WO2023087183A1 - Method for typing chamber angle closure mechanism of primary angle closure glaucoma - Google Patents

Method for typing chamber angle closure mechanism of primary angle closure glaucoma Download PDF

Info

Publication number
WO2023087183A1
WO2023087183A1 PCT/CN2021/131258 CN2021131258W WO2023087183A1 WO 2023087183 A1 WO2023087183 A1 WO 2023087183A1 CN 2021131258 W CN2021131258 W CN 2021131258W WO 2023087183 A1 WO2023087183 A1 WO 2023087183A1
Authority
WO
WIPO (PCT)
Prior art keywords
angle
typing
image
anterior segment
result
Prior art date
Application number
PCT/CN2021/131258
Other languages
French (fr)
Chinese (zh)
Inventor
张烨
李树宁
张青
张潇月
Original Assignee
首都医科大学附属北京同仁医院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 首都医科大学附属北京同仁医院 filed Critical 首都医科大学附属北京同仁医院
Priority to PCT/CN2021/131258 priority Critical patent/WO2023087183A1/en
Publication of WO2023087183A1 publication Critical patent/WO2023087183A1/en

Links

Images

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/20Image preprocessing
    • G06V10/25Determination of region of interest [ROI] or a volume of interest [VOI]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/70Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/82Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V40/00Recognition of biometric, human-related or animal-related patterns in image or video data
    • G06V40/10Human or animal bodies, e.g. vehicle occupants or pedestrians; Body parts, e.g. hands
    • G06V40/18Eye characteristics, e.g. of the iris

Abstract

The present application discloses a method for typing a chamber angle closure mechanism of primary angle closure glaucoma. The method comprises: obtaining an anterior segment cross-sectional image to be typed; performing chamber angle feature detection on the anterior segment cross-sectional image to obtain a chamber angle feature region image; inputting the chamber angle feature region image into a preset first typing network model to obtain a first typing result; transforming the chamber angle feature region image into a heat map, and inputting the heat map obtained by transformation and the anterior segment cross-sectional image into a preset second typing network model to obtain a second typing result; and analyzing the first typing result and the second typing result to obtain a typing result of the anterior segment cross-sectional image. In the present application, by processing the anterior segment cross-sectional image in two different modes and performing analysis to obtain a final result, the accuracy of typing is improved, and convenience is brought to a doctor for subsequent diagnosis; moreover, typing processing can be quickly performed on the image by means of the typing network models, thereby improving the efficiency of typing.

Description

一种原发性闭角型青光眼的房角关闭机制分型方法A classification method of angle closure mechanism in primary angle-closure glaucoma 技术领域technical field
本申请涉及医学图像处理技术领域,具体涉及一种原发性闭角型青光眼的房角关闭机制分型方法。The present application relates to the technical field of medical image processing, in particular to a method for typing the angle closure mechanism of primary angle-closure glaucoma.
背景技术Background technique
青光眼是全球范围内第一位不可逆性致盲眼病。其中原发性闭角型青光眼(简称闭青)在我国的患病人数居全球首位。我国闭青的发病机制不同于西方人,房角关闭机制除瞳孔阻滞机制外,尚存在非瞳孔阻滞因素,呈多样性,且有些病例可能是两种机制或多种机制共同存在。建立闭青的房角关闭机制分型有助于对不同房角关闭机制的闭青进行有针对性的个性化治疗,并且有助于对不同房角关闭机制的闭青致病危险因素的探索,并建立闭青发病和病情进展的预测模型。Glaucoma is the first irreversible blinding eye disease worldwide. Among them, the number of patients with primary angle-closure glaucoma (abbreviated as closed glaucoma) ranks first in the world in my country. The pathogenesis of closed eyes in my country is different from that of Westerners. In addition to the pupillary block mechanism, there are still non-pupil block factors in the angle closure mechanism, which is diverse, and in some cases, two mechanisms or more mechanisms may co-exist. The establishment of the classification of angle closure mechanism of closed eyes is helpful for targeted and individualized treatment of closed eyes with different angle closing mechanisms, and it is helpful for the exploration of risk factors for different angle closing mechanisms of closed eyes , and establish a prediction model for the onset and progression of the disease.
现有的房角关闭机制的分型方法为医生或研究者主导完成的,具有较强的主观性。此外,由于我国闭青患者房角关闭机制的复杂性,在主要通过医生的主观判断进行分型的情况下,由于医生判断过程可能会消耗大量的时间,导致整个分型过程效率低,无法为医生的诊断提供有力的帮助,不适于临床及研究中的广泛推广应用。The existing classification methods of angle closure mechanism are completed by doctors or researchers, and are highly subjective. In addition, due to the complexity of the chamber angle closure mechanism of patients with closed eyes in my country, in the case of classification mainly through the doctor's subjective judgment, the doctor's judgment process may consume a lot of time, resulting in low efficiency of the entire classification process, which cannot be used for classification. The doctor's diagnosis provides powerful help, and it is not suitable for widespread application in clinical and research.
发明内容Contents of the invention
有鉴于此,本申请实施例提供了一种原发性闭角型青光眼的房角关闭机制分型方法,以解决现有分型方法分型效率低的问题。In view of this, the embodiment of the present application provides a method for typing the angle closure mechanism of primary angle-closure glaucoma, so as to solve the problem of low typing efficiency of the existing typing methods.
为达到上述目的,本申请提供如下技术方案:In order to achieve the above object, the application provides the following technical solutions:
本申请实施例提供了一种原发性闭角型青光眼的房角关闭机制分型方法,包括:The embodiment of the present application provides a method for typing the angle closure mechanism of primary angle-closure glaucoma, including:
获取待分型的眼前节横断面图像;Obtain cross-sectional images of the anterior segment to be classified;
对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像;Performing a feature detection of the room angle on the anterior segment cross-sectional image to obtain a room angle feature region image;
将所述房角特征区域图像输入预设的第一分型网络模型得到第一分型结果;Inputting the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result;
对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果;Transforming the image of the characteristic area of the chamber angle into a thermal map, and inputting the converted thermal image and the anterior segment cross-sectional image into a preset second classification network model to obtain a second classification result;
对所述第一分型结果和第二分型结果进行分析,得到所述眼前节横断面图像的分型结果。The first typing result and the second typing result are analyzed to obtain the typing result of the anterior segment cross-sectional image.
可选的,对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像,包括:Optionally, the feature detection of the room angle is performed on the cross-sectional image of the anterior segment to obtain the image of the room angle feature area, including:
对所述眼前节横断面图像进行房角的特征检测,得到第一房角特征区域图像和第二房角特征区域图像;Performing a feature detection of the room angle on the cross-sectional image of the anterior segment to obtain a first room angle feature area image and a second room angle feature area image;
将所述第一房角特征区域图像和第二房角特征区域图像进行组合,得到房角特征区域图像。Combining the first image of the characteristic region of the chamber angle with the image of the second characteristic region of the chamber angle to obtain the image of the characteristic region of the chamber angle.
可选的,对所述眼前节横断面图像进行房角的特征检测,得到第一房角特征区域图像和第二房角特征区域图像,包括:Optionally, the feature detection of the room angle is performed on the cross-sectional image of the anterior segment to obtain the first room angle feature area image and the second room angle feature area image, including:
对所述眼前节横断面图像进行房角的特征检测,得到第一房角区域和第二房角区域;Performing feature detection of the chamber angle on the cross-sectional image of the anterior segment to obtain a first chamber angle region and a second chamber angle region;
基于所述第一房角区域和第二房角区域对所述眼前节横断面图像进行剪裁,得到第一房角特征区域图像和第二房角特征区域图像。The anterior segment cross-sectional image is clipped based on the first chamber angle region and the second chamber angle region to obtain a first chamber angle characteristic region image and a second chamber angle characteristic region image.
可选的,在基于所述第一房角区域和第二房角区域对所述眼前节横断面图像进行剪裁之前,还包括:Optionally, before clipping the anterior segment cross-sectional image based on the first chamber angle region and the second chamber angle region, the method further includes:
获取第一房角特征区域和第二房角特征区域对应的尺寸;Acquiring sizes corresponding to the first chamber angle characteristic area and the second chamber angle characteristic area;
将所述第一房角特征区域和第二房角特征区域的尺寸进行对比;Comparing the sizes of the first chamber angle characteristic region and the second chamber angle characteristic region;
根据对比结果,对尺寸小的房角特征区域进行调整,使所述第一房角特征区域和第二房角特征区域的尺寸一致。According to the comparison result, the small-sized chamber angle characteristic region is adjusted so that the sizes of the first chamber angle characteristic region and the second chamber angle characteristic region are consistent.
可选的,对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果,包括:Optionally, converting the image of the characteristic area of the chamber angle into a thermal map, and inputting the converted thermal image and the cross-sectional image of the anterior segment into a preset second classification network model to obtain a second classification result, include:
将所述房角特征区域图像进行高斯转化,生成高斯分布热力图;performing Gaussian transformation on the image of the chamber angle feature region to generate a Gaussian distribution heat map;
将所述高斯分布热力图和所述眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果。Input the Gaussian distribution heat map and the anterior segment cross-sectional image into the preset second classification network model to obtain the second classification result.
可选的,对所述第一分型结果和第二分型结果进行分析,得到所述眼前节横断面图像的分型结果,包括:Optionally, analyzing the first typing result and the second typing result to obtain the typing result of the anterior segment cross-sectional image, including:
对所述第一分型结果和第二分型结果进行加权对比分析,得到各个分型类别对应的概率值;Performing a weighted comparative analysis on the first typing result and the second typing result to obtain the probability values corresponding to each typing category;
将概率值最高的分型类别确定为所述眼前节横断面图像的分型结果。The typing category with the highest probability value is determined as the typing result of the anterior segment cross-sectional image.
本申请实施例还提供了一种原发性闭角型青光眼的房角关闭机制分型装置,包括:The embodiment of the present application also provides an angle-closure mechanism classification device for primary angle-closure glaucoma, including:
获取模块:用于获取待分型的眼前节横断面图像;Acquisition module: used to acquire cross-sectional images of the anterior segment to be classified;
检测模块:用于对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像;Detection module: used to perform feature detection of the room angle on the anterior segment cross-sectional image, and obtain an image of the room angle feature region;
第一分型模块:用于将所述房角特征区域图像输入预设的第一分型网络模型得到第一分型结果;The first classification module: for inputting the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result;
第二分型模块:用于对所述房角特征区域图像进行热力图的转化,并将转 化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果;The second classification module: used to convert the thermal map of the image of the characteristic region of the room angle, and input the converted thermal image and the cross-sectional image of the anterior segment into the preset second classification network model to obtain the second Typing results;
分析模块:用于对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像。An analysis module: used for performing a feature detection of the room angle on the cross-sectional image of the anterior segment to obtain an image of a room angle feature area.
可选的,所述第二分型模块,包括:Optionally, the second typing module includes:
转化模块:用于将所述房角特征区域图像进行高斯转化,生成高斯分布热力图;Transformation module: used to perform Gaussian transformation on the image of the room angle feature region to generate a Gaussian distribution heat map;
分型处理模块:用于将所述高斯分布热力图和所述眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果。Typing processing module: used to input the Gaussian distribution heat map and the anterior segment cross-sectional image into the preset second typing network model to obtain the second typing result.
本申请实施例还提供了一种电子设备,包括:The embodiment of the present application also provides an electronic device, including:
存储器和处理器,所述存储器和所述处理器之间互相通信连接,所述存储器中存储有计算机指令,所述处理器通过执行所述计算机指令,从而执行本申请实施例提供的原发性闭角型青光眼的房角关闭机制分型方法。A memory and a processor, the memory and the processor are connected in communication with each other, computer instructions are stored in the memory, and the processor executes the computer instructions to execute the originality provided by the embodiments of the present application. Classification of angle-closure mechanism in angle-closure glaucoma.
本申请实施例还提供了一种计算机可读存储介质,所述计算机可读存储介质存储计算机指令,所述计算机指令用于使所述计算机执行本申请实施例提供的原发性闭角型青光眼的房角关闭机制分型方法。The embodiment of the present application also provides a computer-readable storage medium, the computer-readable storage medium stores computer instructions, and the computer instructions are used to make the computer execute the primary angle-closure glaucoma method provided in the embodiment of the present application. A classification method for the angle closure mechanism.
本申请技术方案,具有如下优点:The technical solution of the present application has the following advantages:
本申请提供了一种原发性闭角型青光眼的房角关闭机制分型方法,通过获取待分型的眼前节横断面图像;对眼前节横断面图像进行房角的特征检测,得到房角特征区域图像;将房角特征区域图像输入预设的第一分型网络模型得到第一分型结果;对房角特征区域图像进行热力图的转化,并将转化后的热力图像与眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果;对第一分型结果和第二分型结果进行分析,得到眼前节横断面图像的分型结果。本申请实现了基于人工智能的快速、客观的闭青房角关闭机制分型,将眼前节横 断面图像通过两种不同的方式进行处理得到两种分型结果,再通过对两种分型结果进行分析得到最终结果,两种分型结果相较于传统的人工分型方式,都更加的客观和准确,有效提高了分型的精度,为医生后续的诊断带来便利,同时通过分型网络模型可以较快的对图像进行分型处理,提高了分型的效率。This application provides a method for typing the angle closure mechanism of primary angle-closure glaucoma, by obtaining the cross-sectional image of the anterior segment to be typed; performing a characteristic detection of the angle on the cross-sectional image of the anterior segment to obtain the angle Feature area image; input the image of the room angle feature area into the preset first classification network model to obtain the first classification result; convert the image of the room angle feature area into a thermal map, and transect the transformed thermal image with the anterior segment The surface image is input into the preset second classification network model to obtain the second classification result; the first classification result and the second classification result are analyzed to obtain the classification result of the anterior segment cross-sectional image. This application realizes the rapid and objective classification of closed angle closure mechanism based on artificial intelligence. The cross-sectional images of the anterior segment are processed in two different ways to obtain two classification results, and then through the two classification results Perform analysis to get the final result. Compared with the traditional manual typing method, the two typing results are more objective and accurate, which effectively improves the typing accuracy and brings convenience to the doctor's subsequent diagnosis. At the same time, through the typing network The model can quickly classify images and improve the efficiency of classification.
附图说明Description of drawings
为了更清楚地说明本申请具体实施方式或现有技术中的技术方案,下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图是本申请的一些实施方式,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the following will briefly introduce the accompanying drawings that need to be used in the description of the specific embodiments or prior art. Obviously, the accompanying drawings in the following description The figures show some implementations of the present application, and those skilled in the art can obtain other figures based on these figures without any creative effort.
图1为本申请实施例中的原发性闭角型青光眼的房角关闭机制分型方法的流程图;Fig. 1 is the flow chart of the angle closure mechanism classification method of primary angle-closure glaucoma in the embodiment of the present application;
图2为根据本申请实施例中得到房角特征区域图像的流程图;Fig. 2 is a flow chart of obtaining an image of a room angle feature region according to an embodiment of the present application;
图3为根据本申请实施例中对眼前节横断面图像进行房角的特征检测的流程图;Fig. 3 is a flow chart of feature detection of room angle on an anterior segment cross-sectional image according to an embodiment of the present application;
图4为根据本申请实施例中对房角特征区域图像进行调整的流程图;Fig. 4 is a flow chart of adjusting the image of the room angle feature region according to the embodiment of the present application;
图5为根据本申请实施例中得到第二分型结果的流程图;Fig. 5 is a flow chart of obtaining the second typing result according to the embodiment of the present application;
图6为根据本申请实施例中对分型结果进行加权对比分析的流程图;FIG. 6 is a flow chart of weighted comparative analysis of typing results according to the embodiment of the present application;
图7为本申请实施例中的原发性闭角型青光眼的房角关闭机制分型装置的结构示意图;FIG. 7 is a schematic structural diagram of an angle-closure mechanism typing device for primary angle-closure glaucoma in an embodiment of the present application;
图8为本申请实施例中第二分型模块的结构示意图;Fig. 8 is a schematic structural diagram of the second typing module in the embodiment of the present application;
图9为本申请实施例中的电子设备的结构示意图。FIG. 9 is a schematic structural diagram of an electronic device in an embodiment of the present application.
具体实施方式Detailed ways
为使本申请实施例的目的、技术方案和优点更加清楚,下面将结合本申请 实施例中的附图,对本申请实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本申请一部分实施例,而不是全部的实施例。基于本申请中的实施例,本领域技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本申请保护的范围。In order to make the purposes, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments It is a part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without making creative efforts belong to the scope of protection of this application.
根据本申请实施例,提供了一种原发性闭角型青光眼的房角关闭机制分型方法实施例,需要说明的是,在附图的流程图示出的步骤可以在诸如一组计算机可执行指令的计算机系统中执行,并且,虽然在流程图中示出了逻辑顺序,但是在某些情况下,可以以不同于此处的顺序执行所示出或描述的步骤。According to the embodiment of the present application, an embodiment of a method for typing the angle closure mechanism of primary angle-closure glaucoma is provided. Instructions are executed in a computer system and, although a logical order is shown in the flowcharts, in some cases the steps shown or described may be performed in an order different from that shown or described herein.
在本实施例中提供了一种原发性闭角型青光眼的房角关闭机制分型方法,如图1所示,该原发性闭角型青光眼的房角关闭机制分型方法包括如下步骤:In this embodiment, a method for typing the angle closure mechanism of primary angle-closure glaucoma is provided, as shown in Figure 1, the method for typing the angle closure mechanism of primary angle-closure glaucoma includes the following steps :
步骤S1:获取待分型的眼前节横断面图像。具体的,待分型的眼前节横断面图像为眼前节横断面的光学相干断层扫描(optical coherence tomography,OCT)图像,前节OCT检查采用不可见光能够得到眼前节清晰的横断面图像,并可对眼前房和房角进行非接触性、定性/定量的评估和测量。同时,前节OCT避免了对房角形态和瞳孔直径的影响,并且不会压迫眼球,使存在的房角关闭不会因为检查操作的干扰而被漏诊。Step S1: Obtain cross-sectional images of the anterior segment to be classified. Specifically, the cross-sectional image of the anterior segment to be classified is an optical coherence tomography (OCT) image of the cross-section of the anterior segment. Anterior segment OCT examination using invisible light can obtain a clear cross-sectional image of the anterior segment, and can Non-contact, qualitative/quantitative assessment and measurement of the anterior chamber and angle. At the same time, the anterior segment OCT avoids the impact on the angle shape and pupil diameter, and does not compress the eyeball, so that the existing angle closure will not be missed due to the interference of the inspection operation.
步骤S2:对眼前节横断面图像进行房角的特征检测,得到房角特征区域图像。具体的,通过Roi检测网络对眼前节横断面图像进行房角的特征检测,获得重点关注的房角附近图像并对其进行框选,得到房角特征区域图像,此方式获取的房角特征区域较为精确,为后续的分型过程提供保障。Step S2: The feature detection of the room angle is performed on the cross-sectional image of the anterior segment to obtain the image of the room angle feature area. Specifically, the Roi detection network is used to detect the feature of the anterior segment cross-sectional image of the room angle, obtain the image near the room angle that is focused on and frame it, and obtain the image of the room angle feature area. The room angle feature area obtained in this way It is more accurate and provides guarantee for the subsequent typing process.
步骤S3:将房角特征区域图像输入预设的第一分型网络模型得到第一分型结果。具体的,第一分型网络模型为卷积神经网络,此过程中的房角特征区域图像为带有全局信息并加强了局部信息的特征图,通过将房角特征区域图像输入预设的第一分型网络模型,可以得到相较于传统人工判断更加客观的第一分型结果。Step S3: Input the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result. Specifically, the first classification network model is a convolutional neural network. The image of the room angle feature region in this process is a feature map with global information and enhanced local information. By inputting the image of the room angle feature region into the preset first The one-category network model can obtain a more objective first-category result than traditional manual judgment.
步骤S4:对房角特征区域图像进行热力图的转化,并将转化后的热力图像与眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果。具体的,第二分型网络模型深度学习网络模型,是通过大量的病例图像及诊断结果进行人工智能训练后得到的,通过将热力转化获得高斯分布热力图,将高斯分布热力图和眼前节横断面图像一起输入深度学习网络模型,使深度学习网络模型分析图片的全局信息的同时,重点关注热力图像的高斯圆区域,得到第二分型结果。Step S4: Transform the image of the characteristic area of the chamber angle into a thermal map, and input the converted thermal image and the cross-sectional image of the anterior segment into the preset second classification network model to obtain the second classification result. Specifically, the deep learning network model of the second classification network model is obtained after artificial intelligence training through a large number of case images and diagnosis results. The Gaussian distribution heat map is obtained by converting the heat force, and the Gaussian distribution heat map and the anterior segment are transected. Input the deep learning network model together with the surface image, so that the deep learning network model can analyze the global information of the picture and focus on the Gaussian circle area of the thermal image to obtain the second classification result.
步骤S5:对第一分型结果和第二分型结果进行分析,得到眼前节横断面图像的分型结果。Step S5: Analyzing the first typing result and the second typing result to obtain the typing result of the cross-sectional image of the anterior segment.
通过上述步骤S1至步骤S5,本申请实施例提供的原发性闭角型青光眼的房角关闭机制分型方法,本申请实现了基于人工智能的快速、客观的闭青房角关闭机制分型,将眼前节横断面图像通过两种不同的方式进行处理得到两种分型结果,再通过对两种分型结果进行分析得到最终结果,两种分型结果相较于传统的人工分型方式,都更加的客观和准确,有效提高了分型的精度,为医生后续的诊断带来便利;同时通过分型网络模型可以较快的对图像进行分型处理,提高了分型的效率。Through the above steps S1 to S5, the method for typing the angle closure mechanism of primary angle-closure glaucoma provided by the embodiment of the present application, the application realizes the rapid and objective classification of the angle closure mechanism based on artificial intelligence , the cross-sectional image of the anterior segment is processed in two different ways to obtain two typing results, and then the final result is obtained by analyzing the two typing results. Compared with the traditional manual typing method, the two typing results , are more objective and accurate, effectively improving the accuracy of typing, and bringing convenience to doctors' follow-up diagnosis; at the same time, through the typing network model, images can be typed quickly, improving the efficiency of typing.
具体地,在一实施例中,上述的步骤S2,如图2所示,具体包括如下步骤:Specifically, in one embodiment, the above step S2, as shown in FIG. 2 , specifically includes the following steps:
步骤S21:对眼前节横断面图像进行房角的特征检测,得到第一房角特征区域图像和第二房角特征区域图像。具体的,在眼前节横断面图像中,房角特征区域分为左右两侧,需要对特征区域进行分别提取。Step S21: Perform feature detection of the room angle on the cross-sectional image of the anterior segment to obtain a first room angle feature area image and a second room angle feature area image. Specifically, in the cross-sectional image of the anterior segment, the characteristic regions of the chamber angle are divided into left and right sides, and the characteristic regions need to be extracted separately.
步骤S22:将第一房角特征区域图像和第二房角特征区域图像进行组合,得到房角特征区域图像。Step S22: combining the first image of the characteristic region of the chamber angle and the image of the second characteristic region of the chamber angle to obtain the image of the characteristic region of the chamber angle.
具体地,在一实施例中,上述的步骤S21,如图3所示,具体包括如下步骤:Specifically, in one embodiment, the above step S21, as shown in FIG. 3 , specifically includes the following steps:
步骤S211:对眼前节横断面图像进行房角的特征检测,得到第一房角区域 和第二房角区域。具体的,在进行房角特征区域的提取前,需要确定房角区域的位置,通过ROI的目标检测,可以较为准确的获取将放区域的位置,并对特征区域进行框选。Step S211: Perform feature detection of the chamber angle on the cross-sectional image of the anterior segment to obtain the first chamber angle region and the second chamber angle region. Specifically, before extracting the room angle characteristic area, the position of the room angle area needs to be determined. Through the target detection of the ROI, the position of the area to be placed can be obtained more accurately, and the feature area is framed.
步骤S212:基于第一房角区域和第二房角区域对眼前节横断面图像进行剪裁,得到第一房角特征区域图像和第二房角特征区域图像。具体的,剪裁后得到的是带有全局信息并加强了局部信息的房角特征区域图像。Step S212: Clipping the anterior segment cross-sectional image based on the first chamber angle region and the second chamber angle region to obtain the first chamber angle characteristic region image and the second chamber angle characteristic region image. Specifically, what is obtained after clipping is an image of a room angle feature region with global information and enhanced local information.
具体地,在一实施例中,在进行上述的步骤S212之前,如图4所示,具体包括如下步骤:Specifically, in one embodiment, before performing the above-mentioned step S212, as shown in FIG. 4 , the following steps are specifically included:
步骤S2101:获取第一房角特征区域和第二房角特征区域对应的尺寸;Step S2101: Acquiring the corresponding sizes of the first chamber angle characteristic area and the second chamber angle characteristic area;
步骤S2102:将第一房角特征区域和第二房角特征区域的尺寸进行对比;Step S2102: Comparing the sizes of the first chamber angle characteristic area and the second chamber angle characteristic area;
步骤S2103:根据对比结果,对尺寸小的房角特征区域进行调整,使第一房角特征区域和第二房角特征区域的尺寸一致。Step S2103: According to the comparison result, adjust the small-sized chamber angle characteristic region, so that the sizes of the first chamber angle characteristic region and the second chamber angle characteristic region are the same.
具体的,由于在提取房角特征区域图像的过程中,左右两侧的第一房角特征区域图像和第二房角特征区域图像的大小可能不一致,需要对其进行调整。调整的过程可以通过ROI pooling进行调整,也可以通过其他方式进行调整使第一房角特征区域图像和第二房角特征区域图像的尺寸一致,在此不做具体限制。尺寸一致的房角特征区域图像为后续分型提供便利。Specifically, during the process of extracting the image of the characteristic region of the chamber angle, the sizes of the first characteristic region image of the chamber angle and the image of the second characteristic region of the chamber angle on the left and right sides may be inconsistent in size, and need to be adjusted. The adjustment process can be adjusted through ROI pooling, or adjusted in other ways to make the first chamber angle characteristic region image and the second chamber angle characteristic region image have the same size, and no specific limitation is set here. The image of the characteristic area of the chamber angle with consistent size facilitates the subsequent classification.
具体地,在一实施例中,上述的步骤S4,如图5所示,具体包括如下步骤:Specifically, in one embodiment, the above step S4, as shown in FIG. 5 , specifically includes the following steps:
步骤S41:将房角特征区域图像进行高斯转化,生成高斯分布热力图。具体的,通过高斯分布热力图体现重点关注部分的概率分布。Step S41: Gaussian transformation is performed on the image of the characteristic region of the room angle to generate a Gaussian distribution heat map. Specifically, the Gaussian distribution heat map reflects the probability distribution of the key attention parts.
步骤S42:将高斯分布热力图和眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果。具体的,第二分型网络模型深度学习网络模型,可用其他深度学习分类网络代替,包括且不限于:inceptionV4、seResnet等。是通过大量的病例图像及诊断结果进行人工智能训练后得到的,通过将高斯分 布热力图和眼前节横断面图像一起输入深度学习网络模型,使深度学习网络模型分析图片的全局信息的同时,重点关注热力图像的高斯圆区域,得到第二分型结果,使分型结果更加的客观准确。Step S42: Input the Gaussian distribution heat map and the cross-sectional image of the anterior segment into the preset second classification network model to obtain the second classification result. Specifically, the deep learning network model of the second classification network model can be replaced by other deep learning classification networks, including but not limited to: inceptionV4, seResnet, etc. It is obtained after artificial intelligence training through a large number of case images and diagnostic results. By inputting the Gaussian distribution heat map and the anterior segment cross-sectional image together into the deep learning network model, the deep learning network model can analyze the global information of the picture and at the same time focus on Focus on the Gaussian circle area of the thermal image to get the second classification result, which makes the classification result more objective and accurate.
具体地,在一实施例中,上述的步骤S5,如图6所示,具体包括如下步骤:Specifically, in one embodiment, the above step S5, as shown in FIG. 6, specifically includes the following steps:
步骤S51:对第一分型结果和第二分型结果进行加权对比分析,得到各个分型类别对应的概率值。具体的,在进行加权对比分析时,可以选择logit加权、softmax加权、01加权等。Step S51: Perform weighted comparative analysis on the first typing result and the second typing result to obtain the probability values corresponding to each typing category. Specifically, when performing weighted comparative analysis, logit weighting, softmax weighting, 01 weighting, etc. can be selected.
步骤S52:将概率值最高的分型类别确定为眼前节横断面图像的分型结果。具体的,以softmax加权为例,以第一分型结果和第二分型结果的概率值作为判断依据,可以分析较为丰富的信息量,从而得到较为均衡的分型结果。Step S52: Determine the typing category with the highest probability value as the typing result of the anterior segment cross-sectional image. Specifically, taking softmax weighting as an example, using the probability values of the first typing result and the second typing result as the judgment basis, a richer amount of information can be analyzed to obtain a more balanced typing result.
本申请将眼前节横断面图像通过两种不同的方式进行处理得到两种分型结果,再通过对两种分型结果进行分析得到最终结果,两种分型结果相较于传统的人工分型方式,都更加的客观和准确,有效提高了分型的精度,有效提高了分型的精度,为医生后续的诊断带来便利,同时通过分型网络模型可以较快的对图像进行分型处理,提高了分型的效率。In this application, the cross-sectional images of the anterior segment are processed in two different ways to obtain two typing results, and then the final results are obtained by analyzing the two typing results. Compared with the traditional manual typing, the two typing results The method is more objective and accurate, which effectively improves the accuracy of typing, effectively improves the accuracy of typing, and brings convenience to doctors' follow-up diagnosis. At the same time, images can be typed quickly through the typing network model. , improving the typing efficiency.
在本实施例中还提供了一种原发性闭角型青光眼的房角关闭机制分型装置,该装置用于实现上述实施例及优选实施方式,已经进行过说明的不再赘述。如以下所使用的,术语“模块”可以实现预定功能的软件和/或硬件的组合。尽管以下实施例所描述的装置较佳地以软件来实现,但是硬件,或者软件和硬件的组合的实现也是可能并被构想的。This embodiment also provides an angle-closure mechanism classification device for primary angle-closure glaucoma, which is used to implement the above-mentioned embodiments and preferred implementation modes, and those that have already been described will not be repeated. As used below, the term "module" may be a combination of software and/or hardware that realizes a predetermined function. Although the devices described in the following embodiments are preferably implemented in software, implementations in hardware, or a combination of software and hardware are also possible and contemplated.
本实施例提供一种原发性闭角型青光眼的房角关闭机制分型装置,如图7所示,包括:The present embodiment provides an angle-closure mechanism typing device for primary angle-closure glaucoma, as shown in FIG. 7 , comprising:
获取模块101,用于获取待分型的眼前节横断面图像,详细内容参见上述方法实施例中步骤S1的相关描述,在此不再进行赘述。The acquiring module 101 is configured to acquire the cross-sectional image of the anterior segment to be typed. For details, refer to the relevant description of step S1 in the above method embodiment, which will not be repeated here.
检测模块102,用于对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像,详细内容参见上述方法实施例中步骤S2的相关描述,在此不再进行赘述。The detection module 102 is configured to detect the feature of the room angle on the cross-sectional image of the anterior segment to obtain the image of the feature area of the room angle. For details, refer to the relevant description of step S2 in the above method embodiment, and will not be repeated here.
第一分型模块103,用于将所述房角特征区域图像输入预设的第一分型网络模型得到第一分型结果,详细内容参见上述方法实施例中步骤S3的相关描述,在此不再进行赘述。The first classification module 103 is configured to input the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result. For details, refer to the relevant description of step S3 in the above method embodiment, here No further details will be given.
第二分型模块104,用于对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果,详细内容参见上述方法实施例中步骤S4的相关描述,在此不再进行赘述。The second typing module 104 is used to convert the thermal map of the image of the characteristic area of the room angle, and input the converted thermal image and the cross-sectional image of the anterior segment into the preset second typing network model to obtain the second classification network model. For the dichotomous results, refer to the relevant description of step S4 in the above method embodiment for details, and details are not repeated here.
分析模块105,对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像,详细内容参见上述方法实施例中步骤S5的相关描述,在此不再进行赘述。The analysis module 105 performs feature detection of the room angle on the anterior segment cross-sectional image to obtain an image of the room angle characteristic area. For details, refer to the relevant description of step S5 in the above method embodiment, and will not be repeated here.
具体地,在一实施例中,上述的第二分型模块104,如图8所示,具体包括:Specifically, in one embodiment, the above-mentioned second typing module 104, as shown in FIG. 8 , specifically includes:
转化模块1041:用于将房角特征区域图像进行高斯转化,生成高斯分布热力图,详细内容参见上述方法实施例中步骤S41的相关描述,在此不再进行赘述。Transformation module 1041: used to perform Gaussian transformation on the image of the characteristic region of the room angle to generate a heat map of Gaussian distribution. For details, refer to the relevant description of step S41 in the above method embodiment, which will not be repeated here.
分型处理模块1042:用于将高斯分布热力图和眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果,详细内容参见上述方法实施例中步骤S42的相关描述,在此不再进行赘述。Typing processing module 1042: used to input the Gaussian distribution heat map and the anterior segment cross-sectional image into the preset second typing network model to obtain the second typing result. For details, refer to the relevant description of step S42 in the above method embodiment , which will not be repeated here.
本实施例中的原发性闭角型青光眼的房角关闭机制分型装置是以功能单元的形式来呈现,这里的单元是指ASIC电路,执行一个或多个软件或固定程序的处理器和存储器,和/或其他可以提供上述功能的器件。The angle-closure mechanism classification device for primary angle-closure glaucoma in this embodiment is presented in the form of a functional unit, where the unit refers to an ASIC circuit, a processor that executes one or more software or fixed programs, and Memory, and/or other devices that can provide the above functions.
上述各个模块的更进一步的功能描述与上述对应实施例相同,在此不再赘述。Further functional descriptions of the above-mentioned modules are the same as those in the above-mentioned corresponding embodiments, and will not be repeated here.
根据本申请实施例还提供了一种电子设备,如图9所示,该电子设备可以包括处理器901和存储器902,其中处理器901和存储器902可以通过总线或者其他方式连接,图9中以通过总线连接为例。According to the embodiment of the present application, an electronic device is also provided. As shown in FIG. 9, the electronic device may include a processor 901 and a memory 902, wherein the processor 901 and the memory 902 may be connected through a bus or in other ways. In FIG. 9, the Take connection via bus as an example.
处理器901可以为中央处理器(Central Processing Unit,CPU)。处理器901还可以为其他通用处理器、数字信号处理器(Digital Signal Processor,DSP)、专用集成电路(Application Specific Integrated Circuit,ASIC)、现场可编程门阵列(Field-Programmable Gate Array,FPGA)或者其他可编程逻辑器件、分立门或者晶体管逻辑器件、分立硬件组件等芯片,或者上述各类芯片的组合。The processor 901 may be a central processing unit (Central Processing Unit, CPU). The processor 901 can also be other general-purpose processors, digital signal processors (Digital Signal Processor, DSP), application-specific integrated circuits (Application Specific Integrated Circuit, ASIC), field-programmable gate array (Field-Programmable Gate Array, FPGA) or Other chips such as programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, or combinations of the above-mentioned types of chips.
存储器902作为一种非暂态计算机可读存储介质,可用于存储非暂态软件程序、非暂态计算机可执行程序以及模块,如本申请方法实施例中的方法所对应的程序指令/模块。处理器901通过运行存储在存储器902中的非暂态软件程序、指令以及模块,从而执行处理器的各种功能应用以及数据处理,即实现上述方法实施例中的方法。As a non-transitory computer-readable storage medium, the memory 902 can be used to store non-transitory software programs, non-transitory computer-executable programs and modules, such as program instructions/modules corresponding to the methods in the method embodiments of the present application. The processor 901 executes various functional applications and data processing of the processor by running the non-transitory software programs, instructions and modules stored in the memory 902, that is, implements the methods in the above method embodiments.
存储器902可以包括存储程序区和存储数据区,其中,存储程序区可存储操作系统、至少一个功能所需要的应用程序;存储数据区可存储处理器901所创建的数据等。此外,存储器902可以包括高速随机存取存储器,还可以包括非暂态存储器,例如至少一个磁盘存储器件、闪存器件、或其他非暂态固态存储器件。在一些实施例中,存储器902可选包括相对于处理器901远程设置的存储器,这些远程存储器可以通过网络连接至处理器901。上述网络的实例包括但不限于互联网、企业内部网、局域网、移动通信网及其组合。The memory 902 may include a program storage area and a data storage area, wherein the program storage area may store an operating system and an application program required by at least one function; the data storage area may store data created by the processor 901 and the like. In addition, the memory 902 may include a high-speed random access memory, and may also include a non-transitory memory, such as at least one magnetic disk storage device, a flash memory device, or other non-transitory solid-state storage devices. In some embodiments, the storage 902 may optionally include storages that are remotely located relative to the processor 901, and these remote storages may be connected to the processor 901 through a network. Examples of the aforementioned networks include, but are not limited to, the Internet, intranets, local area networks, mobile communication networks, and combinations thereof.
一个或者多个模块存储在存储器902中,当被处理器901执行时,执行上述方法实施例中的方法。One or more modules are stored in the memory 902, and when executed by the processor 901, the methods in the foregoing method embodiments are executed.
上述电子设备具体细节可以对应参阅上述方法实施例中对应的相关描述和 效果进行理解,此处不再赘述。The specific details of the above-mentioned electronic device can be understood by correspondingly referring to the corresponding descriptions and effects in the above-mentioned method embodiments, and will not be repeated here.
本领域技术人员可以理解,实现上述实施例方法中的全部或部分流程,是可以通过计算机程序来指令相关的硬件来完成,的程序可存储于一计算机可读取存储介质中,该程序在执行时,可包括如上述各方法的实施例的流程。其中,存储介质可为磁碟、光盘、只读存储记忆体(Read-Only Memory,ROM)、随机存储记忆体(Random Access Memory,RAM)、快闪存储器(Flash Memory)、硬盘(Hard Disk Drive,缩写:HDD)或固态硬盘(Solid-State Drive,SSD)等;存储介质还可以包括上述种类的存储器的组合。Those skilled in the art can understand that all or part of the processes in the methods of the above-mentioned embodiments can be completed by instructing related hardware through computer programs, and the programs can be stored in a computer-readable storage medium. , may include the flow of the embodiments of the above-mentioned methods. Wherein, the storage medium can be a magnetic disk, an optical disk, a read-only memory (Read-Only Memory, ROM), a random access memory (Random Access Memory, RAM), a flash memory (Flash Memory), a hard disk (Hard Disk Drive) , abbreviation: HDD) or solid-state drive (Solid-State Drive, SSD), etc.; the storage medium may also include a combination of the above-mentioned types of memory.
虽然结合附图描述了本申请的实施例,但是本领域技术人员可以在不脱离本申请的精神和范围的情况下做出各种修改和变型,这样的修改和变型均落入由所附权利要求所限定的范围之内。Although the embodiment of the application has been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the application, and such modifications and variations all fall within the scope of the appended claims. within the bounds of the requirements.

Claims (10)

  1. 一种原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,包括:A method for typing the angle closure mechanism of primary angle-closure glaucoma, comprising:
    获取待分型的眼前节横断面图像;Obtain cross-sectional images of the anterior segment to be classified;
    对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像;Performing a feature detection of the room angle on the anterior segment cross-sectional image to obtain a room angle feature region image;
    将所述房角特征区域图像输入预设的第一分型网络模型得到第一分型结果;Inputting the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result;
    对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果;Transforming the image of the characteristic area of the chamber angle into a thermal map, and inputting the converted thermal image and the anterior segment cross-sectional image into a preset second classification network model to obtain a second classification result;
    对所述第一分型结果和第二分型结果进行分析,得到所述眼前节横断面图像的分型结果。The first typing result and the second typing result are analyzed to obtain the typing result of the anterior segment cross-sectional image.
  2. 根据权利要求1所述的原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,所述对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像,包括:The method for typing the angle closure mechanism of primary angle-closure glaucoma according to claim 1, wherein the feature detection of the angle is performed on the cross-sectional image of the anterior segment to obtain an image of the characteristic area of the angle ,include:
    对所述眼前节横断面图像进行房角的特征检测,得到第一房角特征区域图像和第二房角特征区域图像;Performing a feature detection of the room angle on the cross-sectional image of the anterior segment to obtain a first room angle feature area image and a second room angle feature area image;
    将所述第一房角特征区域图像和第二房角特征区域图像进行组合,得到房角特征区域图像。Combining the first image of the characteristic region of the chamber angle with the image of the second characteristic region of the chamber angle to obtain the image of the characteristic region of the chamber angle.
  3. 根据权利要求2所述的原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,所述对所述眼前节横断面图像进行房角的特征检测,得到第一房角特征区域图像和第二房角特征区域图像,包括:The method for typing the angle closure mechanism of primary angle-closure glaucoma according to claim 2, wherein the feature detection of the room angle is performed on the anterior segment cross-sectional image to obtain the first room angle feature Regional images and second angle characteristic regional images, including:
    对所述眼前节横断面图像进行房角的特征检测,得到第一房角区域和第二房角区域;Performing feature detection of the chamber angle on the cross-sectional image of the anterior segment to obtain a first chamber angle region and a second chamber angle region;
    基于所述第一房角区域和第二房角区域对所述眼前节横断面图像进行剪裁,得到第一房角特征区域图像和第二房角特征区域图像。The anterior segment cross-sectional image is clipped based on the first chamber angle region and the second chamber angle region to obtain a first chamber angle characteristic region image and a second chamber angle characteristic region image.
  4. 根据权利要求3所述的原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,在基于所述第一房角区域和第二房角区域对所述眼前节横断面图像进行剪裁之前,还包括:The angle-closure mechanism classification method for primary angle-closure glaucoma according to claim 3, wherein the anterior segment cross-sectional image is analyzed based on the first angle area and the second angle area Before clipping, also include:
    获取第一房角特征区域和第二房角特征区域对应的尺寸;Acquiring sizes corresponding to the first chamber angle characteristic area and the second chamber angle characteristic area;
    将所述第一房角特征区域和第二房角特征区域的尺寸进行对比;Comparing the sizes of the first chamber angle characteristic region and the second chamber angle characteristic region;
    根据对比结果,对尺寸小的房角特征区域进行调整,使所述第一房角特征区域和第二房角特征区域的尺寸一致。According to the comparison result, the small-sized chamber angle characteristic region is adjusted so that the sizes of the first chamber angle characteristic region and the second chamber angle characteristic region are consistent.
  5. 根据权利要求1所述的原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,所述对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果,包括:The method for typing the angle closure mechanism of primary angle-closure glaucoma according to claim 1, wherein the conversion of the thermal map of the image of the characteristic region of the room angle is performed, and the converted thermal image Input the preset second classification network model with the anterior segment cross-sectional image to obtain a second classification result, including:
    将所述房角特征区域图像进行高斯转化,生成高斯分布热力图;performing Gaussian transformation on the image of the chamber angle feature region to generate a Gaussian distribution heat map;
    将所述高斯分布热力图和所述眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果。Input the Gaussian distribution heat map and the anterior segment cross-sectional image into the preset second classification network model to obtain the second classification result.
  6. 根据权利要求1所述的原发性闭角型青光眼的房角关闭机制分型方法,其特征在于,所述对所述第一分型结果和第二分型结果进行分析,得到所述眼前节横断面图像的分型结果,包括:The angle-closure mechanism typing method for primary angle-closure glaucoma according to claim 1, wherein the first typing result and the second typing result are analyzed to obtain the The classification results of section cross-sectional images, including:
    对所述第一分型结果和第二分型结果进行加权对比分析,得到各个分型类别对应的概率值;Performing a weighted comparative analysis on the first typing result and the second typing result to obtain the probability values corresponding to each typing category;
    将概率值最高的分型类别确定为所述眼前节横断面图像的分型结果。The typing category with the highest probability value is determined as the typing result of the anterior segment cross-sectional image.
  7. 一种原发性闭角型青光眼的房角关闭机制分型装置,其特征在于,包括:An angle-closure mechanism classification device for primary angle-closure glaucoma, characterized in that it includes:
    获取模块:用于获取待分型的眼前节横断面图像;Acquisition module: used to acquire cross-sectional images of the anterior segment to be classified;
    检测模块:用于对所述眼前节横断面图像进行房角的特征检测,得到房角特征区域图像;Detection module: used to perform feature detection of the room angle on the anterior segment cross-sectional image, and obtain an image of the room angle feature region;
    第一分型模块:用于将所述房角特征区域图像输入预设的第一分型网络模型得到第一分型结果;The first classification module: for inputting the image of the characteristic area of the chamber angle into the preset first classification network model to obtain the first classification result;
    第二分型模块:用于对所述房角特征区域图像进行热力图的转化,并将转化后的热力图像与所述眼前节横断面图像输入预设的第二分型网络模型得到第二分型结果;The second classification module: used to convert the thermal map of the image of the characteristic region of the room angle, and input the converted thermal image and the cross-sectional image of the anterior segment into the preset second classification network model to obtain the second Typing result;
    分析模块:用于对所述第一分型结果和第二分型结果进行分析,得到所述眼前节横断面图像的分型结果。Analysis module: used to analyze the first typing result and the second typing result to obtain the typing result of the anterior segment cross-sectional image.
  8. 根据权利要求7所述的原发性闭角型青光眼的房角关闭机制分型装置,其特征在于,所述第二分型模块,包括:The angle-closure mechanism typing device for primary angle-closure glaucoma according to claim 7, wherein the second typing module includes:
    转化模块:用于将所述房角特征区域图像进行高斯转化,生成高斯分布热力图;Transformation module: used to perform Gaussian transformation on the image of the room angle feature region to generate a Gaussian distribution heat map;
    分型处理模块:用于将所述高斯分布热力图和所述眼前节横断面图像输入预设的第二分型网络模型,得到第二分型结果。Typing processing module: used to input the Gaussian distribution heat map and the anterior segment cross-sectional image into the preset second typing network model to obtain the second typing result.
  9. 一种电子设备,其特征在于,包括:An electronic device, characterized in that it comprises:
    存储器和处理器,所述存储器和所述处理器之间互相通信连接,所述存储器中存储有计算机指令,所述处理器通过执行所述计算机指令,从而执行权利要求1至7中任一项所述的原发性闭角型青光眼的房角关闭机制分型方法。A memory and a processor, the memory and the processor are connected in communication with each other, computer instructions are stored in the memory, and the processor performs any one of claims 1 to 7 by executing the computer instructions The method for typing the angle closure mechanism of primary angle-closure glaucoma.
  10. 一种计算机可读存储介质,其特征在于,所述计算机可读存储介质存储有计算机指令,所述计算机指令用于使所述计算机执行权利要求1至7中任一项所述的原发性闭角型青光眼的房角关闭机制分型方法。A computer-readable storage medium, characterized in that the computer-readable storage medium stores computer instructions, and the computer instructions are used to make the computer perform the original invention described in any one of claims 1 to 7. Classification of angle-closure mechanism in angle-closure glaucoma.
PCT/CN2021/131258 2021-11-17 2021-11-17 Method for typing chamber angle closure mechanism of primary angle closure glaucoma WO2023087183A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2021/131258 WO2023087183A1 (en) 2021-11-17 2021-11-17 Method for typing chamber angle closure mechanism of primary angle closure glaucoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2021/131258 WO2023087183A1 (en) 2021-11-17 2021-11-17 Method for typing chamber angle closure mechanism of primary angle closure glaucoma

Publications (1)

Publication Number Publication Date
WO2023087183A1 true WO2023087183A1 (en) 2023-05-25

Family

ID=86396179

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2021/131258 WO2023087183A1 (en) 2021-11-17 2021-11-17 Method for typing chamber angle closure mechanism of primary angle closure glaucoma

Country Status (1)

Country Link
WO (1) WO2023087183A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150161785A1 (en) * 2012-08-02 2015-06-11 Singapore Health Services Pte Ltd Methods and systems for characterizing angle closure glaucoma for risk assessment or screening
WO2015166550A1 (en) * 2014-04-30 2015-11-05 株式会社クリュートメディカルシステムズ Ophthalmologic observation system
CN110310254A (en) * 2019-05-17 2019-10-08 广东技术师范大学 A kind of room angle image automatic grading method based on deep learning
US20200305706A1 (en) * 2017-12-11 2020-10-01 Universitat Politecnica De Catalunya Image processing method for glaucoma detection and computer program products thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150161785A1 (en) * 2012-08-02 2015-06-11 Singapore Health Services Pte Ltd Methods and systems for characterizing angle closure glaucoma for risk assessment or screening
WO2015166550A1 (en) * 2014-04-30 2015-11-05 株式会社クリュートメディカルシステムズ Ophthalmologic observation system
US20200305706A1 (en) * 2017-12-11 2020-10-01 Universitat Politecnica De Catalunya Image processing method for glaucoma detection and computer program products thereof
CN110310254A (en) * 2019-05-17 2019-10-08 广东技术师范大学 A kind of room angle image automatic grading method based on deep learning

Similar Documents

Publication Publication Date Title
US11295178B2 (en) Image classification method, server, and computer-readable storage medium
US11361192B2 (en) Image classification method, computer device, and computer-readable storage medium
KR102058884B1 (en) Method of analyzing iris image for diagnosing dementia in artificial intelligence
Fu et al. Angle-closure detection in anterior segment OCT based on multilevel deep network
US20190191988A1 (en) Screening method for automated detection of vision-degenerative diseases from color fundus images
WO2020133636A1 (en) Method and system for intelligent envelope detection and warning in prostate surgery
Nahiduzzaman et al. Hybrid CNN-SVD based prominent feature extraction and selection for grading diabetic retinopathy using extreme learning machine algorithm
Wu et al. U-GAN: Generative adversarial networks with U-Net for retinal vessel segmentation
CN111862009B (en) Classifying method of fundus OCT (optical coherence tomography) images and computer readable storage medium
Fan et al. Principal component analysis based cataract grading and classification
Jian et al. Triple-DRNet: A triple-cascade convolution neural network for diabetic retinopathy grading using fundus images
CN113012163A (en) Retina blood vessel segmentation method, equipment and storage medium based on multi-scale attention network
CN113782184A (en) Cerebral apoplexy auxiliary evaluation system based on facial key point and feature pre-learning
Yang et al. RADCU-Net: Residual attention and dual-supervision cascaded U-Net for retinal blood vessel segmentation
CN114332910A (en) Human body part segmentation method for similar feature calculation of far infrared image
Song et al. Semi-supervised learning based on cataract classification and grading
Miao et al. Classification of Diabetic Retinopathy Based on Multiscale Hybrid Attention Mechanism and Residual Algorithm
WO2023087183A1 (en) Method for typing chamber angle closure mechanism of primary angle closure glaucoma
WO2024087359A1 (en) Lesion detection method and apparatus for endoscope, and electronic device and storage medium
CN114038051B (en) Atrial angle closure mechanism typing method for primary angle closure glaucoma
Santos et al. Deep neural network model based on one-stage detector for identifying fundus lesions
Cui et al. Spatial multi-scale attention U-improved network for blood vessel segmentation
Santos et al. A new method based on deep learning to detect lesions in retinal images using YOLOv5
Li et al. A Deep-Learning-Enabled Monitoring System for Ocular Redness Assessment
Ramesh et al. Colon cancer detection using YOLOv5 architecture

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21964346

Country of ref document: EP

Kind code of ref document: A1