WO2023079570A1 - System and method for corneal 3d tomography of cornea - Google Patents

System and method for corneal 3d tomography of cornea Download PDF

Info

Publication number
WO2023079570A1
WO2023079570A1 PCT/IN2022/050947 IN2022050947W WO2023079570A1 WO 2023079570 A1 WO2023079570 A1 WO 2023079570A1 IN 2022050947 W IN2022050947 W IN 2022050947W WO 2023079570 A1 WO2023079570 A1 WO 2023079570A1
Authority
WO
WIPO (PCT)
Prior art keywords
eye
image
images
microprocessor unit
cornea
Prior art date
Application number
PCT/IN2022/050947
Other languages
French (fr)
Inventor
Narendra Singh Verma
Sanjay Garg
Original Assignee
Narendra Singh Verma
Sanjay Garg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Narendra Singh Verma, Sanjay Garg filed Critical Narendra Singh Verma
Publication of WO2023079570A1 publication Critical patent/WO2023079570A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/107—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining the shape or measuring the curvature of the cornea

Definitions

  • the present invention relates to a system and method for comeal tomography and 3D modeling of cornea in a human eye.
  • Devices available for measuring eye parameters include topographers, tomographers, keratometers, aberrometer, optical biometer and the like. These are either placcido based, wavefront based, Hartmann Shack principle based, ray tracing based, OCT based or Scheimpflug based devices. Mainly these instmments require complex systems and hence may have multiple possibilities of failure. Also they require learning curve to understand and interpret the system.
  • an US Patent 7976163B2 discloses system for measuring comeal topography of an eye.
  • the system includes a group of first light sources arranged around a central axis, the group being separated from the axis by a radial distance defining an aperture in the group; a plurality of second light sources; a detector array; and an optical system adapted to provide light from the second light sources through the aperture to a cornea of an eye, and to provide images of the first light sources and images of the second light sources from the cornea, through the aperture, to the detector array.
  • the optical system includes an optical element having a focal length, f.
  • the second light sources are disposed to be in an optical path approximately one focal length, f, away from the optical element.
  • Another European Patent EP0395831 discloses a three-dimensional contour measuring apparatus with first light beams directed onto the surface being measured. Reflections from the surface are received by a photo-detecting device for generating electrical output signals which are processed to determine the radius of curvature of the surface being measured. A higher spatial resolution can be achieved without changing the spacing of the array of light points.
  • An object of the present invention is to measure total comeal power its axis and provides 3D modeling of cornea in the eye which is useful in different surgical and non-surgical procedures.
  • Yet another object of the present invention is provide a novel, easy to use, reliable, non-cumbersome, examiner and examinee friendly system to measure total comeal power with its axis, and provide 3D modeling of cornea in the eye.
  • Figure 1 show a schematic drawing of a system used to measure total corneal power its axis and 3D modeling of cornea in eye.
  • Figure 2 shows a schematic representation of a workflow chart used for measurement of total comeal power its axis and 3D modeling of cornea in eye.
  • Figure 3 shows reflection of LED lights by anterior and posterior comeal surfaces
  • Figure 4 shows a photographic device of the system 1, in accordance with the present invention.
  • the present invention provides a system and method for comeal 3D tomography of an eye.
  • the system comprises arrangement of devices that can capture the image/video of eye, store, and process, calculate and display measurements including total comeal power with its axis and 3D modeling of cornea in eye.
  • the system of the present invention provides an economical, easy to use and easy to interpret system for these measurements.
  • the system can also be used in demonstration and education of patient/examinee about their eye condition.
  • the system (100) comprises an illuminating octagon shaped panel (102), a photographic device (103) for capturing the image of eye, coupled with microprocessor unit which is a single board computer as server (104) for processing an image of the eye and connected to a input device (107) or client devices (105), and a printing device (108), communication by wired or without wired network (106) .
  • the octagon shaped illuminating panel (102) includes multicolored LED’s configured in nearly circular pattern.
  • the photographic device (103) comprises at least one image capturing device configured in the center of the octagon shaped panel .
  • the one image capturing device (103) is a camera having motorised lens system which provides multiple focal length facility for capturing multiple images/videos of the eye between 5-30 cm range.
  • the octagon shaped panel (102) includes at least 600-1200 LED lights.
  • the each panel (102) of the octagon shaped illuminating system comprises at least 75 LEDs as shown in figure 4.
  • the advantage of having at least 600-1200 LEDs is that they can measure 600- 1200 points of the cornea at a single time. These 600 -1200 data points of central part of the cornea is useful for better comparison of the different parts of the cornea.
  • the system (100) further comprises a microprocessor unit which is a single board computer as server (104) coupled operatively to the photographic device (103), the microprocessor unit (104) is configured to control the image capturing device, the LEDS, and processing the images/videos to create 3D model of the cornea based on the images/video received.
  • the photographic device (103) captures multiple images/videos of the eye from various distance and provides them to the microprocessor unit (104) for making a 3D image of the eye and sends it for displaying, printing and data sharing.
  • the photographic device (103) is capable of being operated by an examiner/ophthalmologist to capture an image of an eye (101) of an examinee/patient. The captured images of the eye are then saved as an electric signal and shared to microprocessor unit (104).
  • microprocessor unit is a single board computer as server (104) is communicated by wired/wireless network(106) with an input device (107) which includes a monitor display and keyboard / mouse acts as signal input means for the microprocessor unit (104) or by an external client device(105) like laptop, pc, mobile, tablet etc.
  • client devices (105) or input device (107) are operatively controlled by the microprocessor unit (104) and display image/video data transmitted from the microprocessor unit (104).
  • the printing device (108) is operatively controlled by the microprocessor unit (104) and provides output calculation results and pictures.
  • FIG 2 there is shown a flowchart of a method (200) for measurement of total power with its axis of cornea of the eye and 3D comeal modeling (101) of the examinee.
  • the method (200) is described in conjunction with system (100).
  • the method (200) comprises capturing multiple image/videos of the eye of the examinee in a condition with different illumination and at different distances from eye through a photographic device (103).
  • the photographic device (103) captures multiple images/videos of the eye from minimum 5-30 cm distance of the eye.
  • the method (200) further comprises selecting the preferred images/video by the microprocessor unit (104).
  • the method (200) furthermore comprises calculating the total comeal power with its axis.
  • the comeal power is calculated by using images of the anterior surface and posterior surface of the cornea.
  • the combination of the anterior surface and posterior surface provides total comeal power with its axis and used in 3D modeling of cornea.
  • the 3D modeling of the cornea of the eye is based on calculating comeal axis of the anterior surface of the cornea and posterior surface of the cornea to get final comeal axis.
  • the microprocessor unit (104) prepare 3D modeling of the anterior surface and 3D modeling of the posterior surface to get 3D model of the cornea.
  • the microprocessor unit (104) is configured to process the information and presents as a colored topographic map in a hill and valley pattern and stored in the storage device.
  • each LED light of the light source produces two images on cornea, one brighter (109) from anterior surface of the cornea and other fainter (110) from posterior surface of cornea.
  • the images/videos of the eye is captured between 5-30 cm distance from the eye to get better quality of image by the camera system operating at multiple focal length and to cover more are of cornea by the photographic device(103).
  • a computerized video keratoscopy along with computer based image processing system through Al and digital image pixel
  • the total power and axis of cornea is measured by measuring position of image by computer based image processing system.
  • the information from comeal image is automatically presented in colored comeal topography map in a hill and valley pattern and 3D comeal modeling.
  • the image can be stored and displayed on the display device and can be used by the examiner for operative procedures or for educating the examinee/patient about the suitability of their eye for multifocal toric lens, refractive procedures and other surgical procedures.
  • the system (100) processes the pre and post operation data of the eye and provides Al based algorithm which predict change in the comeal curvature due to different site and size of the incision.
  • the system (100) of the present invention provides a novel, easy to use, reliable, non-cumbersome, examiner and examinee friendly system to measure total comeal astigmatism with its axis and 3D comeal modeling.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

Disclosed is a system and method for corneal 3d tomography of an eye. The system comprises a photographic device for capturing an image of the eye. The photographic device comprises octagon shaped panel having multicolored addressable LED lights configured in nearly circular pattern and at least one image capturing device configured in the center of the octagon shaped panel. The system further comprise of microprocessor unit configured to process the images the eye received from the photographic device in 3 D form, control the camera and LEDs.

Description

SYSTEM AND METHOD FOR CORNEAL 3D TOMOGRAPHY OF CORNEA
Field of the invention:
The present invention relates to a system and method for comeal tomography and 3D modeling of cornea in a human eye.
Background of the invention
The comeal tomography and 3D modeling of cornea of particular eye is very important in many surgical and non-surgical procedures in eye. . To measure these parameters requires multiple complex systems which are relatively expensive and unaffordable for most patients/examinees
Devices available for measuring eye parameters include topographers, tomographers, keratometers, aberrometer, optical biometer and the like. These are either placcido based, wavefront based, Hartmann Shack principle based, ray tracing based, OCT based or Scheimpflug based devices. Mainly these instmments require complex systems and hence may have multiple possibilities of failure. Also they require learning curve to understand and interpret the system.
Specifically, an US Patent 7976163B2 discloses system for measuring comeal topography of an eye. The system includes a group of first light sources arranged around a central axis, the group being separated from the axis by a radial distance defining an aperture in the group; a plurality of second light sources; a detector array; and an optical system adapted to provide light from the second light sources through the aperture to a cornea of an eye, and to provide images of the first light sources and images of the second light sources from the cornea, through the aperture, to the detector array. The optical system includes an optical element having a focal length, f. The second light sources are disposed to be in an optical path approximately one focal length, f, away from the optical element.
Another European Patent EP0395831 discloses a three-dimensional contour measuring apparatus with first light beams directed onto the surface being measured. Reflections from the surface are received by a photo-detecting device for generating electrical output signals which are processed to determine the radius of curvature of the surface being measured. A higher spatial resolution can be achieved without changing the spacing of the array of light points.
However, the result displayed by the available systems is not easily understandable by layman and in many cases even by an expert in the field. Hence ophthalmologist faces a difficulty while trying to educate/explain the patient/examinee about their eye condition. Also the cost required for setup and maintenance of these instruments is much high.
Accordingly, there exists a need to provide a system and method which determines total comeal power its axis and provide 3D tomography model of cornea which overcomes the drawbacks of the prior art.
Objects of the invention:
An object of the present invention is to measure total comeal power its axis and provides 3D modeling of cornea in the eye which is useful in different surgical and non-surgical procedures.
Yet another object of the present invention is provide a novel, easy to use, reliable, non-cumbersome, examiner and examinee friendly system to measure total comeal power with its axis, and provide 3D modeling of cornea in the eye.
Brief description of drawings Figure 1 show a schematic drawing of a system used to measure total corneal power its axis and 3D modeling of cornea in eye.
Figure 2 shows a schematic representation of a workflow chart used for measurement of total comeal power its axis and 3D modeling of cornea in eye.
Figure 3 shows reflection of LED lights by anterior and posterior comeal surfaces; and
Figure 4 shows a photographic device of the system 1, in accordance with the present invention.
Detailed description of the embodiments:
The foregoing objects of the present invention are accomplished and the problems and shortcomings associated with the prior art, techniques and approaches are overcome by the present invention as described below in the preferred embodiments.
The present invention provides a system and method for comeal 3D tomography of an eye. The system comprises arrangement of devices that can capture the image/video of eye, store, and process, calculate and display measurements including total comeal power with its axis and 3D modeling of cornea in eye. The system of the present invention provides an economical, easy to use and easy to interpret system for these measurements. The system can also be used in demonstration and education of patient/examinee about their eye condition.
Referring now to figures 1 to 4, there is shown a system (100) for measuring total comeal power with its axis and 3D modeling, in accordance with the present invention. The system (100) comprises an illuminating octagon shaped panel (102), a photographic device (103) for capturing the image of eye, coupled with microprocessor unit which is a single board computer as server (104) for processing an image of the eye and connected to a input device (107) or client devices (105), and a printing device (108), communication by wired or without wired network (106) .
The octagon shaped illuminating panel (102) includes multicolored LED’s configured in nearly circular pattern. Further the photographic device (103) comprises at least one image capturing device configured in the center of the octagon shaped panel . In an embodiment, the one image capturing device (103) is a camera having motorised lens system which provides multiple focal length facility for capturing multiple images/videos of the eye between 5-30 cm range.
In an embodiment, the octagon shaped panel (102) includes at least 600-1200 LED lights. In another embodiment, the each panel (102) of the octagon shaped illuminating system comprises at least 75 LEDs as shown in figure 4.
The advantage of having at least 600-1200 LEDs is that they can measure 600- 1200 points of the cornea at a single time. These 600 -1200 data points of central part of the cornea is useful for better comparison of the different parts of the cornea.
The system (100) further comprises a microprocessor unit which is a single board computer as server (104) coupled operatively to the photographic device (103), the microprocessor unit (104) is configured to control the image capturing device, the LEDS, and processing the images/videos to create 3D model of the cornea based on the images/video received. Specifically, the photographic device (103) captures multiple images/videos of the eye from various distance and provides them to the microprocessor unit (104) for making a 3D image of the eye and sends it for displaying, printing and data sharing. The photographic device (103) is capable of being operated by an examiner/ophthalmologist to capture an image of an eye (101) of an examinee/patient. The captured images of the eye are then saved as an electric signal and shared to microprocessor unit (104).
In an embodiment, microprocessor unit is a single board computer as server (104) is communicated by wired/wireless network(106) with an input device (107) which includes a monitor display and keyboard / mouse acts as signal input means for the microprocessor unit (104) or by an external client device(105) like laptop, pc, mobile, tablet etc.
Further, the client devices (105) or input device (107) are operatively controlled by the microprocessor unit (104) and display image/video data transmitted from the microprocessor unit (104).
Further, the printing device (108) is operatively controlled by the microprocessor unit (104) and provides output calculation results and pictures.
Referring now to figure 2, there is shown a flowchart of a method (200) for measurement of total power with its axis of cornea of the eye and 3D comeal modeling (101) of the examinee. The method (200) is described in conjunction with system (100).
The method (200) comprises capturing multiple image/videos of the eye of the examinee in a condition with different illumination and at different distances from eye through a photographic device (103). In preferred, the photographic device (103) captures multiple images/videos of the eye from minimum 5-30 cm distance of the eye. The method (200) further comprises selecting the preferred images/video by the microprocessor unit (104).
The method (200) furthermore comprises calculating the total comeal power with its axis. Specifically, the comeal power is calculated by using images of the anterior surface and posterior surface of the cornea. The combination of the anterior surface and posterior surface provides total comeal power with its axis and used in 3D modeling of cornea.
The 3D modeling of the cornea of the eye is based on calculating comeal axis of the anterior surface of the cornea and posterior surface of the cornea to get final comeal axis.
Similarly, based on the multiple images, videos the microprocessor unit (104) prepare 3D modeling of the anterior surface and 3D modeling of the posterior surface to get 3D model of the cornea.
Specifically, the microprocessor unit (104) is configured to process the information and presents as a colored topographic map in a hill and valley pattern and stored in the storage device.
More specifically, each LED light of the light source produces two images on cornea, one brighter (109) from anterior surface of the cornea and other fainter (110) from posterior surface of cornea. In an embodiment, the figure 3 and shows LED light source. In preferred embodiment, the images/videos of the eye is captured between 5-30 cm distance from the eye to get better quality of image by the camera system operating at multiple focal length and to cover more are of cornea by the photographic device(103). In another embodiment, for calculation of total comeal power with its axis of cornea, a computerized video keratoscopy along with computer based image processing system (through Al and digital image pixel) is used.
The total power and axis of cornea is measured by measuring position of image by computer based image processing system. The information from comeal image is automatically presented in colored comeal topography map in a hill and valley pattern and 3D comeal modeling.
The image can be stored and displayed on the display device and can be used by the examiner for operative procedures or for educating the examinee/patient about the suitability of their eye for multifocal toric lens, refractive procedures and other surgical procedures.
The system (100) processes the pre and post operation data of the eye and provides Al based algorithm which predict change in the comeal curvature due to different site and size of the incision.
Advantages of the invention
3. The system (100) of the present invention provides a novel, easy to use, reliable, non-cumbersome, examiner and examinee friendly system to measure total comeal astigmatism with its axis and 3D comeal modeling.
The foregoing descriptions of specific embodiments of the present invention have been presented for purposes of illustration and description. They are not intended to be exhaustive or to limit the present invention to the precise forms disclosed, and obviously many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the present invention and its practical application, to thereby enable others skilled in the art to best utilize the present invention and various embodiments with various modifications as are suited to the particular use contemplated. It is understood that various omission and substitutions of equivalents are contemplated as circumstance may suggest or render expedient, but such are intended to cover the application or implementation without departing from the scope of the present invention.

Claims

We claim
1. A system for corneal 3d tomography of an eye, the system comprising: a photographic device for capturing an image of the eye, the photographic device having,
• octagon shaped illuminating panel having multicolored addressable LED lights configured in nearly circular pattern,
• at least one image capturing device configured in the center of the octagon shaped panel; and a microprocessor unit is a single board computer as server is coupled operatively to the photographic device, the microprocessor unit is configured to control the image capturing device, the LEDS, and processing the images/videos to create 3 D model of the cornea based on the images/video received, wherein the image processing device captures multiple images/videos of the eye from various distance and provides them to the microprocessor unit for making a 3D image of the eye and sends it for displaying and printing.
2. The system as claimed in claim 1, wherein the image capturing device is a camera having motorised lens adjusting system with ability to take images with multiple focal length.
3. The system as claimed in claim 1, wherein the image capturing device captures the image of the eye from at least 5-30 cm from the eye.
4. The system as claimed in claim 1, wherein the octagon shaped panel includes at least 600-1200 addressable LED lights.
5. The system as claimed in claim 1, wherein each panel of the octagon shaped panel comprises microprocessor unit controlled addressable LEDs.
9
6. A method for comeal 3d tomography of an eye, the method comprising system comprising: capturing an image of the eye using a photographic device having a octagon shaped panel having multicolored LED lights configured in nearly circular pattern and at least one image capturing device configured in the center of the octagon shaped panel; and processing multiple images/ videos received from the photographic device by microprocessor unit, which creates 3D model of the cornea using multiple images/videos of the eye received from the photographic device.
7. The method as claimed in claim 6, wherein the image/video is captured using a camera having motorised lens adjusting system with ability to take images with multiple focal length.
8. The method as claimed in claim 6, wherein the image capturing device captures the image of the eye from at least 5-30 cm from the eye.
PCT/IN2022/050947 2021-11-04 2022-10-24 System and method for corneal 3d tomography of cornea WO2023079570A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202121050699 2021-11-04
IN202121050699 2021-11-04

Publications (1)

Publication Number Publication Date
WO2023079570A1 true WO2023079570A1 (en) 2023-05-11

Family

ID=86240735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2022/050947 WO2023079570A1 (en) 2021-11-04 2022-10-24 System and method for corneal 3d tomography of cornea

Country Status (1)

Country Link
WO (1) WO2023079570A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170273558A1 (en) * 2014-09-08 2017-09-28 Kabushiki Kaisha Topcon Ophthalmic imaging apparatus and ophthalmic information processing apparatus
US20210153735A1 (en) * 2017-07-27 2021-05-27 Topcon Corporation Ophthalmic system, ophthalmic information processing device, and ophthalmic diagnosing method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170273558A1 (en) * 2014-09-08 2017-09-28 Kabushiki Kaisha Topcon Ophthalmic imaging apparatus and ophthalmic information processing apparatus
US20210153735A1 (en) * 2017-07-27 2021-05-27 Topcon Corporation Ophthalmic system, ophthalmic information processing device, and ophthalmic diagnosing method

Similar Documents

Publication Publication Date Title
CN102596005B (en) Method and device for automatically measuring at least one refractive characteristic of both eyes of person
KR100992182B1 (en) Ophthalmic binocular wavefront measurement system
JP5448198B2 (en) Dual shine proof system for 3D eye analysis
JP2975306B2 (en) Apparatus and method for anterior segment imaging and slit lamp assembly
US10575725B2 (en) System and method for characterising eye-related systems
EP2268192B1 (en) Apparatus for corneal shape analysis and method for determining a corneal thickness
US9743832B2 (en) Apparatus for corneal shape analysis and method for determining a corneal thickness
JP2006341094A (en) Method for operating ophthalmological analysis system
CN106580244A (en) Portable infrared eccentric photorefraction system
US9572486B2 (en) Device and method for checking human vision
Gairola et al. SmartKC: smartphone-based corneal topographer for keratoconus detection
US20220076417A1 (en) Vision screening systems and methods
CN100463646C (en) Ophthalmic binocular wavefront measurement system
WO2023079570A1 (en) System and method for corneal 3d tomography of cornea
JP2020048857A (en) Eye measurement apparatus and method
CA3144153A1 (en) Dry eye mitigation for ocular aberrometry systems and methods
WO2022264154A1 (en) Method for assisting axis alignment of toric lens
US20210386287A1 (en) Determining refraction using eccentricity in a vision screening system
Miller A handheld open-field infant keratometer (an american ophthalmological society thesis)
EP3925519B1 (en) Vision screening systems and methods
JP3507186B2 (en) Corneal shape measuring device
Coghill et al. Stereo vision based optic nerve head 3D reconstruction using a slit lamp fitted with cameras: performance trial with an eye phantom
WO2023091660A1 (en) Vision screening systems and methods
JP2021137260A (en) Objective optometer
JP2021104282A (en) Ophthalmologic apparatus

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22889584

Country of ref document: EP

Kind code of ref document: A1