WO2022235934A3 - Realizing the nano-amorphous state of materials inside nano-porous templates - Google Patents

Realizing the nano-amorphous state of materials inside nano-porous templates Download PDF

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Publication number
WO2022235934A3
WO2022235934A3 PCT/US2022/027873 US2022027873W WO2022235934A3 WO 2022235934 A3 WO2022235934 A3 WO 2022235934A3 US 2022027873 W US2022027873 W US 2022027873W WO 2022235934 A3 WO2022235934 A3 WO 2022235934A3
Authority
WO
WIPO (PCT)
Prior art keywords
nano
porous templates
realizing
materials inside
amorphous state
Prior art date
Application number
PCT/US2022/027873
Other languages
French (fr)
Other versions
WO2022235934A2 (en
Inventor
Lei Xu
David Weitz
Zhuo XU
Changliang Zhu
Original Assignee
The Chinese University Of Hong Kong
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/313,528 external-priority patent/US20220354796A1/en
Priority claimed from CN202110490559.7A external-priority patent/CN115300448A/en
Application filed by The Chinese University Of Hong Kong, President And Fellows Of Harvard College filed Critical The Chinese University Of Hong Kong
Priority to EP22799596.6A priority Critical patent/EP4333817A2/en
Publication of WO2022235934A2 publication Critical patent/WO2022235934A2/en
Publication of WO2022235934A3 publication Critical patent/WO2022235934A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Powder Metallurgy (AREA)

Abstract

The subject invention pertains to methods to produce amorphous materials at nanometer scale, by solidifying or hardening the materials inside nanometer-sized pores of porous media (i.e., porous templates). The porous templates can be made by packing nanometer-sized particles or other means. The subject invention further pertains to methods to produce the porous templates used to produce amorphous material at nanometer scale.
PCT/US2022/027873 2021-05-06 2022-05-05 Realizing the nano-amorphous state of materials inside nano-porous templates WO2022235934A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22799596.6A EP4333817A2 (en) 2021-05-06 2022-05-05 Realizing the nano-amorphous state of materials inside nano-porous templates

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17/313,528 2021-05-06
US17/313,528 US20220354796A1 (en) 2021-05-06 2021-05-06 Realizing the nano-amorphous state of materials inside nano-porous templates
CN202110490559.7 2021-05-06
CN202110490559.7A CN115300448A (en) 2021-05-06 2021-05-06 Achieving nano-amorphous state of materials within nano-porous templates

Publications (2)

Publication Number Publication Date
WO2022235934A2 WO2022235934A2 (en) 2022-11-10
WO2022235934A3 true WO2022235934A3 (en) 2024-04-04

Family

ID=83932488

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/027873 WO2022235934A2 (en) 2021-05-06 2022-05-05 Realizing the nano-amorphous state of materials inside nano-porous templates

Country Status (2)

Country Link
EP (1) EP4333817A2 (en)
WO (1) WO2022235934A2 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020034827A1 (en) * 2000-08-01 2002-03-21 Rajendra Singh Methods for solid phase nanoextraction and desorption
US6790528B2 (en) * 2000-08-18 2004-09-14 Transmit Gesellschaft Fuer Technologietransfer Mbh Production of polymer fibres having nanoscale morphologies
US20090118821A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis with porous reservoir and non-polymer diffusion layer
US20110177231A1 (en) * 2010-01-16 2011-07-21 Alexander Grinberg Nano-, Micro-, Macro- Encapsulation And Release Of Materials
US8778401B2 (en) * 2008-10-28 2014-07-15 Agency For Science, Technology And Research Mesoporous material excipients for poorly aqueous soluble ingredients
US8815273B2 (en) * 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US20190127232A1 (en) * 2016-04-04 2019-05-02 Disruptive Materials Ab Highly porous magnesium carbonate and method of production thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020034827A1 (en) * 2000-08-01 2002-03-21 Rajendra Singh Methods for solid phase nanoextraction and desorption
US6790528B2 (en) * 2000-08-18 2004-09-14 Transmit Gesellschaft Fuer Technologietransfer Mbh Production of polymer fibres having nanoscale morphologies
US8815273B2 (en) * 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US20090118821A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis with porous reservoir and non-polymer diffusion layer
US8778401B2 (en) * 2008-10-28 2014-07-15 Agency For Science, Technology And Research Mesoporous material excipients for poorly aqueous soluble ingredients
US20110177231A1 (en) * 2010-01-16 2011-07-21 Alexander Grinberg Nano-, Micro-, Macro- Encapsulation And Release Of Materials
US20190127232A1 (en) * 2016-04-04 2019-05-02 Disruptive Materials Ab Highly porous magnesium carbonate and method of production thereof

Also Published As

Publication number Publication date
WO2022235934A2 (en) 2022-11-10
EP4333817A2 (en) 2024-03-13

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