WO2022246002A3 - Methods and compositions for determining cancer risk - Google Patents

Methods and compositions for determining cancer risk Download PDF

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Publication number
WO2022246002A3
WO2022246002A3 PCT/US2022/029913 US2022029913W WO2022246002A3 WO 2022246002 A3 WO2022246002 A3 WO 2022246002A3 US 2022029913 W US2022029913 W US 2022029913W WO 2022246002 A3 WO2022246002 A3 WO 2022246002A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
cancer risk
determining cancer
determining
Prior art date
Application number
PCT/US2022/029913
Other languages
French (fr)
Other versions
WO2022246002A2 (en
Inventor
Ajay Goel
Satoshi NISHIWADA
Original Assignee
City Of Hope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by City Of Hope filed Critical City Of Hope
Publication of WO2022246002A2 publication Critical patent/WO2022246002A2/en
Publication of WO2022246002A3 publication Critical patent/WO2022246002A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Provided herein are methods and compositions for detecting and treating a micrometastatic disease in a subject who has or is suspected of having a cancer.
PCT/US2022/029913 2021-05-20 2022-05-18 Methods and compositions for determining cancer risk WO2022246002A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163191251P 2021-05-20 2021-05-20
US63/191,251 2021-05-20

Publications (2)

Publication Number Publication Date
WO2022246002A2 WO2022246002A2 (en) 2022-11-24
WO2022246002A3 true WO2022246002A3 (en) 2022-12-15

Family

ID=84140804

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/029913 WO2022246002A2 (en) 2021-05-20 2022-05-18 Methods and compositions for determining cancer risk

Country Status (1)

Country Link
WO (1) WO2022246002A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140141423A1 (en) * 2008-02-08 2014-05-22 Asuragen, Inc. miRNAs Differentially Expressed in Lymph Nodes from Cancer Patients
US20200222446A1 (en) * 2017-01-23 2020-07-16 Trustees Of Boston University Methods relating to lung cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140141423A1 (en) * 2008-02-08 2014-05-22 Asuragen, Inc. miRNAs Differentially Expressed in Lymph Nodes from Cancer Patients
US20200222446A1 (en) * 2017-01-23 2020-07-16 Trustees Of Boston University Methods relating to lung cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GABLO NATALIA, TRACHTOVA KAROLINA, PROCHAZKA VLADIMIR, HLAVSA JAN, GROLICH TOMAS, KISS IGOR, SROVNAL JOSEF, REHULKOVA ALONA, LOVEC: "Identification and Validation of Circulating Micrornas as Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma Patients Undergoing Surgical Resection", JOURNAL OF CLINICAL MEDICINE, vol. 9, no. 8, 30 July 2020 (2020-07-30), XP093016461, DOI: 10.3390/jcm9082440 *

Also Published As

Publication number Publication date
WO2022246002A2 (en) 2022-11-24

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