WO2023024587A1 - Dispositif de stimulation de nerf hypoglosse - Google Patents
Dispositif de stimulation de nerf hypoglosse Download PDFInfo
- Publication number
- WO2023024587A1 WO2023024587A1 PCT/CN2022/092695 CN2022092695W WO2023024587A1 WO 2023024587 A1 WO2023024587 A1 WO 2023024587A1 CN 2022092695 W CN2022092695 W CN 2022092695W WO 2023024587 A1 WO2023024587 A1 WO 2023024587A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stimulation
- hypoglossal nerve
- coil
- controller
- external device
- Prior art date
Links
- 210000001169 hypoglossal nerve Anatomy 0.000 title claims abstract description 101
- 230000007383 nerve stimulation Effects 0.000 title claims abstract description 52
- 230000000638 stimulation Effects 0.000 claims abstract description 179
- 238000001727 in vivo Methods 0.000 claims abstract description 17
- 238000004891 communication Methods 0.000 claims abstract description 16
- 208000008784 apnea Diseases 0.000 claims description 36
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 32
- 230000004044 response Effects 0.000 claims description 30
- 230000004936 stimulating effect Effects 0.000 claims description 29
- 239000003990 capacitor Substances 0.000 claims description 19
- 210000005036 nerve Anatomy 0.000 claims description 4
- 230000010363 phase shift Effects 0.000 claims description 4
- 230000006698 induction Effects 0.000 abstract description 10
- 230000005540 biological transmission Effects 0.000 abstract description 8
- 238000000338 in vitro Methods 0.000 abstract description 7
- 238000000034 method Methods 0.000 description 15
- 238000010586 diagram Methods 0.000 description 12
- 230000006378 damage Effects 0.000 description 8
- 208000001797 obstructive sleep apnea Diseases 0.000 description 8
- 230000033001 locomotion Effects 0.000 description 7
- 238000001356 surgical procedure Methods 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 5
- 230000000241 respiratory effect Effects 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000002513 implantation Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 208000000860 Compassion Fatigue Diseases 0.000 description 3
- 238000005265 energy consumption Methods 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 206010021079 Hypopnoea Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
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- 238000012986 modification Methods 0.000 description 2
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- 230000000414 obstructive effect Effects 0.000 description 2
- 230000037081 physical activity Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000000779 thoracic wall Anatomy 0.000 description 2
- 208000002381 Brain Hypoxia Diseases 0.000 description 1
- 208000004221 Multiple Trauma Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041235 Snoring Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
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- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000002990 hypoglossal effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
Abstract
La présente demande se rapporte au domaine des instruments médicaux, et divulgue un dispositif de stimulation de nerf hypoglosse, comprenant un dispositif in vivo et un dispositif in vitro. Le dispositif in vivo est monté au niveau d'une extrémité distale d'un nerf hypoglosse, et comprend une puce intégrée, une électrode de stimulation et une bobine flexible ; la puce intégrée est reliée à l'électrode de stimulation et à la bobine flexible, respectivement ; la bobine flexible est utilisée pour recevoir des informations d'énergie et de stimulation envoyées par le dispositif in vitro ; la puce intégrée est utilisée pour générer une impulsion de stimulation selon les informations d'énergie et de stimulation reçues ; et l'électrode de stimulation est utilisée pour transmettre l'impulsion de stimulation au nerf hypoglosse. Le dispositif in vitro est monté sur la surface de corps au-dessus du dispositif in vivo, et comprend une bobine et un dispositif de commande ; le dispositif de commande est relié à la bobine, et est utilisé pour générer des informations d'énergie et de stimulation ; et la bobine est utilisée pour transmettre les informations d'énergie et de stimulation au dispositif in vivo. Le dispositif de stimulation de nerf hypoglosse est divisé en dispositif in vivo et dispositif in vitro qui exploitent une liaison d'induction magnétique formée par la bobine in vivo et la bobine in vitro pour réaliser une communication et une transmission d'énergie, la taille du dispositif in vivo est réduite, et la praticité et la sécurité sont améliorées.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110970411.3A CN113856047B (zh) | 2021-08-23 | 2021-08-23 | 舌下神经刺激装置 |
| CN202110970411.3 | 2021-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2023024587A1 true WO2023024587A1 (fr) | 2023-03-02 |
Family
ID=78988013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2022/092695 WO2023024587A1 (fr) | 2021-08-23 | 2022-05-13 | Dispositif de stimulation de nerf hypoglosse |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN113856047B (fr) |
| WO (1) | WO2023024587A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113856047B (zh) * | 2021-08-23 | 2023-05-26 | 西湖大学 | 舌下神经刺激装置 |
| CN117065210A (zh) * | 2023-05-31 | 2023-11-17 | 上海杉翎医疗科技有限公司 | 用于刺激外周神经的装置 |
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| CN107019495A (zh) * | 2017-03-13 | 2017-08-08 | 北京航空航天大学 | 基于智能手机与鼻贴式呼吸传感器的呼吸暂停检测与预警装置和方法 |
| CN108463163A (zh) * | 2015-10-21 | 2018-08-28 | 诺伊斯佩拉医疗有限公司 | 用于刺激治疗的装置、系统和方法 |
| US20200238084A1 (en) * | 2019-01-29 | 2020-07-30 | Synapse Biomedical, Inc. | Systems and methods for treating sleep apnea using neuromodulation |
| CN113856047A (zh) * | 2021-08-23 | 2021-12-31 | 西湖大学 | 舌下神经刺激装置 |
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| AU2001216840A1 (en) * | 2000-11-16 | 2002-05-27 | Polyvalor S.E.C. | Body electronic implant and artificial vision system thereof |
| CA2641821C (fr) * | 2006-02-16 | 2017-10-10 | Imthera Medical, Inc. | Appareil, systeme et procede rfid de traitement therapeutique d'un patient |
| US7660632B2 (en) * | 2006-06-30 | 2010-02-09 | Ric Investments, Llc | Method and apparatus for hypoglossal nerve stimulation |
| US8626299B2 (en) * | 2008-01-31 | 2014-01-07 | Enopace Biomedical Ltd. | Thoracic aorta and vagus nerve stimulation |
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| US8602999B2 (en) * | 2009-09-16 | 2013-12-10 | Darrin J. Young | Implantable flat blood pressure sensing cuff structure and implantable blood pressure monitoring device using the cuff structure |
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| JP2014508600A (ja) * | 2011-02-24 | 2014-04-10 | ボストン サイエンティフィック ニューロモデュレイション コーポレイション | 回路基板及びコネクタを備えた埋込み可能な神経刺激器 |
| WO2014106023A1 (fr) * | 2012-12-28 | 2014-07-03 | Cardiac Pacemakers, Inc. | Manchon de stimulation et outil d'implantation |
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| US10406365B2 (en) * | 2014-01-15 | 2019-09-10 | Board Of Regents, The University Of Texas System | Regenerative interface electrode |
| US10195428B2 (en) * | 2015-09-29 | 2019-02-05 | Medtronic, Inc. | Neural stimulation to treat sleep apnea |
| US11471681B2 (en) * | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
| WO2017127758A1 (fr) * | 2016-01-20 | 2017-07-27 | Setpoint Medical Corporation | Microstimulateurs implantables et systèmes de recharge par induction |
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| US10933248B2 (en) * | 2016-11-04 | 2021-03-02 | Galvani Bioelectronics Limited | System for wirelessly coupling in vivo |
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| WO2019046658A1 (fr) * | 2017-08-30 | 2019-03-07 | The Alfred E. Mann Foundation For Scientific Research | Systèmes et procédés de stimulation pour recruter sélectivement des fascicules dans un tronc nerveux hypoglosse |
| US20200238048A1 (en) * | 2019-01-29 | 2020-07-30 | Cure Medical Llc | Easy to use urinary catheter |
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| US11559686B2 (en) * | 2019-09-06 | 2023-01-24 | Nextern, Inc. | Systems, devices, components and methods for the delivery of electrical stimulation to cranial nerves to treat mood or mood affective disorders |
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2021
- 2021-08-23 CN CN202110970411.3A patent/CN113856047B/zh active Active
-
2022
- 2022-05-13 WO PCT/CN2022/092695 patent/WO2023024587A1/fr unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108463163A (zh) * | 2015-10-21 | 2018-08-28 | 诺伊斯佩拉医疗有限公司 | 用于刺激治疗的装置、系统和方法 |
| CN107019495A (zh) * | 2017-03-13 | 2017-08-08 | 北京航空航天大学 | 基于智能手机与鼻贴式呼吸传感器的呼吸暂停检测与预警装置和方法 |
| US20200238084A1 (en) * | 2019-01-29 | 2020-07-30 | Synapse Biomedical, Inc. | Systems and methods for treating sleep apnea using neuromodulation |
| CN113856047A (zh) * | 2021-08-23 | 2021-12-31 | 西湖大学 | 舌下神经刺激装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113856047B (zh) | 2023-05-26 |
| CN113856047A (zh) | 2021-12-31 |
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