WO2023115745A1

WO2023115745A1 - Portable apparatus for precise and rapid icing, compression and administration

Info

Publication number: WO2023115745A1
Application number: PCT/CN2022/084955
Authority: WO
Inventors: 张新涛; 曾晖; 张超; 黄宇; 崔丰曦; 李文强; 胡汉林; 赵以坤; 张航; 周德生; 金彦霖; 黄海龙; 谢明河; 张俊林; 饶绍涛
Original assignee: 北京大学深圳医院; 龙尾电子（深圳）有限公司
Priority date: 2021-12-22
Filing date: 2022-04-02
Publication date: 2023-06-29
Also published as: CN114191168A

Abstract

A portable apparatus for precise and rapid icing, compression and administration, which apparatus relates to the technical field of medical devices, and solves the technical problems in the prior art of a normal icing temperature not being low enough and a normal pressure being relatively low at an application site, an operation being complex, and a treatment effect being relatively poor when the site of an injury of a patient is under the joint action of icing and compression. The apparatus comprises a temperature and pressure conducting module (1), a temperature changing module (2) and a compression module (3), wherein the temperature and pressure conducting module (1) is a solid member, the temperature and pressure conducting module (1) can be attached to a site of injury of a patient and can limit same by means of the compression module (3); the compression module (3) can apply a pressure to the site of injury of the patient by means of the temperature and pressure conducting module (1); and the temperature changing module (2) can transfer generated energy to the site of injury of the patient by means of the temperature and pressure conducting module (1), and the temperature changing module (2) is detachably connected to the temperature and pressure conducting module (1).

Description

Accurate and rapid ice compression pressurized drug delivery portable device

technical field

The invention relates to the technical field of medical equipment, in particular to a portable device for precise and rapid ice compress pressurized administration.

Background technique

In clinical practice, PRICE is the basic method for postoperative and sports sprains (PRICE: P protection, R rest, I ice compress, C pressurization, E elevation), which has analgesic, detumescence, and anti-inflammatory effects. Within hours is the basic physical method; it is currently recognized as a very effective and necessary method for the treatment of acute injury and early postoperative pain and swelling, and is recommended by clinical guidelines.

In clinical practice, the use of ice compresses is mainly applied continuously within 24-48 hours after injury or surgery (every 2 hours, ice compresses for 15 minutes, and ice compresses are stopped for the rest of the time to avoid secondary vasodilation reactions); or after functional training application. Ice application mainly stimulates cold receptors, which immediately causes small blood vessels to constrict through axonal reflex, increases blood viscosity, decreases blood flow velocity, and lowers tissue temperature, which plays a role in hemostasis and further reduces the metabolic activity of cells. Cause damage to other tissues to control swelling; reduce the conduction velocity of sensory nerves, especially pain-conducting thin fibers, increase the pain valve, and block the conduction of pain impulses through the valve control mechanism to relieve pain.

Compression restricts tissue bleeding and swelling, and acts as a compression hemostasis, especially in places with many soft tissues and cysts, such as knee joints, ankle joints, and radial joints. Pressurization reduces the interstitial space, limits the volume of the cyst cavity, and changes the pressure difference between the interstitial fluid and the circulatory system to achieve full-cycle hemostasis.

At present, medical staff usually use ice packs or ice buckets filled with ice cubes to apply ice to the injured part of the patient. However, due to the low comprehensive thermal conductivity of the cold transfer path in this conventional ice application method, there are many air gaps (microscopic) at the contact interface. , the heat transfer efficiency is low, and the actual skin ice temperature is not low enough; in addition, the heat release process of the ice cube is not easy to control, and the temperature difference between the cold source and the skin is uncontrollable; and the ice cube is a cold storage method. The cold cycle is long, the unit of measurement is hours, and it lacks timeliness when outdoors and emergencies;

Conventional bandages, airbags, and sandbags are affected by human body structure and body position, and the operation is cumbersome. The normal pressure on the injured area is relatively small, the effective pressurization efficiency is low, and the experience is poor.

Affected by separate ice compress and pressurization methods, the normal temperature and pressure values of conventional ice compress and pressurization at the same time often cannot reach the ideal value, uncontrollable, poor experience, and often require professional operation, and the treatment effect is relatively Difference. The therapeutic effect is relatively poor when ice compresses and compression methods work together.

Contents of the invention

The purpose of the present invention is to provide a portable device for precise and rapid ice compress and pressurized drug delivery, so as to solve the problem that the normal ice compress temperature of the application site is not low enough and the normal pressure is biased when the ice compress and pressurize the injured position of the patient are combined in the prior art. Low, cumbersome operation, poor treatment effect technical problems. The many technical effects that can be produced by the preferred technical solutions among the many technical solutions provided by the present invention are described in detail below.

To achieve the above object, the present invention provides the following technical solutions:

The present invention provides a portable device for precise and rapid ice compressing pressurized medicine, which includes a temperature conducting and pressure guiding module, a temperature changing module and a pressurizing module, wherein the temperature guiding and pressure guiding module is a solid piece, and the temperature guiding and pressure guiding module is a solid piece. The module can be attached to the injured position of the patient, and the temperature and pressure guiding module can be restricted at the injured position of the patient through the pressurization module. The temperature-changing module can transmit the generated energy to the injured part of the patient through the temperature-guiding and pressure-guiding module, and the temperature-changing module is detachably connected to the temperature-guiding and pressure-guiding module.

Optionally, the shape of the bonding surface on the temperature conducting and pressure guiding module conforms to ergonomics.

Optionally, the temperature and pressure guiding module is integrally formed; or, the temperature and pressure guiding module is a mosaic structure; the thermal conductivity of the temperature and pressure guiding module is greater than 10W/m·k; the temperature and pressure guiding module The normal thickness of the pressure guiding module is less than 1cm; the material used in the temperature guiding and pressure guiding module is JDBM magnesium alloy.

Optionally, the temperature and pressure guiding module includes a bonding plate and a connecting part, the bonding plate is fixedly connected to one end surface of the connecting part, and the other end surface of the connecting part can be detachably connected to the temperature variable module , or the connection part is connected with the pressure module, and the fitting plate can be fitted on the injured position of the patient.

Optionally, a flexible layer is also included, the flexible layer is pasted on the bonding surface of the temperature conduction and pressure conduction module;

The Young's modulus of elasticity of the flexible layer ranges from 10 kPa to 100 kPa, and the thickness of the flexible layer is less than 1 cm.

Optionally, a drug-loaded coating is also included, and the drug-loaded coating is used to fit on human skin.

Optionally, the temperature variable module includes a housing, a semiconductor cooling chip, a first metal sheet, a second metal sheet, a control circuit, a temperature sensor and a data regulator, and the housing can be detachably connected to the temperature guide On the pressure guiding module, the semiconductor cooling sheet, the first metal sheet, the second metal sheet, the control circuit and the temperature sensor are all located in the housing, and the first metal sheet is connected to the semiconductor cooling sheet One end, the second metal sheet is connected to the other end of the semiconducting cooling plate, the data adjuster is electrically connected to the temperature sensor, and the semiconductor cooling plate, the control circuit and the data adjusting unit are electrically connected connected, the control circuit can change the hot and cold ends of the peltier, and the data adjuster can adjust the working temperature of the peltier;

The temperature variable module has a freezing mode, a heating mode and a normal temperature mode. When the temperature variable module is in the freezing mode, the temperature of the human skin is between 4°C and 15°C; when the temperature variable module is in the heating mode, the temperature of the human skin is The temperature is between 39°C and 42°C; when the temperature variable module is in the normal temperature mode, the temperature of the human skin is between 15°C and 39°C.

Optionally, the temperature-changing module is a box with a storage space, and ice cubes or reaction materials can be stored in the box.

Optionally, the pressurization module is a strap assembly or an airbag assembly or a twist assembly or a Velcro assembly;

The number of the pressurization module is at least one;

The normal pressure applied by the pressurizing module to the temperature conducting and pressure conducting module ranges from 0 to 100kpa.

Optionally, it also includes a cover, the cover can cover a part of the pressurization module and can be detachably connected with the temperature change module; or, the cover can cover a part of the pressurization module and can It is detachably connected with the temperature conducting and pressure guiding module.

The present invention provides a portable device for precise and rapid ice compressing and pressurized drug administration. When the product is in use, the pressurizing module, the temperature-changing module and the temperature-conducting and pressure-conducting module can be connected to form a module, and then the module can be pasted Closed to the injured site, by changing the pressure value of the pressurized module, the pressure applied by the temperature-conducting and pressure-conducting module to the injured site can be changed. Because the pressure of solid parts is non-destructive and transmissible, the pressure exerted by the temperature-conducting and pressure-conducting module on the injured site has a clear digital relationship with the pressure value given by the pressurization module, which is convenient for precise control of the pressure value; the ergonomic characteristics of the temperature-conducting and pressure-conducting module , so the pressure is concentrated on the sticking area; the pressurization module is a deformation force, non-gravity, and is not affected by the position of the body. Most daily activity scenes can also continue to pressurize, achieving a skin normal pressure of 0-100kpa. Since the temperature-conducting and pressure-conducting module in the module is a solid part and can be attached to the injured position, that is, the heat conduction coefficient of the path can be determined; the ergonomic characteristics of the temperature-conducting and pressure-conducting module and the pressure of the pressurizing module have improved The proportion of heat conduction paths, and the large area of heat radiation phenomenon (microscopic angle) caused by the large amount of air at the contact interface in the traditional way, that is, the comprehensive thermal conductivity of the path is larger and the thermal resistance is smaller, which can reduce the skin more quickly. Temperature; and the temperature variable module is a controllable electric cooling module, the skin temperature is easy to be accurately controlled at the second level according to the application, and it is easy to control the skin temperature (4-30°C); ergonomics and deformation pressurization, no body position If affected, most daily activities can also be applied with ice at the same time. Since the cooling and pressure guiding paths can share the same path, it also satisfies the time reuse problem of ice application and pressurization, and improves the timeliness. The ergonomic structure of the temperature and pressure guiding module can be operated by non-professionals within 10 seconds. The invention is easier to realize the application temperature gradient requirements and pressure gradient requirements of the epidermis, and solves the problem that the normal ice temperature of the application site is not low enough and the normal pressure is low when the ice compress and pressurization are applied to the injured position of the patient in the prior art. The operation is cumbersome and the treatment effect is relatively poor technical problem.

The preferred technical solution of the present invention can also produce the following technical effects at least:

The present invention adopts the electric-cold-heat temperature-changing method, which can quickly change the temperature (second level). Under normal working conditions, the temperature can meet the normal ice compress and hot compress requirements (skin temperature 4-42°C), and it is easy to control the temperature curve. According to the clinical Research data programming and autonomous control.

The flexible layer is made of materials with an elastic modulus of 10kpa to 100kpa, which can further adapt to ergonomics, independently according to the swelling cycle deformation status and individual differences, and enhance the experience.

The temperature and pressure guiding module can also be a mosaic module, which further improves the performance of ergonomic fit.

The temperature guide and pressure guide module is made of antibacterial metal materials, such as JDBM magnesium alloy material, which reduces the probability of infection and is more suitable for long-term use.

The drug-loaded coating can achieve external drug administration while ice compressing and pressurization time are reused, further improving time reusability.

The temperature and pressure guiding module and the pressurizing module can also be used in combination separately to realize a single pressurizing function, and the pressurizing range is 0 to 100kpa.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

Fig. 1 is a schematic diagram of the structure of a portable device for precise and rapid ice compress and pressurized drug delivery provided by an embodiment of the present invention installed on a patient;

Fig. 2 is a structural schematic view of the other side of the precise and rapid ice compress pressurized drug delivery portable device provided by the embodiment of the present invention installed on the patient;

Fig. 3 is a structural schematic diagram of the connection between the temperature-guiding and pressure-guiding module and the temperature-changing module of the portable device for accurate and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 4 is a structural schematic diagram of the other side of the connection between the temperature and pressure guiding module and the temperature changing module of the precise and rapid ice compressing pressurized drug delivery portable device provided by the embodiment of the present invention;

Fig. 5 is a schematic structural diagram of the temperature and pressure guiding module of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 6 is a cross-sectional view of the fitting plate of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 7 is a cross-sectional view of another laminating board of the precise and rapid ice compress pressurized drug delivery portable device provided by the embodiment of the present invention;

Fig. 8 is a structural schematic diagram of the strap assembly of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 9 is a schematic structural view of the airbag assembly of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 10 is a schematic structural view of the twisting assembly of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 11 is a schematic structural view of the Velcro component of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention;

Fig. 12 is a graph showing the temperature change of the temperature-changing module of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention in freezing mode;

Fig. 13 is a temperature change diagram of the temperature-changing module of the portable device for precise and rapid ice compress and pressurized drug delivery provided by the embodiment of the present invention in the heating mode;

In the figure 1, temperature guide and pressure guide module; 11, laminated plate; 12, connecting part; 13, flexible layer; 14, drug-loaded coating; 2, temperature variable module; 3, pressurized module; , hook; 312, hanging hole; 32, airbag component; 321, pressurized airbag; 322, inflatable equipment; 323, connecting belt; 324, trachea; 33, twisting component; ; 342 installation department; 343, Velcro hook surface.

Detailed ways

In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be described in detail below. Apparently, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other implementations obtained by persons of ordinary skill in the art without making creative efforts fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that, unless otherwise specified, "plurality" means two or more; the terms "upper", "lower", "left", "right", "inner" The orientation or positional relationship indicated by "," outer", "front end", "rear end", "head", "tail", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and Simplified descriptions, rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and thus should not be construed as limiting the invention. In addition, the terms "first", "second", "third", etc. are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

In the description of the present invention, it should also be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a flexible connection. Detachable connection, or integral connection; it can be mechanical connection or electrical connection; it can be direct connection or indirect connection through an intermediary. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

Example 1:

The present invention provides a portable device for accurate and rapid ice compressing and pressurized drug delivery, which includes a temperature guiding and pressure guiding module 1, a temperature changing module 2 and a pressurizing module 3, wherein the temperature guiding and pressure guiding module 1 is a solid piece, and the temperature and pressure guiding module The module 1 can be attached to the injured position of the patient, and the temperature and pressure guiding module 1 can be limited to the injured position of the patient through the pressurization module 3, and the pressurizing module 3 can apply pressure to the injured position of the patient through the temperature and pressure guiding module 1 , the temperature variable module 2 can transmit the generated energy to the patient's injured position through the temperature and pressure guiding module 1, the temperature variable module 2 and the temperature and pressure guiding module 1 are detachably connected, and the temperature variable module 2 needs to pass the generated energy within 48 hours of the patient's injury The cold energy stimulates the injured site, and after the 48-hour emergency period, the temperature-changing module 2 needs to generate heat to detumescence the injured site. The present invention provides a portable device for precise and rapid ice compressing and pressurized drug administration. When this product is in use, the pressurizing module 3, the temperature changing module 2 and the temperature and pressure guiding module 11 can be connected to form a module, and then the The module is attached to the injured site, and by changing the pressure value of the pressurizing module 3 , the pressure applied by the temperature conducting and pressure guiding module 1 to the injured site can be changed. Because of the non-destructive transferability of solid pressure, the pressure exerted by the temperature and pressure guiding module 1 on the injured site has a clear digital relationship with the pressure value given by the pressurization module 3, which is convenient for precise control of the pressure value; the ergonomics of the temperature and pressure guiding module 1 Therefore, the pressure is concentrated on the application area; the pressurization module 3 is a deformation force, non-gravity, and is not affected by the position of the body. Most daily activity scenes can also continue to pressurize, achieving a skin normal pressure of 0-100kpa. Since the temperature and pressure guiding module 1 in the module is a solid part and can be attached to the injured position, that is, the heat conduction coefficient of the path can be determined; the ergonomic characteristics of the temperature and pressure guiding module 1 and the pressure of the pressurizing module 3 , which increases the proportion of heat conduction paths, while in the traditional way, a large area of heat radiation phenomenon (microscopic angle) is caused by a large amount of air at the contact interface, that is, the path comprehensive thermal conductivity is larger, the thermal resistance is smaller, and it can be more Rapidly reduce the skin temperature to achieve controllable skin temperature (4-30°C); and the temperature variable module 2 is a controllable electric cooling module, the skin temperature can be easily controlled in seconds according to the application, and it is easy to realize the skin temperature (4-30°C ) is controllable; ergonomics and deformation pressurization, not affected by body position, most daily activity scenes can also be iced at the same time. Since the cooling and pressure guiding paths can share the same path, it also satisfies the time reuse problem of ice application and pressurization, and improves the timeliness. The ergonomic structure of the temperature conducting and pressure guiding module 1 can be operated by non-professionals within 10 seconds. The invention is easier to realize the application temperature gradient requirements and pressure gradient requirements of the epidermis, and solves the problem that the normal ice temperature of the application site is not low enough and the normal pressure is low when the ice compress and pressurization are applied to the injured position of the patient in the prior art. The operation is cumbersome and the treatment effect is relatively poor technical problem.

Example 2:

As an optional implementation, the shape of the fitting surface on the temperature conduction and pressure guiding module 1 conforms to ergonomics, and according to the difference of the injured part of the patient, the shape of the fitting surface on the temperature conducting and pressure guiding module 1 will conform to the injured part ergonomics. Furthermore, when the temperature and pressure guiding module 1 is pressurized at 10kpa for a normal person, more than 90% of the bonding surface of the temperature and pressure guiding module 1 will stick to the human skin. , this ergonomics needs to be between the skin and bones. It can also be considered that in the place where there is a lot of flesh in the injured position, the protruding arc of the fitting part of the corresponding position on the temperature and pressure guiding module 1 is relatively large. Where there is less meat, the protruding arc of the corresponding position on the temperature-conducting and pressure-conducting module 1 is relatively small, so that when the temperature-conducting and pressure-conducting module 1 is attached to the injured position, the temperature-conducting and pressure-conducting module 1 can be further strengthened. It is more convenient to compress human tissue, reduce the volume of human tissue (compared to the normal state), limit the volume of cyst cavity, increase the pressure of tissue fluid at the same time, reduce the pressure difference between blood and tissue fluid, and reduce internal bleeding resulting in swelling.

Example 3:

As an optional implementation, the temperature and pressure guiding module 1 is an integrally formed structure. The temperature and pressure guiding module 1 is a solid piece with low thermal resistance and high pressure guiding properties. It can further be made of metal materials. The process can be processed by CNC or Stamping; or, the temperature and pressure guiding module 1 is a mosaic structure, and the temperature and pressure guiding module 1 includes a plurality of mosaic units. By adjusting the mosaic units, the temperature and pressure guiding module 1 can further conform to the engineering structure of the human body , and is conducive to further fine-tuning the differential pressure requirements of various parts of the human body. Preferably, the temperature-conducting and pressure-conducting module 1 is made of magnesium alloy material, and the material used for the further temperature-conducting and pressure-conducting module 1 is JDBM magnesium alloy, which also has light weight. The characteristics and antibacterial properties make it easy to reduce the risk of bacteria during long-term wear. The temperature-conducting and pressure-conducting module 1 is a module with high thermal conductivity, and its overall thermal conductivity must be higher than 10W/m.k. The normal thickness of the temperature-conducting and pressure-conducting module 1 is less than 1cm.

Example 4:

As an optional embodiment, the temperature and pressure guiding module 1 includes a bonding plate 11 and a connecting portion 12, the bonding plate 11 is fixedly connected to one end surface of the connecting portion 12, and the other end surface of the connecting portion 12 can be detachably connected to the temperature variable module 2 , or the connection part 12 is connected with the pressure module 3, and the fitting plate 11 can be fitted on the injured position of the patient. The shape of the fitting plate 11 needs to be refined into ergonomics such as left and right ankles, left and right knee joints, and left and right radius according to different parts of the human body.

Example 5:

As an optional embodiment, a flexible layer 13 is also included. The flexible layer 13 is pasted on the bonding surface of the temperature conducting and pressure guiding module 1, and the flexible layer 13 can be directly bonded to the skin of the injured position. The flexible layer 13 needs to have good low thermal resistance and suitable softness. The preferred flexible layer 13 can be made of hydrogel material, which can improve the comfort of the patient. The elastic modulus of the flexible layer 13 is slightly higher than that of the skin, wherein the Young's elastic modulus of the flexible layer 13 ranges from 10 kPa to 100 kPa, and the thickness of the flexible layer 13 is less than 1 cm. The flexible layer 13 is to further improve the experience of the human body, enhance the closeness between the temperature guiding and pressure guiding module 1 and the use part, and at the same time, it also has a certain degree of elastic adjustment in the case of swelling and deformation of the use part.

In order to enhance the sense of experience, this module can be in contact with the human body, and a layer of flexible layer 13 should be adhered, which needs to have a good hydrogel material, and the hydrogel can also be the carrier of externally applied medicine here. During the cold pressurization process, certain drugs are transdermally administered.

Embodiment 6:

As an optional embodiment, a drug-loaded coating 14 is also included, and the drug-loaded coating 14 can be attached to human skin. In order to improve the time multiplexing effect, the drug-loaded coating is used to transdermally administer the drug while applying ice and pressure. There are three ways to implement, one is to directly add drug-loaded coating 14 on the lamination plate 11, the drug-loaded coating 14 is used for external application, and the drug-loaded coating 14 is directly attached to the skin; the other is to use a drug-loaded coating. The JDBM magnesium alloy is the laminated board 11; the third is to select the flexible layer 13 with externally applied medicine.

Embodiment 7:

As an optional embodiment, the temperature variable module 2 includes a housing, a semiconductor cooling chip, a first metal sheet, a second metal sheet, a control circuit, a temperature sensor and a data regulator, and the housing can be detachably connected to a temperature-conducting and pressure-conducting On the module 1, the semiconductor cooling plate, the first metal plate, the second metal plate, the control circuit and the temperature sensor are all located in the housing, the first metal plate is preferably JDBM magnesium alloy, and the first metal plate is connected to one end of the semiconductor cooling plate , the second metal sheet is connected to the other end of the semiconductor cooling chip, the data regulator is electrically connected to the temperature sensor, the semiconductor cooling chip, the control circuit is electrically connected to the data regulator, the control circuit can change the hot and cold ends of the semiconductor cooling chip, and the data The regulator can adjust the working temperature of the semiconducting refrigeration sheet. When the temperature variable module 2 is installed at the injured position, the temperature sensor can sense the temperature of the injured position, and at the same time, transmit the sensed temperature value to the data adjuster, and the data adjuster will adjust the work of the semiconductor refrigeration sheet according to the temperature value temperature. The first metal sheet is close to the temperature conduction and pressure conduction module 1 , and the second metal sheet is far away from the temperature conduction and pressure conduction module 1 . The temperature-variable module 2 can be used alone, or it can be used with the temperature-conducting and pressure-conducting module 1. Due to the existence of the temperature-conducting and pressure-conducting module 1, the transmitted energy will be lost in the two usage modes, so the temperature difference needs to be calculated through the data regulator. Compensation operation.

When the patient is injured within 48 hours, the control circuit controls the semiconductor cooling sheet so that the first metal sheet is connected to the cold end of the semiconductor cooling sheet, and the second metal sheet is connected to the hot end of the semiconductor cooling sheet, so the first metal sheet The radiated cold energy will be transferred to the injured position through the temperature and pressure guiding module 1; when the patient is injured after the 48-hour emergency period, by adjusting the control circuit, and then controlling the semiconductor refrigeration sheet, so that the first metal sheet and the semiconductor refrigeration sheet The hot end is connected, and the second metal sheet is connected to the cold end of the semiconductor refrigeration sheet, so the heat dissipated by the first metal sheet will be transferred to the injured position through the temperature-conducting and pressure-conducting module 1 .

The temperature variable module 2 has a freezing mode, a heating mode and a normal temperature mode. When the temperature variable module 2 is in the freezing mode, see Figure 12, the temperature of the human skin is between 4°C and 15°C, and Figure 12 shows one of the temperature variable module 2 and the skin temperature The temperature change curve with time is not limited to this kind of change curve in practice; when the temperature variable module 2 is in the heating mode, see Figure 13, the temperature of the human skin is between 39°C and 42°C, and Figure 13 shows the temperature variable module 2 and the skin A graph of temperature variation with time is not limited to this variation curve in practice; when the temperature variable module 2 is in the normal temperature mode, the temperature of the human skin is between 15°C and 39°C.

Embodiment 8:

As an optional embodiment, the temperature-changing module 2 is a box with a storage space, and ice cubes or reaction materials can be stored in the box. When in use, the box for storing ice cubes can emit cold energy and transfer it to the injured site; or the reaction material can undergo a heat-absorbing or exothermic chemical reaction after being placed in the box, and then the energy it generates Passed to the injured site, where the reaction material is not harmful to the human body.

Embodiment 9:

As an optional embodiment, the pressurization module 3 is a strap assembly 31 or an airbag assembly 32 or a twist assembly 33 or a Velcro assembly 34, which can make the injured position of the user move in different postures without affecting the practical effect; The number of pressure modules 3 is at least one, and multiple pressure modules 3 form an independent fine-tuning subsystem, which can precisely fine-tune the pressure distribution of details. ~100kpa. One end of the strap assembly 31 may be provided with a hook 311, and the other end may be provided with a plurality of hanging holes 312 at different positions, which are connected to different hanging holes 312 through the hook 311, so that the strap assembly 31 passes through the temperature-conducting and pressure-conducting module 1 The pressure exerted on the injured position is also different, and the part of the strap assembly 31 that bypasses the temperature and pressure guiding module 1 or the temperature variable module 2 can be fixed through the cover, so that the strap assembly 31 can be limited to the temperature and pressure guiding module 1 Or on the variable temperature module 2.

The airbag assembly 32 includes a pressurized airbag 321, an inflatable device 322 and a connection belt 323. The pressurized airbag 321 and the inflatable device 322 are connected through a trachea 324. Both sides of the pressurized airbag 321 are respectively connected with a connection belt 323, and the pressurized airbag 321 is released. On the temperature-guiding and pressure-guiding module 1 or the temperature-changing module 2, the connecting belts 323 on both sides bypass the human body and tie them together. The pressure exerted by the temperature conducting and pressure guiding module 1 on the injured site. The pressurization module 3 also includes a pressure sensor, which can sense the pressure exerted by the temperature conduction and pressure conduction module 1 on the injured site.

The twist assembly 33 includes a BOA knob buckle 331, an elastic cord 332 and a buckle 333. There are multiple buckles 333, and the BOA knob buckle 331 and the buckle 333 are connected by the elastic rope 332. By rotating the BOA knob buckle 331, the The tightness of the elastic rope 332 between the BOA knob buckle 331 and the buckle 333, when using the twist assembly 33, the BOA knob buckle 331 is connected to the temperature variable module 2, and the buckle 333 can be connected to the side of the temperature variable module 2 or On the temperature conducting and pressure guiding module 1, the elastic cord 332 needs to bypass the injured position of the patient and be connected with the BOA knob buckle 331 and the buckle 333, and the pressure can be changed by rotating the BOA knob buckle 331.

The Velcro component 34 includes an elastic strap 341 , a mounting portion 342 , a Velcro hook surface 343 , and the elastic strap 343 . The elastic strap 341 is an elastic strap with sanding, which is the carrier of all components and provides variable pressure according to the degree of deformation. The installation part 342 is fixedly connected to the middle part of the elastic strap 341. The temperature guiding module 1 is connected, and the Velcro hook surface 343 is fixedly connected to one end of the elastic strap 341 , and the Velcro hook surface 343 can be pasted and connected to the back surface of the elastic strap 341 .

As an optional embodiment, it also includes a cover, which can cover a part of the pressurization module 3 and can be detachably connected with the temperature variable module 2; or, the cover can cover a part of the pressurization module 3 and can be connected with the guide The temperature guiding module 1 is detachably connected.

Example 10:

There are two modes of use in the present invention, one is to use the temperature variable module 2 alone, and directly tie the temperature variable module 2 to the injured position of the patient through the pressurization module 3, this mode is only used for the relatively flat injured position; the other is the temperature variable module 2 is used in combination with the temperature conduction and pressure conduction module 1, and this mode is used for any injured position.

The above is only a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Anyone skilled in the art can easily think of changes or substitutions within the technical scope disclosed in the present invention. Should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

A portable device for precise and rapid ice compressing pressurized drug administration, characterized in that it includes a temperature conducting and pressure guiding module (1), a temperature changing module (2) and a pressurizing module (3), wherein,

The temperature-guiding and pressure-guiding module (1) is a solid part, the temperature-guiding and pressure-guiding module (1) can be attached to the injured position of the patient, and the temperature-guiding and pressure-guiding module (1) passes through the pressurizing module ( 3) Can be limited to the injured position of the patient, the pressurization module (3) can apply pressure to the injured position of the patient through the temperature conduction and pressure conduction module (1), and the temperature variable module (2) can The generated energy is transmitted to the injured position of the patient through the temperature conducting and pressure guiding module (1), and the temperature changing module (2) is detachably connected with the temperature guiding and pressure guiding module (1).
According to claim 1, the portable device for accurate and rapid ice compress pressurized drug delivery is characterized in that the shape of the bonding surface on the temperature guiding and pressure guiding module (1) conforms to ergonomics.
According to claim 1, the precise and rapid ice compressing pressurized drug delivery portable device is characterized in that, the temperature-guiding and pressure-guiding module (1) is an integrated structure; or, the temperature-guiding and pressure-guiding module (1) is Mosaic structure; the thermal conductivity of the temperature and pressure guiding module (1) is greater than 10W/m·k; the normal thickness of the temperature and pressure guiding module (1) is less than 1cm; the temperature and pressure guiding module (1) The material used is JDBM magnesium alloy.
According to claim 1, the portable device for accurate and rapid ice compress pressurization and drug delivery is characterized in that, the temperature-conducting and pressure-conducting module (1) includes a bonding plate (11) and a connecting part (12), and the bonding plate ( 11) It is fixedly connected to one end surface of the connecting part (12), and the other end surface of the connecting part (12) can be detachably connected to the temperature variable module (2), or the connecting part (12) is connected to the The pressure module (3) is connected, and the bonding plate (11) can be bonded to the injured position of the patient.
According to claim 1, the portable device for precise and rapid ice compress, pressurized drug delivery is characterized in that it also includes a flexible layer (13), and the flexible layer (13) is pasted on the temperature guide and pressure guide module (1). Fitting surface;

The Young's modulus of elasticity of the flexible layer (13) ranges from 10kpa to 100kpa, and the thickness of the flexible layer (13) is less than 1cm.
According to claim 3 or 5, the precise and rapid ice compress pressurized drug delivery portable device is characterized in that it also includes a drug-loaded coating (14), and the drug-loaded coating (14) is used to fit on human skin superior.
According to claim 1, the portable device for precise and rapid ice compress, pressurized drug delivery is characterized in that, the temperature changing module (2) includes a shell, a semiconductor refrigeration chip, a first metal sheet, a second metal sheet, a control circuit, A temperature sensor and a data regulator, the housing can be detachably connected to the temperature conduction and pressure conduction module (1), the semiconductor refrigeration sheet, the first metal sheet, the second metal sheet, the control circuit and the The temperature sensors are all located in the housing, the first metal sheet is connected to one end of the semiconductor cooling sheet, the second metal sheet is connected to the other end of the semiconductor cooling sheet, the data adjuster and the The temperature sensor is electrically connected, the semiconductor cooling chip, the control circuit and the data adjuster are electrically connected, the control circuit can change the hot and cold ends of the semiconductor cooling chip, and the data adjuster can adjust the The working temperature of the semiconductor refrigerator;

The temperature variable module (2) has a freezing mode, a heating mode, and a normal temperature mode. When the temperature variable module (2) is in the freezing mode, the temperature of the human skin is between 4°C and 15°C; when the temperature variable module (2) In the heating mode, the temperature of the human skin is between 39°C and 42°C; when the temperature variable module (2) is in the normal temperature mode, the temperature of the human skin is between 15°C and 39°C.
According to claim 1, the portable device for precise and rapid ice compress, pressurized drug delivery is characterized in that, the temperature-changing module (2) is a box body with a storage space, and ice cubes or reaction materials can be stored in the box body .
According to claim 1, the portable device for precise and rapid ice compress pressurization administration is characterized in that, the pressurization module (3) is a strap assembly (31) or an airbag assembly (32) or a twist assembly (33) or Velcro component (34);

The number of the pressurization module (3) is at least one;

The normal pressure applied by the pressurizing module (3) to the temperature conducting and pressure conducting module (1) ranges from 0 to 100kpa.
According to claim 1, the portable device for precise and rapid ice compress and pressurized drug delivery is characterized in that it also includes a cover, and the cover can cover a part of the pressurization module (3) and can be connected with the temperature changing module (2) Detachable connection; or, the cover can cover a part of the pressurization module (3) and can be detachably connected with the temperature and pressure conduction module (1).