and Cobb angle data information through the display module. The output report module is used to output the Cobb angle data information processed by the processor in the form of a report.
PCT/CN2023/086501 2022-04-14 2023-04-06 Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method WO2023197924A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202210390096.1A CN114903518A (en) 2022-04-14 2022-04-14 Intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound
CN202210390096.1 2022-04-14

Publications (1)

Publication Number Publication Date
WO2023197924A1 true WO2023197924A1 (en) 2023-10-19

Family

ID=82765385

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2023/086501 WO2023197924A1 (en) 2022-04-14 2023-04-06 Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method

Country Status (2)

Country Link
CN (1) CN114903518A (en)
WO (1) WO2023197924A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114903518A (en) * 2022-04-14 2022-08-16 深圳市第二人民医院(深圳市转化医学研究院) Intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101917918A (en) * 2007-10-30 2010-12-15 埃利普斯科技有限公司 Skeletal manipulation system
CN106725500A (en) * 2017-01-17 2017-05-31 上海脊光医疗科技有限公司 Functional spinal measurement apparatus
CN107595387A (en) * 2017-07-28 2018-01-19 浙江大学 A kind of vertebra image generation system and spinal operation navigation positioning system based on ultrasonic rubbing technology
CN109223032A (en) * 2017-07-11 2019-01-18 中慧医学成像有限公司 A kind of method of 3-D supersonic imaging detection deformation of spinal column
US20200121279A1 (en) * 2016-04-25 2020-04-23 Telefield Medical Imaging Limited Method and device for measuring spinal column curvature
CN112734757A (en) * 2021-03-29 2021-04-30 成都成电金盘健康数据技术有限公司 Spine X-ray image cobb angle measuring method
CN113537408A (en) * 2021-09-08 2021-10-22 深圳开立生物医疗科技股份有限公司 Ultrasonic image processing method, device and equipment and storage medium
CN114081471A (en) * 2021-11-11 2022-02-25 宜宾显微智能科技有限公司 Scoliosis cobb angle measurement method based on three-dimensional image and multi-layer sensing
CN114903518A (en) * 2022-04-14 2022-08-16 深圳市第二人民医院(深圳市转化医学研究院) Intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101917918A (en) * 2007-10-30 2010-12-15 埃利普斯科技有限公司 Skeletal manipulation system
US20200121279A1 (en) * 2016-04-25 2020-04-23 Telefield Medical Imaging Limited Method and device for measuring spinal column curvature
CN106725500A (en) * 2017-01-17 2017-05-31 上海脊光医疗科技有限公司 Functional spinal measurement apparatus
CN109223032A (en) * 2017-07-11 2019-01-18 中慧医学成像有限公司 A kind of method of 3-D supersonic imaging detection deformation of spinal column
CN107595387A (en) * 2017-07-28 2018-01-19 浙江大学 A kind of vertebra image generation system and spinal operation navigation positioning system based on ultrasonic rubbing technology
CN112734757A (en) * 2021-03-29 2021-04-30 成都成电金盘健康数据技术有限公司 Spine X-ray image cobb angle measuring method
CN113537408A (en) * 2021-09-08 2021-10-22 深圳开立生物医疗科技股份有限公司 Ultrasonic image processing method, device and equipment and storage medium
CN114081471A (en) * 2021-11-11 2022-02-25 宜宾显微智能科技有限公司 Scoliosis cobb angle measurement method based on three-dimensional image and multi-layer sensing
CN114903518A (en) * 2022-04-14 2022-08-16 深圳市第二人民医院(深圳市转化医学研究院) Intelligent scoliosis Cobb angle measurement method based on three-dimensional ultrasound

Also Published As

Publication number Publication date
CN114903518A (en) 2022-08-16

Similar Documents

Publication Publication Date Title
Kahrs et al. Sonographic prediction of outcome of vacuum deliveries: a multicenter, prospective cohort study
CAMPBELL Early prenatal diagnosis of neural tube defects by ultrasound
Chaoui et al. From nuchal translucency to intracranial translucency: towards the early detection of spina bifida
Ueno et al. A 5-year epidemiological study on the prevalence rate of idiopathic scoliosis in Tokyo: school screening of more than 250,000 children
Malvasi et al. Intrapartum sonography for fetal head asynclitism and transverse position: sonographic signs and comparison of diagnostic performance between transvaginal and digital examination
US20050283070A1 (en) Systems and methods for qualifying symmetry to evaluate medical images
WO2023197924A1 (en) Three-dimensional-ultrasound-based intelligent scoliosis cobb angle measuring method
Seol et al. Standardization of measurement of cervical elastography, its reproducibility, and analysis of baseline clinical factors affecting elastographic parameters
Strouse et al. Non-contrast thin-section helical CT of urinary tract calculi in children
ROBINSON et al. Diagnostic ultrasound: early detection of fetal neural tube defects
Wiafe et al. Intrapartum ultrasound assessment of cervical dilatation and its value in detecting active labor
Bhaduri et al. Fetal anatomic survey using three‐dimensional ultrasound in conjunction with first‐trimester nuchal translucency screening
Drukker et al. Expected‐value bias in routine third‐trimester growth scans
Wee et al. Computerized automatic nasal bone detection based on ultrasound fetal images using cross correlation techniques
Ball et al. Roentgen pelvimetry and fetal cephalometry: a new technic: preliminary report
Hagen et al. Suspicious prenasal skin thickness-to-nasal bone length ratio: prevalence and correlation with other markers in second and third trimester fetuses with Down syndrome
KR20110126388A (en) Display system of 3d ultrasound apparatus and method for displaying thereof
Orth Surface topography and vectors: a new measure for the three dimensional quantification of scoliotic deformity
Desurmont et al. Assessment of fetal head engagement with transperineal ultrasound: searching for the cutoff level
Ferrar et al. Short-term precision for morphometric X-ray absorptiometry
Chen et al. CT measurement and analysis of the target vertebral body in elderly patients with uncompressed osteoporotic thoracolumbar fractures.
Zhong et al. Prenatal Diagnosis of Pierre Robin Sequence and Its Prognosis: A Retrospective Cohort Study
RU2263470C1 (en) Method for predicting dislocation of axis' odontoid process
Ungureanu et al. Open Spina Bifida: The Role of Ultrasound Markers in the First Trimester and Morphopathology Correlation
McAdams et al. The Comparison Between Fetal Kidney and Sacral Length in Determining Gestational Age

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 23787569

Country of ref document: EP

Kind code of ref document: A1