WO2023001151A1 - Utilisation d'un appareil d'émission d'ondes de choc électromagnétiques dans la fabrication d'un dispositif pour le traitement de maladies neurodégénératives - Google Patents
Utilisation d'un appareil d'émission d'ondes de choc électromagnétiques dans la fabrication d'un dispositif pour le traitement de maladies neurodégénératives Download PDFInfo
- Publication number
- WO2023001151A1 WO2023001151A1 PCT/CN2022/106527 CN2022106527W WO2023001151A1 WO 2023001151 A1 WO2023001151 A1 WO 2023001151A1 CN 2022106527 W CN2022106527 W CN 2022106527W WO 2023001151 A1 WO2023001151 A1 WO 2023001151A1
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- Prior art keywords
- shock waves
- disease
- neurodegenerative diseases
- acupuncture
- use according
- Prior art date
Links
- 230000035939 shock Effects 0.000 title claims abstract description 28
- 230000004770 neurodegeneration Effects 0.000 title claims abstract description 18
- 208000015122 neurodegenerative disease Diseases 0.000 title claims abstract description 18
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 4
- 238000001467 acupuncture Methods 0.000 claims abstract description 22
- 230000000694 effects Effects 0.000 claims abstract description 11
- 238000011282 treatment Methods 0.000 claims description 11
- 208000024827 Alzheimer disease Diseases 0.000 claims description 10
- 201000006474 Brain Ischemia Diseases 0.000 claims description 2
- 206010008025 Cerebellar ataxia Diseases 0.000 claims description 2
- 206010008120 Cerebral ischaemia Diseases 0.000 claims description 2
- 201000011240 Frontotemporal dementia Diseases 0.000 claims description 2
- 208000023105 Huntington disease Diseases 0.000 claims description 2
- 208000018737 Parkinson disease Diseases 0.000 claims description 2
- 208000000609 Pick Disease of the Brain Diseases 0.000 claims description 2
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims description 2
- 208000029028 brain injury Diseases 0.000 claims description 2
- 206010008118 cerebral infarction Diseases 0.000 claims description 2
- 206010015037 epilepsy Diseases 0.000 claims description 2
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 239000000523 sample Substances 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 230000000638 stimulation Effects 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 206010039966 Senile dementia Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000009213 extracorporeal shockwave therapy Methods 0.000 description 2
- 230000000955 neuroendocrine Effects 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 208000000044 Amnesia Diseases 0.000 description 1
- 102000014461 Ataxins Human genes 0.000 description 1
- 108010078286 Ataxins Proteins 0.000 description 1
- 208000026139 Memory disease Diseases 0.000 description 1
- 208000009415 Spinocerebellar Ataxias Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 201000004562 autosomal dominant cerebellar ataxia Diseases 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 210000001638 cerebellum Anatomy 0.000 description 1
- 208000010877 cognitive disease Diseases 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 206010013395 disorientation Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004179 hypothalamic–pituitary–adrenal axis Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/06—Devices for heating or cooling such points within cell-life limits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
Definitions
- the invention belongs to the technical field of modern traditional Chinese medicine, and in particular relates to the use of a device for emitting electromagnetic shock waves in preparing equipment for treating neurodegenerative diseases.
- Acupoint acupuncture is a method of inserting a needle into a patient's body at a certain point, and using acupuncture techniques such as twisting and lifting to treat diseases.
- pulse acupuncture on acupoints has been further developed in the acupuncture point treatment method, that is, electroacupuncture.
- Electroacupuncture is a method of treating diseases by using a pulse acupuncture treatment device to output pulse current, and acting on the meridian points of the human body through the needles. The stimulation of the needles is combined with the physiological effect of electricity. This method can improve the therapeutic effect of filiform needles and expand the therapeutic range of acupuncture and moxibustion.
- the working principle of the pulse acupuncture treatment instrument is the sudden change of voltage and current in a very short time, which constitutes an electric pulse. Because the pulse electricity produces an electrical physiological effect on the body, it shows various therapeutic effects.
- the pulse therapy instrument can accurately select the pulse electric waveform and stimulation intensity, maintain a long-term acupuncture feeling, and reduce the work of manual twisting. It is generally accepted by patients and is currently widely used in clinical practice.
- An extracorporeal shock wave is a mechanically pulsed pressure wave transmitted through a medium (air or gas).
- Extracorporeal shock wave therapy equipment converts the pulsed sound waves generated by pneumatics into precise ballistic shock waves, which are released to the body parts to be treated through the positioning and movement of the treatment probe.
- Extracorporeal shock wave therapy is widely used in eliminating pain in human tissue and crushing stones in the body.
- Neurodegenerative diseases are disorders of the central nervous system that result in dysfunction in the body due to the loss of neurons or their myelin sheath. Neurodegenerative diseases predominate in the elderly population, the most well-known of which is Alzheimer's disease (senile dementia), which is characterized by memory loss, spatial disorientation, cognitive dysfunction and behavioral changes. After the age of 65, the risk of developing Alzheimer's disease doubles every 5 years, and about 1 in 3 people over the age of 85 have Alzheimer's disease.
- Alzheimer's disease senile dementia
- the Chinese utility model "CN201921474022.6 Massager for Prevention of Alzheimer's Disease” discloses a massager for prevention of Alzheimer's disease, which can stimulate many acupoints on the soles of the feet through the heat generated by the electric heating wire, and stimulate the acupoints on the feet through mechanical massage , so as to achieve the effect of preventing, slowing down and treating diseases.
- the device disclosed in this utility model only adopts thermal stimulation and massage on the acupoints, and lacks deep stimulation. Therefore, its slowing effect on neurodegenerative diseases such as senile dementia is relatively limited, and it is difficult to achieve a better therapeutic effect.
- the present invention provides the use of a device for emitting shock waves in the preparation of equipment for treating neurodegenerative diseases. treating neurodegenerative diseases through physical therapy,
- the device impacts the acupoints by emitting electromagnetic shock waves, simulating the effect of acupuncture on the acupoints.
- the acupuncture point is selected from at least one of Hegu or Zusanli.
- the shock waves are low-energy shock waves.
- the energy of the low-energy shock wave is set to level3.
- the number of impacts for each acupuncture point is 500 times, and the impact time for each acupuncture point is 15 minutes.
- the impact frequency is 3 times a week.
- the neurodegenerative disease is at least one of cerebral ischemia, brain injury, epilepsy, Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, different types of spinocerebellar ataxia or Pick's disease A sort of.
- Acupuncture can not only regulate the abnormality of the neuroendocrine HPA axis, but also regulate the disorder of immune function. It has a reliable theoretical basis to explore the prevention and treatment mechanism of neurodegenerative diseases from the perspective of regulating the imbalance of neuroendocrine and immune networks.
- Low-energy shock wave therapy is currently widely used in clinical practice, and has been rapidly promoted due to its advantages of safety, rapid onset and quick effect.
- the invention adopts the directional focus therapy principle of low-energy shock waves to simulate the acupuncture effect, and provides a feasible clinical treatment approach for treating neurodegenerative diseases.
- the technical solution of the present invention has the characteristics of small toxic and side effects, simple and easy operation, meets the current situation of social and economic development in my country and clinical needs, and has important practical significance for reducing malignant diseases, improving people's quality of life, and reducing social burdens.
- the present embodiment provides a therapeutic device including a device for emitting electromagnetic shock waves for treating neurodegenerative diseases.
- the effect of acupuncture points is simulated by emitting shock waves, and the acupoints of "Hegu” and "Zusanli” are selected.
- Low-energy shock wave therapy level 3, 500 shocks per acupoint, 15 minutes of treatment, 3 times a week. The treatment lasted for 5 weeks.
- E is the shock wave energy, in millijoule (mJ); A is the shock wave action area, in cubic millimeter (mm 3 ); ⁇ is the density of the propagation medium, in kilogram per cubic meter (kg m -3 ); c is the propagation velocity in meters per second (m/s); P is the peak pressure in megapascals (MPa); t is time in seconds.
- Table 2 shows the density, sound velocity, and acoustic impedance of normal human tissue
- the invention has the characteristics of small toxic and side effects, simple operation and high application value.
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Rehabilitation Therapy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Finger-Pressure Massage (AREA)
Abstract
L'invention concerne l'utilisation d'un appareil d'émission d'ondes de choc électromagnétiques dans la fabrication d'un dispositif pour le traitement de maladies neurodégénératives. L'appareil agit sur des points d'acuponcture par émission d'ondes de choc électromagnétiques, et simule l'effet d'acupuncture sur les points d'acupuncture.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110814544 | 2021-07-19 | ||
CN202110814544.1 | 2021-07-19 |
Publications (1)
Publication Number | Publication Date |
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WO2023001151A1 true WO2023001151A1 (fr) | 2023-01-26 |
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Application Number | Title | Priority Date | Filing Date |
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PCT/CN2022/106527 WO2023001151A1 (fr) | 2021-07-19 | 2022-07-19 | Utilisation d'un appareil d'émission d'ondes de choc électromagnétiques dans la fabrication d'un dispositif pour le traitement de maladies neurodégénératives |
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WO (1) | WO2023001151A1 (fr) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150073312A1 (en) * | 2013-09-08 | 2015-03-12 | Moshe Ein-Gal | Low intensity shockwave treatment |
CN106491020A (zh) * | 2016-10-25 | 2017-03-15 | 林健锋 | 内置冲击波发生装置的足浴盆 |
CN106512219A (zh) * | 2016-10-12 | 2017-03-22 | 刘宇军 | 一种生命能量脉冲理疗仪及使用方法 |
CN106580654A (zh) * | 2016-12-21 | 2017-04-26 | 湛江经济技术开发区海滨医疗器械有限公司 | 冲击波沐足盆 |
CN106983653A (zh) * | 2017-03-21 | 2017-07-28 | 北京易通络科技有限公司 | 一种便携式冲击波通络机 |
CN109010009A (zh) * | 2018-08-29 | 2018-12-18 | 深圳市海德医疗设备有限公司 | 冲击波源装置、针灸仪和针灸仪控制方法 |
CN110652446A (zh) * | 2018-06-29 | 2020-01-07 | 成都中医药大学附属医院 | 一种穴位治疗装置 |
-
2022
- 2022-07-19 WO PCT/CN2022/106527 patent/WO2023001151A1/fr unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150073312A1 (en) * | 2013-09-08 | 2015-03-12 | Moshe Ein-Gal | Low intensity shockwave treatment |
CN106512219A (zh) * | 2016-10-12 | 2017-03-22 | 刘宇军 | 一种生命能量脉冲理疗仪及使用方法 |
CN106491020A (zh) * | 2016-10-25 | 2017-03-15 | 林健锋 | 内置冲击波发生装置的足浴盆 |
CN106580654A (zh) * | 2016-12-21 | 2017-04-26 | 湛江经济技术开发区海滨医疗器械有限公司 | 冲击波沐足盆 |
CN106983653A (zh) * | 2017-03-21 | 2017-07-28 | 北京易通络科技有限公司 | 一种便携式冲击波通络机 |
CN110652446A (zh) * | 2018-06-29 | 2020-01-07 | 成都中医药大学附属医院 | 一种穴位治疗装置 |
CN109010009A (zh) * | 2018-08-29 | 2018-12-18 | 深圳市海德医疗设备有限公司 | 冲击波源装置、针灸仪和针灸仪控制方法 |
Non-Patent Citations (1)
Title |
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REN HONGYU, WANG XING-XING; ZHENG YU; HUANG YONG: "Exploration of Regularities in Point Selection for Acupuncture Treatment of Parkinson Disease", SHANGHAI JOURNAL OF ACUPUNCTURE AND MOXIBUSTION, vol. 34, no. 1, 31 January 2015 (2015-01-31), pages 70 - 72, XP093027304, ISSN: 1005-0957, DOI: 10.13460/j.issn.1005-0957.2015.01.0070 * |
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