WO2023196787A3 - Improved constructed tissue - Google Patents

Improved constructed tissue Download PDF

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Publication number
WO2023196787A3
WO2023196787A3 PCT/US2023/065291 US2023065291W WO2023196787A3 WO 2023196787 A3 WO2023196787 A3 WO 2023196787A3 US 2023065291 W US2023065291 W US 2023065291W WO 2023196787 A3 WO2023196787 A3 WO 2023196787A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
constructed tissue
improved constructed
improved
recellularizes
Prior art date
Application number
PCT/US2023/065291
Other languages
French (fr)
Other versions
WO2023196787A2 (en
Inventor
Zeeshan Syedain
Richard F. Murphy
Original Assignee
Vascudyne, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vascudyne, Inc. filed Critical Vascudyne, Inc.
Publication of WO2023196787A2 publication Critical patent/WO2023196787A2/en
Publication of WO2023196787A3 publication Critical patent/WO2023196787A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The present invention is a regenerative tissue that, when place in vivo, recellularizes without prior tissue degradation. Process for making the tissue and products made by the tissue are disclosed.
PCT/US2023/065291 2022-04-04 2023-04-03 Improved constructed tissue WO2023196787A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US202263327028P 2022-04-04 2022-04-04
US63/327,028 2022-04-04
US202263332664P 2022-04-19 2022-04-19
US63/332,664 2022-04-19
US202263388025P 2022-07-11 2022-07-11
US63/388,025 2022-07-11

Publications (2)

Publication Number Publication Date
WO2023196787A2 WO2023196787A2 (en) 2023-10-12
WO2023196787A3 true WO2023196787A3 (en) 2023-12-21

Family

ID=88243608

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/065291 WO2023196787A2 (en) 2022-04-04 2023-04-03 Improved constructed tissue

Country Status (1)

Country Link
WO (1) WO2023196787A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120201897A1 (en) * 2009-10-23 2012-08-09 Sewon Cellontech Co., Ltd. Composition for inducing tissue regeneration by activating platelet-rich plasma (prp), and method for manufacturing same
US20180043054A1 (en) * 2016-08-15 2018-02-15 Guangzhou Bioseal Biotech Co. Ltd. Hemostatic compositions and methods of making thereof
US20190224370A1 (en) * 2016-09-06 2019-07-25 President And Fellows Of Harvard College Living devices for replacement of organs or specific organ functions, methods and uses of the same
US20200129667A1 (en) * 2017-06-30 2020-04-30 Vascudyne Inc Regenerative tissue and natural tissue implants
US20210038762A1 (en) * 2018-01-31 2021-02-11 Rokit Healthcare Inc. Bioink composition for cartilage regeneration, method for manufacturing customized scaffold for cartilage regeneration using same, and customized scaffold for cartilage regeneration manufactured using manufacturing method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120201897A1 (en) * 2009-10-23 2012-08-09 Sewon Cellontech Co., Ltd. Composition for inducing tissue regeneration by activating platelet-rich plasma (prp), and method for manufacturing same
US20180043054A1 (en) * 2016-08-15 2018-02-15 Guangzhou Bioseal Biotech Co. Ltd. Hemostatic compositions and methods of making thereof
US20190224370A1 (en) * 2016-09-06 2019-07-25 President And Fellows Of Harvard College Living devices for replacement of organs or specific organ functions, methods and uses of the same
US20200129667A1 (en) * 2017-06-30 2020-04-30 Vascudyne Inc Regenerative tissue and natural tissue implants
US20210038762A1 (en) * 2018-01-31 2021-02-11 Rokit Healthcare Inc. Bioink composition for cartilage regeneration, method for manufacturing customized scaffold for cartilage regeneration using same, and customized scaffold for cartilage regeneration manufactured using manufacturing method

Also Published As

Publication number Publication date
WO2023196787A2 (en) 2023-10-12

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