WO2023155335A1 - 一种可视的自采宫颈细胞取样器 - Google Patents

一种可视的自采宫颈细胞取样器 Download PDF

Info

Publication number
WO2023155335A1
WO2023155335A1 PCT/CN2022/097111 CN2022097111W WO2023155335A1 WO 2023155335 A1 WO2023155335 A1 WO 2023155335A1 CN 2022097111 W CN2022097111 W CN 2022097111W WO 2023155335 A1 WO2023155335 A1 WO 2023155335A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleeve
brush head
brush
coaxially
rod body
Prior art date
Application number
PCT/CN2022/097111
Other languages
English (en)
French (fr)
Inventor
周亮高
Original Assignee
津泰(天津)医疗器械有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 津泰(天津)医疗器械有限公司 filed Critical 津泰(天津)医疗器械有限公司
Publication of WO2023155335A1 publication Critical patent/WO2023155335A1/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661—Endoscope light sources
    • A61B1/0684—Endoscope light sources using light emitting diodes [LED]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/303—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the vagina, i.e. vaginoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0216—Sampling brushes

Definitions

  • the invention belongs to the technical field of medical detection and relates to the technology of a cervical cell sampler, in particular to a visible self-collecting cervical cell sampler.
  • Cervical cell sampling brushes are required for clinical gynecological examinations such as cervical lesion inspection and HPV virus inspection.
  • cervical cell sampling is mostly carried out in clinical departments of medical institutions, and most of the medical devices used are simple cervical cell collectors. Composed of a brush head and a thin handle, the brush head and handle can be rotated synchronously and detachable.
  • the disadvantage of this sampling brush and sampling method is that the vagina needs to be dilated by the dilator first, and the cervix can be completely exposed to the sampler's field of vision before sampling, and the cervical cells cannot be better accessed and transferred after sampling. It can be performed in a medical institution by professional medical personnel.
  • This sampling method requires two kinds of medical devices to be used together, which limits the sampling efficiency, wastes medical consumables, and cannot take care of individual patients with privacy sampling needs. Therefore, it is necessary to develop a cervical cell sampler that can realize user-autonomous sampling and access to cervical cells.
  • the purpose of the present invention is to overcome the deficiencies of the prior art, and provide a visual self-collecting cervical cell sampler, which is easy to operate, can realize self-sampling by users, and realizes accessing cervical cells in combination with the design of the sampling bottle , to achieve sample preservation, thereby improving detection accuracy.
  • a visible self-collecting cervical cell sampler including a cervical brush and a sampling bottle used in conjunction with it
  • the cervical brush includes a brush rod and a sleeve
  • the brush rod includes a rod body
  • the rod body coaxially passes through the sleeve Setting
  • the front end of the rod body is threaded to install the brush head
  • the rear end of the rod body is coaxially installed with the brush handle.
  • the brush handle includes a casing, and an observation mechanism is also arranged in the casing.
  • the housing is provided with a lighting system, a camera system, a circuit system and a power system, and a switch is installed on the housing; the lighting system, the camera system, and the power system are connected by the circuit system and the switch are connected together to realize visual sampling;
  • a ring groove is also formed on the outer wall of the front end of the sleeve;
  • the sampling bottle includes a reagent bottle, a bottle cap and a suction cup base, and the bottle cap is coaxially threaded on the reagent bottle
  • the suction cup base is coaxially installed at the bottom of the reagent bottle; inside the reagent bottle is coaxially formed a protruding ring that matches the ring groove at the front end of the sleeve, and is used for coaxial locking with the sleeve of the cervical brush. position to achieve stable sample storage.
  • the inner middle part of the sleeve is provided with a limiting protrusion;
  • the limiting protrusion is an annular protrusion, and
  • the outer wall of the sleeve is also formed with side wings; the side wings divide the sleeve into the body part and the non-body part.
  • the body part; the body part is the part from the side wings to the front end of the sleeve, and the outer surface of this part is smoothed;
  • the non-body part is the part from the side wings to the rear end of the sleeve, and the outer peripheral wall of this part is Prismatic structure.
  • the rod body is a hollow structure
  • the first half of the rod body is a multi-level adjustment locking part
  • the second half is a through part
  • the multi-level adjustment locking part forms a locking fit with the limit protrusion in the sleeve
  • the front end of the multi-speed adjustment and locking part is also coaxially provided with a brush head connection part
  • the brush head connection part includes a threaded part at the front end and a shaft sleeve part at the rear end, the surface of the shaft sleeve part is smooth, and the shaft sleeve part
  • the threaded part is installed coaxially with the brush head.
  • the multi-gear adjustment locking part includes a plurality of gear positions that are evenly spaced along the axial direction of the rod body, and each gear position is formed by a limiting protrusion that is oppositely arranged.
  • the suction cup base includes a mounting part and a suction cup, and a mounting part is coaxially formed on the upper surface of the suction cup, and the mounting part is a hollow cylindrical structure suitable for the reagent bottle.
  • the bottom of the reagent bottle is made into a conical structure, and a plurality of reinforcing scrapers are evenly spaced along the circumferential direction of the inner wall of the conical structure; an annular mounting part extends axially from the bottom of the reagent bottle , and the conical structure is located inside the annular mounting part.
  • the brush head includes a brush head auxiliary sleeve and a brush head body, the brush head auxiliary sleeve is coaxially connected with the brush head body, and the brush head auxiliary sleeve is a hollow cylindrical structure, which is used to connect with the shaft sleeve of the brush rod body.
  • the front end of the auxiliary cover of the brush head is made into a sawtooth structure.
  • the main body of the brush head includes a connecting ring platform.
  • said connecting ring platform is also made with internal thread, three rings of bristles arranged radially inwardly on the other end of the connecting ring platform, and the bristles from the inner ring to the outer ring The length decreases, and the bristles of each circle contact the cervical wall and open at different angles.
  • a status light is also provided on the housing to observe the status of the mechanism.
  • the power supply system includes a battery and a battery holder, and the battery is installed in the housing through the battery holder to provide power for other systems;
  • the camera system includes an extension tube and a camera, and the extension tube is coaxially installed in the housing The front end of the body, the extension tube is coaxially installed in the rod body and the brush head, and the end of the extension tube is coaxially equipped with a camera; the camera adopts a miniature camera, and the lighting system adopts LED lights, which are arranged around the camera .
  • the circuit system includes a control circuit board, and the control circuit board is provided with an image processing module for image processing and a wireless transmission module connected with the image processing module for wirelessly transmitting images;
  • the wireless transmission module is connected with the mobile terminal.
  • the camera system includes an extension tube and a camera installed at the end of the extension tube, the extension tube is installed on the front end of the housing; a spacer sleeve is placed outside the extension tube, and one end of the spacer sleeve is a closed end. The other end is an open end, and the open end is used for insertion of an extension tube, and the isolation sleeve is transparent at least at the position of the closed end.
  • the rod body includes a multi-level adjustment locking part and a brush head connection part, and the multi-level adjustment locking part is detachably fixedly connected to the brush head connection part; the open end of the spacer sleeve is provided with a radially outwardly extending The eaves are clamped on the shoulders on the connecting part of the brush head.
  • a protruding ring is arranged in the middle of the spacer sleeve, and the end of the brush head connection part abuts on the protruding ring.
  • the rod body includes a multi-level adjustment locking part and a brush head connection part, the multi-level adjustment locking part is detachably fixedly connected to the brush head connection part; the spacer sleeve is integrally formed on the end of the brush head connection part department.
  • the present invention is equipped with an observation mechanism in the cervical brush, which is convenient for users to use independently and greatly improves the sampling efficiency, and due to the design of the matching sampling bottle, the sample can be stored and transferred stably, reducing the contact with the external environment, and improving the quality of life.
  • the accuracy of cell detection, and the cervical brush can be repeatedly sterilized and used, which greatly saves medical consumables.
  • Fig. 1 is a schematic diagram of the explosion structure of the present invention.
  • Fig. 2 is a perspective view of the present invention.
  • Fig. 3 is a schematic diagram of the cervical cell transfer state of the present invention.
  • Fig. 4 is a schematic diagram of the structure of the reagent bottle of the present invention.
  • Fig. 5 is an exploded schematic view of the cervical brush and the reagent bottle of the present invention.
  • Fig. 6 is a schematic diagram of the assembly structure of the rod body and the brush head auxiliary sleeve.
  • Fig. 7 is a schematic diagram of an embodiment of the assembly structure of the rod body and the spacer sleeve.
  • Fig. 8 is a partial cross-sectional view of the assembly structure of the rod body, the brush head auxiliary cover and the spacer cover.
  • FIG. 9 is a partially enlarged view of part A in FIG. 8 .
  • Fig. 10 is a partially enlarged view of part B in Fig. 8 .
  • Fig. 11 is a schematic structural view of an embodiment of a spacer.
  • Fig. 12 is an exploded schematic diagram of an embodiment of the rod body.
  • FIG. 13 is another perspective view of FIG. 12 .
  • Fig. 14 is an exploded schematic view of another embodiment of the present invention.
  • Fig. 15 is a schematic structural diagram of another embodiment of the spacer.
  • a visible self-collecting cervical cell sampler includes a cervical brush 1 and a sampling bottle 2 used in conjunction with it, the cervical brush includes a brush rod and a sleeve 1-3, the brush rod includes a rod body 1-2, the The rod body is set coaxially through the sleeve, the front end of the rod body is threaded to install the brush head 1-4, the rear end is coaxially installed with the brush handle 1-1, and a ring groove 1-3-4 is formed on the outer wall of the front end of the sleeve ;
  • the sampling bottle includes a reagent bottle 2-2, and a protruding ring 2-2-1 matching the ring groove at the front end of the sleeve is coaxially formed in the reagent bottle, and is used to be coaxial with the sleeve of the cervical brush Card position to achieve stable sample storage;
  • the inner middle of the sleeve is provided with a limit protrusion; the limit protrusion is an annular protrusion, and the outer wall of the sleeve is also formed with side wings 1-3-2; specifically, a design at the center of the sleeve A circle of (arc or plane) side wings forms an arc or plane perpendicular to the brush rod on the outer circumference of the sleeve, and the side wings divide the sleeve into the body part 1-3-3 and the non-body part 1- 3-1; the body-entry part is the part from the side wings to the front end of the sleeve, and the outer surface of this part is smoothed, thereby reducing the discomfort of the brush rod penetrating into the vagina, and its length is the body-entry sampling distance; non-entry The body part is the part from the side wings to the rear end of the sleeve.
  • the outer peripheral wall of this part of the sleeve is made of a prism structure, which prevent
  • the function of the above-mentioned flanks is to limit the length of the sleeve deep into the body during sampling, so as to avoid damage caused by the sleeve entering the human body too long due to misoperation, that is, to control the aforementioned sampling distance into the body.
  • the specific distance range follows the following Specifications, the length of the side wings into the body is 4cm to 6cm, and the length of the brush head is 3cm to 4cm.
  • a through hole is coaxially formed in the body of the rod body.
  • the first half of the rod body is a multi-speed adjustment locking part 1-2-1, and the second half is a through part.
  • the through part is a grid hollow structure.
  • the multi-speed adjustment lock The stop part can form a locking fit with the limit protrusion in the sleeve;
  • the brush rod is made of high-quality plastic, and the bar-shaped part is formed by forming a bar-shaped part with both ends integrally formed with the rod body and the middle part suspended, so that the bar-shaped part has elasticity, and then
  • Each bar-shaped part is formed with a structure of a multi-level adjustment locking part;
  • the front end of the multi-level adjustment locking part is also coaxially provided with a brush head connection part, and the brush head connection part includes a threaded part and a shaft sleeve part, and the front end is The threaded part 1-2-3, the rear end is the shaft sleeve part 1-2-2, the surface
  • the multi-gear adjustment locking part includes a plurality of gear positions that are evenly spaced along the axial direction of the rod body, and the multiple gear positions are respectively the first gear position, the second gear position, and the third gear position along the direction from the front end to the rear end.
  • the fourth gear, the fifth gear and the sixth gear; and each gear is composed of oppositely set limit protrusions; the multi-gear adjustment locking part and the limit protrusion form a pull-off buckle , at this time, the brush head can adjust the distance extending out of the sleeve according to the distance required for sampling;
  • the brush head includes a brush head auxiliary cover 1-4-1 and a brush head body 1-4-2.
  • the brush head auxiliary cover is coaxially connected with the brush head body and installed on the rod body.
  • the brush head auxiliary cover is a hollow cylinder Shaped structure, used for coaxial installation with the shaft sleeve of the brush rod body, the front end of the brush head auxiliary sleeve is made into a zigzag structure, one end of the brush head body is designed with a cylindrical connecting ring platform, and one end of the connecting ring platform is also made It has a sawtooth structure, which is used to connect with the sawtooth structure at the front end of the auxiliary sleeve of the brush head, and to limit mutual rotation; and the internal thread matching the screw connection part of the brush head is also made in the connecting ring platform, and the cylindrical Three rings of bristles are arranged radially inwardly on the connecting ring table, and the length of the bristles from the inner ring to the outer ring decreases gradually
  • the brush handle includes a housing, the housing includes a base 1-1-6, a tailstock 1-1-1 and a connecting ring 1-1-4, the base is coaxially fixed on the rear end of the rod body, The rear end of the base is equipped with a tailstock through a connecting ring and a coaxial detachable bolt, and an observation mechanism is arranged in the housing, and the observation mechanism includes a power supply system, a lighting system, a camera system, a circuit system and a switch 1- 1-7; the housing is provided with a lighting system, a camera system, a circuit system, and a power supply system, and a switch is installed on the base of the housing; the lighting system, the camera system, and the The power supply system and the switch are connected together; in addition, a status light 1-1-8 can also be provided on the base of the housing to observe the state of the mechanism, such as whether to turn on the power, whether to open the Wifi connection, the battery Information such as whether the battery is sufficient;
  • the power supply system includes a battery 1-1-2 and a battery holder 1-1-3, the battery is installed in the casing through the battery holder to provide power for the above system, the battery can be a storage battery, and the battery holder There is also a wireless charging receiving module on the top, the wireless charging receiving module is connected to the storage battery, and a charging stand can be equipped on the outside, and a wireless charging transmitting module is arranged on the charging stand. for wireless charging;
  • the camera system includes an extension tube 1-1-9 and a camera head, the extension tube is coaxially installed on the front end of the base of the housing, the extension tube is coaxially penetrated in the through hole of the rod body and the hollow part of the brush head,
  • the end of the extension pipe is coaxially equipped with a camera;
  • the camera adopts a miniature camera, and the periphery of the camera is provided with a lighting system, and the lighting system adopts LED lighting, and specifically 6 LEDs are arranged around the camera Lamp, increasing the illumination intensity of the lighting system through a plurality of LED lights, increasing the clarity of the camera shooting process;
  • the circuit system includes a control circuit board 1-1-5, and the control circuit board is also provided with an image processing module for image processing and a wireless transmission module connected with the image processing module for wirelessly transmitting images module;
  • the wireless transmission module is connected with the mobile terminal, the wireless transmission module is WiFi, bluetooth, etc., and the picture signal collected by the camera is transmitted to the mobile terminal;
  • the mobile terminal can be a mobile phone APP or a computer display screen;
  • the mobile terminal here can be a mobile phone, etc., and the user can use the mobile terminal.
  • the parts during the sampling process are observed on the mobile phone, so as to achieve full collection.
  • the sampling bottle also includes a bottle cap 2-1 and a suction cup base 2-3, and the coaxial thread of the bottle cap is installed at the opening of the reagent bottle for sealing and storing samples;
  • the suction cup base is made of silica gel. It is installed coaxially on the bottom of the reagent bottle, which is convenient for placing the reagent bottle on the operating table stably without fear of the risk of tipping;
  • the suction cup base includes a mounting part and a suction cup, and a mounting part is coaxially formed on the upper surface of the suction cup.
  • the mounting part is a hollow cylindrical structure compatible with the reagent bottle;
  • the bottom of the reagent bottle is made into a conical structure 2-2-3, and a plurality of reinforcing scrapers 2-2-2 are evenly spaced on the inner wall of the conical structure along its circumferential direction
  • the embodiment is provided with four, and each reinforcing scraper protrudes from the inner wall of the bottom of the reagent bottle.
  • the sleeve of the cervical brush of the present invention will completely enter the vagina during sampling.
  • the brush head is pushed out of the sleeve, and the length from the side wings to the top of the brush head is 7cm to 10cm, which is in line with the vaginal length data of ordinary people.
  • the brush head can fully contact the cervix; press the switch button, turn on the camera, and check in real time on the mobile phone whether the brush head is placed near the sampling point through the camera.
  • the present invention is equipped with an observation mechanism in the cervical brush, which is convenient for users to use independently and greatly improves the sampling efficiency, and because of the design of the matching sampling bottle, the sample can be stored and transferred stably, and the cervical brush can be repeatedly sterilized and used. Greatly save medical consumables.
  • a transparent spacer 1-5 is placed outside the extension tube 1-1-9 of the camera system, and one end of the spacer 1-5 is a closed end 1-5. -3, the other end is an open end 1-5-4, the open end 1-5-4 is used for the insertion of the extension tube 1-1-9, as shown in Figures 6 and 7, the spacer 1-5 is located inside the brush head.
  • the isolation sleeve 1-5 can also be transparent at least at the position of the closed end 1-5-3 for image collection by the camera system.
  • the multi-level adjustment locking part 1-2-1 is detachably fixedly connected to the brush head connecting part.
  • the multi-level adjustment locking part 1-2- The end of 1 is provided with a block 1-2-4, and the end of the sleeve part 1-2-2 is provided with a card slot 1-2-5 matched with the block 1-2-4.
  • the gear adjustment locking part 1-2-1 and the shaft sleeve part 1-2-2 can be plugged and connected.
  • the open end 1-5-4 of the spacer 1-5 is provided with an eaves 1-5-2 extending radially outward, as shown in Figure 9, the eaves 1-5-2 5-2 is stuck on the shoulder 1-2-2-1 on the sleeve part 1-2-2, thereby preventing the spacer sleeve 1-5 from protruding outward.
  • a protruding ring part 1-5-1 is provided in the middle of the spacer 1-5, and the end of the threaded part 1-2-3 abuts on the protruding ring part 1 -5-1, so that the isolation sleeve 1-5 is assembled and tightened.
  • the camera system is located in the isolation cover 1-5, and the isolation cover 1-5 isolates the camera system from the external environment.
  • the isolation cover 1-5 can be set as a disposable consumable, and the isolation cover 1-5 can be disassembled and disposed of after use , very easy to clean.
  • the spacer sleeve may also be located at the end of the brush head connecting portion, and form an integral structure with the brush head connecting portion.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

一种可视的自采宫颈细胞取样器，包括宫颈刷（1）以及与其配合使用的取样瓶（2），宫颈刷（1）包括刷杆以及套筒（1-3），刷杆包括杆体（1-2），杆体（1-2）同轴穿过套筒（1-3）设置，杆体（1-2）前端安装刷头（1-4），杆体（1-2）后端安装刷柄（1-1），刷柄（1-1）包括壳体，壳体内还设置有电源系统、照明系统、摄像系统、电路系统和开关（1-1-7）；通过电路系统将照明系统、摄像系统、电源系统及开关（1-1-7）连接在一起，实现可视取样；套筒（1-3）前端的外壁上还制有一环槽（1-3-4）；取样瓶（2）包括试剂瓶（2-2），试剂瓶（2-2）内同轴制有与环槽相适配的凸环（2-2-1），用于与套筒（1-3）同轴卡位，实现稳固存样。本取样器操作简单，实现用户自主采样，使用体验良好；且结合取样瓶（2）的设计实现取存宫颈细胞，实现样本保存，从而提高检测精准度。

Description

一种可视的自采宫颈细胞取样器 技术领域
本发明属于医疗检测技术领域，涉及宫颈细胞取样器技术，尤其是一种可视的自采宫颈细胞取样器。
背景技术
临床上进行宫颈病变检查、HPV病毒检查等妇科检查时需要用到宫颈细胞采样刷，目前宫颈细胞采样大多是在医疗机构的临床科室进行，采用的医疗器械多数是简易的宫颈细胞采集器，其由刷头和细杆刷柄组成，刷头和刷杆可以同步转动、可拆卸。这种采样刷和采样方式的弊端在于，需要由扩阴器先对阴道扩张、将宫颈完全暴露在采样者视野中时才能进行采样，且宫颈细胞采样后不能更好的存取转移，操作只能在医疗机构由专业医务人员进行。这种采样方法需要两种医疗器械配合使用，限制了采样效率、浪费了医用耗材，且无法照顾有隐私采样需求的个人患者。因此，需要开发一种可以实现用户自主采样、存取宫颈细胞的宫颈细胞取样器。
通过检索未发现与本申请相关的专利文献。
发明内容
本发明的目的在于克服现有技术的不足之处，提供一种可视的自采宫颈细胞取样器，该取样器操作简单，可以实现用户自主采样，且结合取样瓶的设计实现存取宫颈细胞，实现样本保存，从而提高检测精准度。
本发明解决其技术问题是采取以下技术方案实现的：
一种可视的自采宫颈细胞取样器，包括宫颈刷以及与其配合使用的取样瓶，所述宫颈刷包括刷杆以及套筒，所述刷杆包括杆体，所述杆体同轴穿过套筒设置，杆体前端螺纹安装刷头，杆体后端同轴安装刷柄，所述刷柄包括壳体，壳体内还设置有观察机构，所述观察机构包括电源系统、照明系统、摄像系统、电路系统和开关；所述壳体内设置有照明系统、摄像系统、电路系统以及电源系统，所述壳体上安装有开关；通过所述电路系统将所述照明系统、所述摄像系统、所述电源系统及开关连接在一起，实现可视取样；所述套筒前端的外壁上还制有一环槽；所述取样瓶包括试剂瓶、瓶盖以及吸盘底座，所述瓶盖同轴螺纹安装在试剂瓶的开口处，所述吸盘底座同轴安装在试剂瓶的底端；试剂瓶内同轴制有一与套筒前端的环槽相适配的凸环，用于与宫颈刷的套筒同轴卡位，实现稳固存样。
而且，所述套筒内中部设置有限位凸起部；该限位凸起部为环形凸起，所述套筒的外壁 还形成有侧翼；所述侧翼将套筒分为入体部分和非入体部分；所述入体部分为侧翼至套筒前端的部分，且该部分的外表面做光滑处理；非入体部分则为侧翼至套筒后端的部分，该部分的套筒外周壁为棱柱结构。
而且，所述杆体为中空结构，杆体前半段为多档调节锁止部，后半段为贯通部，所述多档调节锁止部与套筒内的限位凸起部形成锁止配合；所述多档调节锁止部前端还同轴设置有刷头连接部，所述刷头连接部包括前端的螺纹部和后端的轴套部，所述轴套部表面光滑，所述轴套部配合螺纹部与刷头同轴安装。
而且，所述多档调节锁止部包括沿杆体轴向方向均布间隔设置的多个档位，且每个档位均由相对设置的限位凸点构成。
而且，所述吸盘底座包括安装部以及吸盘，所述吸盘上表面同轴制有一安装部，该安装部为与试剂瓶相适配的中空圆柱体结构。
而且，所述试剂瓶底部制成圆锥结构，且在该圆锥结构内壁上沿着其圆周方向均布间隔设有多根加强刮板；所述试剂瓶的瓶体下方轴向延伸出环形安装部，且圆锥结构位于环形安装部内侧。
而且，所述刷头包括刷头辅助套以及刷头本体，刷头辅助套与刷头本体同轴对接设置，所述刷头辅助套为中空圆柱形结构，用于与刷杆杆体的轴套部同轴安装，所述刷头辅助套前端制成锯齿状结构，所述刷头本体包括连接环台，所述连接环台一端制成锯齿状结构，用于与刷头辅助套前端的锯齿状结构对接，且相互旋转限位；所述连接环台内还制有内螺纹，所述连接环台另一端台面上径向向内间隔设置的三圈刷毛，且内圈至外圈的刷毛长度递减，每圈刷毛接触宫颈壁张开角度不同。
而且，所述壳体上还设有状态灯以观察机构所处于的状态。
而且，所述电源系统包括电池以及电池固定座，所述电池通过电池固定座安装在壳体内，为其他系统进行供电；所述摄像系统包括延伸管以及摄像头，所述延伸管同轴安装在壳体的前端，所述延伸管同轴穿设在杆体以及刷头内，所述延伸管端部同轴安装有摄像头；所述摄像头采用微型摄像头，所述照明系统采用LED灯，设置在摄像头周边。
而且，所述电路系统包括控制电路板，所述控制电路板上设置有用于图像处理的图像处理模块以及与所述图像处理模块相连接、用于将图像进行无线传输的无线传输模块；所述无线传输模块与移动终端相连接。
所述摄像系统包括延伸管以及设置于延伸管端部的摄像头，所述延伸管安装在壳体的前端；在所述延伸管的外侧套有一隔离套，所述隔离套的一端为封闭端，另一端为开放端，所述开放端用于延伸管插入，所述隔离套至少在封闭端的位置透明。
所述杆体包括多档调节锁止部以及刷头连接部，所述多档调节锁止部与刷头连接部可分 离地固定连接；所述隔离套的开放端设置有向径向外侧延伸的檐部，所述檐部卡在所述刷头连接部上的台肩上。
在所述隔离套的中部设置有凸环部，所述刷头连接部的端部顶在所述凸环部上。
所述杆体包括多档调节锁止部以及刷头连接部，所述多档调节锁止部与刷头连接部可分离地固定连接；所述隔离套一体成型于所述刷头连接部的端部。
本发明的优点和积极效果是：
本发明在宫颈刷内设置有观察机构，可以方便用户自主采用同时还大大提高了采样效率，且由于设计与其相匹配的取样瓶，使得样品可以稳固保存转移，减少与外界环境的接触，提高了细胞检测的精准度，而宫颈刷又可以重复消毒利用，大大节省了医用耗材。
附图说明
图1为本发明爆炸结构示意图。
图2为本发明立体图。
图3为本发明宫颈细胞转存状态示意图。
图4为本发明试剂瓶结构示意图。
图5为本发明宫颈刷与试剂瓶的分解示意图。
图6为杆体与刷头辅助套的装配结构示意图。
图7为杆体与隔离套的装配结构一种实施方式示意图。
图8为杆体与刷头辅助套和隔离套装配结构的局部剖视图。
图9为图8中的A部局部放大图。
图10为图8中的B部局部放大图。
图11为隔离套的一种实施方式的结构示意图。
图12为杆体的一种实施方式的分解示意图。
图13为图12的另一角度示意图。
图14为本发明的另一种实施方式的分解示意图。
图15为隔离套的另一种实施方式的结构示意图。
具体实施方式
下面结合附图并通过具体实施例对本发明作进一步详述，以下实施例只是描述性的，不是限定性的，不能以此限定本发明的保护范围。
一种可视的自采宫颈细胞取样器，包括宫颈刷1以及与其配合使用的取样瓶2，所述宫颈刷包括刷杆以及套筒1-3，所述刷杆包括杆体1-2，所述杆体同轴穿过套筒设置，杆体前端螺纹安装刷头1-4，后端同轴安装有刷柄1-1，所述套筒前端的外壁上还制有一环槽1-3-4；所述取样瓶包括试剂瓶2-2，所述试剂瓶内同轴制有一与套筒前端的环槽相适配的凸环2-2-1，用于与宫颈刷的套筒同轴卡位，实现稳固存样；
所述套筒内中部设置有限位凸起部；该限位凸起部为环形凸起，所述套筒的外壁还形成有侧翼1-3-2；具体而言，在套筒中央位置设计了一圈(弧面或平面)侧翼，在套筒外周形成一个与刷杆垂直的弧面或平面，所述侧翼将套筒分为入体部分1-3-3和非入体部分1-3-1；其中入体部分为侧翼至套筒前端的部分，且该部分的外表面做光滑处理，由此减小刷杆穿入阴道的不适感，其长度为入体采样距离；非入体部分则为侧翼至套筒后端的部分，该部分的套筒外周壁制成棱柱结构，止转易握取，不放过任何体验细节感受；本实施例采用材质选用符合医用使用要求的优质塑料，具体可参考已有同类产品；
上述侧翼的作用是采样时，对套筒深入体内的长度起到限位作用，避免因操作失误套筒进入人体过长而引发伤害，即控制前述的入体采样距离，具体距离范围遵循下述规范，侧翼入体部分的长度为4cm至6cm，刷头长度3cm至4cm，采样时入体部分的套筒会完全进入阴道内，此时将采样刷头推出套筒，侧翼到达刷头顶端的长度为7cm至10cm，这符合普通人的阴道长度数据，可以使刷头充分接触宫颈部位；
所述杆体内同轴制有通孔，杆体前半段为多档调节锁止部1-2-1，后半段为贯通部，所述贯通部为格栅镂空结构，所述多档调节锁止部可与套筒内的限位凸起部形成锁止配合；刷杆材质为优质塑料，通过形成两端与杆体一体成型、中部悬空的条形部，使条形部具有弹性，进而在各条形部上形成多档调节锁止部的结构；所述多档调节锁止部前端还同轴设置有刷头连接部，所述刷头连接部包括螺纹部和轴套部，前端为螺纹部1-2-3，后端为轴套部1-2-2，所述轴套部表面光滑，所述轴套部配合螺纹部与刷头同轴连接；
所述多档调节锁止部包括沿杆体轴向方向均布间隔设置的多个档位，多个档位沿前端指向后端方向分别为第一档位、第二档位、第三档位、第四档位、第五档位以及第六档位；且每个档位均由相对设置的限位凸点构成；多档调节锁止部与限位凸起部形成可拉脱扣合，此时，刷头可以根据取样所需距离进行调节伸出套筒的距离；
所述刷头包括刷头辅助套1-4-1以及刷头本体1-4-2，刷头辅助套与刷头本体同轴对接设置安装在杆体上，所述刷头辅助套为中空圆柱形结构，用于与刷杆杆体的轴套部同轴安装，所述刷头辅助套前端制成锯齿状结构，所述刷头本体一端设计圆柱形连接环台，该连接环台一端也制成锯齿状结构，用于与刷头辅助套前端的锯齿状结构对接设，且相互旋转限位；且连接环台内还制与刷头螺纹连接部相适配的内螺纹，所述圆柱形连接环台台面径向向内间隔设置的三圈刷毛，且内圈至外圈的刷毛长度递减，每圈刷毛接触宫颈壁张开角度不同，更易接触到宫颈口；
所述刷柄包括壳体，所述壳体包括基座1-1-6、尾座1-1-1以及连接环1-1-4，所述基座同轴固装在杆体后端，所述基座后端通过连接环还同轴可拆卸螺栓安装有尾座，所述壳体内 还设置有观察机构，所述观察机构包括电源系统、照明系统、摄像系统、电路系统和开关1-1-7；所述壳体内设置有照明系统、摄像系统、电路系统以及电源系统，所述壳体的基座上安装有开关；通过所述电路系统将所述照明系统、所述摄像系统、所述电源系统及开关连接在一起；此外，在所述壳体的基座上还可以设有状态灯1-1-8以观察机构所处于的状态，如是否开机，是否打开Wifi连接，电池电量是否充足等信息；
所述电源系统包括电池1-1-2以及电池固定座1-1-3，所述电池通过电池固定座安装在壳体内，为上述系统进行供电，所述电池可以为蓄电池，且电池固定座上还设置有无线充电接收模块，所述无线充电接收模块与蓄电池相连，外部可以配备充电座，充电座上设置有无线充电发射模块，当宫颈刷放置在充电座时，通过充电座对宫颈刷进行无线充电；
所述摄像系统包括延伸管1-1-9以及摄像头，所述延伸管同轴安装在壳体的基座前端，所述延伸管同轴穿设在杆体的通孔内以及刷头中空部，所述延伸管端部同轴安装有摄像头；所述摄像头采用微型摄像头，所述摄像头周边设置有照明系统，所述照明系统采用LED照明，具体的围绕着所述摄像头的周围设置了6个LED灯，通过多个LED灯增加照明系统的照明强度，增加所述摄像头拍摄过程的清晰度；
所述电路系统包括控制电路板1-1-5，所述控制电路板上还设置有用于图像处理的图像处理模块以及与所述图像处理模块相连接、用于将图像进行无线传输的无线传输模块；所述无线传输模块与移动终端相连接，所述无线传输模块为WiFi、蓝牙等，将摄像头采集到的图片信号传输至移动终端；所述移动终端可以为手机APP或者电脑显示屏等；
具体的，通过摄像头、图像处理模块、无线传输模块等配合作用，将取样时拍摄到的图相经处理后传输至移动终端上，这里的移动终端可以为手机等，使用者可以通过移动终端对取样过程中的部位在手机上观察，从而实现充分采集。
此外，所述取样瓶还包括瓶盖2-1以及吸盘底座2-3，所述瓶盖同轴螺纹安装在试剂瓶的开口处，用于密封存取样品；所述吸盘底座为硅胶材质制成，同轴安装在试剂瓶的底端，便于将试剂瓶稳定放置在操作台上，不惧倾倒风险；所述吸盘底座包括安装部以及吸盘，所述吸盘上表面同轴制有一安装部，该安装部为与试剂瓶相适配的中空圆柱体结构；
在本发明的具体实施中，所述试剂瓶底部制成圆锥结构2-2-3，且在该圆锥结构内壁上沿着其圆周方向均布间隔设有多根加强刮板2-2-2；实施例设置四根，且每根加强刮板均凸出试剂瓶底部内壁，在存样时，刷头的毛刷转动，加强刮板可以刮取毛刷上的宫颈细胞；且为了试剂瓶与吸盘底座更好的安装，所述试剂瓶的瓶体下方轴向延伸出环形安装部2-2-4，且圆锥结构位于环形安装部内侧；
本发明的宫颈刷在采样时入体部分的套筒会完全进入阴道内，此时将刷头推出套筒，侧 翼到达刷头顶端的长度为7cm至10cm，这符合普通人的阴道长度数据，可以使刷头充分接触宫颈部位；按动开关按钮，打开摄像头，通过摄像头在手机上实时查看是否将刷头放置在取样点附近，当刷头设置在取样点附近时，旋转刷柄，旋转取样完毕后，拉动刷杆使刷毛部分完全缩回套筒；抽回套筒取出宫颈刷，将取样瓶吸附在操作台上，打开取样瓶的瓶盖，在试剂瓶内加入保存液，将宫颈刷整体与试剂瓶稳定连接，套筒旋拧到配套保存液中，推动刷杆使刷毛完全浸入保存液中，旋转7-10周，使刷头细胞脱离落入保存液中，然后退回刷头，拔离宫颈刷整体，过程中无需取下刷头，避免因溶入细胞前取下刷头不慎造成不必要污染或震落已经刷取的宫颈脱落细胞，该过程大大降低了宫颈细胞与外界环境的接触，从而提高了检测的精准度。
本发明在宫颈刷内设置有观察机构，可以方便用户自主采用同时还大大提高了采样效率，且由于设计与其相匹配的取样瓶，使得样品可以稳固保存转移，而宫颈刷又可以重复消毒利用，大大节省了医用耗材。
由于在采样过程中，摄像系统会与患者组织接触，因此需要在使用完毕后进行清洗，一方面清洗作业非常不便，另一方面一旦摄像系统上存留有污染物，则会造成患者感染。因此，作为进一步改进，如图8所示，在摄像系统的延伸管1-1-9的外侧套有一透明的隔离套1-5，所述隔离套1-5的一端为封闭端1-5-3，另一端为开放端1-5-4，所述开放端1-5-4用于延伸管1-1-9插入，如图6、7所示，所述隔离套1-5位于刷头内侧。当然，所述隔离套1-5除了由透明材质一体成型之外，也可以至少在封闭端1-5-3的位置透明，用于摄像系统采集影像。
所述多档调节锁止部1-2-1与刷头连接部可分离地固定连接，在本实施例中，如图12、13所示，所述多档调节锁止部1-2-1的端部设置有卡块1-2-4，在轴套部1-2-2的端部设置有与所述卡块1-2-4相配合的卡槽1-2-5，多档调节锁止部1-2-1与轴套部1-2-2能够进行插拔连接。如图11所示，在所述隔离套1-5的开放端1-5-4设置有向径向外侧延伸的檐部1-5-2，如图9所示，所述檐部1-5-2卡在所述轴套部1-2-2上的台肩1-2-2-1上，从而防止隔离套1-5向外脱出。进一步地，如图10所示，在所述隔离套1-5的中部设置有凸环部1-5-1，所述螺纹部1-2-3的端部顶在所述凸环部1-5-1上，从而将隔离套1-5装配紧固。摄像系统位于隔离套1-5内，隔离套1-5将摄像系统与外接环境进行隔离，可以将隔离套1-5设置为一次性耗材，在使用完毕后可以将隔离套1-5拆卸处置，非常方便清洁。
作为本发明的另一种实施方式，如图14、15所示，所述隔离套也可以位于所述刷头连接部的端部，并与所述刷头连接部形成一体结构。
尽管为说明目的公开了本发明的实施例和附图，但是本领域的技术人员可以理解：在不脱离本发明及所附权利要求的精神和范围内，各种替换、变化和修改都是可能的，因此，本发明的范围不局限于实施例和附图所公开的内容。

Claims (14)

  1. 一种可视的自采宫颈细胞取样器，其特征在于：包括宫颈刷以及与其配合使用的取样瓶，所述宫颈刷包括刷杆以及套筒，所述刷杆包括杆体，所述杆体同轴穿过套筒设置，杆体前端螺纹安装刷头，杆体后端同轴安装刷柄，所述刷柄包括壳体，壳体内还设置有观察机构，所述观察机构包括电源系统、照明系统、摄像系统、电路系统和开关；所述壳体内设置有照明系统、摄像系统、电路系统以及电源系统，所述壳体上安装有开关；通过所述电路系统将所述照明系统、所述摄像系统、所述电源系统及开关连接在一起，实现可视取样；所述套筒前端的外壁上还制有一环槽；所述取样瓶包括试剂瓶、瓶盖以及吸盘底座，所述瓶盖同轴螺纹安装在试剂瓶的开口处，所述吸盘底座同轴安装在试剂瓶的底端；试剂瓶内同轴制有一与套筒前端的环槽相适配的凸环，用于与宫颈刷的套筒同轴卡位，实现稳固存样。
  2. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述套筒内中部设置有限位凸起部；该限位凸起部为环形凸起，所述套筒的外壁还形成有侧翼；所述侧翼将套筒分为入体部分和非入体部分；所述入体部分为侧翼至套筒前端的部分，且该部分的外表面做光滑处理；非入体部分则为侧翼至套筒后端的部分，该部分的套筒外周壁为棱柱结构。
  3. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述杆体为中空结构，杆体前半段为多档调节锁止部，后半段为贯通部，所述多档调节锁止部与套筒内的限位凸起部形成锁止配合；所述多档调节锁止部前端还同轴设置有刷头连接部，所述刷头连接部包括前端的螺纹部和后端的轴套部，所述轴套部表面光滑，所述轴套部配合螺纹部与刷头同轴安装。
  4. 根据权利要求3所述的可视的自采宫颈细胞取样器，其特征在于：所述多档调节锁止部包括沿杆体轴向方向均布间隔设置的多个档位，且每个档位均由相对设置的限位凸点构成。
  5. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述吸盘底座包括安装部以及吸盘，所述吸盘上表面同轴制有一安装部，该安装部为与试剂瓶相适配的中空圆柱体结构。
  6. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述试剂瓶底部制成圆锥结构，且在该圆锥结构内壁上沿着其圆周方向均布间隔设有多根加强刮板；所述试剂瓶的瓶体下方轴向延伸出环形安装部，且圆锥结构位于环形安装部内侧。
  7. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述刷头包括刷头辅助套以及刷头本体，刷头辅助套与刷头本体同轴对接设置，所述刷头辅助套为中空圆柱形结构，用于与刷杆杆体的轴套部同轴安装，所述刷头辅助套前端制成锯齿状结构，所述刷头本体包括连接环台，所述连接环台一端制成锯齿状结构，用于与刷头辅助套前端的锯齿状结 构对接，且相互旋转限位；所述连接环台内还制有内螺纹，所述连接环台另一端台面上径向向内间隔设置的三圈刷毛，且内圈至外圈的刷毛长度递减，每圈刷毛接触宫颈壁张开角度不同。
  8. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述壳体上还设有状态灯以观察机构所处于的状态。
  9. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述电源系统包括电池以及电池固定座，所述电池通过电池固定座安装在壳体内，为其他系统进行供电；所述摄像系统包括延伸管以及摄像头，所述延伸管同轴安装在壳体的前端，所述延伸管同轴穿设在杆体以及刷头内，所述延伸管端部同轴安装有摄像头；所述摄像头采用微型摄像头，所述照明系统采用LED灯，设置在摄像头周边。
  10. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述电路系统包括控制电路板，所述控制电路板上设置有用于图像处理的图像处理模块以及与所述图像处理模块相连接、用于将图像进行无线传输的无线传输模块；所述无线传输模块与移动终端相连接。
  11. 根据权利要求1所述的可视的自采宫颈细胞取样器，其特征在于：所述摄像系统包括延伸管以及设置于延伸管端部的摄像头，所述延伸管安装在壳体的前端；在所述延伸管的外侧套有一隔离套，所述隔离套的一端为封闭端，另一端为开放端，所述开放端用于延伸管插入，所述隔离套至少在封闭端的位置透明。
  12. 根据权利要求11所述的可视的自采宫颈细胞取样器，其特征在于：所述杆体包括多档调节锁止部以及刷头连接部，所述多档调节锁止部与刷头连接部可分离地固定连接；所述隔离套的开放端设置有向径向外侧延伸的檐部，所述檐部卡在所述刷头连接部上的台肩上。
  13. 根据权利要求12所述的可视的自采宫颈细胞取样器，其特征在于：在所述隔离套的中部设置有凸环部，所述刷头连接部的端部顶在所述凸环部上。
  14. 根据权利要求11所述的可视的自采宫颈细胞取样器，其特征在于：所述杆体包括多档调节锁止部以及刷头连接部，所述多档调节锁止部与刷头连接部可分离地固定连接；所述隔离套一体成型于所述刷头连接部的端部。
PCT/CN2022/097111 2022-02-16 2022-06-06 一种可视的自采宫颈细胞取样器 WO2023155335A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202210143187.5 2022-02-16
CN202210143187.5A CN114403942A (zh) 2022-02-16 2022-02-16 一种可视的自采宫颈细胞取样器

Publications (1)

Publication Number Publication Date
WO2023155335A1 true WO2023155335A1 (zh) 2023-08-24

Family

ID=81261006

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2022/097111 WO2023155335A1 (zh) 2022-02-16 2022-06-06 一种可视的自采宫颈细胞取样器

Country Status (2)

Country Link
CN (1) CN114403942A (zh)
WO (1) WO2023155335A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117368122A (zh) * 2023-12-07 2024-01-09 津泰(天津)医疗器械有限公司 一种基于比色卡的frd宫颈染色实时比对方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114403942A (zh) * 2022-02-16 2022-04-29 津泰(天津)医疗器械有限公司 一种可视的自采宫颈细胞取样器
CN218979004U (zh) * 2022-10-24 2023-05-09 津泰(天津)医疗器械有限公司 宫颈细胞取样器刷头以及宫颈细胞取样器
CN115990040A (zh) * 2022-11-23 2023-04-21 弗雷米德生物医药技术（天津）有限公司 一种e7蛋白自行居家检测用宫颈刷及其检查方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070073186A1 (en) * 2005-09-27 2007-03-29 Decker A Combination Self Adjusting Endocervical / Exocervical Sampling Device and Cell Transport / Preservation System
CN104771193A (zh) * 2015-04-08 2015-07-15 黄健 组合式阴道宫颈检测装置及可视化宫颈细胞取样器
CN105395222A (zh) * 2014-09-16 2016-03-16 北京大学深圳医院 宫颈阴道脱落细胞自采收装置
CN107811657A (zh) * 2017-11-23 2018-03-20 北京海普威生物技术有限公司 一种子宫颈细胞采样刷
CN210972169U (zh) * 2019-11-13 2020-07-10 安徽宸瑞医药包装有限公司 一种无内衬避光防漏试剂瓶
CN213283096U (zh) * 2020-06-30 2021-05-28 武汉市中心医院 一种家庭自用宫颈筛查细胞取样刷
CN215349123U (zh) * 2021-01-16 2021-12-31 上海市第六人民医院金山分院(上海市金山区中心医院、上海市金山区中医医院) 一种可调节宫颈标本刷
CN114403942A (zh) * 2022-02-16 2022-04-29 津泰(天津)医疗器械有限公司 一种可视的自采宫颈细胞取样器

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070073186A1 (en) * 2005-09-27 2007-03-29 Decker A Combination Self Adjusting Endocervical / Exocervical Sampling Device and Cell Transport / Preservation System
CN105395222A (zh) * 2014-09-16 2016-03-16 北京大学深圳医院 宫颈阴道脱落细胞自采收装置
CN104771193A (zh) * 2015-04-08 2015-07-15 黄健 组合式阴道宫颈检测装置及可视化宫颈细胞取样器
CN107811657A (zh) * 2017-11-23 2018-03-20 北京海普威生物技术有限公司 一种子宫颈细胞采样刷
CN210972169U (zh) * 2019-11-13 2020-07-10 安徽宸瑞医药包装有限公司 一种无内衬避光防漏试剂瓶
CN213283096U (zh) * 2020-06-30 2021-05-28 武汉市中心医院 一种家庭自用宫颈筛查细胞取样刷
CN215349123U (zh) * 2021-01-16 2021-12-31 上海市第六人民医院金山分院(上海市金山区中心医院、上海市金山区中医医院) 一种可调节宫颈标本刷
CN114403942A (zh) * 2022-02-16 2022-04-29 津泰(天津)医疗器械有限公司 一种可视的自采宫颈细胞取样器

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117368122A (zh) * 2023-12-07 2024-01-09 津泰(天津)医疗器械有限公司 一种基于比色卡的frd宫颈染色实时比对方法
CN117368122B (zh) * 2023-12-07 2024-02-13 津泰(天津)医疗器械有限公司 一种基于比色卡的frd宫颈染色实时比对方法

Also Published As

Publication number Publication date
CN114403942A (zh) 2022-04-29

Similar Documents

Publication Publication Date Title
WO2023155335A1 (zh) 一种可视的自采宫颈细胞取样器
CN203693555U (zh) 阴道宫颈自检仪
WO2023155486A1 (zh) 可调节长度的自采宫颈细胞取样器及取样、存样方法
CN103565394A (zh) 无线自检口腔镜
CN108567400A (zh) 一种便于儿科检查用的多功能压舌板
CN207679421U (zh) 一种耳鼻喉观察镜
CN112754411A (zh) 一种自清洁式无线可视喉镜
CN200991221Y (zh) 一种医用电子检测仪
CN203749379U (zh) 带臭氧消毒的自检口腔镜
CN218128599U (zh) 一种可视的自采宫颈细胞取样器
CN212037457U (zh) 一种口腔粘膜检测器
CN210433499U (zh) 一种唾液收集装置
CN212037482U (zh) 新型皮肤性病检查器装置
CN204655000U (zh) 组合式阴道宫颈检测装置及可视化宫颈细胞取样器
CN112603238A (zh) 一种便携式无线可视喉镜
CN207785187U (zh) 一种智能宫颈细胞取样装置
CN202654104U (zh) 一种儿童眼病红外筛查装置
CN206603755U (zh) 一种多功能口腔镜
CN215178725U (zh) 粪便标本取样装置
CN103519774A (zh) 一种同步口腔镜
CN106236005B (zh) 检测治疗棒及检测治疗装置
CN203354525U (zh) 手持式舌象采集装置
CN203354526U (zh) 小型化手持式舌象采集装置
CN213606240U (zh) 一种便于随身携带的wifi可视耳镜
CN104083181B (zh) 阴道分泌物自主取材检测诊断设备

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22926645

Country of ref document: EP

Kind code of ref document: A1