WO2023031315A3 - New isolated bat sars-cov able to infect human cells and harboring receptor-binding domains close to sars-cov-2 - Google Patents

New isolated bat sars-cov able to infect human cells and harboring receptor-binding domains close to sars-cov-2 Download PDF

Info

Publication number
WO2023031315A3
WO2023031315A3 PCT/EP2022/074279 EP2022074279W WO2023031315A3 WO 2023031315 A3 WO2023031315 A3 WO 2023031315A3 EP 2022074279 W EP2022074279 W EP 2022074279W WO 2023031315 A3 WO2023031315 A3 WO 2023031315A3
Authority
WO
WIPO (PCT)
Prior art keywords
cov
sars
harboring
receptor
binding domains
Prior art date
Application number
PCT/EP2022/074279
Other languages
French (fr)
Other versions
WO2023031315A8 (en
WO2023031315A2 (en
Inventor
Marc Eloit
Sarah TEMMAM
Original Assignee
Institut Pasteur
Ecole Nationale Veterinaire De Maisons Alfort
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur, Ecole Nationale Veterinaire De Maisons Alfort filed Critical Institut Pasteur
Publication of WO2023031315A2 publication Critical patent/WO2023031315A2/en
Publication of WO2023031315A3 publication Critical patent/WO2023031315A3/en
Publication of WO2023031315A8 publication Critical patent/WO2023031315A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Novel SARS-CoV proteins and nucleic acids, useful for diagnostic and immunogenic applications.
PCT/EP2022/074279 2021-09-03 2022-09-01 New isolated bat sars-cov able to infect human cells and harboring receptor-binding domains close to sars-cov-2 WO2023031315A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163240535P 2021-09-03 2021-09-03
US63/240,535 2021-09-03

Publications (3)

Publication Number Publication Date
WO2023031315A2 WO2023031315A2 (en) 2023-03-09
WO2023031315A3 true WO2023031315A3 (en) 2023-04-13
WO2023031315A8 WO2023031315A8 (en) 2023-06-08

Family

ID=83400765

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2022/074279 WO2023031315A2 (en) 2021-09-03 2022-09-01 New isolated bat sars-cov able to infect human cells and harboring receptor-binding domains close to sars-cov-2

Country Status (1)

Country Link
WO (1) WO2023031315A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210268101A1 (en) * 2020-03-02 2021-09-02 Cel-Sci Corporation NOVEL PEPTIDES FOR VACCINATION AND TREATMENT OF 2019-nCoV INFECTIONS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210268101A1 (en) * 2020-03-02 2021-09-02 Cel-Sci Corporation NOVEL PEPTIDES FOR VACCINATION AND TREATMENT OF 2019-nCoV INFECTIONS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRANDÃO P E ET AL: "Molecular analysis of Brazilian strains of bovine coronavirus (BCoV) reveals a deletion within the hypervariable region of the S1 subunit of the spike glycoprotein also found in human coronavirus OC43", ARCHIVES OF VIROLOGY ; OFFICIAL JOURNAL OF THE VIROLOGY DIVISIONOF THE INTERNATIONAL UNION OF MICROBIOLOGICAL SOCIETIES, SPRINGER-VERLAG, VI, vol. 151, no. 9, 3 April 2006 (2006-04-03), pages 1735 - 1748, XP019430567, ISSN: 1432-8798, DOI: 10.1007/S00705-006-0752-9 *
CAN HÜSEYIN ET AL: "In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19", SCIENTIFIC REPORTS, 28 December 2020 (2020-12-28), England, pages 22387 - 22387, XP055944098, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769971/pdf/41598_2020_Article_79645.pdf> [retrieved on 20220719], DOI: 10.1038/s41598-020-79645-9 *
LOW ZHENG YAO ET AL: "SARS coronavirus outbreaks past and present-a comparative analysis of SARS-CoV-2 and its predecessors", VIRUS GENES, KLUWER ACADEMIC PUBLISHERS, BOSTON, US, vol. 57, no. 4, 1 June 2021 (2021-06-01), pages 307 - 317, XP037502305, ISSN: 0920-8569, [retrieved on 20210601], DOI: 10.1007/S11262-021-01846-9 *
XIAO KANGPENG ET AL: "Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins", BIORXIV, 20 February 2020 (2020-02-20), XP093018965, Retrieved from the Internet <URL:https://www.biorxiv.org/content/10.1101/2020.02.17.951335v1.full.pdf> [retrieved on 20230130], DOI: 10.1101/2020.02.17.951335 *

Also Published As

Publication number Publication date
WO2023031315A8 (en) 2023-06-08
WO2023031315A2 (en) 2023-03-09

Similar Documents

Publication Publication Date Title
WO2019126634A3 (en) Targeted integration of nucleic acids
MX2020004578A (en) Casz compositions and methods of use.
WO2019224025A3 (en) Antagonizing cd73 antibody
MX2023003255A (en) Crispr-cas effector polypeptides and methods of use thereof.
BR112019006388A2 (en) rna-guided nucleic acid modifying enzymes and methods of using them
BR112022019782A2 (en) ANN CONSTRUCTS AND THEIR USES
EP4275698A3 (en) Anti-tigit antibodies and methods of use thereof
MX2020013977A (en) Chimeric transmembrane proteins and uses thereof.
CY1112105T1 (en) Immunogenic Bacterial Bladders with External Membrane Proteins
WO2012045082A3 (en) Engineered nucleic acids and methods of use thereof
MX2009012609A (en) Compositions and methods for producing bioactive fusion proteins.
BR112016023304A2 (en) recombinant host cell engineered to overexpress helper proteins
BRPI0516489A (en) lactic acid and double-bacteria bacteria products with a high degree of dispersibility
WO2018053365A8 (en) Methods of nucleic acid sample preparation for analysis of cell-free dna
WO2003082183A3 (en) Protein-based streptococcus pneumoniae vaccines
ATE522541T1 (en) BACTERIAL ADHESIN CONFORMERS
AR033574A1 (en) A BACTERIAL CEPA OF THE LACTIC BACTERIA GROUP CAPABLE OF REDUCING THE TREND OF AN INDIVIDUAL TO DEVELOP ALLERGIC REACTIONS, FOOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND THE VACCINES CONTAINING IT
BR112022010179A2 (en) YELLOW FEVER ANTI-VIRUS ANTIBODIES, AND METHODS OF THEIR GENERATION AND USE
WO2020030984A3 (en) Compositions and methods for genome engineering with cas12a proteins
WO2016130628A8 (en) Griffithsin mutants
MX2022002315A (en) Anti-cd96 antibodies and methods of use thereof.
WO2020070678A3 (en) Antibodies specific for human and cynomolgus apoc3 and methods of use thereof
AU2001275438A1 (en) Stable (fixed) forms of viral capsid proteins, fusion proteins and uses thereof
WO2008151633A3 (en) Vectors for vaccines against lentivirus infections
CN104450765A (en) Integron In1069

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 22773600

Country of ref document: EP

Kind code of ref document: A2