WO2023108483A1 - 大鼠颈静脉取血固定装置 - Google Patents

大鼠颈静脉取血固定装置 Download PDF

Info

Publication number
WO2023108483A1
WO2023108483A1 PCT/CN2021/138358 CN2021138358W WO2023108483A1 WO 2023108483 A1 WO2023108483 A1 WO 2023108483A1 CN 2021138358 W CN2021138358 W CN 2021138358W WO 2023108483 A1 WO2023108483 A1 WO 2023108483A1
Authority
WO
WIPO (PCT)
Prior art keywords
blood taking
jugular vein
vein blood
rat
forelimb
Prior art date
Application number
PCT/CN2021/138358
Other languages
English (en)
French (fr)
Inventor
张路
Original Assignee
深圳先进技术研究院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳先进技术研究院 filed Critical 深圳先进技术研究院
Priority to PCT/CN2021/138358 priority Critical patent/WO2023108483A1/zh
Publication of WO2023108483A1 publication Critical patent/WO2023108483A1/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00—Appliances for supporting or fettering animals for operative purposes

Definitions

  • the invention relates to a rat jugular vein blood taking fixation device.
  • the blood collection process in rats is difficult.
  • blood collection from the canthal sinus and femoral vein have the problems of small blood collection and low repetition times.
  • the method of blood collection from the jugular sinus is simple and repeatable. See Figure 1.
  • the rat In the existing process of taking blood from the jugular vein, the rat needs to lie flat, one person manually stretches the rat's hands to expose the position of the venous sinus, and the other person inserts the needle from the top of the rat's head parallel to the rat's body position to take the blood. Blood.
  • This method requires the cooperation of two people, and it is easy for the rat to bite the needle or the staff's finger.
  • the present invention proposes a rat jugular vein blood collection fixation device, which has a simple structure and is easy to manufacture, and only one person can complete the blood collection.
  • a rat jugular vein blood taking fixation device which is special in that:
  • It includes two forelimb fixing blocks with the same structure, and the two forelimb fixing blocks are arranged oppositely;
  • the forelimb fixing block includes a base and a fixing arm, and the fixing arm is arranged above the base.
  • the base is a prism structure
  • the prism structure includes a first slope
  • the first slopes on the bases of the two forelimb fixing blocks are oppositely arranged
  • the fixing arms are arranged in the opposite direction of the first slope.
  • a hood is also included, the hood is a trumpet-shaped structure, and a rod-shaped fixing section is provided at the rear end of the horn-shaped structure.
  • the two fixed arms are respectively used to fix the forelimbs of the rat, the gap formed by the two first slopes is used to place the back and neck of the rat, and the head shield is used to limit the movement of the rat's head to prevent it from biting the needle or the staff finger.
  • a base plate is also included, and the bases of the two forelimb fixing blocks are respectively connected to the base plate.
  • the bases of the two forelimb fixing blocks are respectively fixedly connected with the bottom plate.
  • the base of one forelimb fixing block is fixedly connected to the base plate, and the base of the other forelimb fixing block is connected to the base plate through a dovetail groove structure, so as to facilitate adjustment of the distance between the two and facilitate corresponding to rats of different sizes.
  • the bases of the two forelimb fixing blocks are respectively connected to the base plate through the dovetail groove structure, and the two forelimb fixing blocks can move relatively along the dovetail groove, and the distance between them can be adjusted to facilitate corresponding to rats of different sizes.
  • the base plate is provided with a U-shaped block, one side of the U-shaped block is provided with a fastening screw, the fastening screw is connected with the U-shaped block through a threaded connection, the fixed section of the hood is located on the U-shaped block, and the fastened Clamp the fixed section of the hood with the set screw.
  • the bottom of the U-shaped block is connected to the bottom plate through a dovetail groove structure.
  • the trumpet-shaped structure of the hood is made of transparent material.
  • the bottom plate is an acrylic plate.
  • the rat jugular vein blood collection fixture proposed by the present invention has a simple structure, is easy to manufacture, and has low production cost; only one person can complete the blood collection, saving labor; the hood can prevent rats from biting needles or staff fingers , to avoid injury to the staff, and at the same time ensure the smooth progress of the blood collection work.
  • Fig. 1 is an operation diagram that requires two people to take blood from the jugular sinus of the existing rat;
  • Fig. 2 is a structural schematic diagram of a rat jugular vein blood taking fixture of the present invention
  • Fig. 3 is a schematic diagram of another direction of a rat jugular vein blood taking and fixing device of the present invention.
  • Fig. 4 is a schematic diagram of the hood in Fig. 3;
  • Fig. 5 is a perspective view of the forelimb fixing block.
  • a rat jugular vein blood sampling fixation device includes two forelimb fixation blocks 1 with the same structure, and the two forelimb fixation blocks 1 are arranged opposite to each other.
  • the forelimb fixing block 1 includes a base 2 and a fixed arm 3 , and the fixed arm 3 is arranged above the base 2 .
  • the base 2 is a truss structure, and the truss structure includes a first slope 4, and the first slopes 4 on the bases 2 of the two forelimb fixing blocks 1 are oppositely arranged.
  • the fixed arm 3 is arranged in the opposite direction of the first slope 4 .
  • FIG. 2 and FIG. 3 it also includes a hood 5 , which is a trumpet-shaped structure, and a rod-shaped fixing section 6 is provided at the rear end of the horn-shaped structure.
  • FIG. 2 and FIG. 3 it also includes a base plate 7 , and the bases 2 of the two forelimb fixing blocks 1 are respectively connected to the base plate 7 .
  • the bases 2 of the two forelimb fixing blocks 1 are respectively fixedly connected to the bottom plate 7 .
  • the base 2 of one forelimb fixing block 1 is fixedly connected with the base plate 7, and the base 2 of the other forelimb fixing block 1 is connected with the base plate 7 through a dovetail groove structure, so as to facilitate adjustment of the distance between the two. It is convenient for rats of different sizes.
  • the bases 2 of the two forelimb fixing blocks 1 are respectively connected to the bottom plate 7 through the dovetail groove structure, and the two forelimb fixing blocks 1 can move relatively along the dovetail groove, and the adjustment between the two The distance between them is convenient for rats of different sizes.
  • a U-shaped block 8 is provided on the base plate 7, and a fastening screw 9 is provided on one side of the U-shaped block 8, and the fastening screw 9 is threaded. It is connected with the U-shaped block 8, the fixed section of the head cover 5 is located on the U-shaped block 8, and the fastening screw 9 clamps the fixed section of the head cover 5.
  • the bottom of the U-shaped block 8 is connected to the bottom plate 7 through a dovetail groove structure.
  • the trumpet-shaped structure of the hood 5 is made of transparent material.
  • a rat jugular vein blood sampling fixation device includes two forelimb fixation blocks 1 with the same structure, a head cover 5, and a bottom plate 7, and the two forelimb fixation blocks 1 are arranged oppositely.
  • the forelimb fixing block 1 includes a base 2 and a fixed arm 3 , and the fixed arm 3 is arranged above the base 2 .
  • the base 2 is a truss structure
  • the truss structure includes a first slope 4
  • the first slope 4 on the base 2 of the two forelimb fixing blocks 1 is oppositely arranged
  • the fixed arm 3 is on the first slope 4 Opposite direction setting.
  • the hood 5 is a horn-shaped structure, and the rear end of the horn-shaped structure is provided with a rod-shaped fixing section 6 .
  • the bases 2 of the two forelimb fixing blocks 1 are respectively connected to the bottom plate 7 through the dovetail groove structure, and the two forelimb fixing blocks 1 can move relatively along the dovetail groove, and the distance between the two can be adjusted to facilitate the correspondence of different sizes.
  • the base plate 7 is provided with a U-shaped block 8, and one side of the U-shaped block 8 is provided with a fastening screw 9, and the fastening screw 9 is connected with the U-shaped block 8 through a threaded connection.
  • the fixed section of 5 is located on the U-shaped block 8, and the fastening screw 9 clamps the fixed section of the head cover 5.
  • the bottom of the U-shaped block 8 is connected to the bottom plate 7 through a dovetail groove structure.
  • the trumpet-shaped structure of the hood 5 is made of transparent material.
  • Base plate 7 is an acrylic plate.
  • the using method of the present invention is:

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

本发明涉及一种大鼠颈静脉取血固定装置，包括两个结构相同的前肢固定块，两个前肢固定块相对设置；所述前肢固定块包括底座和固定臂，固定臂设置在底座的上方。本发明提出的一种大鼠颈静脉取血固定装置，结构简单，易于制作，制作成本低；只需一人便可完成取血,节省劳动力；头罩可以防止大鼠撕咬针头或者工作人员手指，避免工作人员受伤，同时保证取血工作顺利进行。

Description

大鼠颈静脉取血固定装置 技术领域
本发明涉及一种大鼠颈静脉取血固定装置。
背景技术
大鼠取血过程困难，常用办法中，眦静脉窦取血和股静脉取血等方法都有取血量少且重复次数低等问题，颈静脉窦取血的方法简单可重复性高。参见图1，现有的颈静脉取血过程中，需要使大鼠平躺，一人人工将大鼠双手撑开，暴露静脉窦位置，另一人从大鼠头顶方向平行大鼠躯体位置入针取血。这种方法需要两人配合完成，且容易出现大鼠撕咬针头或者工作人员手指的现象。
发明内容
为了克服上述现有技术中存在的问题，本发明提出一种大鼠颈静脉取血固定装置，结构简单，易于制作，只需一人便可完成取血。
本发明解决上述问题的技术方案是：一种大鼠颈静脉取血固定装置，其特殊之处在于：
包括两个结构相同的前肢固定块，两个前肢固定块相对设置；
所述前肢固定块包括底座和固定臂，固定臂设置在底座的上方。
优选的，底座为棱台结构，棱台结构上包括第一斜面，两个前肢固定块的底座上的第一斜面相对设置，固定臂在第一斜面的相反方向设置。
优选的，还包括头罩，头罩为喇叭状结构，喇叭状结构后端设有杆状固定段。
两个固定臂分别用于固定大鼠的前肢，两个第一斜面形成的空隙放置大鼠的背部和颈部，头罩用于限制大鼠头部的移动，防止其撕咬针头或者工作人员手指。
优选的，还包括底板，两个前肢固定块的底座分别与底板连接。
优选的，两个前肢固定块的底座分别与底板固定连接。
优选的，一个前肢固定块的底座与底板固定连接，另一个前肢固定块的底座通过燕尾槽结构与底板连接，便于调整二者之间的距离，便于对应不同大小的大鼠。
优选的，两个前肢固定块的底座分别通过燕尾槽结构与底板连接，两个前肢固定块沿着燕尾槽可以相对移动，调整二者之间的距离，便于对应不同大小的大鼠。
优选的，所述底板上设有U型块，U型块的一侧设有紧固螺钉，紧固螺钉通过螺纹连接方式与U型块连接，头罩的固定段位于U型块上，紧固螺钉对头罩的固定段进行夹紧。
优选的，所述U型块底部通过燕尾槽结构与底板连接。
优选的，所述头罩的喇叭状结构为透明材质制成。
优选的，所述底板为亚克力板。
本发明的优点：
本发明提出的一种大鼠颈静脉取血固定装置，结构简单，易于制作，制作成本低；只需一人便可完成取血,节省劳动力；头罩可以防止大鼠撕咬针头或者工作人员手指，避免工作人员受伤，同时保证取血工作顺利进行。
附图说明
图1为现有大鼠颈静脉窦取血需要双人进行操作图；
图2为本发明一种大鼠颈静脉取血固定装置结构示意图；
图3为本发明一种大鼠颈静脉取血固定装置另一个方向示意图；
图4为图3中头罩示意图；
图5为前肢固定块的立体图。
其中：1、前肢固定块，2、底座，3、固定臂，4、第一斜面，5、头罩，6、杆状固定段，7、底板，8、U型块，9、紧固螺钉。
具体实施方式
为使本发明实施方式的目的、技术方案和优点更加清楚，下面将结合本发 明实施方式中的附图，对本发明实施方式中的技术方案进行清楚、完整地描述，显然，所描述的实施方式是本发明一部分实施方式，而不是全部的实施方式。基于本发明中的实施方式，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施方式，都属于本发明保护的范围。因此，以下对在附图中提供的本发明的实施方式的详细描述并非旨在限制要求保护的本发明的范围，而是仅仅表示本发明的选定实施方式。
参见图2-图5，一种大鼠颈静脉取血固定装置，包括两个结构相同的前肢固定块1，两个前肢固定块1相对设置。所述前肢固定块1包括底座2和固定臂3，固定臂3设置在底座2的上方。
作为本发明的一个优选实施例，参见图5，所述底座2为棱台结构，棱台结构上包括第一斜面4，两个前肢固定块1的底座2上的第一斜面4相对设置，固定臂3在第一斜面4的相反方向设置。
作为本发明的一个优选实施例，参见图2和图3，还包括头罩5，头罩5为喇叭状结构，喇叭状结构后端设有杆状固定段6。
作为本发明的一个优选实施例，参见图2和图3，还包括底板7，两个前肢固定块1的底座2分别与底板7连接。
作为本发明的一个优选实施例，参见图2，两个前肢固定块1的底座2分别与底板7固定连接。
作为本发明的一个优选实施例，一个前肢固定块1的底座2与底板7固定连接，另一个前肢固定块1的底座2通过燕尾槽结构与底板7连接，便于调整二者之间的距离，便于对应不同大小的大鼠。
作为本发明的一个优选实施例，参见图3，两个前肢固定块1的底座2分别通过燕尾槽结构与底板7连接，两个前肢固定块1沿着燕尾槽可以相对移动，调整二者之间的距离，便于对应不同大小的大鼠。
作为本发明的一个优选实施例，参见图2和图3，所述底板7上设有U型块8，U型块8的一侧设有紧固螺钉9，紧固螺钉9通过螺纹连接方式与U型块 8连接，头罩5的固定段位于U型块8上，紧固螺钉9对头罩5的固定段进行夹紧。
优选地，所述U型块8底部通过燕尾槽结构与底板7连接。所述头罩5的喇叭状结构为透明材质制成。
实施例
参见图2-图5，一种大鼠颈静脉取血固定装置，包括两个结构相同的前肢固定块1、头罩5、底板7，两个前肢固定块1相对设置。所述前肢固定块1包括底座2和固定臂3，固定臂3设置在底座2的上方。
参见图5，所述底座2为棱台结构，棱台结构上包括第一斜面4，两个前肢固定块1的底座2上的第一斜面4相对设置，固定臂3在第一斜面4的相反方向设置。头罩5为喇叭状结构，喇叭状结构后端设有杆状固定段6。
参见图3，两个前肢固定块1的底座2分别通过燕尾槽结构与底板7连接，两个前肢固定块1沿着燕尾槽可以相对移动，调整二者之间的距离，便于对应不同大小的大鼠。参见图2和图3，所述底板7上设有U型块8，U型块8的一侧设有紧固螺钉9，紧固螺钉9通过螺纹连接方式与U型块8连接，头罩5的固定段位于U型块8上，紧固螺钉9对头罩5的固定段进行夹紧。所述U型块8底部通过燕尾槽结构与底板7连接。所述头罩5的喇叭状结构为透明材质制成。底板7为亚克力板。
本发明的使用方法为：
将大鼠平躺，将一个前肢用皮筋固定在一个前肢固定块1的固定臂3上，大鼠的背部紧贴前肢固定块1上固定第一斜面4，挪动另一个前肢固定块1，使大鼠的背部紧贴其第一斜面4，再将另一个前肢用皮筋固定在固定臂3上，移动U型块8，使面罩正对大鼠的头部，根据实际情况移动杆状固定段6，使大鼠头部进入面罩5内，固定紧固螺钉9。此时大鼠已固定好，可以进行颈静脉窦取血。
以上所述仅为本发明的实施例，并非以此限制本发明的保护范围，凡是利用本发明说明书及附图内容所作的等效结构或等效流程变换，或直接或间接运 用在其他相关的系统领域，均同理包括在本发明的保护范围内。

Claims (10)

  1. 一种大鼠颈静脉取血固定装置，其特征在于：
    包括两个结构相同的前肢固定块(1)，两个前肢固定块(1)相对设置；
    所述前肢固定块(1)包括底座(2)和固定臂(3)，固定臂(3)设置在底座(2)的上方。
  2. 根据权利要求1所述的一种大鼠颈静脉取血固定装置，其特征在于：
    所述底座(2)为棱台结构，棱台结构上包括第一斜面(4)，两个前肢固定块(1)的底座(2)上的第一斜面(4)相对设置，固定臂(3)在第一斜面(4)的相反方向设置。
  3. 根据权利要求2所述的一种大鼠颈静脉取血固定装置，其特征在于：
    还包括头罩(5)，头罩(5)为喇叭状结构，喇叭状结构后端设有杆状固定段(6)。
  4. 根据权利要求3所述的一种大鼠颈静脉取血固定装置，其特征在于：
    还包括底板(7)，两个前肢固定块(1)的底座(2)分别与底板(7)连接。
  5. 根据权利要求4所述的一种大鼠颈静脉取血固定装置，其特征在于：
    两个前肢固定块(1)的底座(2)分别与底板(7)固定连接。
  6. 根据权利要求4所述的一种大鼠颈静脉取血固定装置，其特 征在于：
    一个前肢固定块(1)的底座(2)与底板(7)固定连接，另一个前肢固定块(1)的底座(2)通过燕尾槽结构与底板(7)连接，便于调整二者之间的距离，便于对应不同大小的大鼠。
  7. 根据权利要求4所述的一种大鼠颈静脉取血固定装置，其特征在于：
    两个前肢固定块(1)的底座(2)分别通过燕尾槽结构与底板(7)连接，两个前肢固定块(1)沿着燕尾槽可以相对移动，调整二者之间的距离，便于对应不同大小的大鼠。
  8. 根据权利要求4-7任一所述的一种大鼠颈静脉取血固定装置，其特征在于：
    所述底板(7)上设有U型块(8)，U型块(8)的一侧设有紧固螺钉(9)，紧固螺钉(9)通过螺纹连接方式与U型块(8)连接，头罩(5)的固定段位于U型块(8)上，紧固螺钉(9)对头罩(5)的固定段进行夹紧。
  9. 根据权利要求8所述的一种大鼠颈静脉取血固定装置，其特征在于：
    所述U型块(8)底部通过燕尾槽结构与底板(7)连接。
  10. 根据权利要求9所述的一种大鼠颈静脉取血固定装置，其特征在于：
    所述头罩(5)的喇叭状结构为透明材质制成。
PCT/CN2021/138358 2021-12-15 2021-12-15 大鼠颈静脉取血固定装置 WO2023108483A1 (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2021/138358 WO2023108483A1 (zh) 2021-12-15 2021-12-15 大鼠颈静脉取血固定装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2021/138358 WO2023108483A1 (zh) 2021-12-15 2021-12-15 大鼠颈静脉取血固定装置

Publications (1)

Publication Number Publication Date
WO2023108483A1 true WO2023108483A1 (zh) 2023-06-22

Family

ID=86775015

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2021/138358 WO2023108483A1 (zh) 2021-12-15 2021-12-15 大鼠颈静脉取血固定装置

Country Status (1)

Country Link
WO (1) WO2023108483A1 (zh)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584609A (zh) * 2009-06-26 2009-11-25 河南中医学院 实验专用持鼠器
CN211534977U (zh) * 2020-02-05 2020-09-22 青岛市食品药品检验研究院（青岛市药品不良反应监测中心、青岛市实验动物和动物实验中心） 一种可调式大鼠固定器
CN111743656A (zh) * 2019-03-27 2020-10-09 王彤 一种基于3d打印技术的实验用兔子固定装置及其制备方法
US20210121277A1 (en) * 2016-07-22 2021-04-29 The Royal Institution For The Advancement Of Learning/Mcgill University Device, method, and system for restraining an animal in a fixed position for a medical procedure
CN213217848U (zh) * 2020-05-11 2021-05-18 湖北天勤生物科技有限公司 一种大鼠颈静脉采血固定器
CN214908595U (zh) * 2021-07-20 2021-11-30 拜澳泰克(沈阳)生物医学集团有限公司 实验大小鼠通用固定装置

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584609A (zh) * 2009-06-26 2009-11-25 河南中医学院 实验专用持鼠器
US20210121277A1 (en) * 2016-07-22 2021-04-29 The Royal Institution For The Advancement Of Learning/Mcgill University Device, method, and system for restraining an animal in a fixed position for a medical procedure
CN111743656A (zh) * 2019-03-27 2020-10-09 王彤 一种基于3d打印技术的实验用兔子固定装置及其制备方法
CN211534977U (zh) * 2020-02-05 2020-09-22 青岛市食品药品检验研究院（青岛市药品不良反应监测中心、青岛市实验动物和动物实验中心） 一种可调式大鼠固定器
CN213217848U (zh) * 2020-05-11 2021-05-18 湖北天勤生物科技有限公司 一种大鼠颈静脉采血固定器
CN214908595U (zh) * 2021-07-20 2021-11-30 拜澳泰克(沈阳)生物医学集团有限公司 实验大小鼠通用固定装置

Similar Documents

Publication Publication Date Title
CN103462675A (zh) 单边双轨组合式骨外固定装置
WO2023108483A1 (zh) 大鼠颈静脉取血固定装置
CN107198557A (zh) 一种桡动脉穿刺专用的固定装置
CN213047179U (zh) 一种取皮辅助器
MY104848A (en) Connecting device for shuttering panels
CN106667645A (zh) 一种新型骨科夹板
CN205514693U (zh) 鲟鱼脑组织样品取样台
CN205947852U (zh) 一种复合型骨科取钉装置接头
CN219021680U (zh) 一种便于眼球采血和腹部注射的老鼠固定装置
CN210843357U (zh) 一种老年人浅静脉辅助穿刺装置
CN209405243U (zh) 一种腹部辅灸固定装置
CN210114732U (zh) 一种脑出血穿刺引流定位装置
CN108375671A (zh) 一种血液分析仪
CN114191138A (zh) 大鼠颈静脉取血固定装置
CN214970913U (zh) 新型多功能胸管固定联合夹管装置
CN215136078U (zh) 一种祛斑用的多功能多波长激光探头
US2360738A (en) Surgeon's tool
CN215228317U (zh) 一种骨折复位固定导向器
CN218792930U (zh) 一种便于进行调节的换药辅助装置
CN215839784U (zh) 一种小儿骨科治疗用悬吊牵引带组件
CN210330892U (zh) 一种新型眼科手术镊
CN211023026U (zh) 一种外固定支架
CN209701141U (zh) 一种中医针剂盒
JPS64897Y2 (zh)
CN215018131U (zh) 一种辅助肌腱缝合的牵拉固定器

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21967620

Country of ref document: EP

Kind code of ref document: A1