WO2023060629A1

WO2023060629A1 - Three-axis automatic objective table adaptable to various microscopes

Info

Publication number: WO2023060629A1
Application number: PCT/CN2021/124522
Authority: WO
Inventors: 李昕昱
Original assignee: 李昕昱
Priority date: 2021-10-12
Filing date: 2021-10-19
Publication date: 2023-04-20
Also published as: CN114035312A; WO2023060706A1

Abstract

A three-axis automatic objective table adaptable to various microscopes, the three-axis automatic objective table comprising a fixing plate (10), and a three-axis platform and a microscope (60), which are detachably arranged on the fixing plate (10). The three-axis platform comprises: an X-axis mechanism (20); a Y-axis mechanism (30), which is arranged on the X-axis mechanism (20); a Z-axis mechanism (40), which is arranged on the Y-axis mechanism (30); a first objective table (50), which is arranged on the Z-axis mechanism (40) and configured to place an examined object; and replaceable clamps (51, 52), which are arranged on the first objective table (50) and configured to adapt to various examined objects. The microscope (60) comprises a plurality of lenses (62), and a second objective table (61) of the microscope (60). The first objective table (50) on the three-axis platform can be used interchangeably with the second objective table (61) of the microscope (60), thereby realizing multiple purposes. The first objective table (50) can be adjusted in three directions, and cooperates with the lenses (62) of different magnifications of the microscope (60), a camera and the replaceable clamps (51, 52) to automatically observe, photograph, analyze, etc., the examined object on the first objective table (50), so as to adapt to microscopes of different brands and microscopes of different models under the same brand, which solves the problem of it being inconvenient to separately replace the objective table and the Z-axis mechanism for different microscopes, thereby improving the practicability.

Description

A three-axis automatic stage adaptable to various microscopes

technical field

The invention belongs to the technical field of automatic microscopes, in particular to a three-axis automatic stage that can be adapted to various microscopes.

Background technique

At present, there are two ways to move the stage of a common microscope and adjust the focus: manual and automatic, each of which has its own application scenarios. However, the application scenarios of each method will be limited (automatically adjusted microscopes cannot be adjusted manually, and manually adjusted microscopes cannot be automatically adjusted), and when refitting automatic adjustments of microscopes of different brands or different models of the same brand, many parts are required to adapt to different For different types of microscopes, especially the modification of focusing needs to change the original knob, and manually connect the motor to achieve automatic adjustment, which is easy to cause damage to the microscope. In addition, different microscopes are used in different scenarios, and the size and shape of the stage suitable for various objects to be inspected are different, which makes the cost of individual modification high, the process is cumbersome, and it is not easy to standardize, scale modification and production, and after modification The microscope can no longer be adjusted manually.

Contents of the invention

In view of this, the present invention provides a solution to the above-mentioned problems, and a three-axis automatic stage that can be adapted to a variety of microscopes, which includes a fixed plate, and three detachable mounted on the fixed plate axis platform and microscope; the three-axis platform includes: an X-axis mechanism, a Y-axis mechanism set on the X-axis mechanism, a Z-axis mechanism set on the Y-axis mechanism, and a Z-axis mechanism set on the Z-axis mechanism And the first object stage for placing the detected object, the replaceable fixture set on the first object stage for adapting various detected objects; the microscope includes multiple lenses, and the original Equipped with a second stage that can be adjusted up and down.

Further, the fixed plate is provided with a plurality of first installation holes, and the X-axis mechanism is detachably connected to the fixed plate through the plurality of first installation holes.

Further, the fixing plate is provided with a plurality of second mounting holes, and the microscope is detachably connected to the fixing plate through the plurality of second mounting holes.

Further, the first object stage may be provided with a condensing lens for condensing the detected object.

Further, the first object stage is provided with replaceable fixtures for adapting to various objects to be tested.

Further, both the three-axis platform and the microscope are connected to a control device for adjusting the position and focus of the inspected object on the first stage in cooperation with the microscope.

Further, the X-axis mechanism, the Y-axis mechanism and the Z-axis mechanism are all provided with driving devices.

Compared with the prior art, the present invention has low cost, high practicability, and can maximize the application of the microscope to various scenes; it has the first stage set on the three-axis platform and the first Two stages, realize multi-purpose of one machine; the first stage can be adjusted automatically in three directions, cooperate with lenses of different magnifications of the microscope, camera and various replaceable fixtures, to carry out inspection on the objects to be tested on the first stage Automatic observation, photo analysis, etc., to adapt to different brands and different types of microscopes of the same brand, which solves the inconvenient problem of separately modifying the loading stage and Z-axis for different microscopes, and improves the practicability.

Description of drawings

Fig. 1 is a schematic structural diagram of a first use state of a preferred embodiment of the present invention;

Fig. 2 is a schematic structural diagram of a second use state of a preferred embodiment of the present invention;

Fig. 3 is a schematic structural diagram of a three-axis platform in a preferred embodiment of the present invention.

Fig. 4 is a schematic structural view of the upper part of a replaceable fixture adapted to multiple detected objects according to a preferred embodiment of the present invention

Fig. 5 is a schematic structural diagram of the lower part of a replaceable fixture adapted to a single detected item in a preferred embodiment of the present invention

Detailed ways

Specific embodiments of the present invention will be further described in detail below. It should be understood that the description of the embodiments of the present invention here is not intended to limit the protection scope of the present invention.

FIG. 1 of the present invention is a schematic diagram of working with the second stage 61 , and FIG. 2 is a schematic diagram of working with the first stage 50 .

Referring to Fig. 1-Fig. 3, the present invention includes a fixed plate 10, and a detachable three-axis platform (including 20, 21, 30, 40, 50 in the accompanying drawings, the same below) arranged on the fixed plate 10 with microscope 60;

In the embodiment of the present invention, using the fixed plate 10 as a carrier, a three-axis platform is provided at the fitting position on one side of the microscope 60, so that the microscope 60 can carry out Work can also be done using the first stage 50 on the three-axis platform.

The three-axis platform includes: an X-axis mechanism 20, a Y-axis mechanism 30 disposed on the X-axis mechanism 20, a Z-axis mechanism 40 disposed on the Y-axis mechanism 30, and a Z-axis mechanism 40 disposed on the Z-axis mechanism 40. and a first stage 50 for placing the detected article; and replaceable fixtures 51 and 52 (including but not limited to );

In the embodiment of the present invention, the three-axis platform is detachably installed, and the installation position of the three-axis platform is adjusted according to the detection requirements; the X-axis mechanism 20 can drive the first object stage 50 to move laterally, so The Y-axis mechanism 30 can drive the first object stage 50 to move longitudinally, and the Z-axis mechanism 40 can drive the first object stage 50 to move up and down; the above-mentioned three-axis platform drives the first object stage 50 moves below the lens 62 to perform detection work, and when the first object stage 50 is used for work, the second object stage 61 is adjusted to be below the first object stage 50 to avoid.

The microscope 60 includes a plurality of lenses 62, and a second stage 61 that can be adjusted up and down;

In the embodiment of the present invention, the second stage 61 is provided with the microscope; the microscope 60 is detachably installed, and the installation position can be changed according to the requirement; it should be noted that the second stage 61 It can be customized to meet the detection requirements of various specifications.

Further, the fixed plate 10 is provided with a plurality of first installation holes 11, and the X-axis mechanism 20 is detachably connected to the fixed plate 10 through the plurality of first installation holes 11;

In the embodiment of the present invention, a plurality of first threaded holes (not shown, the same below) are provided below the X-axis mechanism 20, and the plurality of first threaded holes match the first mounting hole 11, As shown in the figure, the three-axis platform can move to a limited extent on the fixed plate 10, and then lock the three-axis platform through the first mounting hole 11 and the first threaded hole for matching the Microscope 60 job requirements.

Further, the fixed plate 10 is provided with a plurality of second mounting holes 12, and the microscope 60 is detachably connected to the fixed plate 10 through the plurality of second mounting holes 12;

In the embodiment of the present invention, a plurality of second threaded holes (not shown, the same below) are provided below the microscope 60, and the plurality of second threaded holes match the second mounting hole 12, as shown in FIG. As shown, the microscope 60 can move to a limited extent on the fixed plate 10, and then lock the microscope 60 through the second mounting hole 12 and the second threaded hole for adapting to the Describe the working requirements of the microscope 60 itself.

Further, both the first object stage 50 and the second object stage 61 are provided with light focusing holes (not shown, the same below) for concentrating the detected objects and for limiting the A clip (not shown, the same below) for detecting the movement of the object; the first object stage 50 and the second object stage 61 share or each have a condenser lens for collecting light on the object to be detected.

In the embodiment of the present invention, the first object stage 50 or the second object stage 61 is located between the spotlight and the lens of the microscope 60, the spotlight of the microscope 60 is located below the focus hole, and the lens 62 of the microscope 60 is located in the focus hole The top of the object to be detected is focused to facilitate the lens 62 of the microscope 60 to observe it; the clip will limit the object to be detected on the first stage 50 or the second stage 61 to prevent being detected. Detect item movement.

Further, the microscope 60 is provided with an adjustment device 63 for controlling the up and down movement of the second stage 61;

In the embodiment of the present invention, the Z-axis position of the second stage 61 can be adjusted by the adjusting device 63 , which can realize the focusing of the lens 62 or avoid the first stage 50 .

Further, the three-axis platform and the microscope 60 are connected to a control device (not shown, the same below), and are used to cooperate with the microscope 60 to focus on the detected object on the first stage 50 and position adjustment;

In the embodiment of the present invention, after the detected object is placed on the first stage 50, the three-axis platform is automatically adjusted by the control device to move the detected object below the lens 62, and Focusing and focusing; in addition, the control device can also control the second stage 61 to focus and adjust.

Further, the first object stage 50 is provided with replaceable fixtures 51 or 52 for adapting to various detected objects.

Further, the X-axis mechanism 20, the Y-axis mechanism 30 and the Z-axis mechanism 40 are all provided with driving devices (not shown, the same below);

In the embodiment of the present invention, the driving device is controlled by the control device without manual operation.

In summary, the present invention discloses a three-axis automatic stage that can be adapted to various microscopes, including a fixed plate, and a detachable three-axis platform and microscope arranged on the fixed plate; the three-axis The axis platform includes: an X-axis mechanism, a Y-axis mechanism set on the X-axis mechanism, a Z-axis mechanism set on the Y-axis mechanism, and a Z-axis mechanism set on the Z-axis mechanism for placing the detected The first stage of the article; the microscope includes multiple lenses and a second stage that can be adjusted up and down. The present invention has the first stage set on the three-axis platform and the second stage provided on the microscope, so that one machine can be used for multiple purposes. The camera can automatically observe and take pictures of the detected objects on the first stage, so as to adapt to different brands and models of microscopes, and solve the problem of inconvenient modification of the stage and Z-axis for different microscopes, and improve practicality.

The above are only preferred embodiments of the present invention, and are not intended to limit the protection scope of the present invention. Any modification, equivalent replacement or improvement within the spirit of the present invention is covered by the claims of the present invention.

Claims

A three-axis automatic stage that can be adapted to various microscopes is used for the microscope to automatically adjust the position and focal length of the object to be detected, so as to cooperate with the microscope for automatic observation, photographing and analysis, and is characterized in that:

It includes a fixed plate, and a detachable three-axis platform and a microscope arranged on the fixed plate;

The three-axis platform includes: an X-axis mechanism, a Y-axis mechanism arranged on the X-axis mechanism, a Z-axis mechanism arranged on the Y-axis mechanism, and a Z-axis mechanism arranged on the Z-axis mechanism for placing the The first stage of the object to be detected and the replaceable fixture arranged on the first stage for adapting various objects to be detected;

The microscope includes a plurality of lenses, and a second stage that comes with the microscope.
The three-axis automatic stage adaptable to various microscopes according to claim 1, wherein the fixed plate is provided with a plurality of first mounting holes, and the X-axis mechanism passes through a plurality of the first The mounting hole is detachably connected to the fixing plate.
The three-axis automatic stage adaptable to various microscopes according to claim 1, wherein the fixed plate is provided with a plurality of second mounting holes, and the microscope passes through a plurality of the second mounting holes It is detachably connected to the fixing plate.
The three-axis automatic stage adaptable to a variety of microscopes according to claim 1, wherein the first stage is provided with replaceable fixtures for adapting various detected objects; The first object stage and the second object stage share or respectively have a condensing mirror for condensing the detected object.
The three-axis automatic stage that can be adapted to various microscopes according to claim 4 is characterized in that, the microscope is provided with a self-contained z-axis adjustment device for controlling the movement of the second stage Move up and down so that the first stage automatically enters and falls to the designated position when automatic adjustment is required; while the first stage returns to the initial position when manual adjustment is required, and the second stage is manually raised to the designated position.
The three-axis automatic stage adaptable to various microscopes according to claim 5, wherein the three-axis platform is connected with a control device for cooperating with the pair of microscopes in the first loading stage The detected items on the stage are adjusted for focus and position.
The three-axis automatic stage adaptable to various microscopes according to claim 6, wherein the X-axis mechanism, the Y-axis mechanism and the Z-axis mechanism are all provided with driving devices.