WO2023000415A1

WO2023000415A1 - Thrombectomy catheter

Info

Publication number: WO2023000415A1
Application number: PCT/CN2021/112424
Authority: WO
Inventors: 李培尚; 吴巍巍; 李静
Original assignee: 江苏迈得诺医疗集团有限公司
Priority date: 2021-07-19
Filing date: 2021-08-13
Publication date: 2023-01-26
Also published as: CN113509238A

Abstract

A thrombectomy catheter, which relates to the field of vascular interventional instruments, and comprises a catheter body (2), the catheter body (2) being provided with an expansion end (3) and an exposed end (4); the expansion end (3) is located at the end of the catheter body (2) that enters into a blood vessel during a thrombectomy operation; and the exposed end (4) is located on the other end of the catheter body (2) opposite to the expansion end (3), and is suitable for remaining outside of the human body during the thrombectomy operation. The expansion end (3) comprises: a plurality of petal-shaped pieces (5), which are disposed at an end portion of the catheter body (2), and the petal-shaped pieces (5) are suitable for opening to the periphery of the catheter body (2) under the action of an external force. The thrombectomy catheter also comprises pull wires (6), one end of the pull wires (6) being connected to the petal-shaped pieces (5), and the other end of the pull wires (6) extending to the exposed end (4) of the catheter body (2). The thrombectomy catheter can control the opening range of the catheter at a thrombectomy site, meet the requirements of vessels of different diameters, and also has the advantages of being less painful for patients, stable to operate, and the like.

Description

A thrombectomy catheter

technical field

The present application relates to the field of vascular intervention devices, in particular to a thrombectomy catheter.

Background technique

Mechanical thrombectomy is a new option for thrombus at present, that is, a catheter that can remove thrombus is inserted into the blood vessel, and negative pressure is applied to the catheter outside the body to suck the thrombus out of the body. The thrombus removal catheter in the prior art is usually provided with an expandable end at one end of the human body. The catheter is provided with components such as a thrombus removal guide wire and a thrombus breaking guide wire. The chips are pulled out of the catheter. The expandable end is usually formed of a basket-like structure woven by memory metal wires. The basket-like structure can be opened under the action of external force or temperature. The inner wall fits tightly to prevent thrombus from escaping through the gap between the blood vessel and the catheter.

However, the opening range of the thrombectomy catheter in the prior art is usually fixed, so when facing different groups of people or blood vessels of different thicknesses, since the opening range of the catheter is constant, there may be a gap between the catheter and the inner wall of the blood vessel. Incomplete fit, or risk of overstretching the vessel.

Contents of the invention

Therefore, the technical problem to be solved in this application is to overcome the defect that the blood vessel and the end of the catheter will not fit completely or the catheter excessively stretches the blood vessel during the thrombectomy operation of the thrombectomy catheter in the prior art, and then provide a A thrombectomy catheter capable of overcoming the above-mentioned defects.

According to one aspect of the present application, a kind of thrombectomy catheter is provided, comprising:

Tube body;

The expansion end, located at one end of the tube body, is suitable for entering the blood vessel during thrombectomy;

The exposed end is located on the other end of the tube body opposite to the expanded end, and is suitable for staying outside the human body during thrombectomy;

A traction line, one end of the traction line is connected to the petal, and the other end extends to the exposed end of the tube body.

Several petals at the expansion end are arranged at the end of the tube body;

The petals are adapted to expand toward the outer periphery of the tube body under the traction of the traction wire.

Optionally, a traction member is also included, which is arranged at the exposed end of the pipe body, connected with the traction line, suitable for pulling the traction line, and fixing the dragging length of the traction line.

Optionally, the traction member includes:

The threaded section is arranged on the exposed end of the pipe body;

The screw nut is set on the outside of the pipe body and engages with the threaded section;

The sliding ring is set on the outside of the pipe body, the sliding ring is embedded in the nut, and is suitable for sliding along the pipe body driven by the nut, and the sliding ring is connected with the pulling wire.

Optionally, the pulling wire passes through the tube body and is relatively slidably arranged with the tube body.

Optionally, the pulling wire is connected to a side of the petal member away from the exposed end.

Optionally, there are at least three petals.

Optionally, the cross section of the petal is arc-shaped.

Optionally, different petals overlap each other, and the same petal overlaps the inner side and the outer side of the other two petals that are adjacent to it respectively.

Optionally, the expansion end also includes:

The elastic segment is wrapped on the outside of the petal, and is suitable for being driven to expand elastically when the petal is opened.

Optionally, also include:

The base is arranged on the exposed end of the tube body and communicates with the tube body.

The technical solution provided by the application has the following technical effects:

1. A thrombectomy catheter, comprising a tube body, the tube body is provided with an expansion end and an exposed end, the expansion end is located at the end of the tube body that enters the blood vessel during the thrombectomy operation; the exposed end is located at the other end of the tube body opposite to the expansion end One end is suitable for staying outside the human body during thrombectomy; the expansion end includes: several petal-like parts, which are arranged at the end of the tube body, and the petal-like parts are suitable for stretching toward the outer circumference of the tube body under the action of external force. Open; the thrombectomy catheter also includes a pulling wire, one end of the pulling wire is connected to the petal, and the other end extends to the exposed end of the tube body.

When the above-mentioned thrombectomy catheter is used for thrombectomy, the catheter enters the blood vessel, and the flap at the front end of the catheter body can be opened by pulling the traction wire, so that the front end of the catheter can be opened to prop up the blood vessel. At this time, adjusting the pull-out length of the pulling wire can control the opening range of the petal, so that the opening range of the entire expansion end can be controlled. When operating on blood vessels of different thicknesses, it can meet their needs.

2. The thrombectomy catheter provided by this application also includes a traction member, which is arranged on the exposed end of the tube body and connected with the traction wire, which is suitable for pulling the traction wire and fixing the length of the traction wire. The traction member includes: a threaded section, which is arranged on the exposed end of the pipe body; a nut, which is sleeved on the outside of the pipe body, and engages with the threaded section; a sliding ring, which is sleeved on the outside of the pipe body, and the sliding ring is embedded in the nut Inside, it is suitable for sliding along the pipe body under the drive of the nut, and the sliding ring is connected with the pulling wire.

In the above structure, turning the screw nut can make the screw nut reciprocate on the threaded end. During this process, the screw nut can drag the sliding weight and reciprocate outside the tube body at the same time, because the sliding ring is connected to one end of the pulling wire , the sliding ring can further drive the traction line to reciprocate. Since the nut and the pipe body are connected by threads and are set outside the pipe body, there is a certain resistance, so the traction wire cannot actively drive the nut to move by virtue of the elasticity of the petal. Therefore, the above-mentioned structure can keep the petal-like member from opening to a certain angle and not change, thereby achieving the purpose of controlling the opening degree of the expansion end.

3. In the thrombectomy catheter provided by the present application, the pulling wire passes through the tube body and is relatively slidably arranged with the tube body. The design of the pull wire passing through the tube body, on the one hand, can make the entire thrombectomy catheter more neat and easy to enter the blood vessel; Knotting, winding, etc., can also make the pulling action of the pulling wire more stable and controllable.

4. In the thrombectomy catheter provided by the present application, the pulling wire is connected to the side of the petal part away from the exposed end. Compared with the pulling wire connected to the root of the petal, this reduces the sensitivity of the opening movement of the petal to the pulling action of the pulling wire, so that the pulling wire can more accurately control the opening degree of the petal.

5. In the thrombectomy catheter provided by the present application, there are at least three petals. More petals can make the shape of the expansion end closer to a circle after being expanded, and the circular expansion end can better fit the inner wall of the blood vessel and reduce the pain of the patient. Therefore, at least three petals are necessary.

6. In the thrombectomy catheter provided by the present application, different petals are overlapped with each other, and the same petal is respectively lapped on the inside and outside of the other two petals that are immediately adjacent to it. In the above structure, the different petals can push and rub against each other during the movement, so that the opening actions of the multiple petals are more synchronized. On the other hand, after the overlapping petals are opened, the gap between the outer edges of the petals can be made smaller and approach a complete circle.

7. In the thrombectomy catheter provided by the present application, the expansion end further includes: an elastic section, which is wrapped around the outside of the petal, and is suitable for being driven to expand elastically when the petal is opened. In the above structure, the elastic section covers the outside of the petal, and when the petal is opened, it will drive the elastic section to expand together, so that the elastic section forms a coherent whole that is approximately circular. In this way, it is possible to prevent the valve-shaped part from stinging the blood vessel and reduce the pain of the patient.

To sum up, the thrombectomy catheter provided by the present application can control the opening width of the thrombectomy site of the catheter, can meet the needs of blood vessels of different thicknesses, and also has the advantages of less pain for patients and stable operation.

Description of drawings

In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the following will briefly introduce the accompanying drawings that need to be used in the description of the specific embodiments or prior art. Obviously, the accompanying drawings in the following description The drawings are some implementations of the present application, and those skilled in the art can obtain other drawings based on these drawings without creative work.

Figure 1 is a perspective view of the thrombectomy catheter provided in Example 1 of the present application;

Fig. 2 is a schematic cross-sectional structure diagram of the thrombectomy catheter shown in Fig. 1, in which the pipe body part uses the omitted drawing method;

Fig. 3 is a partially enlarged view of the traction member in the thrombectomy catheter shown in Fig. 2;

Fig. 4 is a partial enlarged view of the expanded end portion of the thrombectomy catheter shown in Fig. 2;

Fig. 5 is a perspective view of the expansion end portion shown in Fig. 4;

Fig. 6 is a schematic diagram of the structure after the expansion end shown in Fig. 5 is opened;

Explanation of reference signs:

1-base, 2-tube body, 3-expansion end, 4-exposed end, 5-petal piece, 6-pull line, 7-thread section, 8-screw nut, 9-sliding ring, 10-elastic section .

detailed description

The technical solutions of the present application will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are some of the embodiments of the present application, not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of this application.

In the description of this application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, or in a specific orientation. construction and operation, therefore should not be construed as limiting the application. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.

In the description of this application, it should be noted that unless otherwise specified and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. Connected, or integrally connected; it can be mechanically connected or electrically connected; it can be directly connected or indirectly connected through an intermediary, and it can be the internal communication of two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in this application in specific situations.

In addition, the technical features involved in the different embodiments of the present application described below may be combined as long as they do not constitute a conflict with each other.

Example:

Referring to Fig. 1 to Fig. 6, it is Embodiment 1 provided by the present application. This embodiment provides a thrombectomy catheter, which includes a tube body 2 and a base 1 . The end of the tube body 2 that enters the blood vessel during thrombectomy is the expansion end 3 . The exposed end 4 is the end left outside the human body during the thrombectomy on the tube body 2 . The exposed end 4 is opposite to the expanded end 3 . The base 1 is arranged on the exposed end 4 of the tube body 2 and is cylindrical, and the base 1 communicates with the tube body 2 .

In order to control the expansion range of the expansion end 3, the expansion end 3 includes at least three petals 5, the petals 5 are arranged at the end of the tube body 2, and the petals 5 can be lowered under the action of the pulling wire 6. Open to the periphery of tube body 2. The cross section of the petal member 5 is arc-shaped. Different petals 5 are overlapped with each other, and the same petal 5 is respectively lapped on the inside and outside of the other two petals 5 adjacent to it. More petals 5 can make the expanded shape of the expansion end 3 closer to a circle, and the circular expansion end 3 can better fit the inner wall of the blood vessel, reducing the pain of the patient. Therefore, at least three petals 5 It's required. The overlapping design of the different petal-shaped parts 5 can make the different petal-like parts 5 push and rub against each other during the movement, so that the opening action of the multiple petal-like parts 5 is more synchronized. On the other hand, after the petals 5 overlapping each other are opened, the gap between the outer edges of the petals 5 can be made smaller and approach a complete circle more.

In order not to sting the blood vessel after the expansion end 3 is opened, an elastic section 10 is also provided at the expansion end 3 of the tube body 2, and the elastic section 10 is wrapped around the outside of the petal-shaped part 5, and is suitable for being held by the petal-shaped part 5 when it is opened. Driven to expand elastically.

One end of the pulling wire 6 is connected to the petal 5 , specifically, the pulling wire 6 is connected to a side of the petal 5 away from the exposed end 4 . Compared with the connection between the pulling wire 6 and the root of the petal-like member 5, this reduces the sensitivity of the opening movement of the petal-like member 5 to the pulling action of the pulling wire 6, so that the pulling wire 6 can control the petal-like member 5 more precisely. degree of opening. The other end of the pulling wire 6 passes through the pipe body 2 , is slidably arranged relative to the pipe body 2 , extends to the exposed end 4 of the pipe body 2 , and is connected to the pulling member. The traction member is arranged on the exposed end 4 of the pipe body 2, connected with the traction line 6, suitable for dragging the traction line 6, and fixing the dragging length of the traction line 6. The traction member includes a threaded segment 7 , a screw nut 8 and a sliding ring 9 . The threaded section 7 is arranged on the exposed end 4 of the pipe body 2; the thread nut 8 is set on the outside of the pipe body 2 and meshed with the threaded section 7; the sliding ring 9 is set on the outside of the pipe body 2, and the sliding ring 9 is embedded in the thread nut 8, suitable for sliding along the pipe body 2 under the drive of the screw nut 8, and the sliding ring 9 is connected with the pulling wire 6.

Rotating the screw nut 8 can make the screw nut 8 reciprocate on the threaded end. In the process, the screw nut 8 can drag the sliding right and reciprocate outside the tube body 2 at the same time. Because the sliding ring 9 and one end of the pulling wire 6 Connected, the sliding ring 9 can further drive the traction line 6 to reciprocate. Since the thread nut 8 and the pipe body 2 are threadedly connected, and are set outside the pipe body 2, there is a certain resistance, so the pulling wire 6 cannot actively drive the thread nut 8 to move by virtue of the elasticity of the petal-shaped part 5 . Therefore, the above-mentioned structure can keep the petal-like member 5 open to a certain angle and not change, and then achieve the purpose of controlling the opening degree of the expansion end 3 .

The action principle of the above-mentioned thrombectomy catheter is:

When the catheter enters the blood vessel, the screw nut 8 is rotated to drive the sliding ring 9 to move along the tube body 2, and then pull the traction wire 6. Pulling the traction wire 6 can open the petal 5 located at the front end of the tube body 2, and then open the front end of the catheter to prop up the blood vessel. At this time, adjusting the pull-out length of the pulling wire 6 can control the opening range of the petal member 5 , so that the opening range of the entire expansion end 3 can be controlled. When operating on blood vessels of different thicknesses, it can meet their needs.

Apparently, the above-mentioned embodiments are only examples for clear description, rather than limiting the implementation. For those of ordinary skill in the art, other changes or changes in different forms can be made on the basis of the above description. It is not necessary and impossible to exhaustively list all the implementation manners here. However, the obvious changes or changes derived therefrom are still within the scope of protection of the present application.

Claims

A thrombectomy catheter, characterized in that it comprises:

Tube body;

The expansion end, located at one end of the tube body, is suitable for entering the blood vessel during thrombectomy;

The exposed end is located on the other end of the tube body opposite to the expanded end, and is suitable for staying outside the human body during thrombectomy;

A traction line, one end of which is connected to the petal, and the other end extends to the exposed end of the tube body;

Several petals at the expansion end are arranged at the end of the tube body;

The petals are adapted to expand toward the outer periphery of the tube body under the traction of the traction wire.
The thrombectomy catheter according to claim 1, further comprising:

The traction member is arranged on the exposed end of the pipe body, connected with the traction line, suitable for pulling the traction line, and fixing the dragging length of the traction line.
The thrombectomy catheter according to claim 2, wherein the traction member comprises:

The threaded section is arranged on the exposed end of the pipe body;

The screw nut is set on the outside of the pipe body and engages with the threaded section;

The sliding ring is set on the outside of the pipe body, the sliding ring is embedded in the nut, and is suitable for sliding along the pipe body driven by the nut, and the sliding ring is connected with the pulling wire.
The thrombectomy catheter according to claim 1, wherein the pulling wire passes through the tube body and is relatively slidably arranged with the tube body.
The thrombectomy catheter according to claim 1, wherein the pulling wire is connected to a side of the petal part away from the exposed end.
The thrombectomy catheter according to claim 1, wherein there are at least three petals.
The thrombectomy catheter according to claim 1, wherein the cross section of the petal is arc-shaped.
The thrombectomy catheter according to claim 6, characterized in that different petal-shaped parts overlap each other, and the same petal-shaped part overlaps the inner side and outer side of the other two petal-like parts which are adjacent to it respectively.
The thrombectomy catheter according to claim 1, wherein the expansion end further comprises:

The elastic segment is wrapped on the outside of the petal, and is suitable for being driven to expand elastically when the petal is opened.
The thrombectomy catheter according to any one of claims 1 to 9, further comprising:

The base is arranged on the exposed end of the tube body and communicates with the tube body.