WO2023031062A3 - Drug delivery system - Google Patents

Drug delivery system Download PDF

Info

Publication number
WO2023031062A3
WO2023031062A3 PCT/EP2022/073856 EP2022073856W WO2023031062A3 WO 2023031062 A3 WO2023031062 A3 WO 2023031062A3 EP 2022073856 W EP2022073856 W EP 2022073856W WO 2023031062 A3 WO2023031062 A3 WO 2023031062A3
Authority
WO
WIPO (PCT)
Prior art keywords
infusion needle
housing
penetration area
delivery system
drug delivery
Prior art date
Application number
PCT/EP2022/073856
Other languages
French (fr)
Other versions
WO2023031062A2 (en
Inventor
Peter Forsell
Original Assignee
Medicaltree Patents Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2021/073893 external-priority patent/WO2022043555A1/en
Application filed by Medicaltree Patents Ltd filed Critical Medicaltree Patents Ltd
Priority to EP22769650.7A priority Critical patent/EP4395848A2/en
Priority to CA3228283A priority patent/CA3228283A1/en
Priority to JP2024513976A priority patent/JP2024534219A/en
Priority to AU2022336969A priority patent/AU2022336969A1/en
Priority to AU2023222162A priority patent/AU2023222162A1/en
Priority to PCT/EP2023/053894 priority patent/WO2023156523A1/en
Publication of WO2023031062A2 publication Critical patent/WO2023031062A2/en
Publication of WO2023031062A3 publication Critical patent/WO2023031062A3/en
Priority to SE2450190A priority patent/SE2450190A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291—Shafts with additional lateral openings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3295—Multiple needle devices, e.g. a plurality of needles arranged coaxially or in parallel
    • A61M5/3298—Needles arranged in parallel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/26—Penis implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A61M2005/14284—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1583—Needle extractors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/04—General characteristics of the apparatus implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3507—Communication with implanted devices, e.g. external control
    • A61M2205/3515—Communication with implanted devices, e.g. external control using magnetic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3561—Range local, e.g. within room or hospital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3584—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using modem, internet or bluetooth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8237—Charging means
    • A61M2205/8243—Charging means by induction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/16—Male reproductive, genital organs
    • A61M2210/167—Penis

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The present disclosure relates to an at least partly implantable system for injecting a substance into a patient's body, comprising: - a housing adapted for implantation inside the patient's body, the housing having an outer wall with a penetration area, - at least one infusion needle disposed in the housing, and - a drive unit arranged for advancing and retracting the at least one infusion needle in opposite advancing and retracting directions so that a tip end of the at least one infusion needle penetrates, upon advancement of the at least one infusion needle, said penetration area so as to allow for injecting the substance through said penetration area via the at least one infusion needle.
PCT/EP2022/073856 2021-08-30 2022-08-26 Drug delivery system WO2023031062A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP22769650.7A EP4395848A2 (en) 2021-08-30 2022-08-26 Drug delivery system
CA3228283A CA3228283A1 (en) 2021-08-30 2022-08-26 Drug delivery system
JP2024513976A JP2024534219A (en) 2021-08-30 2022-08-26 Drug Delivery Systems
AU2022336969A AU2022336969A1 (en) 2021-08-30 2022-08-26 Drug delivery system
AU2023222162A AU2023222162A1 (en) 2022-02-18 2023-02-16 Drug delivery system
PCT/EP2023/053894 WO2023156523A1 (en) 2022-02-18 2023-02-16 Drug delivery system
SE2450190A SE2450190A1 (en) 2022-02-18 2024-02-16 Drug delivery system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2021/073893 WO2022043555A1 (en) 2020-08-31 2021-08-30 Providing remotely energy for an implant comprising a capacitor for providing necessary energy bursts for the energy consuming parts of the implant
EPPCT/EP2021/073893 2021-08-30
SE2250190-2 2022-02-18
SE2250190 2022-02-18

Publications (2)

Publication Number Publication Date
WO2023031062A2 WO2023031062A2 (en) 2023-03-09
WO2023031062A3 true WO2023031062A3 (en) 2023-04-13

Family

ID=83319102

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2022/073856 WO2023031062A2 (en) 2021-08-30 2022-08-26 Drug delivery system

Country Status (1)

Country Link
WO (1) WO2023031062A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024170786A1 (en) * 2023-02-16 2024-08-22 Medicaltree Patents Ltd. Drug delivery system

Citations (18)

* Cited by examiner, † Cited by third party
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US3720021A (en) * 1970-12-22 1973-03-13 S Wada Method for removing cutting and grinding burrs from machined injection needle tubes
US5817074A (en) * 1995-10-23 1998-10-06 Racz; Gabor J. Stellate block needle
US6464889B1 (en) * 1996-01-22 2002-10-15 Etex Corporation Surface modification of medical implants
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US20080175980A1 (en) * 2006-11-09 2008-07-24 Jichao Sun Medical Device Coating Process
US20080200421A1 (en) * 2007-02-21 2008-08-21 Zhao Jonathon Z Coating for a medical device having an anti-thrombotic conjugate
EP1960027A1 (en) * 2005-11-02 2008-08-27 Injectica AG Implantable infusion device with advanceable and retractable needle
EP2058020A2 (en) * 2005-02-01 2009-05-13 Intelliject, LLC Devices, systems, and methods for medicament delivery
US20110196301A1 (en) * 2008-10-10 2011-08-11 Milux Holding S.A. Infusion of drugs
US20110270232A1 (en) * 2008-10-10 2011-11-03 Milux Holding S.A. Infusion of drugs
US20110278948A1 (en) * 2008-11-21 2011-11-17 Milux Holdings SA System for supplying energy
US20140200477A1 (en) * 2011-10-31 2014-07-17 Neuropace, Inc. Establishing secure communication between an implantable medical device and an external device
US20140266022A1 (en) * 2013-03-15 2014-09-18 Sequana Medical Ag Systems and methods for regulating inductive energy transfer to an implantable system
EP3087679A1 (en) * 2013-12-27 2016-11-02 Samsung Electronics Co., Ltd. Protective cover and electronic device having it
US20170246404A1 (en) * 2016-02-26 2017-08-31 Case.MD Apparatus and method for injecting fluid into a subject
US20180280708A1 (en) * 2015-07-31 2018-10-04 University Of Ulster Transcutaneous Energy Transfer Systems and Methods
US20190022306A1 (en) * 2016-02-12 2019-01-24 Amgen Inc. Drug delivery device, method of manufacture, and method of use
US20190160254A1 (en) * 2017-11-15 2019-05-30 Alcyone Lifesciences, Inc. Drug Delivery Systems and Methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3005986T (en) 2008-10-10 2021-12-29 Medicaltree Patent Ltd Infusion of drugs

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US3720021A (en) * 1970-12-22 1973-03-13 S Wada Method for removing cutting and grinding burrs from machined injection needle tubes
US5817074A (en) * 1995-10-23 1998-10-06 Racz; Gabor J. Stellate block needle
US6464889B1 (en) * 1996-01-22 2002-10-15 Etex Corporation Surface modification of medical implants
EP2058020A2 (en) * 2005-02-01 2009-05-13 Intelliject, LLC Devices, systems, and methods for medicament delivery
EP1960027A1 (en) * 2005-11-02 2008-08-27 Injectica AG Implantable infusion device with advanceable and retractable needle
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US20080175980A1 (en) * 2006-11-09 2008-07-24 Jichao Sun Medical Device Coating Process
US20080200421A1 (en) * 2007-02-21 2008-08-21 Zhao Jonathon Z Coating for a medical device having an anti-thrombotic conjugate
US20110196301A1 (en) * 2008-10-10 2011-08-11 Milux Holding S.A. Infusion of drugs
US20110270232A1 (en) * 2008-10-10 2011-11-03 Milux Holding S.A. Infusion of drugs
US20110278948A1 (en) * 2008-11-21 2011-11-17 Milux Holdings SA System for supplying energy
US20140200477A1 (en) * 2011-10-31 2014-07-17 Neuropace, Inc. Establishing secure communication between an implantable medical device and an external device
US20140266022A1 (en) * 2013-03-15 2014-09-18 Sequana Medical Ag Systems and methods for regulating inductive energy transfer to an implantable system
EP3087679A1 (en) * 2013-12-27 2016-11-02 Samsung Electronics Co., Ltd. Protective cover and electronic device having it
US20180280708A1 (en) * 2015-07-31 2018-10-04 University Of Ulster Transcutaneous Energy Transfer Systems and Methods
US20190022306A1 (en) * 2016-02-12 2019-01-24 Amgen Inc. Drug delivery device, method of manufacture, and method of use
US20170246404A1 (en) * 2016-02-26 2017-08-31 Case.MD Apparatus and method for injecting fluid into a subject
US20190160254A1 (en) * 2017-11-15 2019-05-30 Alcyone Lifesciences, Inc. Drug Delivery Systems and Methods

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DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; July 2020 (2020-07-01), ROBERTS TERYN R ET AL: "Heparin-Free Extracorporeal Life Support Using Tethered Liquid Perfluorocarbon: A Feasibility and Efficacy Study.", XP002808734, Database accession no. NLM31453831 *
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