WO2023122787A1 - Transducteur de pression pour injections - Google Patents

Transducteur de pression pour injections Download PDF

Info

Publication number
WO2023122787A1
WO2023122787A1 PCT/US2022/082338 US2022082338W WO2023122787A1 WO 2023122787 A1 WO2023122787 A1 WO 2023122787A1 US 2022082338 W US2022082338 W US 2022082338W WO 2023122787 A1 WO2023122787 A1 WO 2023122787A1
Authority
WO
WIPO (PCT)
Prior art keywords
pressure
injection
pressure transducer
lumen
reservoir
Prior art date
Application number
PCT/US2022/082338
Other languages
English (en)
Inventor
Ray King
Original Assignee
Ray King
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ray King filed Critical Ray King
Publication of WO2023122787A1 publication Critical patent/WO2023122787A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/488—Limiting injection pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula

Definitions

  • This invention relates generally to methods and systems for the safe inj ection of functional and/or cosmetic substance into the vessels of the body, such as to help reduce or obviate the risk of complications (e.g. stroke or blindness) by retrograde injection of the injected substance into another undesired artery, particularly to methods and systems utilizing pressure-mediated flow control in a syringe.
  • a method that relies upon subjective “slow” injection is oblivious to the actual key force to overcome - the worst-case diastolic blood pressure in a given patient.
  • the present invention relates to methods and systems for accurately measuring the injection pressure of a filler into the arterial vessels of the body for functional and/or cosmetic procedures, and maintaining this injection pressure below a desired pressure.
  • the injection pressure may be kept below a specific patient’s diastolic blood pressure, hence reducing or negating the incidence of function-threatening embolism into a subsequent artery due to retrograde substance injection.
  • a pressure transducer may be desirable to intrinsically control the injection pressure in response to the applied pressure on the syringe (e.g. via a plunger or other actuator).
  • a device e.g. specifically tailored with properties to a specific material being injected which consistently limits the injection pressure to being lower than an intended value is desirable, such as through intrinsic response by a pressure transducer.
  • a pressure transducer may be placed to be in contact or fluid communication with both the reservoir and the lumen of a needle attached to a syringe such that pressure changes in the reservoir cause the pressure transducer to alter the flow characteristics of a fluid entering the lumen of the needle from the reservoir.
  • the pressure transducer may include a flexible membrane which is adapted to deform due to pressure in the reservoir and constrict or otherwise change the size of an entry into the lumen of the needle attached to a syringe.
  • the flexible membrane may generally constrict or otherwise reduce the size of the entry into the lumen of the needle attached to a syringe in response to an increased or high amount of pressure in the reservoir to, for example, restrict the flow through the lumen. This may be desirable to reduce the effective pressure of the fluid exiting the needle due to the decreased flow.
  • a flexible membrane may form a concentric channel that connects to the lumen entrance and may collapse inward to shrink the size of the channel in response to increased pressure in the reservoir. In response to a decreased or lower level of pressure in the reservoir, the flexible membrane may then flex back or relax to increase or return the channel size to enable higher flow into the lumen through the larger channel.
  • the reservoir, pressure transducer and entrance to the lumen of a needle in a syringe may be configured such that pressure applied to a fluid in the reservoir causes the fluid to flow past or otherwise contact to exert pressure on the pressure transducer prior to entering the entrance to the lumen.
  • a channel or other flow guide (or multiple) may be provided to direct flow of a fluid in the reservoir being pressurized, such as by a plunger or other actuator, such that the entrance of the lumen is placed downstream from the pressure transducer and the plunger or other actuator does not directly pressurize the fluid at the entrance of the lumen without first passing by or contacting the pressure transducer. This may be useful in aiding the pressure transducer in acting on the entrance to the lumen due to fluid pressure prior to the fluid being able to enter the lumen for upstream intrinsic control of the flow into the lumen.
  • FIG. 1 illustrates a schematic view of a syringe and needle with a pressure transducer with lower pressure being applied and a flexible membrane unconstructed to enable flow into the needle;
  • FIG. 2 illustrates a schematic view of a syringe and needle with a pressure transducer with higher pressure being applied and a flexible membrane being constricted to decrease flow into the needle
  • the present invention relates to methods and systems for accurately measuring the injection pressure of a filler into the arterial vessels of the body for functional and/or cosmetic procedures, and maintaining this injection pressure below a desired pressure.
  • the injection pressure may be kept below a specific patient’s diastolic blood pressure, hence reducing or negating the incidence of function-threatening embolism into a subsequent artery due to retrograde substance injection.
  • a pressure transducer may be desirable to intrinsically control the injection pressure in response to the applied pressure on the syringe (e.g. via a plunger or other actuator).
  • a device e.g.
  • a flexible membrane may form a concentric channel that connects to the lumen entrance 112 and may collapse inward to shrink the size of the channel in response to increased pressure in the reservoir
  • the concentric channel may form a part of the channel in the entry 112, such as illustrated with the pressure transducer 106 placed in the middle portion of the entry 112 with section 112a extending from it.
  • the flexible membrane may then flex back or relax to increase the channel size to enable higher flow into the lumen 111 through the larger channel.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne des procédés et des systèmes pour mesurer avec précision la pression d'injection d'une charge dans les vaisseaux artériels du corps pour des procédures fonctionnelles et/ou cosmétiques, et maintenir cette pression d'injection sous une pression souhaitée. Par exemple, la pression d'injection peut être maintenue au-dessous d'une pression sanguine diastolique d'un patient spécifique, ce qui réduit ou annule l'incidence d'une embolie mettant en danger une fonction dans une artère suivante en raison de l'injection de substance rétrograde. Un transducteur de pression peut être souhaitable pour réguler intrinsèquement la pression d'injection en réponse à la pression appliquée sur la seringue (par exemple par l'intermédiaire d'un piston ou d'un autre actionneur). Idéalement, un dispositif (par exemple spécifiquement adapté à des propriétés à un matériau spécifique injecté) qui limite de façon constante la pression d'injection à une valeur inférieure à une valeur prévue est souhaitable, par exemple par l'intermédiaire d'une réponse intrinsèque par un transducteur de pression.
PCT/US2022/082338 2021-12-23 2022-12-23 Transducteur de pression pour injections WO2023122787A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163293238P 2021-12-23 2021-12-23
US63/293,238 2021-12-23

Publications (1)

Publication Number Publication Date
WO2023122787A1 true WO2023122787A1 (fr) 2023-06-29

Family

ID=86903831

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/082338 WO2023122787A1 (fr) 2021-12-23 2022-12-23 Transducteur de pression pour injections

Country Status (1)

Country Link
WO (1) WO2023122787A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4332249A (en) * 1980-08-01 1982-06-01 Sherwood Medical Industries, Inc. Filter and valve assembly for hypodermic syringe
US4403988A (en) * 1980-08-21 1983-09-13 The Kendall Company Syringe assembly
US20030225371A1 (en) * 2002-05-28 2003-12-04 Macosta Medical U. Method and apparatus to decrease the risk of intraneuronal injection during administration of nerve block anesthesia
US20080015406A1 (en) * 2005-02-24 2008-01-17 Dlugos Daniel F External Mechanical Pressure Sensor for Gastric Band Pressure Measurements
US7955301B1 (en) * 2010-01-27 2011-06-07 Warsaw Orthopedic, Inc. Injection shut off valve with pressure actuator for delivery of compositions
US20140066696A1 (en) * 2010-04-28 2014-03-06 Allergan, Inc. Method and system for determining the pressure of a fluid in a syringe, an access port, a catheter, and a gastric band
US20190193921A1 (en) * 2015-09-11 2019-06-27 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4332249A (en) * 1980-08-01 1982-06-01 Sherwood Medical Industries, Inc. Filter and valve assembly for hypodermic syringe
US4403988A (en) * 1980-08-21 1983-09-13 The Kendall Company Syringe assembly
US20030225371A1 (en) * 2002-05-28 2003-12-04 Macosta Medical U. Method and apparatus to decrease the risk of intraneuronal injection during administration of nerve block anesthesia
US20080015406A1 (en) * 2005-02-24 2008-01-17 Dlugos Daniel F External Mechanical Pressure Sensor for Gastric Band Pressure Measurements
US7955301B1 (en) * 2010-01-27 2011-06-07 Warsaw Orthopedic, Inc. Injection shut off valve with pressure actuator for delivery of compositions
US20140066696A1 (en) * 2010-04-28 2014-03-06 Allergan, Inc. Method and system for determining the pressure of a fluid in a syringe, an access port, a catheter, and a gastric band
US20190193921A1 (en) * 2015-09-11 2019-06-27 New Product Development Concepts Llc Telescoping Syringe with One-Way Valve

Similar Documents

Publication Publication Date Title
JP3860835B2 (ja) 特に医療を目的とする圧力を制御して流体を取扱う装置
JP6803929B2 (ja) 向上した補強バルーンカテーテル
US5176698A (en) Vented dilatation cathether and method for venting
US5453097A (en) Control of fluid flow
US6348043B1 (en) Multi-dose infusion pump providing minimal flow between doses
DE3138620A1 (de) Dilatationsvorrichtung
JP2001505087A (ja) ニードルレスインジェクションサイト
US20080097379A1 (en) Ophthalmic injection method
US11826541B2 (en) Sliding syringe cap for separate filling and delivery
US20080125712A1 (en) Ophthalmic injection system
US11931544B2 (en) Bolus delivery device
US20040172008A1 (en) Hemostasis valve and method of using a hemostasis valve
US20220273867A1 (en) Bladder for an infusion assembly
JPS61162956A (ja) リ−クバル−ンカテ−テル
WO2023122787A1 (fr) Transducteur de pression pour injections
CA2436543C (fr) Procede et appareil de remplissage de capsules de seringues sans aiguille
CN108744232A (zh) 用于预防灌注出血的减流装置及系统
US11167089B2 (en) Reduced sputtering syringe
US11351301B2 (en) Mandrel for an infusion assembly
JPH10179749A (ja) インフュージョンカテーテル
US20230330332A1 (en) Pressure transducer for injections
JPH01135970A (ja) 流れ制御装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22912768

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE